129 Matching Annotations
  1. Sep 2026
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Estrogen deprivation exacerbates Alzheimer’s disease pathology through neuronal CTSS signaling
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    pmc.ncbi.nlm.nih.gov/articles/PMC13570535/
  3. Aug 2026
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    δ2-Protocadherins organize parallel indirect basal ganglia circuits
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    pmc.ncbi.nlm.nih.gov/articles/PMC13496169/
  5. Jul 2026
  6. www.sciencedirect.com www.sciencedirect.com
    Neurexin-1γ drives synaptic transmission through structural integration of neurotransmitter release machinery and postsynaptic receptor nanodomains
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    sciencedirect.com/science/article/pii/S0896627326004861
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    Temporally segregated functions for Gfi1 in the development and maintenance of direction selectivity in the vertebrate retina
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    sciencedirect.com/science/article/pii/S0960982226007992
  8. May 2026
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    Wake-active brainstem GABA neurons signal sleep pressure by upregulating AMPA receptors to drive recovery sleep
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    sciencedirect.com/science/article/pii/S0960982226005294
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Translatome profiling reveals opposing alterations in inhibitory and excitatory neurons of fragile X mice and identifies EPAC2 as a therapeutic target
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    pmc.ncbi.nlm.nih.gov/articles/PMC13242833/
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Multiparity exacerbates Aβ accumulation and promotes cellular senescence in a mouse model of amyloidosis
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    pmc.ncbi.nlm.nih.gov/articles/PMC13154431/
  12. Mar 2026
  13. www.sciencedirect.com www.sciencedirect.com
    Soluble α2δ-1, altered in disease CSF, modulates network homeostasis and rescues deficits in a neuropsychiatric mouse model
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    sciencedirect.com/science/article/pii/S0896627326000875
  14. Nov 2025
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Coro1A and TRIM67 collaborate in netrin-dependent neuronal morphogenesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12614643/
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    Memory engram synapse 3D macromolecular architecture visualized by cryoCLEM-guided cryoET
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    sciencedirect.com/science/article/pii/S0969212625004010
  17. Sep 2025
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Anti-P antibodies that impair memory perturb hippocampal glutamatergic receptor trafficking, synapse structure and microglia
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    pmc.ncbi.nlm.nih.gov/articles/PMC12465742/
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    Slit2/Robo1 signaling constrains image stabilization responses to preserve ethologically favorable directional asymmetry
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    sciencedirect.com/science/article/pii/S0960982225010966
  20. Aug 2025
  21. 52.53.155.43 52.53.155.43
    1-s2.0-S2589004225016967-main-html.html
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    52.53.155.43/b3f84da895cc36df97322da0dfda604a5cad7552/1-s2.0-S2589004225016967-main-html.html
  22. Jun 2025
  23. 52.53.155.43 52.53.155.43
    15327.full-html.html
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    52.53.155.43/146caa3d68f89f6d42401d81f9ec080152b827ee/15327.full-html.html
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    TNFR2 contributes to synaptic potentiation failure in hippocampal synapses and memory loss in a familial Alzheimer’s disease mouse model
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    sciencedirect.com/science/article/pii/S0889159125002363
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Long-term muscarinic inhibition increases intrinsic excitability through the upregulation of A-type potassium currents in cortical neurons
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    pmc.ncbi.nlm.nih.gov/articles/PMC12149742/
  26. www.sciencedirect.com www.sciencedirect.com
    Regulation of hippocampal excitatory synapse development by the adhesion G-protein coupled receptor brain-specific angiogenesis inhibitor 2 (BAI2/ADGRB2)
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    sciencedirect.com/science/article/pii/S1044743125000259
  27. May 2025
  28. www.jneurosci.org www.jneurosci.org
    A critical role of Neuroligin 2 C-terminus in OCD and social behavior
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    jneurosci.org/content/45/19/e1417242025
  29. Feb 2025
  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Loss of the proton-activated chloride channel in neurons impairs AMPA receptor endocytosis and LTD via endosomal hyper-acidification
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    pmc.ncbi.nlm.nih.gov/articles/PMC11938102/
  31. Jan 2025
  32. www.sciencedirect.com www.sciencedirect.com
    The Hao-Fountain syndrome protein USP7 regulates neuronal connectivity in the brain via a novel p53-independent ubiquitin signaling pathway
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    sciencedirect.com/science/article/pii/S2211124725000026
  33. Nov 2024
