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Aug 2025
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Mitochondrial damage triggers the concerted degradation of negative regulators of neuronal autophagy

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  DOI: 10.1038/s41467-025-62379-5
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12335601/
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PALB2 and 53BP1 govern post-resection homologous recombination DNA repair

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  DOI: 10.1016/j.molcel.2025.07.003
  
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sciencedirect.com/science/article/pii/S1097276525006045
Jul 2025
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An Iron-regulated Signalling Pathway Controls Adipose Browning and Cancer Cachexia

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  DOI: 10.1101/2025.07.16.664180
  
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biorxiv.org/content/10.1101/2025.07.16.664180v1
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Bacterial ADP-heptose triggers stem cell regeneration in the intestinal epithelium following injury

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  DOI: 10.1016/j.stem.2025.06.009
  
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sciencedirect.com/science/article/pii/S1934590925002310
Mar 2025
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Cross-kingdom-mediated detection of intestinal protozoa through NLRP6

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  DOI: 10.1016/j.chom.2025.02.008
  
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sciencedirect.com/science/article/pii/S1931312825000563
Dec 2024
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1-s2.0-S2589004224027895-main-html.html

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52.53.155.43/115051ad15f7831b34f4faf1916680a9b8fdaa42/1-s2.0-S2589004224027895-main-html.html
Nov 2024
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Lysosomal damage triggers a p38 MAPK-dependent phosphorylation cascade to promote lysophagy via the small heat shock protein HSP27

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  DOI: 10.1016/j.cub.2024.10.061
  
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Jul 2024
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Aging Differentially Affects Axonal Autophagosome Formation and Maturation

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1. scibot 20 Jul 2024
  
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  DOI: 10.1080/15548627.2023.2236485
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10621248/
May 2024
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Initiation of acute pancreatitis in mice is independent of fusion between lysosomes and zymogen granules

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  DOI: 10.1007/s00018-024-05247-7
  
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link.springer.com/article/10.1007/s00018-024-05247-7
Apr 2024
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Adipocyte PI3K links adipostasis with baseline insulin secretion at fasting through an adipoincretin effect

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  DOI: 10.1016/j.celrep.2024.114132
  
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Islet resident macrophage-derived miR-155 promotes β-cell decompensation via targeting PDX1

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  DOI: 10.1016/j.isci.2024.109540
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10993184/
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Spastin locally amplifies microtubule dynamics to pattern the axon for presynaptic cargo delivery

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sciencedirect.com/science/article/pii/S0960982224003075
Mar 2024
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Stabilization of AMPK/PFKL/RPIA in the Glycolytic Bodies Transduces IL6/STAT3 Signal in Hepatocarcinogenesis

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1. scibot 21 Mar 2024
  
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  DOI: 10.1101/2024.02.29.582877
  
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biorxiv.org/content/10.1101/2024.02.29.582877v1
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Tumor acidosis-induced DNA damage response and tetraploidy enhance sensitivity to ATM and ATR inhibitors

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  DOI: 10.1038/s44319-024-00089-7
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10933359/
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Liver-derived plasminogen mediates muscle stem cell expansion during caloric restriction through the plasminogen receptor Plg-RKT

4
1. scibot 06 Mar 2024
  
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  DOI: 10.1016/j.celrep.2024.113881
  
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  DOI: 10.1016/j.celrep.2024.113881
  
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sciencedirect.com/science/article/pii/S2211124724002092
Feb 2024
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TMED2 promotes glioma tumorigenesis by being involved in EGFR recycling transport

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  DOI: 10.1016/j.ijbiomac.2024.130055
  
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sciencedirect.com/science/article/pii/S0141813024008584
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The GATOR2 complex maintains lysosomal-autophagic function by inhibiting the protein degradation of MiT/TFEs

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  DOI: 10.1016/j.molcel.2024.01.012
  
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sciencedirect.com/science/article/pii/S1097276524000480
Sep 2023
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The FASEB Journal - 2023 - Yamada (1)-html.html

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  DOI: 10.1096/fj.202300349r
  
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52.53.155.43/dc61cda424138f108e0da41b4205d6dd52d766de/The FASEB Journal - 2023 - Yamada (1)-html.html
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Muscle p62 stimulates the expression of antioxidant proteins alleviating cancer cachexia

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  DOI: 10.1096/fj.202300349R
  
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  DOI: 10.1096/fj.202300349R
  
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faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202300349R
Jul 2023
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Fidgetin interacting with microtubule end binding protein EB3 affects axonal regrowth in spinal cord injury

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1. scibot 22 Jul 2023
  
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  DOI: 10.4103/1673-5374.373716
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10358656/
Jun 2023
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Reduced acetylation of TFAM promotes bioenergetic dysfunction in the failing heart

