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63 Matching Annotations

Jul 2026
www.sciencedirect.com www.sciencedirect.com

Alzheimer’s disease-related mutations in APP influence colorectal tumor formation in a sex-dependent manner

1
1. scibot 04 Jul 2026
  
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  RRID:AB_2289606
  
  DOI: 10.1016/j.isci.2026.116645
  
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sciencedirect.com/science/article/pii/S2589004226020213
Jun 2026
54.241.53.176 54.241.53.176

2026.06.11.731622.full-html.html

1
1. scibot 19 Jun 2026
  
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  AB_2289606
  
  DOI: 10.64898/2026.06.11.731622
  
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54.241.53.176/8d7f4731ef399bf10aa3acd5cab5e9992b8ae24d/2026.06.11.731622.full-html.html
May 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

APP family in inhibitory neurons controls inhibitory recruitment and short-term plasticity in the hippocampus

1
1. scibot 09 May 2026
  
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  RRID:AB_2289606
  
  DOI: 10.1186/s13041-026-01296-0
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13151265/
Feb 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Immunohistochemical labeling of ongoing axonal degeneration 10 days following cervical contusion spinal cord injury in the rat

1
1. scibot 04 Feb 2026
  
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  RRID:AB_2289606
  
  DOI: 10.1038/s41393-024-01053-x
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11849397/
Dec 2025
www.sciencedirect.com:5037 www.sciencedirect.com:5037

circATF6 triggers calcium overload to synergize with EGFR-TKI in non-small cell lung cancer via modulation of proteostasis

1
1. scibot 09 Dec 2025
  
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  AB_2289606
  
  DOI: 10.1016/j.celrep.2025.116659
  
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sciencedirect.com:5037/science/article/pii/S2211124725014317
link.springer.com link.springer.com

APLP1 Interacts with SARM1 and Regulates Axonal Maintenance and Post-Injury Degeneration

1
1. scibot 06 Dec 2025
  
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  RRID:AB_2289606
  
  DOI: 10.1007/s12035-025-05408-0
  
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link.springer.com/article/10.1007/s12035-025-05408-0
www.sciencedirect.com:5037 www.sciencedirect.com:5037

Extracellular vesicles from obese visceral adipose promote pancreatic cancer development and resistance to immune checkpoint blockade therapy

1
1. scibot 03 Dec 2025
  
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  DOI: 10.1016/j.cmet.2025.10.015
  
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sciencedirect.com:5037/science/article/pii/S1550413125004759
Oct 2025
www.sciencedirect.com www.sciencedirect.com

BST2 expression at astrocyte borders promotes microglial recruitment via the C3/C3aR signaling

1
1. scibot 28 Oct 2025
  
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  DOI: 10.1016/j.neuron.2025.09.038
  
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sciencedirect.com/science/article/pii/S0896627325007512
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STBD1 mediates the crosstalk between glycogen and lipid droplets in clear cell renal cell carcinoma

1
1. scibot 18 Oct 2025
  
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  DOI: 10.1016/j.celrep.2025.116429
  
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sciencedirect.com/science/article/pii/S2211124725012008
pubs.acs.org pubs.acs.org

Multicompartment Quantitative Proteomics Revealing Potential Mechanisms Underlying the Treatment Effects of Mesenchymal-Derived Extracellular Vesicles in a Monkey Model of Cortical Injury

1
1. scibot 04 Oct 2025
  
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  DOI: 10.1021/acs.jproteome.5c00521
  
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pubs.acs.org/doi/10.1021/acs.jproteome.5c00521
Sep 2025
52.53.155.43 52.53.155.43

2025.09.07.674780v1.full-html.html

1
1. scibot 18 Sep 2025
  
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  AB_2289606
  
  DOI: 10.1101/2025.09.07.674780
  
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52.53.155.43/38cf75af3fb71fb2f93a59bfc675836bd9b1fb78/2025.09.07.674780v1.full-html.html
Aug 2025
52.53.155.43 52.53.155.43

2025.07.28.667160v1.full-html.html

1
1. scibot 05 Aug 2025
  
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  AB_2289606
  
  DOI: 10.1101/2025.07.28.667160
  
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52.53.155.43/969a14b205ba775788b5b53d9d63a84942cc91b4/2025.07.28.667160v1.full-html.html
May 2025
www.sciencedirect.com www.sciencedirect.com