  34. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Modulation of SNARE-dependent exocytosis in astrocytes improves neuropathology in Huntington's disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC11583919/
  35. Oct 2024
  36. www.sciencedirect.com www.sciencedirect.com
    CTNND2 moderates the pace of synaptic maturation and links human evolution to synaptic neoteny
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    sciencedirect.com/science/article/pii/S2211124724011483
  37. www.sciencedirect.com www.sciencedirect.com
    The TMEM132B-GABAA receptor complex controls alcohol actions in the brain
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    sciencedirect.com/science/article/pii/S0092867424010249
  38. Sep 2024
  39. www.sciencedirect.com www.sciencedirect.com
    Developmental refinement of the active zone nanotopography and axon wiring at the somatosensory thalamus
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    sciencedirect.com/science/article/pii/S2211124724011215
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Fluorescence-Based Quantitative Synapse Analysis for Cell Type-Specific Connectomics
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    ncbi.nlm.nih.gov/pmc/articles/PMC6873163/
  41. Jul 2024
  42. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Loss of the polarity protein Par3 promotes dendritic spine neoteny and enhances learning and memory
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    pmc.ncbi.nlm.nih.gov/articles/PMC11263792/
  43. Apr 2024
  44. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Overexpression of α-Klotho isoforms promotes distinct Effects on BDNF-Induced Alterations in Dendritic Morphology
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    pmc.ncbi.nlm.nih.gov/articles/PMC11496329/
  45. Feb 2024
  46. www.sciencedirect.com www.sciencedirect.com
    Loss of GTF2I promotes neuronal apoptosis and synaptic reduction in human cellular models of neurodevelopment
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    sciencedirect.com/science/article/pii/S2211124724001955
  47. www.mdpi.com www.mdpi.com
    Oxidative Stress Plays an Important Role in Glutamatergic Excitotoxicity-Induced Cochlear Synaptopathy: Implication for Therapeutic Molecules Screening
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    mdpi.com/2076-3921/13/2/149
  48. Jan 2024
  49. www.science.org www.science.org
    Astrocytic TDP-43 dysregulation impairs memory by modulating antiviral pathways and interferon-inducible chemokines
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    science.org/doi/10.1126/sciadv.ade1282
  50. Dec 2023
  51. www.sciencedirect.com www.sciencedirect.com
    Reduced lysosomal density in neuronal dendrites mediates deficits in synaptic plasticity in Huntington’s disease
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    sciencedirect.com/science/article/pii/S2211124723015851
  52. Oct 2023
  53. www.nature.com www.nature.com
    Antibody-directed extracellular proximity biotinylation reveals that Contactin-1 regulates axo-axonic innervation of axon initial segments
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    nature.com/articles/s41467-023-42273-8
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Celf4 controls mRNA translation underlying synaptic development in the prenatal mammalian neocortex
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    ncbi.nlm.nih.gov/pmc/articles/PMC10533865/
  55. Sep 2023
  56. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Plk2 promotes synaptic destabilization through disruption of N-cadherin adhesion complexes during homeostatic adaptation to hyperexcitation
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15948
  57. Aug 2023
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Large-scale survey of excitatory synapses reveals sublamina-specific and asymmetric synapse patterns in a neurodegenerative circuit
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    ncbi.nlm.nih.gov/pmc/articles/PMC10440711/
  59. www.nature.com www.nature.com
    Platelet-derived exerkine CXCL4/platelet factor 4 rejuvenates hippocampal neurogenesis and restores cognitive function in aged mice
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    nature.com/articles/s41467-023-39873-9
  60. www.sciencedirect.com www.sciencedirect.com
    A Noelin-organized extracellular network of proteins required for constitutive and context-dependent anchoring of AMPA-receptors
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    sciencedirect.com/science/article/pii/S0896627323005469
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Preserving extracellular space for high-quality optical and ultrastructural studies of whole mammalian brains
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    ncbi.nlm.nih.gov/pmc/articles/PMC10391564/
  62. Jun 2023
  63. www.nature.com www.nature.com
    Kv7/KCNQ potassium channels in cortical hyperexcitability and juvenile seizure-related death in Ank2-mutant mice
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    nature.com/articles/s41467-023-39203-z
  64. www.sciencedirect.com www.sciencedirect.com
    Activity-dependent tau cleavage by caspase-3 promotes neuronal dysfunction and synaptotoxicity
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    sciencedirect.com/science/article/pii/S2589004223009823
  65. May 2023
  66. link.springer.com link.springer.com
    The vestibular calyceal junction is dismantled following subchronic streptomycin in rats and sensory epithelium stress in humans
