73 Matching Annotations
  1. May 2024
  2. www.mdpi.com www.mdpi.com
    Transcranial Magneto-Acoustic Stimulation Protects Synaptic Rehabilitation from Amyloid-Beta Plaques via Regulation of Microglial Functions
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    1. scibot 03 May 2024
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      DOI: 10.3390/ijms25094651

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    mdpi.com/1422-0067/25/9/4651
  3. Apr 2024
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Edaravone Dexborneol mitigates pathology in animal and cell culture models of Alzheimer’s disease by inhibiting neuroinflammation and neuronal necroptosis
    1
    1. scibot 30 Apr 2024
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      DOI: 10.1186/s13578-024-01230-8

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    ncbi.nlm.nih.gov/pmc/articles/PMC11056062/
  5. www.sciencedirect.com www.sciencedirect.com
    Altered GM1 catabolism affects NMDAR-mediated Ca2+ signaling at ER-PM junctions and increases synaptic spine formation in a GM1-gangliosidosis model
    1
    1. scibot 18 Apr 2024
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      DOI: 10.1016/j.celrep.2024.114117

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    sciencedirect.com/science/article/pii/S2211124724004455
  6. Mar 2024
  7. 52.53.155.43 52.53.155.43
    Translational modulator ISRIB alleviates synaptic and behavioral phenotypes in Fragile X syndrome
    2
    1. scibot 07 Mar 2024
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      DOI: 10.1016/j.isci.2024.109259

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    2. scibot 07 Mar 2024
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    52.53.155.43/1554211ff93ae48a6e5e3dc12f00513269de2f76/1-s2.0-S2589004224004802-main-html.html
  8. Feb 2024
  9. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Brief exposure to enriched environment rapidly shapes the glutamate synapses in the rat brain: A metaplastic fingerprint
    1
    1. scibot 22 Feb 2024
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      DOI: 10.1111/ejn.16279

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    onlinelibrary.wiley.com/doi/10.1111/ejn.16279
  10. content.iospress.com content.iospress.com
    Inhibition of mGluR5/PI3K-AKT Pathway Alleviates Alzheimer’s Disease-Like Pathology Through the Activation of Autophagy in 5XFAD Mice
    1
    1. scibot 16 Feb 2024
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      DOI: 10.3233/JAD-221058

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    content.iospress.com/articles/journal-of-alzheimers-disease/jad221058
  11. Jan 2024
  12. www.jneurosci.org www.jneurosci.org
    Nascent Aβ42 Fibrillization in Synaptic Endosomes Precedes Plaque Formation in a Mouse Model of Alzheimer's-like β-Amyloidosis
    1
    1. scibot 02 Jan 2024
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      DOI: 10.1523/JNEUROSCI.1318-23.2023

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  13. Dec 2023
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Developing a Toolbox of Antibodies Validated for Array Tomography-Based Imaging of Brain Synapses
    1
    1. scibot 28 Dec 2023
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      DOI: 10.1523/ENEURO.0290-23.2023

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    ncbi.nlm.nih.gov/pmc/articles/PMC10748464/
  15. www.sciencedirect.com www.sciencedirect.com
    Pre- and postsynaptic nanostructures increase in size and complexity after induction of long-term potentiation
    1
    1. scibot 23 Dec 2023
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      DOI: 10.1016/j.isci.2023.108679

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    sciencedirect.com/science/article/pii/S2589004223027566
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Developing a Toolbox of Antibodies Validated for Array Tomography-Based Imaging of Brain Synapses
    1
    1. scibot 01 Dec 2023
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      DOI: 10.1101/2023.06.28.546920

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    ncbi.nlm.nih.gov/pmc/articles/PMC10327040/
  17. Oct 2023
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Behavioral and neuropathological characterization over the adult lifespan of the human tau knock-in mouse
    1
    1. scibot 18 Oct 2023
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      DOI: 10.3389/fnagi.2023.1265151

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    ncbi.nlm.nih.gov/pmc/articles/PMC10576558/
  19. Sep 2023
  20. www.sciencedirect.com www.sciencedirect.com
    Parkinson’s disease-linked parkin mutation disrupts recycling of synaptic vesicles in human dopaminergic neurons
    1
    1. scibot 19 Sep 2023
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      DOI: 10.1016/j.neuron.2023.08.018

