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Cyclin E modulates vulnerability to CDC7 kinase inhibition

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1. scibot 13 Jun 2026
  
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  DOI: 10.1038/s41389-026-00613-5
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13243581/
Dec 2025
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Anti-Cancer Effects of the Ethyl Acetate Fraction From Opuntia humifusa on Human Triple-Negative Breast Cancer Cells

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pmc.ncbi.nlm.nih.gov/articles/PMC12705953/
Nov 2025
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CDK7 is a novel therapeutic target in fibrolamellar carcinoma

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1. scibot 22 Nov 2025
  
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sciencedirect.com/science/article/pii/S2589004225021868
Oct 2025
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hsu-et-al-2025-phosphoproteomics-of-osimertinib-tolerant-persister-cells-reveals-targetable-kinase-substrate-signatures-html.html

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54.241.53.176/9c78a41645fcc9eb1ef3871f95e64fd70faf70c8/hsu-et-al-2025-phosphoproteomics-of-osimertinib-tolerant-persister-cells-reveals-targetable-kinase-substrate-signatures-html.html
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Phosphoproteomics of osimertinib-tolerant persister cells reveals targetable kinase-substrate signatures

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embopress.org/doi/10.1038/s44320-025-00141-1
May 2025
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Circular RNA circATM binds PARP1 to suppress Wnt/β-catenin signaling and induce cell cycle arrest in gastric cancer cells

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sciencedirect.com/science/article/pii/S2090123225002772
Jan 2025
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CDKN2A/B homozygous deletion sensitizes IDH-mutant glioma to CDK4/6 inhibition

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pmc.ncbi.nlm.nih.gov/articles/PMC11250907/
Jun 2024
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Plexin D1 emerges as a novel target in the development of neural lineage plasticity in treatment-resistant prostate cancer

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1. scibot 28 Jun 2024
  
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May 2024
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The MYCN oncoprotein is an RNA-binding accessory factor of the nuclear exosome targeting complex

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Apr 2024
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Plexin D1 emerges as a novel target in the development of neural lineage plasticity in treatment-resistant prostate cancer

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  DOI: 10.21203/rs.3.rs-4095949/v1
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10996809/
Feb 2024
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Sphingolipid metabolism controls mammalian heart regeneration

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sciencedirect.com/science/article/pii/S1550413124000172
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Integrative modeling uncovers p21-driven drug resistance and prioritizes therapies for PIK3CA-mutant breast cancer

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  DOI: 10.1038/s41698-024-00496-y
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10810864/
Jan 2024
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In silico protein interaction screening uncovers DONSON’s role in replication initiation

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1. scibot 24 Jan 2024
  
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  DOI: 10.1126/science.adi3448
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10801813/
Dec 2023
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Design, synthesis and mechanistic anticancer activity of new acetylated 5-aminosalicylate-thiazolinone hybrid derivatives

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1. scibot 29 Dec 2023
  
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  DOI: 10.1016/j.isci.2023.108659
  
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sciencedirect.com/science/article/pii/S2589004223027360
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Transgelin Promotes Glioblastoma Stem Cell Hypoxic Responses and Maintenance Through p53 Acetylation

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1. scibot 29 Dec 2023
  
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  DOI: 10.1002/advs.202305620
  
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onlinelibrary.wiley.com/doi/10.1002/advs.202305620
Oct 2023
52.53.155.43 52.53.155.43

ccr-23-0103-html.html

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1. scibot 07 Oct 2023
  
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  DOI: 10.1158/1078-0432.ccr-23-0103
  
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52.53.155.43/05abf3a0903b8473a428373dc7a2f791e1da90bb/ccr-23-0103-html.html
Aug 2023
www.science.org www.science.org

In silico protein interaction screening uncovers DONSON’s role in replication initiation

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1. scibot 29 Aug 2023
  
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  DOI: 10.1126/science.adi3448
  
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science.org/doi/10.1126/science.adi3448
52.53.155.43 52.53.155.43

ccr-23-0103-html.html

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1. scibot 11 Aug 2023
  
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52.53.155.43/05abf3a0903b8473a428373dc7a2f791e1da90bb/ccr-23-0103-html.html
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FRMD8 targets both CDK4 activation and RB degradation to suppress colon cancer growth

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1. scibot 03 Aug 2023
  
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  DOI: 10.1016/j.celrep.2023.112886
  
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sciencedirect.com/science/article/pii/S2211124723008975
Jul 2023
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Co-targeting RANK pathway treats and prevents acquired resistance to CDK4/6 inhibitors in luminal breast cancer

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  DOI: 10.1016/j.xcrm.2023.101120
  
