101 Matching Annotations
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    Vaginal microbiota transfer ameliorates cesarean-associated neurodevelopmental deficits in mice via N-bc2S1P synthesis on neonatal skin
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    sciencedirect.com/science/article/pii/S1931312826001319
  3. Apr 2026
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    Tau seeds induce neurofibrillary tangle formation across brain regions via individual-specific connectivity
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    sciencedirect.com/science/article/pii/S0896627326001649
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    Evaluating Chronic Sex-Specific Changes in Glutamatergic Signaling Markers Following Traumatic Brain Injury
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    pmc.ncbi.nlm.nih.gov/articles/PMC13026189/
  6. Mar 2026
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    Human-specific features of the cerebellum and ZP2-regulated synapse development
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    sciencedirect.com/science/article/pii/S0092867426002217
  8. Feb 2026
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    Aberrant CDK4/6-driven cell-cycle reentry drives neuronal loss and defines a therapeutic target in C9orf72 ALS/FTD
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    pmc.ncbi.nlm.nih.gov/articles/PMC12856326/
  10. Jan 2026
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    Metabolic reprogramming during human neuron differentiation indicates glutaminase as a key determinant in Fragile X syndrome
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    sciencedirect.com/science/article/pii/S2211124725016298
  12. Dec 2025
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    s12974-025-03648-4_reference-html.html
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    Ceftriaxone alleviates mitochondrial damage through the inhibition of extrasynaptic NMDA receptor-mediated changes in intracellular calcium levels to improve cognitive deficits in APP/PS1 mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC12670740/
  15. Oct 2025
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    TREK-1 Channel Blockade Mediates the Antidepressant-like Effects of Hydroxynorketamine
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    sciencedirect.com/science/article/pii/S0028390825004599
  17. Sep 2025
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    Deletion of the SHORT Syndrome Gene Prkce Results in Brain Atrophy and Cognitive and Motor Behavior Deficits in Mice
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    link.springer.com/article/10.1007/s12264-025-01497-y
  19. Jul 2025
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    Synapses and dendritic spines are eliminated in the primary visual cortex of mice subjected to chronic intraocular pressure elevation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12296469/
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    Subchronic amphetamine decreases hyperactivity, anti-social behaviour and anhedonia in dopamine transporter knockout rats: role of prefrontal glutamate
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    sciencedirect.com/science/article/pii/S0028390825003053
  22. May 2025
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Serine/Threonine Kinase NDR2 Regulates Integrin Signaling, Synapse Formation, and Synaptic Plasticity in the Hippocampus
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    pmc.ncbi.nlm.nih.gov/articles/PMC12120816/
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    Tomatidine Ameliorates Diabetes-Induced Cognitive Impairment and Tau Hyperphosphorylation Through the AMPK-TFEB Pathway
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    onlinelibrary.wiley.com/doi/10.1111/jnc.70087
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    RNF13 variants L311S and L312P associated with developmental epileptic encephalopathy alter dendritic organization in hippocampal neurons
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    A novel carbamate-based hybrid derivative with anti-neuroinflammatory properties as a selective butyrylcholinesterase inhibitor for Alzheimer's disease therapy
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    sciencedirect.com/science/article/pii/S0045206825004316
  27. Apr 2025
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    Donepezil Improves PSD95 Expression, Mitigates Neuroinflammation via PI3K/Akt/NF-κB and Mitochondrial Dysfunction in a Rodent Model of Subarachnoid Haemorrhage
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    Repeated cocaine exposure and prolonged withdrawal induce spatial memory impairment and dysregulate the glutamatergic synapse composition in the dorsal hippocampus of male rats
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    sciencedirect.com/science/article/pii/S0028390825001595
  30. Mar 2025
  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Sub-Immunosuppressive Tacrolimus Ameliorates Amyloid-Beta and Tau Pathology in 3xTg-AD Mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC11898583/
  32. Dec 2024
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  34. Nov 2024
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    Regulation of synapse density by Pumilio RNA-binding proteins
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  36. Oct 2024
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    Compound (E)-2-(3,4-dihydroxystyryl)-3-hydroxy-4H-pyran-4-one downregulation of Galectin-3 ameliorates Aβ pathogenesis-induced neuroinflammation in 5 × FAD mice
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  38. Sep 2024
  39. analyticalsciencejournals.onlinelibrary.wiley.com analyticalsciencejournals.onlinelibrary.wiley.com
    Epigenetic alternations in the SYP and DLG4 genes due to low-level methylmercury exposure during neuronal differentiation in vitro
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    analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/jat.4690
  40. currentprotocols.onlinelibrary.wiley.com currentprotocols.onlinelibrary.wiley.com
    Reproducible Differentiation of Human Pluripotent Stem Cells into Two-Dimensional Cortical Neuron Cultures with Checkpoints for Success
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    currentprotocols.onlinelibrary.wiley.com/doi/10.1002/cpz1.948
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    Sodium butyrate improves cognitive dysfunction in high-fat diet/ streptozotocin-induced type 2 diabetic mice by ameliorating hippocampal mitochondrial damage through regulating AMPK/PGC-1α pathway