Amyloid-β induces lipid droplet-mediated microglial dysfunction via the enzyme DGAT2 in Alzheimer’s disease

1
1. scibot 20 May 2025
  
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  RRID:AB_2289606
  
  DOI: 10.1016/j.immuni.2025.04.029
  
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sciencedirect.com/science/article/pii/S107476132500192X
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Engineering ARMMs for improved intracellular delivery of CRISPR-Cas9

1
1. scibot 19 May 2025
  
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  RRID:AB_2289606
  
  DOI: 10.1016/j.vesic.2025.100082
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12245188/
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Microglial TMEM119 binds to amyloid-β to promote its clearance in an Aβ-depositing mouse model of Alzheimer’s disease

1
1. scibot 17 May 2025
  
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  RRID:AB_2289606
  
  DOI: 10.1016/j.immuni.2025.04.018
  
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sciencedirect.com/science/article/pii/S1074761325001815
Apr 2025
elifesciences.org elifesciences.org

APP β-CTF triggers cell-autonomous synaptic toxicity independent of Aβ

1
1. scibot 24 Apr 2025
  
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  RRID:AB_2289606
  
  DOI: 10.7554/eLife.100968
  
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elifesciences.org/articles/100968
Dec 2024
www.science.org www.science.org

ProNGF elicits retrograde axonal degeneration of basal forebrain neurons through p75NTR and induction of amyloid precursor protein

2
1. scibot 20 Dec 2024
  
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  AB_2289606
  
  DOI: 10.1126/scisignal.adn2616
  
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2. scibot 20 Dec 2024
  
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  AB_32136
  
  DOI: 10.1126/scisignal.adn2616
  
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  Curator: @inessasarian
  
  SciCrunch record: RRID:AB_2289606
  
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  RRIDCUR:Unresolved RRID:AB_2289606
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science.org/doi/10.1126/scisignal.adn2616
Nov 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Hub genes and key pathways of traumatic brain injury:... : Neural Regeneration Research

1
1. scibot 07 Nov 2024
  
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  RRID:AB_2289606
  
  DOI: 10.4103/NRR.NRR-D-23-01633
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11826463/
52.53.155.43 52.53.155.43

enhanced_autophagic_clearance_of_amyloid___via.25-html.html

1
1. scibot 07 Nov 2024
  
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  AB_2289606
  
  DOI: 10.4103/nrr.nrr-d-23-01633
  
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52.53.155.43/f837a450e4d673727102c6a319547882bc299234/enhanced_autophagic_clearance_of_amyloid___via.25-html.html
Aug 2024
www.sciencedirect.com www.sciencedirect.com

Rapid phagosome isolation enables unbiased multiomic analysis of human microglial phagosomes

1
1. scibot 22 Aug 2024
  
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  AB_2289606
  
  DOI: 10.1016/j.immuni.2024.07.019
  
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sciencedirect.com/science/article/pii/S1074761324003686
Jul 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Alzheimer’s disease linked Aβ42 exerts product feedback inhibition on γ-secretase impairing downstream cell signaling

1
1. scibot 23 Jul 2024
  
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  RRID:AB_2289606
  
  DOI: 10.7554/eLife.90690
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11259434/
May 2024
www.mdpi.com www.mdpi.com

Transcranial Magneto-Acoustic Stimulation Protects Synaptic Rehabilitation from Amyloid-Beta Plaques via Regulation of Microglial Functions

1
1. scibot 03 May 2024
  
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  RRID:AB_2289606
  
  DOI: 10.3390/ijms25094651
  
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mdpi.com/1422-0067/25/9/4651
Oct 2023
www.sciencedirect.com www.sciencedirect.com

Toll-like receptor 4 and CD11b expressed on microglia coordinate eradication of Candida albicans cerebral mycosis

1
1. scibot 28 Oct 2023
  
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  RRID:AB_2289606
  
  DOI: 10.1016/j.celrep.2023.113240
  
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sciencedirect.com/science/article/pii/S2211124723012524
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Visualizing Wallerian degeneration in the corticospinal tract after sensorimotor cortex ischemia in mice