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sciencedirect.com/science/article/pii/S2666379123002483
52.53.155.43 52.53.155.43

ccr-23-0103-html.html

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52.53.155.43/05abf3a0903b8473a428373dc7a2f791e1da90bb/ccr-23-0103-html.html
May 2023
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Modeling breast cancer proliferation, drug synergies, and alternating therapies

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1. scibot 19 May 2023
  
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  DOI: 10.1016/j.isci.2023.106714
  
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sciencedirect.com/science/article/pii/S2589004223007915
Feb 2023
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Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity

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  DOI: 10.1016/j.molcel.2023.01.015
  
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sciencedirect.com/science/article/pii/S1097276523000382
Jan 2023
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Plakophilin 3 facilitates G1/S phase transition and enhances proliferation by capturing RB protein in the cytoplasm and promoting EGFR signaling

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  DOI: 10.1016/j.celrep.2023.112031
  
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sciencedirect.com/science/article/pii/S2211124723000426
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Loss of VOPP1 Contributes to BET Inhibitor Acquired Resistance in Non–Small Cell Lung Cancer Cells

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  DOI: 10.1158/1541-7786.MCR-21-1000
  
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aacrjournals.org/mcr/article/20/12/1785/710999/Loss-of-VOPP1-Contributes-to-BET-Inhibitor
Aug 2022
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Analysis of neuroendocrine clones in NSCLCs using an immuno-guided laser-capture microdissection-based approach

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  DOI: 10.1016/j.crmeth.2022.100271
  
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sciencedirect.com/science/article/pii/S2667237522001485
Mar 2022
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BPS Publications

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1. scibot 31 Mar 2022
  
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  RRID:AB_2276129
  
  DOI: 10.1111/bph.14558
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.14558
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Methylene-bridge tryptophan fatty acylation regulates PI3K-AKT signaling and glucose uptake

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  DOI: 10.1016/j.celrep.2022.110509
  
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sciencedirect.com/science/article/pii/S2211124722002455
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Moderate heart rate reduction promotes cardiac regeneration through stimulation of the metabolic pattern switch

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sciencedirect.com/science/article/pii/S2211124722002017
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CDK/cyclin dependencies define extreme cancer cell-cycle heterogeneity and collateral vulnerabilities

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  DOI: 10.1016/j.celrep.2022.110448
  
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sciencedirect.com/science/article/pii/S2211124722001759
Jan 2022
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WEE1 kinase protects the stability of stalled DNA replication forks by limiting CDK2 activity

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  DOI: 10.1016/j.celrep.2021.110261
  
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sciencedirect.com/science/article/pii/S2211124721017733
Nov 2021
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RNA-binding protein FXR1 drives cMYC translation by recruiting eIF4F complex to the translation start site

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1. scibot 03 Nov 2021
  
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  DOI: 10.1016/j.celrep.2021.109934
  
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sciencedirect.com/science/article/pii/S2211124721014078
Sep 2021
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CCNE1 copy number is a biomarker for response to combination WEE1-ATR inhibition in ovarian and endometrial cancer models

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1. scibot 25 Sep 2021
  
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  DOI: 10.1016/j.xcrm.2021.100394
  
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pmc.ncbi.nlm.nih.gov/articles/PMC8484689/
Aug 2021
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Untitled document

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1. scibot 10 Aug 2021
  
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  DOI: 10.1111/bph.14558
  
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bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.14558
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1. scibot 01 Aug 2021
  
  in Public
  
  RRID:AB_2276129
  
  DOI: 10.1155/2019/6254269
  
  Resource: (Cell Signaling Technology Cat# 2546, RRID:AB_2276129)
  
  Curator: @scibot
  
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hindawi.com/journals/sci/2019/6254269/
Jul 2021
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RASAL1 induces to downregulate the SCD1, leading to suppression of cell proliferation in colon cancer via LXRα/SREBP1c pathway

1
1. scibot 31 Jul 2021
  
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  CDK2
  
  DOI: 10.1186/s40659-019-0268-x
  
  Resource: (Cell Signaling Technology Cat# 2546, RRID:AB_2276129)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2276129
  
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  RRID:AB_2276129 RRIDCUR:Missing
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link.springer.com/article/10.1186/s40659-019-0268-x
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Targeted protein degradation reveals a direct role of SPT6 in RNAPII elongation and termination

1
1. scibot 09 Jul 2021
  
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  RRID:AB_2276129
  
  DOI: 10.1016/j.molcel.2021.06.016
  
  Resource: (Cell Signaling Technology Cat# 2546, RRID:AB_2276129)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S1097276521004962
May 2021
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Cell size homeostasis is maintained by CDK4-dependent activation of p38 MAPK

