255 Matching Annotations
  1. Jun 2024
  2. journals.plos.org journals.plos.org
    Myosin II mediates Shh signals to shape dental epithelia via control of cell adhesion and movement
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    1. scibot 22 Jun 2024
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      DOI: 10.1371/journal.pgen.1011326

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    journals.plos.org/plosgenetics/article
  3. www.sciencedirect.com www.sciencedirect.com
    Demethylase FTO-mediated m6A modification of SIK1 modulates placental cytotrophoblast syncytialization in type 2 diabetes mellitus.
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    1. scibot 08 Jun 2024
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    sciencedirect.com/science/article/pii/S2589004224011222
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DDX56 promotes EMT and cancer stemness via MELK-FOXM1 axis in hepatocellular carcinoma
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    1. scibot 08 Jun 2024
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      DOI: 10.1016/j.isci.2024.109827

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    ncbi.nlm.nih.gov/pmc/articles/PMC11141150/
  5. 52.53.155.43 52.53.155.43
    Secretion of WNT7A by UC-MSCs assist in promoting the endometrial epithelial regeneration
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    1. scibot 08 Jun 2024
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      DOI: 10.1016/j.isci.2024.109888

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    52.53.155.43/cced30d2a74f6a0a443c073a769617b5ff3774c6/1-s2.0-S2589004224011106-main-html.html
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Exocyst Complex is Required for the Trafficking and Delivery of KCa3.1 to the Basolateral Membrane of Polarized Epithelia
    1
    1. scibot 07 Jun 2024
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      DOI: 10.1152/ajpcell.00374.2022

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    ncbi.nlm.nih.gov/pmc/articles/PMC10243536/
  7. Local file Local file
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    1. scibot 06 Jun 2024
      C. Other antibodies used in the study.

      DOI: 10.1101/2022.03.30.486322

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  8. May 2024
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transcription factor activating enhancer-binding protein 2ε (AP2ε) modulates phenotypic plasticity and progression of malignant melanoma
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    1. scibot 24 May 2024
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      DOI: 10.1038/s41419-024-06733-3

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    ncbi.nlm.nih.gov/pmc/articles/PMC11109141/
  10. www.sciencedirect.com www.sciencedirect.com
    Patterning and folding of intestinal villi by active mesenchymal dewetting
    1
    1. scibot 23 May 2024
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    sciencedirect.com/science/article/pii/S0092867424004653
  11. www.sciencedirect.com www.sciencedirect.com
    Mouse neural tube organoids self-organize floorplate through BMP-mediated cluster competition
    1
    1. scibot 23 May 2024
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      DOI: 10.1016/j.devcel.2024.04.021

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    sciencedirect.com/science/article/pii/S1534580724002971
  12. journals.biologists.com journals.biologists.com
    FGF signaling regulates salivary gland branching morphogenesis by modulating cell adhesion
    1
    1. scibot 22 May 2024
      CST, 3195S

      DOI: 10.1242/dev.201293

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    journals.biologists.com/dev/article/150/6/dev201293/297264/FGF-signaling-regulates-salivary-gland-branching
  13. www.sciencedirect.com www.sciencedirect.com
    The Janus kinase 1 is critical for pancreatic cancer initiation and progression
    1
    1. scibot 14 May 2024
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      DOI: 10.1016/j.celrep.2024.114202

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    sciencedirect.com/science/article/pii/S2211124724005308
  14. www.sciencedirect.com www.sciencedirect.com
    Tracking in situ checkpoint inhibitor-bound target T cells in patients with checkpoint-induced colitis
    1
    1. scibot 14 May 2024
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    sciencedirect.com/science/article/pii/S153561082400134X
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    Long-term expandable mouse and human-induced nephron progenitor cells enable kidney organoid maturation and modeling of plasticity and disease
    2
    1. scibot 01 May 2024
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      DOI: 10.1016/j.stem.2024.04.002

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      DOI: 10.1016/j.stem.2024.04.002

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    sciencedirect.com/science/article/pii/S1934590924001292
  16. Apr 2024
  17. www.sciencedirect.com www.sciencedirect.com
    Intraepithelial mast cells drive gasdermin C-mediated type 2 immunity
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    1. scibot 16 Apr 2024
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      DOI: 10.1016/j.immuni.2024.03.017

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      DOI: 10.1016/j.immuni.2024.03.017

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    sciencedirect.com/science/article/pii/S1074761324001389
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    Insulin receptor signaling engages bladder urothelial defenses that limit urinary tract infection
    1
    1. scibot 11 Apr 2024
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      DOI: 10.1016/j.celrep.2024.114007