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    link.springer.com/article/10.1007/s00204-023-03518-z
  67. www.sciencedirect.com www.sciencedirect.com
    Deep proteomics identifies shared molecular pathway alterations in synapses of patients with schizophrenia and bipolar disorder and mouse model
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    sciencedirect.com/science/article/pii/S2211124723005089
  68. Apr 2023
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Astrocytic TDP-43 dysregulation impairs memory by modulating antiviral pathways and interferon-inducible chemokines
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    ncbi.nlm.nih.gov/pmc/articles/PMC10115456/
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Antibody-directed extracellular proximity biotinylation reveals Contactin-1 regulates axo-axonic innervation of axon initial segments
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10028829/
  71. Mar 2023
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Asymmetric retinal direction tuning predicts optokinetic eye movements across stimulus conditions
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    ncbi.nlm.nih.gov/pmc/articles/PMC10023158/
  73. Jan 2023
  74. www.sciencedirect.com www.sciencedirect.com
    Artificial extracellular matrix scaffolds of mobile molecules enhance maturation of human stem cell-derived neurons
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    sciencedirect.com/science/article/pii/S1934590922004945
  75. link.springer.com link.springer.com
    Development and Optimization of a Multilayer Rat Purkinje Neuron Culture
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    link.springer.com/article/10.1007/s12311-022-01510-4
  76. www.sciencedirect.com www.sciencedirect.com
    Human cortical interneurons optimized for grafting specifically integrate, abort seizures, and display prolonged efficacy without over-inhibition
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    sciencedirect.com/science/article/pii/S089662732201087X
  77. www.sciencedirect.com www.sciencedirect.com
    Efficient generation of lower induced motor neurons by coupling Ngn2 expression with developmental cues
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    sciencedirect.com/science/article/pii/S2211124722017958
  78. Nov 2022
  79. www.sciencedirect.com www.sciencedirect.com
    Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies
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    sciencedirect.com/science/article/pii/S2211124722015522
  80. www.sciencedirect.com www.sciencedirect.com
    Development of single-molecule ubiquitination mediated fluorescence complementation to visualize protein ubiquitination dynamics in dendrites
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    sciencedirect.com/science/article/pii/S2211124722015297
  81. Oct 2022
  82. link.springer.com link.springer.com
    Retrosplenial and subicular inputs converge on superficially projecting layer V neurons of medial entorhinal cortex
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    link.springer.com/article/10.1007/s00429-022-02578-8
  83. Aug 2022
  84. www.sciencedirect.com www.sciencedirect.com
    Warburg-like metabolic transformation underlies neuronal degeneration in sporadic Alzheimer’s disease
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    sciencedirect.com/science/article/pii/S1550413122003138
  85. Jul 2022
  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Slitrk2 deficiency causes hyperactivity with altered vestibular function and serotonergic dysregulation
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    ncbi.nlm.nih.gov/pmc/articles/PMC9250022/
  87. Jun 2022
  88. link.springer.com link.springer.com
    Bidirectional regulation of synaptic SUMOylation by Group 1 metabotropic glutamate receptors
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    link.springer.com/article/10.1007/s00018-022-04405-z
  89. Apr 2022
  90. www.sciencedirect.com www.sciencedirect.com
    A presynaptic phosphosignaling hub for lasting homeostatic plasticity
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    sciencedirect.com/science/article/pii/S2211124722004545
  91. Mar 2022
  92. www.sciencedirect.com www.sciencedirect.com
    Neurons undergo pathogenic metabolic reprogramming in models of familial ALS
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    sciencedirect.com/science/article/pii/S2212877822000370
  93. www.jneurosci.org www.jneurosci.org
    Stabilization of Spine Synaptopodin by mGluR1 Is Required for mGluR-LTD
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    jneurosci.org/content/42/9/1666
  94. Feb 2022
  95. link.springer.com link.springer.com
    LiCl treatment leads to long-term restoration of spine maturation and synaptogenesis in adult Tbr1 mutants
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    link.springer.com/article/10.1186/s11689-022-09421-5
  96. Oct 2021
  97. www.sciencedirect.com www.sciencedirect.com
    Multiomics of synaptic junctions reveals altered lipid metabolism and signaling following environmental enrichment
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    sciencedirect.com/science/article/pii/S2211124721012572
  98. Sep 2021
  99. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hippocampal overexpression of NOS1AP promotes endophenotypes related to mental disorders
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    ncbi.nlm.nih.gov/pmc/articles/PMC8403735/
  100. Aug 2021