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    sciencedirect.com/science/article/abs/pii/S0896627323006293
  21. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Plk2 promotes synaptic destabilization through disruption of N-cadherin adhesion complexes during homeostatic adaptation to hyperexcitation
    1
    1. scibot 06 Sep 2023
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      DOI: 10.1111/jnc.15948

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    onlinelibrary.wiley.com/doi/10.1111/jnc.15948
  22. www.sciencedirect.com www.sciencedirect.com
    Human astrocytes and microglia show augmented ingestion of synapses in Alzheimer’s disease via MFG-E8
    1
    1. scibot 01 Sep 2023
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      DOI: 10.1016/j.xcrm.2023.101175

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    sciencedirect.com/science/article/pii/S2666379123003282
  23. Jul 2023
  24. www.sciencedirect.com www.sciencedirect.com
    TREM2 receptor protects against complement-mediated synaptic loss by binding to complement C1q during neurodegeneration
    1
    1. scibot 13 Jul 2023
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      DOI: 10.1016/j.immuni.2023.06.016

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    sciencedirect.com/science/article/abs/pii/S107476132300273X
  25. Jun 2023
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Noncanonical Activity of Tissue Inhibitor of Metalloproteinases 2 (TIMP2) Improves Cognition and Synapse Density in Aging
    1
    1. scibot 21 Jun 2023
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      DOI: 10.1523/ENEURO.0031-23.2023

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    ncbi.nlm.nih.gov/pmc/articles/PMC10275401/
  27. www.jneurosci.org www.jneurosci.org
    Chronic neuronal inactivity utilizes the mTOR-TFEB pathway to drive transcription-dependent autophagy for homeostatic up-scaling
    1
    1. scibot 01 Jun 2023
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      DOI: 10.1523/JNEUROSCI.0146-23.2023

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    jneurosci.org/content/43/15/2631
  28. May 2023
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cross-Platform Synaptic Network Analysis of Human Entorhinal Cortex Identifies TWF2 as a Modulator of Dendritic Spine Length
    1
    1. scibot 23 May 2023
      RRID:AB_2292883

      DOI: 10.1523/JNEUROSCI.2102-22.2023

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    ncbi.nlm.nih.gov/pmc/articles/PMC10198456/
  30. www.sciencedirect.com www.sciencedirect.com
    Synaptic oligomeric tau in Alzheimer’s disease — A potential culprit in the spread of tau pathology through the brain
    1
    1. scibot 17 May 2023
      RRID:AB_2292883

      DOI: 10.1016/j.neuron.2023.04.020

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    sciencedirect.com/science/article/pii/S0896627323003057
  31. link.springer.com link.springer.com
    Late chronic local inflammation, synaptic alterations, vascular remodeling and arteriovenous malformations in the brains of male rats exposed to repetitive low-level blast overpressures
    1
    1. scibot 13 May 2023
      RRID:AB_2292883

      DOI: 10.1186/s40478-023-01553-6

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    link.springer.com/article/10.1186/s40478-023-01553-6
  32. Apr 2023
  33. www.sciencedirect.com www.sciencedirect.com
    A synaptic molecular dependency network in knockdown of autism- and schizophrenia-associated genes revealed by multiplexed imaging
    1
    1. scibot 26 Apr 2023
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      DOI: 10.1016/j.celrep.2023.112430

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    sciencedirect.com/science/article/pii/S2211124723004412
  34. Mar 2023
  35. www.mdpi.com www.mdpi.com
    Dysregulation of AMPA Receptor Trafficking and Intracellular Vesicular Sorting in the Prefrontal Cortex of Dopamine Transporter Knock-Out Rats
    1
    1. scibot 15 Mar 2023
      RRID:AB_2292883

      DOI: 10.3390/biom13030516

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    mdpi.com/2218-273X/13/3/516
  36. Dec 2022
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Huntingtin exon 1 deletion does not alter the subcellular distribution of huntingtin and gene transcription in mice
    1
    1. scibot 01 Dec 2022
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      DOI: 10.3389/fncel.2022.1021592

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    ncbi.nlm.nih.gov/pmc/articles/PMC9684630/
  38. Nov 2022
  39. journals.lww.com journals.lww.com
    Blunt dopamine transmission due to decreased GDNF in the... : Neural Regeneration Research
    1
    1. scibot 10 Nov 2022
      RRID:AB_2292883

