Hypothesis

18 Matching Annotations

May 2024
www.sciencedirect.com www.sciencedirect.com

Targeting MCL1-driven anti-apoptotic pathways overcomes blast progression after hypomethylating agent failure in chronic myelomonocytic leukemia

1
1. scibot 23 May 2024
  
  in Public
  
  RRID:AB_2281980
  
  DOI: 10.1016/j.xcrm.2024.101585
  
  Resource: (Cell Signaling Technology Cat# 4572, RRID:AB_2281980)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2281980
  
  What is this?
  
  RRID:AB_2281980
Visit annotations in context

Tags

RRID:AB_2281980

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2666379124002775
Nov 2023
www.sciencedirect.com www.sciencedirect.com

Allosteric SHP2 inhibition increases apoptotic dependency on BCL2 and synergizes with venetoclax in FLT3- and KIT-mutant AML

1
1. scibot 22 Nov 2023
  
  in Public
  
  RRID:AB_2281980
  
  DOI: 10.1016/j.xcrm.2023.101290
  
  Resource: (Cell Signaling Technology Cat# 4572, RRID:AB_2281980)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2281980
  
  What is this?
  
  RRID:AB_2281980
Visit annotations in context

Tags

RRID:AB_2281980

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2666379123004846
Jan 2023
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

Artesunate, a new antimalarial clinical drug, exhibits potent anti-AML activity by targeting the ROS/Bim and TFRC/Fe2+ pathways

1
1. scibot 14 Jan 2023
  
  in Public
  
  RRID:AB_2281980
  
  DOI: 10.1111/bph.15986
  
  Resource: (Cell Signaling Technology Cat# 4572, RRID:AB_2281980)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2281980
  
  What is this?
  
  RRID:AB_2281980
Visit annotations in context

Tags

RRID:AB_2281980

Annotators

scibot

URL

bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15986
Sep 2022
www.sciencedirect.com www.sciencedirect.com

BET inhibition induces vulnerability to MCL1 targeting through upregulation of fatty acid synthesis pathway in breast cancer

1
1. scibot 15 Sep 2022
  
  in Public
  
  RRID:AB_2281980
  
  DOI: 10.1016/j.celrep.2022.111304
  
  Resource: (Cell Signaling Technology Cat# 4572, RRID:AB_2281980)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2281980
  
  What is this?
  
  RRID:AB_2281980
Visit annotations in context

Tags

RRID:AB_2281980

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124722011287
Mar 2022
elifesciences.org elifesciences.org

Confined migration promotes cancer metastasis through resistance to anoikis and increased invasiveness

1
1. scibot 11 Mar 2022
  
  in Public
  
  RRID:AB_2281980
  
  DOI: 10.7554/eLife.73150
  
  Resource: (Cell Signaling Technology Cat# 4572, RRID:AB_2281980)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2281980
  
  What is this?
  
  RRID:AB_2281980
Visit annotations in context

Tags

RRID:AB_2281980

Annotators

scibot

URL

elifesciences.org/articles/73150
Feb 2022
www.sciencedirect.com www.sciencedirect.com

A FBXO7/EYA2-SCFFBXW7 axis promotes AXL-mediated maintenance of mesenchymal and immune evasion phenotypes of cancer cells

1
1. scibot 23 Feb 2022
  
  in Public
  
  RRID:AB_2281980
  
  DOI: 10.1016/j.molcel.2022.01.022
  
  Resource: (Cell Signaling Technology Cat# 4572, RRID:AB_2281980)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2281980
  
  What is this?
  
  RRID:AB_2281980
Visit annotations in context

Tags

RRID:AB_2281980

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1097276522000879
www.sciencedirect.com www.sciencedirect.com

BCL-XL inhibition induces an FGFR4-mediated rescue response in colorectal cancer

1
1. scibot 16 Feb 2022
  
  in Public
  
  AB_2281980
  
  DOI: 10.1016/j.celrep.2022.110374
  
  Resource: (Cell Signaling Technology Cat# 4572, RRID:AB_2281980)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2281980
  
  What is this?
  
  RRID:AB_2281980
Visit annotations in context

Tags

RRID:AB_2281980

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S221112472200095X
Jul 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Combined inhibition of the PI3K/mTOR/MEK pathway induces Bim/Mcl-1-regulated apoptosis in pancreatic cancer cells

1
1. scibot 29 Jul 2021
  
  in Public
  
  AB_2281980
  
  DOI: 10.1080/15384047.2018.1504718
  
  Resource: (Cell Signaling Technology Cat# 4572, RRID:AB_2281980)
  
  Curator: @bandrow
  
  SciCrunch record: RRID:AB_2281980
  
  What is this?
  
  RRID:AB_2281980 RRIDCUR:Unrecognized
Visit annotations in context

Tags

RRID:AB_2281980

RRIDCUR:Unrecognized

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC6343713/
www.sciencedirect.com www.sciencedirect.com

Degradation of CCNK/CDK12 is a druggable vulnerability of colorectal cancer

1
1. scibot 22 Jul 2021
  
  in Public
  
  RRID:AB_2281980
  
  DOI: 10.1016/j.celrep.2021.109394
  
  Resource: (Cell Signaling Technology Cat# 4572, RRID:AB_2281980)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2281980
  
  What is this?
  