1
1. scibot 20 Oct 2023
  
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  RRID:AB_2289606
  
  DOI: 10.4103/1673-5374.380903
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10581571/
Sep 2023
onlinelibrary.wiley.com onlinelibrary.wiley.com

Plk2 promotes synaptic destabilization through disruption of N-cadherin adhesion complexes during homeostatic adaptation to hyperexcitation

1
1. scibot 06 Sep 2023
  
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  RRID:AB_2289606
  
  DOI: 10.1111/jnc.15948
  
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onlinelibrary.wiley.com/doi/10.1111/jnc.15948
Aug 2023
www.sciencedirect.com www.sciencedirect.com

Neuronal γ-secretase regulates lipid metabolism, linking cholesterol to synaptic dysfunction in Alzheimer’s disease

1
1. scibot 05 Aug 2023
  
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  RRID:AB_2289606
  
  DOI: 10.1016/j.neuron.2023.07.005
  
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sciencedirect.com/science/article/pii/S0896627323005135
Jul 2023
www.sciencedirect.com www.sciencedirect.com

Evidence for a clathrin-independent endocytic pathway for APP internalization in the neuronal somatodendritic compartment

1
1. scibot 13 Jul 2023
  
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  RRID:AB_2289606
  
  DOI: 10.1016/j.celrep.2023.112774
  
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sciencedirect.com/science/article/pii/S2211124723007854
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Hepatic soluble epoxide hydrolase activity regulates cerebral Aβ metabolism and the pathogenesis of Alzheimer’s disease in mice

1
1. scibot 06 Jul 2023
  
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  RRID:AB_2289606
  
  DOI: 10.1016/j.neuron.2023.06.002
  
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sciencedirect.com/science/article/pii/S0896627323004373
Jun 2023
www.sciencedirect.com www.sciencedirect.com

ArhGAP11A mediates amyloid-β generation and neuropathology in an Alzheimer’s disease-like mouse model

1
1. scibot 16 Jun 2023
  
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  RRID:AB_2289606
  
  DOI: 10.1016/j.celrep.2023.112624
  
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sciencedirect.com/science/article/pii/S2211124723006356
Apr 2023
www.sciencedirect.com www.sciencedirect.com

Differential and substrate-specific inhibition of γ-secretase by the C-terminal region of ApoE2, ApoE3, and ApoE4

1
1. scibot 12 Apr 2023
  
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  RRID:AB_2289606
  
  DOI: 10.1016/j.neuron.2023.03.024
  
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sciencedirect.com/science/article/abs/pii/S0896627323002209
Mar 2023
journals.lww.com journals.lww.com

Inhibiting 5-hydroxytryptamine receptor 3 alleviates... : Neural Regeneration Research

1
1. scibot 11 Mar 2023
  
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  RRID:AB_2289606
  
  DOI: 10.4103/1673-5374.366492
  
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journals.lww.com/nrronline/Fulltext/2023/09000/Inhibiting_5_hydroxytryptamine_receptor_3.30.aspx
Oct 2022
www.sciencedirect.com www.sciencedirect.com

SYK coordinates neuroprotective microglial responses in neurodegenerative disease

1
1. scibot 20 Oct 2022
  
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  RRID:AB_2289606
  
  DOI: 10.1016/j.cell.2022.09.030
  
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sciencedirect.com/science/article/pii/S0092867422012491
Sep 2022
www.sciencedirect.com www.sciencedirect.com

Molecular convergence between Down syndrome and fragile X syndrome identified using human pluripotent stem cell models

1
1. scibot 08 Sep 2022
  
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  RRID:AB_2289606
  
  DOI: 10.1016/j.celrep.2022.111312
  
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sciencedirect.com/science/article/pii/S2211124722011366
Aug 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Induction of A Disintegrin and Metalloproteinase with Thrombospondin motifs 1 by a rare variant or cognitive activities reduces hippocampal amyloid-β and consequent Alzheimer’s disease risk

1
1. scibot 26 Aug 2022
  
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  RRID:AB_2289606
  
  DOI: 10.3389/fnagi.2022.896522
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9395645/
Jul 2022
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Inhibition of SIRT2 promotes APP acetylation and ameliorates cognitive impairment in APP/PS1 transgenic mice

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Jun 2022
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Icariin ameliorates memory deficits through regulating... : Neural Regeneration Research