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    sciencedirect.com/science/article/pii/S2211124724003358
  19. www.sciencedirect.com www.sciencedirect.com
    Pharmacological induction of chromatin remodeling drives chemosensitization in triple-negative breast cancer
    1
    1. scibot 09 Apr 2024
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      DOI: 10.1016/j.xcrm.2024.101504

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    sciencedirect.com/science/article/pii/S2666379124001733
  20. 52.53.155.43 52.53.155.43
    Mechanical strengthening of cell-cell adhesion during mouse embryo compaction
    1
    1. scibot 05 Apr 2024
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    52.53.155.43/870c1a0ff31c21208e246618afb62f0f1069de5c/1-s2.0-S000634952400208X-main-html.html
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    Tumor cell-intrinsic epigenetic dysregulation shapes cancer-associated fibroblasts heterogeneity to metabolically support pancreatic cancer
    1
    1. scibot 05 Apr 2024
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      DOI: 10.1016/j.ccell.2024.03.005

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    sciencedirect.com/science/article/pii/S1535610824000904
  22. www.sciencedirect.com www.sciencedirect.com
    Vangl-dependent mesenchymal thinning shapes the distal lung during murine sacculation
    1
    1. scibot 04 Apr 2024
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    sciencedirect.com/science/article/pii/S1534580724001783
  23. www.sciencedirect.com www.sciencedirect.com
    Telomere dysfunction alters intestinal stem cell dynamics to promote cancer
    1
    1. scibot 04 Apr 2024
      RRID:AB_2291471

      DOI: 10.1016/j.devcel.2024.03.020

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    sciencedirect.com/science/article/pii/S1534580724001886
  24. www.sciencedirect.com www.sciencedirect.com
    Defining the contribution of Troy-positive progenitor cells to the mouse esophageal epithelium
    2
    1. scibot 02 Apr 2024
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      DOI: 10.1016/j.devcel.2024.03.011

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    sciencedirect.com/science/article/pii/S1534580724001795
  25. Mar 2024
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Histone H3.1 is a chromatin-embedded redox sensor triggered by tumor cells developing adaptive phenotypic plasticity and multidrug resistance
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    1. scibot 19 Mar 2024
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      DOI: 10.1016/j.celrep.2024.113897

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    ncbi.nlm.nih.gov/pmc/articles/PMC11209755/
  27. Feb 2024
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Depletion of PHLDB2 Suppresses Epithelial–Mesenchymal Transition and Enhances Anti-Tumor Immunity in Head and Neck Squamous Cell Carcinoma
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    1. scibot 28 Feb 2024
      RRID:AB_2291471

      DOI: 10.3390/biom14020232

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    ncbi.nlm.nih.gov/pmc/articles/PMC10886581/
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hypoxia at 3D organoid establishment selects essential subclones within heterogenous pancreatic cancer
    1
    1. scibot 23 Feb 2024
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      DOI: 10.3389/fcell.2024.1327772

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    ncbi.nlm.nih.gov/pmc/articles/PMC10875002/
  30. www-cell-com.ezproxy.auckland.ac.nz www-cell-com.ezproxy.auckland.ac.nz
    Single-cell assessment of primary and stem cell-derived human trophoblast organoids as placenta-modeling platforms
    1
    1. scibot 15 Feb 2024
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      DOI: 10.1016/j.devcel.2024.01.023

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    www-cell-com.ezproxy.auckland.ac.nz/developmental-cell/fulltext/S1534580724000431
  31. www.sciencedirect.com www.sciencedirect.com
    The GATOR2 complex maintains lysosomal-autophagic function by inhibiting the protein degradation of MiT/TFEs
    1
    1. scibot 08 Feb 2024
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      DOI: 10.1016/j.molcel.2024.01.012

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    sciencedirect.com/science/article/pii/S1097276524000480
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    OVOL2 induces autophagy-mediated epithelial-mesenchymal transition by the ERK1/2 MAPK signaling in lung adenocarcinoma
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      DOI: 10.1016/j.isci.2024.108873

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    ncbi.nlm.nih.gov/pmc/articles/PMC10838806/
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Nephron progenitors rhythmically alternate between renewal and differentiation phases that synchronize with kidney branching morphogenesis
    1
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      DOI: 10.1101/2023.11.21.568157