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  DOI: 10.1016/j.isci.2023.106942
  
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May 2023
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Generation of endogenously tagged E-cadherin cells using gene editing via non-homologous end joining

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  DOI: 10.1016/j.xpro.2023.102305
  
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sciencedirect.com/science/article/pii/S2666166723002721
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PASK links cellular energy metabolism with a mitotic self-renewal network to establish differentiation competence

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1. scibot 09 May 2023
  
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  DOI: 10.7554/eLife.81717
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10162801/
faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com

PFKFB3-dependent glucose metabolism regulates 3T3-L1 adipocyte development

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faseb.onlinelibrary.wiley.com/doi/full/10.1096/fj.202100381RR
Apr 2023
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Differential and substrate-specific inhibition of γ-secretase by the C-terminal region of ApoE2, ApoE3, and ApoE4

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  DOI: 10.1016/j.neuron.2023.03.024
  
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sciencedirect.com/science/article/abs/pii/S0896627323002209
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Bub1 and Bub3 regulate metabolic adaptation via macrolipophagy in Drosophila

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  DOI: 10.1016/j.celrep.2023.112343
  
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sciencedirect.com/science/article/pii/S2211124723003546
Mar 2023
www.nature.com www.nature.com

Antimicrobial protein REG3A regulates glucose homeostasis and insulin resistance in obese diabetic mice

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  DOI: 10.1038/s42003-023-04616-5
  
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nature.com/articles/s42003-023-04616-5
Jan 2023
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The selective autophagy adaptor p62/SQSTM1 forms phase condensates regulated by HSP27 that facilitate the clearance of damaged lysosomes via lysophagy

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  DOI: 10.1016/j.celrep.2023.112037
  
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Intersection of immune and oncometabolic pathways drives cancer hyperprogression during immunotherapy

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  DOI: 10.1016/j.ccell.2022.12.008
  
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Transcriptomic profiling reveals sex-specific molecular signatures of adipose endothelial cells under obesogenic conditions

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  DOI: 10.1016/j.isci.2022.105811
  
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sciencedirect.com/science/article/pii/S2589004222020843
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NLRP3 activation contributes to endothelin‐1‐induced erectile dysfunction

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  DOI: 10.1111/jcmm.17463
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9806301/
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Diverse effector and regulatory functions of fibro/adipogenic progenitors during skeletal muscle fibrosis in muscular dystrophy

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  DOI: 10.1016/j.isci.2022.105775
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9804115/
Dec 2022
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Blocking AMPK β1 myristoylation enhances AMPK activity and protects mice from high-fat diet-induced obesity and hepatic steatosis

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AKTIP loss is enriched in ERα-positive breast cancer for tumorigenesis and confers endocrine resistance

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Cross-talk between TSC2 and the extracellular matrix controls pulmonary vascular proliferation and pulmonary hypertension

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Identification of phosphorylation site on PARP1 mediating its cytosolic translocation in virus-infected HeLa cells

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Glycosphingolipids are mediators of cancer plasticity through independent signaling pathways

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Methionine oxidation activates pyruvate kinase M2 to promote pancreatic cancer metastasis

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Identification of metabolic pathways underlying FGF1 and CHIR99021-mediated cardioprotection

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C/EBPδ-induced epigenetic changes control the dynamic gene transcription of S100a8 and S100a9

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Cytoplasmic PARP1 links the genome instability to the inhibition of antiviral immunity through PARylating cGAS

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NMDA receptor-dependent prostaglandin-endoperoxide synthase 2 induction in neurons promotes glial proliferation during brain development and injury

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Isoform- and cell-state-specific lipidation of ApoE in astrocytes

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Gain of function of Malate Dehydrogenase 2 (MDH2) and familial hyperglycemia

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Nov 2021
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ajplung.00323.2020-html.html

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Identification of long-lived proteins in the mitochondria reveals increased stability of the electron transport chain

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Site-specific N-glycosylation of integrin α2 mediates collagen-dependent cell survival

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Loss of nuclear DNA ligase III reverts PARP inhibitor resistance in BRCA1/53BP1 double-deficient cells by exposing ssDNA gaps

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The Coagulation and Immune Systems Are Directly Linked through the Activation of Interleukin-1α by Thrombin

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PI3K inhibitors protect against glucocorticoid-induced skin atrophy

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Brown Adipose Tissue Controls Skeletal Muscle Function via the Secretion of Myostatin

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Lin28 paralogs regulate lung branching morphogenesis

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Pancreatic fat cells of humans with type 2 diabetes display reduced adipogenic and lipolytic activity | American Journal of Physiology-Cell Physiology

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Pancreatic fat cells of humans with type 2 diabetes display reduced adipogenic and lipolytic activity