      DOI: 10.4103/1673-5374.355816

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    journals.lww.com/nrronline/Fulltext/2023/05000/Blunt_dopamine_transmission_due_to_decreased_GDNF.30.aspx
  40. Sep 2022
  41. www.sciencedirect.com www.sciencedirect.com
    Post-developmental plasticity of the primary rod pathway allows restoration of visually guided behaviors
    1
    1. scibot 30 Sep 2022
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      DOI: 10.1016/j.cub.2022.09.016

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    sciencedirect.com/science/article/pii/S0960982222014609
  42. www.sciencedirect.com www.sciencedirect.com
    Engineered fast-dissociating antibody fragments for multiplexed super-resolution microscopy
    1
    1. scibot 21 Sep 2022
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      DOI: 10.1016/j.crmeth.2022.100301

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    sciencedirect.com/science/article/pii/S2667237522001837
  43. Aug 2022
  44. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Molecular and histological correlates of cognitive decline across age in male C57BL/6J mice
    1
    1. scibot 17 Aug 2022
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      DOI: 10.1002/brb3.2736

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    onlinelibrary.wiley.com/doi/10.1002/brb3.2736
  45. Feb 2022
  46. www.sciencedirect.com www.sciencedirect.com
    Co-packaging of opposing neurotransmitters in individual synaptic vesicles in the central nervous system
    1
    1. scibot 04 Feb 2022
      RRID:AB_2292883

      DOI: 10.1016/j.neuron.2022.01.007

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    sciencedirect.com/science/article/pii/S0896627322000071
  47. Dec 2021
  48. www.sciencedirect.com www.sciencedirect.com
    Shed CNTNAP2 ectodomain is detectable in CSF and regulates Ca2+ homeostasis and network synchrony via PMCA2/ATP2B2
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      DOI: 10.1016/j.neuron.2021.11.025

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    sciencedirect.com/science/article/pii/S0896627321009867
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Robust Expression of Functional NMDA Receptors in Human Induced Pluripotent Stem Cell-Derived Neuronal Cultures Using an Accelerated Protocol
    1
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      DOI: 10.3389/fnmol.2021.777049

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    ncbi.nlm.nih.gov/pmc/articles/PMC8661903/
  50. Nov 2021
  51. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Zinc induces reactive astrogliosis through ERK dependent activation of Stat3 and promotes synaptic degeneration
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      cat#3450

      DOI: 10.1111/jnc.15531

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    onlinelibrary.wiley.com/doi/10.1111/jnc.15531
  52. www.sciencedirect.com www.sciencedirect.com
    Role of adipocyte Na,K-ATPase oxidant amplification loop in cognitive decline and neurodegeneration
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      DOI: 10.1016/j.isci.2021.103262

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    sciencedirect.com/science/article/pii/S2589004221012311
  53. www.sciencedirect.com www.sciencedirect.com
    Identification of early-onset photoreceptor degeneration in transgenic mouse models of Alzheimer's disease
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      DOI: 10.1016/j.isci.2021.103327

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    sciencedirect.com/science/article/pii/S2589004221012967
  54. Aug 2021
  55. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Untitled document
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      DOI: 10.1002/cne.24616

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    onlinelibrary.wiley.com/doi/abs/10.1002/cne.24616
  56. Jul 2021
  57. onlinelibrary.wiley.com onlinelibrary.wiley.com
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      DOI: 10.1002/cne.24616

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    onlinelibrary.wiley.com/doi/full/10.1002/cne.24616
  58. www.jneurosci.org www.jneurosci.org
    Untitled document
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      DOI: 10.1523/JNEUROSCI.1285-18.2018

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    jneurosci.org/content/38/49/10411
  59. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Synaptic protein changes after a chronic period of sensorimotor perturbation in adult rats: a potential role of phosphorylation/O‐GlcNAcylation interplay
    1
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      DOI: 10.1111/jnc.14474

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  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Probabilistic fluorescence-based synapse detection
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    1. scibot 27 Jul 2021
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      DOI: 10.1371/journal.pcbi.1005493