  101. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Localization, proteomics, and metabolite profiling reveal a putative vesicular transporter for UDP-glucose
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    ncbi.nlm.nih.gov/pmc/articles/PMC8373376/
  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Synaptic Scaffolds, Ion Channels and Polyamines in Mouse Photoreceptor Synapses: Anatomy of a Signaling Complex
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    ncbi.nlm.nih.gov/pmc/articles/PMC8356055/
  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transplantable human motor networks as a neuron-directed strategy for spinal cord injury
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    ncbi.nlm.nih.gov/pmc/articles/PMC8333163/
  104. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Presynaptic Scaffold Protein Bassoon in Forebrain Excitatory Neurons Mediates Hippocampal Circuit Maturation: Potential Involvement of TrkB Signalling
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    ncbi.nlm.nih.gov/pmc/articles/PMC8347324/
  105. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    ncbi.nlm.nih.gov/pmc/articles/PMC6384025/
  106. www.eneuro.org www.eneuro.org
    Untitled document
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    eneuro.org/content/4/4/eneuro.0040-17.2017
  107. www.frontiersin.org www.frontiersin.org
    The Social Component of Environmental Enrichment Is a Pro-neurogenic Stimulus in Adult c57BL6 Female Mice
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    frontiersin.org/article/10.3389/fcell.2019.00062/full
  108. Jul 2021
  109. www.jneurosci.org www.jneurosci.org
    Untitled document
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    jneurosci.org/content/34/46/15327
  110. www.sciencedirect.com www.sciencedirect.com
    RbAp48 Protein Is a Critical Component of GPR158/OCN Signaling and Ameliorates Age-Related Memory Loss
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    sciencedirect.com/science/article/pii/S2211124718315377
  111. www.nature.com www.nature.com
    Activity-dependent changes in synaptic protein complex composition are consistent in different detergents despite differential solubility
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    nature.com/articles/s41598-019-46690-y
  112. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Computational Synaptic Antibody Characterization Tool for Array Tomography
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    ncbi.nlm.nih.gov/pmc/articles/PMC6057115/
  113. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PTPσ drives excitatory presynaptic assembly via various extracellular and intracellular mechanisms
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    ncbi.nlm.nih.gov/pmc/articles/PMC6705959/
  114. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Multiple roles of afadin in the ultrastructural morphogenesis of mouse hippocampal mossy fiber synapses
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    onlinelibrary.wiley.com/doi/10.1002/cne.24238/full
  115. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Loss of SynDIG1 Reduces Excitatory Synapse Maturation But Not Formation In Vivo
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    ncbi.nlm.nih.gov/pmc/articles/PMC5073248/
  116. www.sciencedirect.com www.sciencedirect.com
    GRASP1 Regulates Synaptic Plasticity and Learning through Endosomal Recycling of AMPA Receptors
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    sciencedirect.com/science/article/pii/S0896627317301393
  117. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Regulation of Neural Circuit Development by Cadherin-11 Provides Implications for Autism
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    ncbi.nlm.nih.gov/pmc/articles/PMC8266214/
  118. link.springer.com link.springer.com
    W246G Mutant ELOVL4 Impairs Synaptic Plasticity in Parallel and Climbing Fibers and Causes Motor Defects in a Rat Model of SCA34
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    link.springer.com/article/10.1007/s12035-021-02439-1
  119. Jun 2021
  120. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Cleaved PINK1 induces neuronal plasticity through PKA-mediated BDNF functional regulation
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    onlinelibrary.wiley.com/doi/10.1002/jnr.24854
  121. May 2021
  122. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neuronal pentraxin 1: A synaptic-derived plasma biomarker in Alzheimer's disease
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    ncbi.nlm.nih.gov/pmc/articles/PMC8092920/
  123. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A photoswitchable GPCR-based opsin for presynaptic inhibition
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    ncbi.nlm.nih.gov/pmc/articles/PMC8194251/
  124. Feb 2021
  125. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Subcellular sorting of neuregulins controls the assembly of excitatory-inhibitory cortical circuits
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    ncbi.nlm.nih.gov/pmc/articles/PMC7755390/
  126. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Rapid 3D Enhanced Resolution Microscopy Reveals Diversity in Dendritic Spinule Dynamics, Regulation, and Function
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    ncbi.nlm.nih.gov/pmc/articles/PMC7879711/
  127. Nov 2020
  128. www.cell.com www.cell.com
    Synapse and Active Zone Assembly in the Absence of Presynaptic Ca2+ Channels and Ca2+ Entry
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    cell.com/neuron/abstract/S0896-6273(20)30401-3