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A spatial vascular transcriptomic, proteomic, and phosphoproteomic atlas unveils an angiocrine Tie–Wnt signaling axis in the liver

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Antineoplastic effect of a diphtheria toxin-based nanoparticle targeting acute myeloid leukemia cells overexpressing CXCR4

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Mitochondrial metabolism supports resistance to IDH mutant inhibitors in acute myeloid leukemia

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Mar 2021
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Modeling the complete kinetics of coxsackievirus B3 reveals human determinants of host-cell feedback

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Synthesis and use of an amphiphilic dendrimer for siRNA delivery into primary immune cells

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Tetracycline Antibiotics Induce Host-Dependent Disease Tolerance to Infection

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Collagen-rich omentum is a premetastatic niche for integrin α2-mediated peritoneal metastasis

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p53 Integrates Temporal WDR5 Inputs during Neuroectoderm and Mesoderm Differentiation of Mouse Embryonic Stem Cells

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Decidual NK Cells Transfer Granulysin to Selectively Kill Bacteria in Trophoblasts

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Simvastatin protects photoreceptors from oxidative stress induced by all‐trans‐retinal, through the up‐regulation of interphotoreceptor retinoid binding protein

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The antibiotic bedaquiline activates host macrophage innate immune resistance to bacterial infection

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The Mammalian Cap-Specific m6Am RNA Methyltransferase PCIF1 Regulates Transcript Levels in Mouse Tissues

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Regulation of Hippocampal Memory by mTORC1 in Somatostatin Interneurons

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Neurofibromin Is an Estrogen Receptor-α Transcriptional Co-repressor in Breast Cancer

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  RRID:AB_2288042
  
  DOI: 10.1016/j.ccell.2020.02.003
  
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BRCA1 Mutational Complementation Induces Synthetic Viability

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  DOI: 10.1016/j.molcel.2020.04.006
  
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Inhibition of the Lysophosphatidylinositol Transporter ABCC1 Reduces Prostate Cancer Cell Growth and Sensitizes to Chemotherapy

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1. scibot 03 Sep 2020
  
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  ⍺/β tubulin
  
  DOI: 10.3390/cancers12082022
  
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mdpi.com/2072-6694/12/8/2022
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The X-Linked DDX3X RNA Helicase Dictates Translation Reprogramming and Metastasis in Melanoma

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  DOI: 10.1016/j.celrep.2019.05.069
  
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eIF4A supports an oncogenic translation program in pancreatic ductal adenocarcinoma

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  DOI: 10.1038/s41467-019-13086-5
  
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nature.com/articles/s41467-019-13086-5
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Human macular Müller cells rely more on serine biosynthesis to combat oxidative stress than those from the periphery

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  DOI: 10.7554/eLife.43598
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6533082/
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Liver-Type Glutaminase GLS2 Is a Druggable Metabolic Node in Luminal-Subtype Breast Cancer

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1. scibot 13 Jan 2020
  
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  RRID:AB_2288042
  
  DOI: 10.1016/j.celrep.2019.08.076
  
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Untitled document

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  DOI: 10.1016/j.immuni.2019.03.003
  
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R-DeeP: Proteome-wide and Quantitative Identification of RNA-Dependent Proteins by Density Gradient Ultracentrifugation

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  RRID:AB_2288042
  
  DOI: 10.1016/j.molcel.2019.04.018
  
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BRCA1 Mutation-Specific Responses to 53BP1 Loss-Induced Homologous Recombination and PARP Inhibitor Resistance

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Targeting Epigenetic Crosstalk as a Therapeutic Strategy for EZH2-Aberrant Solid Tumors

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cell.com/cell/fulltext/S0092-8674(18)31119-X
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Catch-Up Growth in Zebrafish Embryo Requires Neural Crest Cells Sustained by Irs1 Signaling

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Disruption of De Novo Serine Synthesis in Müller Cells Induced Mitochondrial Dysfunction and Aggravated Oxidative Damage

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Cell-Cycle Proteins Control Production of Neutrophil Extracellular Traps

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sciencedirect.com/science/article/pii/S1534580717308262
Nov 2017
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An Oxidative Central Metabolism Enables Salmonella to Utilize Microbiota-Derived Succinate

1
1. scibot 08 Nov 2017
  
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  Cell Signaling TechnologyCat# 2148S
  
  Curator: @Jmenke
  
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sciencedirect.com/science/article/pii/S1931312817303013
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Farnesoid X Receptor Regulation of the NLRP3 Inflammasome Underlies Cholestasis-Associated Sepsis

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1. scibot 08 Nov 2017
  
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  2148
  
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sciencedirect.com/science/article/pii/S1550413117301584

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