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BPS Publications

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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15836
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The neuronal retromer can regulate both neuronal and microglial phenotypes of Alzheimer's disease

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Nov 2021
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Transcriptomic taxonomy and neurogenic trajectories of adult human, macaque, and pig hippocampal and entorhinal cells

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Aug 2021
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Untitled document

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Increased P2×2 receptors induced by amyloid-β peptide participates in the neurotoxicity in alzheimer’s disease

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sciencedirect.com/science/article/pii/S0753332221007502
Jul 2021
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Who's in, who's out? Re-evaluation of lipid raft residents

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onlinelibrary.wiley.com/doi/10.1111/jnc.15446
Jun 2021
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Antisense Oligonucleotide-Induced Amyloid Precursor Protein Splicing Modulation as a Therapeutic Approach for Dutch-Type Cerebral Amyloid Angiopathy

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liebertpub.com/doi/abs/10.1089/nat.2021.0005
Mar 2021
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Ketogenic diet protects myelin and axons in diffuse axonal injury

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tandfonline.com/doi/full/10.1080/1028415X.2021.1875300
Feb 2021
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Mitochondrial fission is a critical modulator of mutant APP-induced neural toxicity

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The cellular expression and proteolytic processing of the amyloid precursor protein is independent of TDP-43

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portlandpress.com/bioscirep/article/40/4/BSR20200435/222674/The-cellular-expression-and-proteolytic-processing
Jan 2021
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Small Molecule SARM1 Inhibitors Recapitulate the SARM1−/− Phenotype and Allow Recovery of a Metastable Pool of Axons Fated to Degenerate

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sciencedirect.com/science/article/pii/S2211124720315771
Dec 2020
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APP Family Regulates Neuronal Excitability and Synaptic Plasticity but Not Neuronal Survival

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cell.com/neuron/abstract/S0896-6273(20)30642-5
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Pulse-Chase Proteomics of the App Knockin Mouse Models of Alzheimer’s Disease Reveals that Synaptic Dysfunction Originates in Presynaptic Terminals

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Cell-autonomous role of Presenilin in age-dependent survival of cortical interneurons

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Sep 2020
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Depletion of the AD Risk Gene SORL1 Selectively Impairs Neuronal Endosomal Traffic Independent of Amyloidogenic APP Processing

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sciencedirect.com/science/article/pii/S2211124720306963
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Detection of Deleterious On-Target Effects after HDR-Mediated CRISPR Editing

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  DOI: 10.1016/j.celrep.2020.107689
  
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Microglia Dysfunction Caused by the Loss of Rhoa Disrupts Neuronal Physiology and Leads to Neurodegeneration

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Necrostatin‐1 prevents the proapoptotic protein Bcl‐2/adenovirus E1B 19‐kDa interacting protein 3 from integration into mitochondria

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onlinelibrary.wiley.com/doi/10.1111/jnc.14993
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Increased levels of Stress-inducible phosphoprotein-1 accelerates amyloid-β deposition in a mouse model of Alzheimer’s disease

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  DOI: 10.1186/s40478-020-01013-5
  
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BPS Publications

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  APP
  
  DOI: 10.1111/bph.15131
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15131
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Sodium butyrate inhibits high cholesterol-induced neuronal amyloidogenesis by modulating NRF2 stabilization-mediated ROS levels: involvement of NOX2 and SOD1

1
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  DOI: 10.1038/s41419-020-2663-1
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7303181/
Aug 2020
elifesciences.org elifesciences.org

Opposite changes in APP processing and human Aβ levels in rats carrying either a protective or a pathogenic APP mutation

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  DOI: 10.7554/eLife.52612
  
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elifesciences.org/articles/52612
Jan 2020
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Chronic cerebral hypoperfusion shifts the equilibrium of amyloid β oligomers to aggregation-prone species with higher molecular weight

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  DOI: 10.1038/s41598-019-39494-7
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6391466/
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Untitled document

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  DOI: 10.1523/JNEUROSCI.1280-17.2018
  
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jneurosci.org/content/38/18/4288
Nov 2018
onlinelibrary.wiley.com onlinelibrary.wiley.com

The conformational epitope for a new Aβ42 protofibril‐selective antibody partially overlaps with the peptide N‐terminal region

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onlinelibrary.wiley.com/doi/10.1111/jnc.14211/full

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