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    ncbi.nlm.nih.gov/pmc/articles/PMC10690271/
  34. Jan 2024
  35. www.sciencedirect.com www.sciencedirect.com
    Spatiotemporal role of SETD2-H3K36me3 in murine pancreatic organogenesis
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    sciencedirect.com/science/article/pii/S2211124724000317
  36. www.science.org www.science.org
    RHOAL57V drives the development of diffuse gastric cancer through IGF1R-PAK1-YAP1 signaling
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      DOI: 10.1126/scisignal.adg5289

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    science.org/doi/10.1126/scisignal.adg5289
  37. www.sciencedirect.com www.sciencedirect.com
    ERK-mediated curvature feedback regulates branching morphogenesis in lung epithelial tissue
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      DOI: 10.1016/j.cub.2023.12.049

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    sciencedirect.com/science/article/pii/S0960982223017499
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Gasdermin-D promotes hyperuricemia-induced renal tubular injury through RIG-I/caspase-1 pathway
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    ncbi.nlm.nih.gov/pmc/articles/PMC10767184/
  39. Dec 2023
  40. www.sciencedirect.com www.sciencedirect.com
    A desmosomal cadherin controls multipotent hair follicle stem cell quiescence and orchestrates regeneration through adhesion signaling
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    sciencedirect.com/science/article/pii/S2589004223026457
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    Oncogenic KRAS effector USP13 promotes metastasis in non-small cell lung cancer through deubiquitinating β-catenin
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    sciencedirect.com/science/article/pii/S2211124723015231
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A novel patient-derived meningioma spheroid model as a tool to study and treat epithelial-to-mesenchymal transition (EMT) in meningiomas
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      DOI: 10.1186/s40478-023-01677-9

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    ncbi.nlm.nih.gov/pmc/articles/PMC10725030/
  43. www.sciencedirect.com www.sciencedirect.com
    Sphingolipid paracrine signaling impairs keratinocyte adhesion to promote melanoma invasion
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      DOI: 10.1016/j.celrep.2023.113586