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  42. Aug 2024
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chronic Lithium Treatment Alters NMDA and AMPA Receptor Synaptic Availability and Dendritic Spine Organization in the Rat Hippocampus
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    ncbi.nlm.nih.gov/pmc/articles/PMC11333793/
  44. Jul 2024
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    A hominoid-specific signaling axis regulating the tempo of synaptic maturation
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  46. Jun 2024
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Communal nesting shapes the sex-dependent glutamatergic response to early life stress in the rat prefrontal cortex
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    ncbi.nlm.nih.gov/pmc/articles/PMC11148342/
  48. May 2024
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    Transcranial Magneto-Acoustic Stimulation Protects Synaptic Rehabilitation from Amyloid-Beta Plaques via Regulation of Microglial Functions
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    mdpi.com/1422-0067/25/9/4651
  50. Apr 2024
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Edaravone Dexborneol mitigates pathology in animal and cell culture models of Alzheimer’s disease by inhibiting neuroinflammation and neuronal necroptosis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11056062/
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    Altered GM1 catabolism affects NMDAR-mediated Ca2+ signaling at ER-PM junctions and increases synaptic spine formation in a GM1-gangliosidosis model
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  53. Mar 2024
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    Translational modulator ISRIB alleviates synaptic and behavioral phenotypes in Fragile X syndrome
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  55. Feb 2024
  56. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Brief exposure to enriched environment rapidly shapes the glutamate synapses in the rat brain: A metaplastic fingerprint
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    onlinelibrary.wiley.com/doi/10.1111/ejn.16279
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    Inhibition of mGluR5/PI3K-AKT Pathway Alleviates Alzheimer’s Disease-Like Pathology Through the Activation of Autophagy in 5XFAD Mice
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  58. Jan 2024
  59. www.jneurosci.org www.jneurosci.org
    Nascent Aβ42 Fibrillization in Synaptic Endosomes Precedes Plaque Formation in a Mouse Model of Alzheimer's-like β-Amyloidosis
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    jneurosci.org/content/43/50/8812
  60. Dec 2023
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    Developing a Toolbox of Antibodies Validated for Array Tomography-Based Imaging of Brain Synapses
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    ncbi.nlm.nih.gov/pmc/articles/PMC10748464/
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    Pre- and postsynaptic nanostructures increase in size and complexity after induction of long-term potentiation
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    sciencedirect.com/science/article/pii/S2589004223027566
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    Developing a Toolbox of Antibodies Validated for Array Tomography-Based Imaging of Brain Synapses
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    ncbi.nlm.nih.gov/pmc/articles/PMC10327040/
  64. Oct 2023
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Behavioral and neuropathological characterization over the adult lifespan of the human tau knock-in mouse
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    ncbi.nlm.nih.gov/pmc/articles/PMC10576558/
  66. Sep 2023
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    Parkinson’s disease-linked parkin mutation disrupts recycling of synaptic vesicles in human dopaminergic neurons
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    sciencedirect.com/science/article/abs/pii/S0896627323006293
  68. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Plk2 promotes synaptic destabilization through disruption of N-cadherin adhesion complexes during homeostatic adaptation to hyperexcitation
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15948
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    Human astrocytes and microglia show augmented ingestion of synapses in Alzheimer’s disease via MFG-E8
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    sciencedirect.com/science/article/pii/S2666379123003282
  70. Jul 2023
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    TREM2 receptor protects against complement-mediated synaptic loss by binding to complement C1q during neurodegeneration
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    sciencedirect.com/science/article/abs/pii/S107476132300273X
  72. Jun 2023
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Noncanonical Activity of Tissue Inhibitor of Metalloproteinases 2 (TIMP2) Improves Cognition and Synapse Density in Aging
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    ncbi.nlm.nih.gov/pmc/articles/PMC10275401/
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    Chronic neuronal inactivity utilizes the mTOR-TFEB pathway to drive transcription-dependent autophagy for homeostatic up-scaling
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    jneurosci.org/content/43/15/2631
  75. May 2023
  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cross-Platform Synaptic Network Analysis of Human Entorhinal Cortex Identifies TWF2 as a Modulator of Dendritic Spine Length
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    ncbi.nlm.nih.gov/pmc/articles/PMC10198456/
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    Synaptic oligomeric tau in Alzheimer’s disease — A potential culprit in the spread of tau pathology through the brain
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    Late chronic local inflammation, synaptic alterations, vascular remodeling and arteriovenous malformations in the brains of male rats exposed to repetitive low-level blast overpressures
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    link.springer.com/article/10.1186/s40478-023-01553-6
  79. Apr 2023
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    A synaptic molecular dependency network in knockdown of autism- and schizophrenia-associated genes revealed by multiplexed imaging
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  81. Mar 2023
  82. www.mdpi.com www.mdpi.com
    Dysregulation of AMPA Receptor Trafficking and Intracellular Vesicular Sorting in the Prefrontal Cortex of Dopamine Transporter Knock-Out Rats