1
1. scibot 22 May 2021
  
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  RRID:AB_2276129
  
  DOI: 10.1016/j.devcel.2021.04.030
  
  Resource: (Cell Signaling Technology Cat# 2546, RRID:AB_2276129)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S1534580721003993
Apr 2021
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Y box binding protein 1 inhibition as a targeted therapy for ovarian cancer

1
1. scibot 28 Apr 2021
  
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  RRID: AB_2276129
  
  DOI: 10.1016/j.chembiol.2021.02.014
  
  Resource: (Cell Signaling Technology Cat# 2546, RRID:AB_2276129)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2276129
  
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sciencedirect.com/science/article/pii/S2451945621000994
Jan 2021
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A novel ligand of the translationally controlled tumor protein (TCTP) identified by virtual drug screening for cancer differentiation therapy

1
1. scibot 28 Jan 2021
  
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  RRID:AB_2276129
  
  DOI: 10.1007/s10637-020-01042-w
  
  Resource: (Cell Signaling Technology Cat# 2546, RRID:AB_2276129)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2276129
  
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  RRIDCUR:Validated RRID:AB_2276129
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link.springer.com/article/10.1007/s10637-020-01042-w
Nov 2020
link.springer.com link.springer.com

p75NTR Promotes Astrocyte Proliferation in Response to Cortical Stab Wound

1
1. scibot 25 Nov 2020
  
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  anti-CDK2
  
  DOI: 10.1007/s10571-020-01006-x
  
  Resource: (Cell Signaling Technology Cat# 2546, RRID:AB_2276129)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2276129
  
  Curator comments: CDK2 (78B2) Rabbit mAb antibody Cell Signaling Technology Cat# 2546
  
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  RRIDCUR:Missing RRID:AB_2276129
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link.springer.com/article/10.1007/s10571-020-01006-x
Jan 2020
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CDK7 Inhibition Potentiates Genome Instability Triggering Anti-tumor Immunity in Small Cell Lung Cancer

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2276129
  
  DOI: 10.1016/j.ccell.2019.11.003
  
  Resource: (Cell Signaling Technology Cat# 2546, RRID:AB_2276129)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2276129
  
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  RRID:AB_2276129 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1535610819305239
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Conserved Herpesvirus Protein Kinases Target SAMHD1 to Facilitate Virus Replication

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2276129
  
  DOI: 10.1016/j.celrep.2019.04.020
  
  Resource: (Cell Signaling Technology Cat# 2546, RRID:AB_2276129)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2276129
  
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  RRID:AB_2276129 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124719304851
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Untitled document

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_2276129
  
  DOI: 10.1016/j.chembiol.2019.02.015
  
  Resource: (Cell Signaling Technology Cat# 2546, RRID:AB_2276129)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2276129
  
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  RRID:AB_2276129 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2451945619300704
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Untitled document

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_2276129
  
  DOI: 10.1016/j.celrep.2019.01.111
  
  Resource: (Cell Signaling Technology Cat# 2546, RRID:AB_2276129)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2276129
  
  What is this?
  
  RRID:AB_2276129 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124719301482
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_2276129
  
  DOI: 10.1155/2019/6254269
  
  Resource: (Cell Signaling Technology Cat# 2546, RRID:AB_2276129)
  
  Curator: @evieth
  
  SciCrunch record: RRID:AB_2276129
  
  What is this?
  
  RRID:AB_2276129 RRIDCUR:Validated
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ncbi.nlm.nih.gov/pmc/articles/PMC6409035/
Nov 2018
onlinelibrary.wiley.com onlinelibrary.wiley.com

Testosterone regulates myosin II isoforms expression and functional activity in the rat prostate

1
1. scibot 05 Nov 2018
  
  in Public
  
  AB_2276129
  
  Curator: @anp055
  
  Curator note: Emailed Mason: our record said antigen = CDK3, while it should be CDK2
  
  Resource used:
  
  (Cell Signaling Technology Cat# 2546, RRID:AB_2276129)
  
  SciCrunch record: RRID:AB_2276129
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:AB_2276129 RRIDCUR:Validated
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onlinelibrary.wiley.com/doi/full/10.1002/pros.23702
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Mutant p53 Gains Its Function via c-Myc Activation upon CDK4 Phosphorylation at Serine 249 and Consequent PIN1 Binding

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:AB_2276129
  
  Resource used:
  
  (Cell Signaling Technology Cat# 2546, RRID:AB_2276129)
  
  SciCrunch record: RRID:AB_2276129
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:AB_2276129
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RRID:AB_2276129

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sciencedirect.com/science/article/pii/S1097276517308419