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    sciencedirect.com/science/article/pii/S221112472301598X
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    Heterogeneity and transcriptional drivers of triple-negative breast cancer
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    sciencedirect.com/science/article/pii/S2211124723015760
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    Integrated multi-omics profiling to dissect the spatiotemporal evolution of metastatic hepatocellular carcinoma
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    Evolutionary states and trajectories characterized by distinct pathways stratify patients with ovarian high grade serous carcinoma
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    Independent control over cell patterning and adhesion on hydrogel substrates for tissue interface mechanobiology
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    KS10076, a chelator for redox-active metal ions, induces ROS-mediated STAT3 degradation in autophagic cell death and eliminates ALDH1+ stem cells
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    Snail acetylation by autophagy-derived acetyl-coenzyme A promotes invasion and metastasis of KRAS-LKB1 co-mutated lung cancer cells
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    A junction-dependent mechanism drives murine mammary cell intercalation for ductal elongation
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    Loss of E-cadherin Induces IGF1R Activation and Reveals a Targetable Pathway in Invasive Lobular Breast Carcinoma
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  94. Feb 2023
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    TGF-β in the microenvironment induces a physiologically occurring immune-suppressive senescent state
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    IGF-binding proteins secreted by cancer-associated fibroblasts induce context-dependent drug sensitization of lung cancer cells
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    Generating human blastoids modeling blastocyst-stage embryos and implantation
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    CD70 is a therapeutic target upregulated in EMT-associated EGFR tyrosine kinase inhibitor resistance
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    Goji berry (Lycium barbarum) inhibits the proliferation, adhesion, and migration of oral cancer cells by inhibiting the ERK, AKT, and CyclinD cell signaling pathways: an in-vitro study
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    Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity
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    RNA exosome ribonuclease DIS3 degrades Pou6f1 to promote mouse pre-implantation cell differentiation
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  102. Jan 2023
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    A DLG1-ARHGAP31-CDC42 axis is essential for the intestinal stem cell response to fluctuating niche Wnt signaling
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    Identification of Genes Associated with Liver Metastasis in Pancreatic Cancer Reveals PCSK6 as a Crucial Mediator
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  105. Dec 2022
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    ΔNp63/p73 drive metastatic colonization by controlling a regenerative epithelial stem cell program in quasi-mesenchymal cancer stem cells
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    The mitochondrial UPR regulator ATF5 promotes intestinal barrier function via control of the satiety response
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    Negative E-cadherin expression on bone marrow myeloma cell membranes is associated with extramedullary disease
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  110. Nov 2022
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    CRABP2 is associated with thyroid cancer recurrence and promotes invasion via the integrin/FAK/AKT pathway
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    Re-purposing the pro-senescence properties of doxorubicin to introduce immunotherapy in breast cancer brain metastasis
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  113. Oct 2022
  114. www.nature.com www.nature.com
    The Cancermuts software package for the prioritization of missense cancer variants: a case study of AMBRA1 in melanoma
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  115. Sep 2022
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    The molecular network of the proteasome machinery inhibition response is orchestrated by HSP70, revealing vulnerabilities in cancer cells
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    Pulmonary neuroendocrine cells sense succinate to stimulate myoepithelial cell contraction
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    Modeling human extraembryonic mesoderm cells using naive pluripotent stem cells
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  119. Aug 2022
  120. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Novel ER Stress Mediator TMTC3 Promotes Squamous Cell Carcinoma Progression by Activating GRP78/PERK Signaling Pathway
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    A WISP1 antibody inhibits MRTF signaling to prevent the progression of established liver fibrosis
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    Glycosphingolipids are mediators of cancer plasticity through independent signaling pathways
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  123. Jul 2022
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    Decoding the activated stem cell phenotype of the neonatally maturing pituitary
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    Efficacy of Combined Use of Everolimus and Second-Generation Pan-EGRF Inhibitors in KRAS Mutant Non-Small Cell Lung Cancer Cell Lines
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    Tumorigenic cell selection and substrate rigidity manipulation using 2D and 3D extracellular matrices
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    Long non-coding RNA EVADR induced by Fusobacterium nucleatum infection promotes colorectal cancer metastasis
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    Poziotinib for EGFR exon 20-mutant NSCLC: Clinical efficacy, resistance mechanisms, and impact of insertion location on drug sensitivity
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    Integrin β3 Promotes Resistance to EGFR-TKI in Non-Small-Cell Lung Cancer by Upregulating AXL through the YAP Pathway
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  130. Jun 2022
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    Organoid-derived intestinal epithelial cells are a suitable model for preclinical toxicology and pharmacokinetic studies
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    Lymphatics act as a signaling hub to regulate intestinal stem cell activity
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    Protocols for SARS-CoV-2 infection in primary ocular cells and eye organoids
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  134. May 2022
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    The developmental origin and the specification of the adrenal cortex in humans and cynomolgus monkeys
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    Stem-cell-derived trophoblast organoids model human placental development and susceptibility to emerging pathogens
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  137. Apr 2022
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    TNFɑ Antagonist in Combination with PD-1 Blocker to Prevent or Retard Malignant Transformation of B[a]P-induced Chronic Lung Inflammation
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    Gene repression through epigenetic modulation by PPARA enhances hepatocellular proliferation
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    Single-cell proteomics defines the cellular heterogeneity of localized prostate cancer
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    Quiescent cancer cells resist T cell attack by forming an immunosuppressive niche
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    Microbiota-dependent activation of the myeloid calcineurin-NFAT pathway inhibits B7H3- and B7H4-dependent anti-tumor immunity in colorectal cancer
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  143. Mar 2022
  144. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Binding blockade between TLN1 and integrin β1 represses triple-negative breast cancer
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    Peritoneal Restoration by Repurposing Vitamin D Inhibits Ovarian Cancer Dissemination via Blockade of the TGF-β1/Thrombospondin-1 Axis