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    mdpi.com/2218-273X/13/3/516
  83. Dec 2022
  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Huntingtin exon 1 deletion does not alter the subcellular distribution of huntingtin and gene transcription in mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC9684630/
  85. Nov 2022
  86. journals.lww.com journals.lww.com
    Blunt dopamine transmission due to decreased GDNF in the... : Neural Regeneration Research
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  87. Sep 2022
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    Post-developmental plasticity of the primary rod pathway allows restoration of visually guided behaviors
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    sciencedirect.com/science/article/pii/S0960982222014609
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    Engineered fast-dissociating antibody fragments for multiplexed super-resolution microscopy
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  90. Aug 2022
  91. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Molecular and histological correlates of cognitive decline across age in male C57BL/6J mice
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    onlinelibrary.wiley.com/doi/10.1002/brb3.2736
  92. Feb 2022
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    Co-packaging of opposing neurotransmitters in individual synaptic vesicles in the central nervous system
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  94. Dec 2021
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    Shed CNTNAP2 ectodomain is detectable in CSF and regulates Ca2+ homeostasis and network synchrony via PMCA2/ATP2B2
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    Robust Expression of Functional NMDA Receptors in Human Induced Pluripotent Stem Cell-Derived Neuronal Cultures Using an Accelerated Protocol
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    ncbi.nlm.nih.gov/pmc/articles/PMC8661903/
  97. Nov 2021
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    Zinc induces reactive astrogliosis through ERK dependent activation of Stat3 and promotes synaptic degeneration
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15531
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    Role of adipocyte Na,K-ATPase oxidant amplification loop in cognitive decline and neurodegeneration
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    Identification of early-onset photoreceptor degeneration in transgenic mouse models of Alzheimer's disease
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  101. Aug 2021
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    onlinelibrary.wiley.com/doi/abs/10.1002/cne.24616
  103. Jul 2021
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    Synaptic protein changes after a chronic period of sensorimotor perturbation in adult rats: a potential role of phosphorylation/O‐GlcNAcylation interplay
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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.14474
  107. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Probabilistic fluorescence-based synapse detection
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    ncbi.nlm.nih.gov/pmc/articles/PMC5411093/table/pcbi.1005493.t001/
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    Neuronal activity recruits the CRTC1/CREB axis to drive transcription-dependent autophagy for maintaining late-phase LTD
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    sciencedirect.com/science/article/pii/S2211124721007968
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    Early-life inflammation promotes depressive symptoms in adolescence via microglial engulfment of dendritic spines
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  110. Jun 2021
  111. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Arhgef2 regulates neural differentiation in the cerebral cortex through mRNA m6A-methylation of Npdc1 and Cend1
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    ncbi.nlm.nih.gov/pmc/articles/PMC8185223/
  112. May 2021
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    VEGF counteracts amyloid-β-induced synaptic dysfunction
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  114. Apr 2021
  115. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A pain killer without analgesic tolerance designed by co-targeting PSD-95-nNOS interaction and α2-containning GABAARs
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    ncbi.nlm.nih.gov/pmc/articles/PMC8058733/
  116. Mar 2021
  117. www.sciencedirect.com www.sciencedirect.com
    Presynaptic activity and protein turnover are correlated at the single-synapse level
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    sciencedirect.com/science/article/pii/S2211124721001558
  118. Feb 2021
  119. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PKN1 Is a Novel Regulator of Hippocampal GluA1 Levels
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    ncbi.nlm.nih.gov/pmc/articles/PMC7892898/
  120. Dec 2020
  121. www.mdpi.com www.mdpi.com
    Activity-Based Anorexia Dynamically Dysregulates the Glutamatergic Synapse in the Nucleus Accumbens of Female Adolescent Rats
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    mdpi.com/2072-6643/12/12/3661
  122. Oct 2020
  123. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Anti‐Lingo‐1 antibody ameliorates spatial memory and synapse loss induced by chronic stress
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    onlinelibrary.wiley.com/doi/10.1002/cne.25038
  124. www.sciencedirect.com www.sciencedirect.com
    Gut Microbiota-Induced Changes in β-Hydroxybutyrate Metabolism Are Linked to Altered Sociability and Depression in Alcohol Use Disorder
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    sciencedirect.com/science/article/pii/S2211124720312274
  125. Sep 2020
  126. onlinelibrary.wiley.com onlinelibrary.wiley.com
    SynGAP Splice Variants Display Heterogeneous Spatio‐Temporal Expression And Subcellular Distribution In The Developing Mammalian Brain
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    onlinelibrary.wiley.com/doi/10.1111/jnc.14988
  127. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Zonisamide Ameliorates Cognitive Impairment by Inhibiting ER Stress in a Mouse Model of Type 2 Diabetes Mellitus
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    ncbi.nlm.nih.gov/pmc/articles/PMC7367218/
  128. link.springer.com link.springer.com
    Central Cholinergic Synapse Formation in Optimized Primary Septal-Hippocampal Co-cultures
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