  129. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Neuronal surface P antigen (NSPA) modulates postsynaptic NMDAR stability through ubiquitination of tyrosine phosphatase PTPMEG
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  130. Oct 2020
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  132. Sep 2020
  133. www.embopress.org www.embopress.org
    Neurexins cluster Ca2+ channels within the presynaptic active zone
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    Differential mechanisms of tolerance induced by NMDA and DHPG preconditioning
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    The Protein Arginine Methyltransferase PRMT8 and Substrate G3BP1 Control Rac1-PAK1 Signaling and Actin Cytoskeleton for Dendritic Spine Maturation
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    Neuronal L-Type Calcium Channel Signaling to the Nucleus Requires a Novel CaMKIIα-Shank3 Interaction
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    AMPAR Auxiliary Protein SHISA6 Facilitates Purkinje Cell Synaptic Excitability and Procedural Memory Formation
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    Certain ortho-hydroxylated brominated ethers are promiscuous kinase inhibitors that impair neuronal signaling and neurodevelopmental processes
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    Enhancing WNT Signaling Restores Cortical Neuronal Spine Maturation and Synaptogenesis in Tbr1 Mutants
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    Receptor protein tyrosine phosphatase delta is not essential for synapse maintenance or transmission at hippocampal synapses
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    ORANGE: A CRISPR/Cas9-based genome editing toolbox for epitope tagging of endogenous proteins in neurons
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    LRRTMs Organize Synapses through Differential Engagement of Neurexin and PTPσ
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    Pre- and post-synaptic roles for DCC in memory consolidation in the adult mouse hippocampus
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  146. Jan 2020
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    Early treatment with C1 esterase inhibitor improves weight but not memory deficits in a rat model of status epilepticus
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    Sam68 Enables Metabotropic Glutamate Receptor-Dependent LTD in Distal Dendritic Regions of CA1 Hippocampal Neurons
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    Bi-allelic Variants in METTL5 Cause Autosomal-Recessive Intellectual Disability and Microcephaly
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    Shank Proteins Couple the Endocytic Zone to the Postsynaptic Density to Control Trafficking and Signaling of Metabotropic Glutamate Receptor 5
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    NMDAR-Activated PP1 Dephosphorylates GluN2B to Modulate NMDAR Synaptic Content
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    An ER Assembly Line of AMPA-Receptors Controls Excitatory Neurotransmission and Its Plasticity
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    Autism and Schizophrenia-Associated CYFIP1 Regulates the Balance of Synaptic Excitation and Inhibition
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  157. Nov 2018
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    High Fidelity Cryopreservation and Recovery of Primary Rodent Cortical Neurons
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    USP8 Deubiquitinates SHANK3 to Control Synapse Density and SHANK3 Activity-dependent Protein Levels
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    Rbfox1 Regulates Synaptic Transmission through the Inhibitory Neuron-Specific vSNARE Vamp1
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    Control of Homeostatic Synaptic Plasticity by AKAP-Anchored Kinase and Phosphatase Regulation of Ca2+-Permeable AMPA Receptors
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    Cadherin-10 Maintains Excitatory/Inhibitory Ratio through Interactions with Synaptic Proteins
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  167. Nov 2017
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    Histone Hypervariants H2A.Z.1 and H2A.Z.2 Play Independent and Context-Specific Roles in Neuronal Activity-Induced Transcription of Arc/Arg3.1 and Other Immediate Early Genes
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    Mouse Tmem135 mutation reveals a mechanism involving mitochondrial dynamics that leads to age-dependent retinal pathologies
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    Membrane‐associated guanylate kinase scaffolds organize a horizontal cell synaptic complex restricted to invaginating contacts with photoreceptors
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    Proteomic Analysis of Unbounded Cellular Compartments: Synaptic Clefts
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    Membrane-bound glucocorticoid receptors on distinct nociceptive neurons as potential targets for pain control through rapid non-genomic effects
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    Ablation of ErbB4 from excitatory neurons leads to reduced dendritic spine density in mouse prefrontal cortex
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    Regulation of Neuronal Gene Expression and Survival by Basal NMDA Receptor Activity: A Role for Histone Deacetylase 4
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