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    Delicate regulation of IL-1β-mediated inflammation by cyclophilin A
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    A reversible metabolic stress-sensitive regulation of CRMP2A orchestrates EMT/stemness and increases metastatic potential in cancer
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    Protocol for serial organoid formation assay using primary colorectal cancer tissues to evaluate cancer stem cell activity
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    Crosstalk between ERK and MRTF-A signaling regulates TGFβ1-induced epithelial-mesenchymal transition
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    F1000Research Article: Negative E-cadherin expression on bone marrow myeloma cell membranes is associated with extramedullary disease.
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  151. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Patterning the embryonic pulmonary mesenchyme
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    DRAM-4 and DRAM-5 are compensatory regulators of autophagy and cell survival in nutrient-deprived conditions
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    Interferon-γ promotes monocyte-mediated lung injury during influenza infection
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    Gα13 loss in Kras/Tp53 mouse model of pancreatic tumorigenesis promotes tumors susceptible to rapamycin
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  155. Feb 2022
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    Cellular plasticity upon proton irradiation determines tumor cell radiosensitivity
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    A FBXO7/EYA2-SCFFBXW7 axis promotes AXL-mediated maintenance of mesenchymal and immune evasion phenotypes of cancer cells
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    A positive feed-forward loop between Fusobacterium nucleatum and ethanol metabolism reprogramming drives laryngeal cancer progression and metastasis
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  159. www.embopress.org www.embopress.org
    Identification of treatment-induced vulnerabilities in pancreatic cancer patients using functional model systems
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  160. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Radiation induces epithelial to mesenchymal transition via upregulation of PD-L1 in nasopharyngeal carcinoma cell
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    In vivo CRISPR screening identifies BAZ2 chromatin remodelers as druggable regulators of mammalian liver regeneration
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  162. Jan 2022
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    Molecular dynamics and functional characterization of I37R-CFTR lasso mutation provide insights into channel gating activity
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  164. Dec 2021
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    Substratum stiffness regulates Erk signaling dynamics through receptor-level control
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    Emergence and patterning dynamics of mouse-definitive endoderm
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    MATISSE: An analysis protocol for combining imaging mass cytometry with fluorescence microscopy to generate single-cell data
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    Pharmacological targeting of Sam68 functions in colorectal cancer stem cells
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    Artemisinin Mediates Its Tumor-Suppressive Activity in Hepatocellular Carcinoma Through Targeted Inhibition of FoxM1
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    A mechanistic basis for the malignant progression of salivary gland tumors
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  171. Nov 2021
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    Statins affect cancer cell plasticity with distinct consequences for tumor progression and metastasis
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    A recurrent chromosomal inversion suffices for driving escape from oncogene-induced senescence via subTAD reorganization
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    A novel jamming phase diagram links tumor invasion to non-equilibrium phase separation
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  175. Oct 2021
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    MAPK pathway activation selectively inhibits ASCL1-driven small cell lung cancer
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    Kinase DYRK2 acts as a regulator of autophagy and an indicator of favorable prognosis in gastric carcinoma
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    Proteomic and phosphoproteomic analyses identify liver-related signaling in retinal pigment epithelial cells during EMT
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    Site-specific N-glycosylation of integrin α2 mediates collagen-dependent cell survival
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    The hepatocyte growth factor/c-met pathway is a key determinant of the fibrotic kidney local microenvironment
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    Uterine epithelial LIF receptors contribute to implantation chamber formation in blastocyst attachment
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  182. Sep 2021
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    The thermogenic activity of adjacent adipocytes fuels the progression of ccRCC and compromises anti-tumor therapeutic efficacy
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    Tumor-initiating stem cell shapes its microenvironment into an immunosuppressive barrier and pro-tumorigenic niche
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    Functional diagnostics using fresh uncultured lung tumor cells to guide personalized treatments
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    The FAPα-activated prodrug Z-GP-DAVLBH inhibits the growth and pulmonary metastasis of osteosarcoma cells by suppressing the AXL pathway
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    Entosis is induced by UV radiation.
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    Anisotropic expansion of hepatocyte lumina enforced by apical bulkheads
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    Integrative analysis of the forkhead box A2 (FOXA2) cistrome for the human endometrium
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    KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance
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    Integrative analysis of the forkhead box A2 (FOXA2) cistrome for the human endometrium
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    Extracellular domain shedding of the ALK receptor mediates neuroblastoma cell migration
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    Targeted mass-spectrometry-based assays enable multiplex quantification of receptor tyrosine kinase, MAP kinase, and AKT signaling
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  206. May 2021
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    PD-L1 recruits phospholipase C and enhances tumorigenicity of lung tumors harboring mutant forms of EGFR
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    Pluripotent stem cell-derived endometrial stromal fibroblasts in a cyclic, hormone-responsive, coculture model of human decidua
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    Alveolar epithelial cell fate is maintained in a spatially restricted manner to promote lung regeneration after acute injury
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    Mechanical Tension Promotes Formation of Gastrulation-like Nodes and Patterns Mesoderm Specification in Human Embryonic Stem Cells
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    Small Extracellular Vesicle Regulation of Mitochondrial Dynamics Reprograms a Hypoxic Tumor Microenvironment
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    Pharmacoproteomics Identifies Kinase Pathways that Drive the Epithelial-Mesenchymal Transition and Drug Resistance in Hepatocellular Carcinoma
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    Quantitative chemoproteomics reveals O-GlcNAcylation of cystathionine γ-lyase (CSE) represses trophoblast syncytialization
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    RNA demethylation by FTO stabilizes the FOXJ1 mRNA for proper motile ciliogenesis
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    Alisertib inhibits migration and invasion of EGFR-TKI resistant cells by partially reversing the epithelial-mesenchymal transition
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