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    ncbi.nlm.nih.gov/pmc/articles/PMC5411093/table/pcbi.1005493.t001/
  61. www.sciencedirect.com www.sciencedirect.com
    Neuronal activity recruits the CRTC1/CREB axis to drive transcription-dependent autophagy for maintaining late-phase LTD
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    Early-life inflammation promotes depressive symptoms in adolescence via microglial engulfment of dendritic spines
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  63. Jun 2021
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Arhgef2 regulates neural differentiation in the cerebral cortex through mRNA m6A-methylation of Npdc1 and Cend1
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  65. May 2021
  66. www.sciencedirect.com www.sciencedirect.com
    VEGF counteracts amyloid-β-induced synaptic dysfunction
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  67. Apr 2021
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A pain killer without analgesic tolerance designed by co-targeting PSD-95-nNOS interaction and α2-containning GABAARs
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  69. Mar 2021
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    Presynaptic activity and protein turnover are correlated at the single-synapse level
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  71. Feb 2021
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PKN1 Is a Novel Regulator of Hippocampal GluA1 Levels
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  73. Dec 2020
  74. www.mdpi.com www.mdpi.com
    Activity-Based Anorexia Dynamically Dysregulates the Glutamatergic Synapse in the Nucleus Accumbens of Female Adolescent Rats
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  75. Oct 2020
  76. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Anti‐Lingo‐1 antibody ameliorates spatial memory and synapse loss induced by chronic stress
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  77. www.sciencedirect.com www.sciencedirect.com
    Gut Microbiota-Induced Changes in β-Hydroxybutyrate Metabolism Are Linked to Altered Sociability and Depression in Alcohol Use Disorder
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  78. Sep 2020
  79. onlinelibrary.wiley.com onlinelibrary.wiley.com
    SynGAP Splice Variants Display Heterogeneous Spatio‐Temporal Expression And Subcellular Distribution In The Developing Mammalian Brain
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  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Zonisamide Ameliorates Cognitive Impairment by Inhibiting ER Stress in a Mouse Model of Type 2 Diabetes Mellitus
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  81. link.springer.com link.springer.com
    Central Cholinergic Synapse Formation in Optimized Primary Septal-Hippocampal Co-cultures
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  82. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Fluoxetine delays the cognitive function decline and synaptic changes in a transgenic mouse model of early Alzheimer's disease
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  83. www.jneurosci.org www.jneurosci.org
    A Mutation in Hnrnph1 That Decreases Methamphetamine-Induced Reinforcement, Reward, and Dopamine Release and Increases Synaptosomal hnRNP H and Mitochondrial Proteins
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    Quantitative immunoblotting analyses reveal that the abundance of actin, tubulin, synaptophysin and EEA1 proteins is altered in the brains of aged mice
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  85. Jan 2020
  86. www.sciencedirect.com www.sciencedirect.com
    The Ubiquitin-Editing Enzyme A20 Regulates Synapse Remodeling and Efficacy
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      DOI: 10.1016/j.brainres.2019.146569

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  87. www.jneurosci.org www.jneurosci.org
    Pituitary Adenylate Cyclase-Activating Polypeptide Modulates Dendritic Spine Maturation and Morphogenesis via MicroRNA-132 Upregulation
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      DOI: 10.1523/JNEUROSCI.2468-18.2019

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  88. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Early growth response‐1‐mediated down‐regulation of drebrin correlates with loss of dendritic spines
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      DOI: 10.1111/jnc.14031

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  89. www.sciencedirect.com www.sciencedirect.com
    Cytosolic Trapping of a Mitochondrial Heat Shock Protein Is an Early Pathological Event in Synucleinopathies
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  90. onlinelibrary.wiley.com onlinelibrary.wiley.com
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  91. Nov 2018
  92. www.sciencedirect.com www.sciencedirect.com
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  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Computational Synaptic Antibody Characterization Tool for Array Tomography
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    Visual Experience-Dependent Expression of Fn14 Is Required for Retinogeniculate Refinement
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    APOE4 Causes Widespread Molecular and Cellular Alterations Associated with Alzheimer’s Disease Phenotypes in Human iPSC-Derived Brain Cell Types
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    ApoE4 Accelerates Early Seeding of Amyloid Pathology
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  97. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Fibroblast growth factor 2 regulates activity and gene expression of human post‐mitotic excitatory neurons
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  99. Nov 2017
  100. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Probabilistic fluorescence-based synapse detection
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    Modulation of Autophagy by BDNF Underlies Synaptic Plasticity
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    The Auxiliary Calcium Channel Subunit α2δ4 Is Required for Axonal Elaboration, Synaptic Transmission, and Wiring of Rod Photoreceptors
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  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    GluA1 Phosphorylation Contributes to Postsynaptic Amplification of Neuropathic Pain in the Insular Cortex
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    Mapping homeostatic synaptic plasticity using cable properties of dendrites
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