  RRID:AB_2281980
Visit annotations in context

Tags

RRID:AB_2281980

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124721007920
May 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Ethanol Enhances Hyperthermia-Induced Cell Death in Human Leukemia Cells

1
1. scibot 19 May 2021
  
  in Public
  
  RRID:AB_2281980
  
  DOI: 10.3390/ijms22094948
  
  Resource: (Cell Signaling Technology Cat# 4572, RRID:AB_2281980)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2281980
  
  What is this?
  
  RRID:AB_2281980
Visit annotations in context

Tags

RRID:AB_2281980

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC8125413/
Feb 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

BCL-xL/BCL2L1 is a critical anti-apoptotic protein that promotes the survival of differentiating pancreatic cells from human pluripotent stem cells

1
1. scibot 25 Feb 2021
  
  in Public
  
  RRID:AB_2281980
  
  DOI: 10.1038/s41419-020-2589-7
  
  Resource: (Cell Signaling Technology Cat# 4572, RRID:AB_2281980)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2281980
  
  What is this?
  
  RRID:AB_2281980
Visit annotations in context

Tags

RRID:AB_2281980

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC7235254/
Oct 2020
www.sciencedirect.com www.sciencedirect.com

The mTORC1/S6K/PDCD4/eIF4A Axis Determines Outcome of Mitotic Arrest

1
1. scibot 07 Oct 2020
  
  in Public
  
  RRID:AB_2281980
  
  DOI: 10.1016/j.celrep.2020.108230
  
  Resource: (Cell Signaling Technology Cat# 4572, RRID:AB_2281980)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2281980
  
  What is this?
  
  RRIDCUR:Validated RRID:AB_2281980
Visit annotations in context

Tags

RRID:AB_2281980

RRIDCUR:Validated

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124720312195
Sep 2020
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

Synthesis, biological evaluation and toxicity of novel tetrandrine analogues

1
1. scibot 09 Sep 2020
  
  in Public
  
  Mcl-1
  
  DOI: 10.1016/j.ejmech.2020.112810
  
  Resource: (Cell Signaling Technology Cat# 4572, RRID:AB_2281980)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2281980
  
  Curator comments: Mcl-1 Antibody Cell Signaling Technology Cat# 4572
  
  What is this?
  
  RRID:AB_2281980 RRIDCUR:Missing
Visit annotations in context

Tags

RRID:AB_2281980

RRIDCUR:Missing

Annotators

scibot

URL

pubmed.ncbi.nlm.nih.gov/32942071/
Jan 2020
www.sciencedirect.com www.sciencedirect.com

The Cytoplasmic DNA Sensor cGAS Promotes Mitotic Cell Death

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_2281980
  
  DOI: 10.1016/j.cell.2019.05.035
  
  Resource: (Cell Signaling Technology Cat# 4572, RRID:AB_2281980)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2281980
  
  What is this?
  
  RRID:AB_2281980 RRIDCUR:Validated
Visit annotations in context

Tags

RRID:AB_2281980

RRIDCUR:Validated

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S009286741930563X
www.nature.com www.nature.com

ATG5 cancer mutations and alternative mRNA splicing reveal a conjugation switch that regulates ATG12–ATG5-ATG16L1 complex assembly and autophagy

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_2281980
  
  DOI: 10.1038/s41421-019-0110-1
  
  Resource: (Cell Signaling Technology Cat# 4572, RRID:AB_2281980)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2281980
  
  What is this?
  
  RRID:AB_2281980 RRIDCUR:Validated
Visit annotations in context

Tags

RRID:AB_2281980

RRIDCUR:Validated

Annotators

scibot

URL

nature.com/articles/s41421-019-0110-1
www.sciencedirect.com www.sciencedirect.com

Modeling of Cisplatin-Induced Signaling Dynamics in Triple-Negative Breast Cancer Cells Reveals Mediators of Sensitivity

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_2281980
  
  DOI: 10.1016/j.celrep.2019.07.070
  
  Resource: (Cell Signaling Technology Cat# 4572, RRID:AB_2281980)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2281980
  
  What is this?
  
  RRID:AB_2281980 RRIDCUR:Validated
Visit annotations in context

Tags

RRID:AB_2281980

RRIDCUR:Validated

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S221112471930974X
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Superior efficacy of cotreatment with BET protein inhibitor and BCL2 or MCL1 inhibitor against AML blast progenitor cells

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_2281980
  
  DOI: 10.1038/s41408-018-0165-5
  
  Resource: (Cell Signaling Technology Cat# 4572, RRID:AB_2281980)
  
  Curator: @evieth
  
  SciCrunch record: RRID:AB_2281980
  
  What is this?
  
  RRID:AB_2281980 RRIDCUR:Validated
Visit annotations in context

Tags

RRID:AB_2281980

RRIDCUR:Validated

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC6333829/
Nov 2018
www.tandfonline.com www.tandfonline.com

Combined inhibition of the PI3K/mTOR/MEK pathway induces Bim/Mcl-2-regulated apoptosis in pancreatic cancer cells

1
1. scibot 05 Nov 2018
  
  in Public
  
  AB_2281980
  
  Curator: @bandrow
  
  Resource used:
  
  (Cell Signaling Technology Cat# 4572, RRID:AB_2281980)
  
  SciCrunch record: RRID:AB_2281980
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:AB_2281980
Visit annotations in context

Tags

RRID:AB_2281980

Annotators

scibot

URL

tandfonline.com/doi/full/10.1080/15384047.2018.1504718