130 Matching Annotations
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    Opposing excitatory and inhibitory synaptic pathologies drive ZC4H2-associated intellectual disability
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    sciencedirect.com/science/article/pii/S0896627326007786
  3. Sep 2026
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    Estrogen deprivation exacerbates Alzheimer’s disease pathology through neuronal CTSS signaling
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    pmc.ncbi.nlm.nih.gov/articles/PMC13570535/
  5. Aug 2026
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    δ2-Protocadherins organize parallel indirect basal ganglia circuits
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    pmc.ncbi.nlm.nih.gov/articles/PMC13496169/
  7. Jul 2026
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    Neurexin-1γ drives synaptic transmission through structural integration of neurotransmitter release machinery and postsynaptic receptor nanodomains
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    sciencedirect.com/science/article/pii/S0896627326004861
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    Temporally segregated functions for Gfi1 in the development and maintenance of direction selectivity in the vertebrate retina
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    sciencedirect.com/science/article/pii/S0960982226007992
  10. May 2026
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    Wake-active brainstem GABA neurons signal sleep pressure by upregulating AMPA receptors to drive recovery sleep
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    sciencedirect.com/science/article/pii/S0960982226005294
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    Translatome profiling reveals opposing alterations in inhibitory and excitatory neurons of fragile X mice and identifies EPAC2 as a therapeutic target
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    Multiparity exacerbates Aβ accumulation and promotes cellular senescence in a mouse model of amyloidosis
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  14. Mar 2026
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    Soluble α2δ-1, altered in disease CSF, modulates network homeostasis and rescues deficits in a neuropsychiatric mouse model
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  16. Nov 2025
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    Coro1A and TRIM67 collaborate in netrin-dependent neuronal morphogenesis
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    Memory engram synapse 3D macromolecular architecture visualized by cryoCLEM-guided cryoET
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    sciencedirect.com/science/article/pii/S0969212625004010
  19. Sep 2025
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    Anti-P antibodies that impair memory perturb hippocampal glutamatergic receptor trafficking, synapse structure and microglia
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    pmc.ncbi.nlm.nih.gov/articles/PMC12465742/
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    Slit2/Robo1 signaling constrains image stabilization responses to preserve ethologically favorable directional asymmetry
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  22. Aug 2025
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    TNFR2 contributes to synaptic potentiation failure in hippocampal synapses and memory loss in a familial Alzheimer’s disease mouse model
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    Long-term muscarinic inhibition increases intrinsic excitability through the upregulation of A-type potassium currents in cortical neurons
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    Regulation of hippocampal excitatory synapse development by the adhesion G-protein coupled receptor brain-specific angiogenesis inhibitor 2 (BAI2/ADGRB2)
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  29. May 2025
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    A critical role of Neuroligin 2 C-terminus in OCD and social behavior
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    jneurosci.org/content/45/19/e1417242025
  31. Feb 2025
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    Loss of the proton-activated chloride channel in neurons impairs AMPA receptor endocytosis and LTD via endosomal hyper-acidification
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    pmc.ncbi.nlm.nih.gov/articles/PMC11938102/
  33. Jan 2025
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    The Hao-Fountain syndrome protein USP7 regulates neuronal connectivity in the brain via a novel p53-independent ubiquitin signaling pathway
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  35. Nov 2024
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    Modulation of SNARE-dependent exocytosis in astrocytes improves neuropathology in Huntington's disease
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  37. Oct 2024
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    CTNND2 moderates the pace of synaptic maturation and links human evolution to synaptic neoteny
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    The TMEM132B-GABAA receptor complex controls alcohol actions in the brain
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  40. Sep 2024
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    Developmental refinement of the active zone nanotopography and axon wiring at the somatosensory thalamus
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    Fluorescence-Based Quantitative Synapse Analysis for Cell Type-Specific Connectomics
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  43. Jul 2024
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    Loss of the polarity protein Par3 promotes dendritic spine neoteny and enhances learning and memory
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  45. Apr 2024
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    Overexpression of α-Klotho isoforms promotes distinct Effects on BDNF-Induced Alterations in Dendritic Morphology
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  47. Feb 2024
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    Loss of GTF2I promotes neuronal apoptosis and synaptic reduction in human cellular models of neurodevelopment
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    Oxidative Stress Plays an Important Role in Glutamatergic Excitotoxicity-Induced Cochlear Synaptopathy: Implication for Therapeutic Molecules Screening
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  50. Jan 2024
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    Astrocytic TDP-43 dysregulation impairs memory by modulating antiviral pathways and interferon-inducible chemokines
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    science.org/doi/10.1126/sciadv.ade1282
  52. Dec 2023
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    Reduced lysosomal density in neuronal dendrites mediates deficits in synaptic plasticity in Huntington’s disease
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  54. Oct 2023
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    Antibody-directed extracellular proximity biotinylation reveals that Contactin-1 regulates axo-axonic innervation of axon initial segments
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    nature.com/articles/s41467-023-42273-8
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    Celf4 controls mRNA translation underlying synaptic development in the prenatal mammalian neocortex
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    ncbi.nlm.nih.gov/pmc/articles/PMC10533865/
  57. Sep 2023
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    Plk2 promotes synaptic destabilization through disruption of N-cadherin adhesion complexes during homeostatic adaptation to hyperexcitation
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15948
  59. Aug 2023
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    Large-scale survey of excitatory synapses reveals sublamina-specific and asymmetric synapse patterns in a neurodegenerative circuit
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    ncbi.nlm.nih.gov/pmc/articles/PMC10440711/
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    Platelet-derived exerkine CXCL4/platelet factor 4 rejuvenates hippocampal neurogenesis and restores cognitive function in aged mice
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    A Noelin-organized extracellular network of proteins required for constitutive and context-dependent anchoring of AMPA-receptors
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    Preserving extracellular space for high-quality optical and ultrastructural studies of whole mammalian brains
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    ncbi.nlm.nih.gov/pmc/articles/PMC10391564/
  64. Jun 2023
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    Kv7/KCNQ potassium channels in cortical hyperexcitability and juvenile seizure-related death in Ank2-mutant mice
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    Activity-dependent tau cleavage by caspase-3 promotes neuronal dysfunction and synaptotoxicity
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  67. May 2023
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    The vestibular calyceal junction is dismantled following subchronic streptomycin in rats and sensory epithelium stress in humans
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    link.springer.com/article/10.1007/s00204-023-03518-z
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    Deep proteomics identifies shared molecular pathway alterations in synapses of patients with schizophrenia and bipolar disorder and mouse model
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  70. Apr 2023
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    Astrocytic TDP-43 dysregulation impairs memory by modulating antiviral pathways and interferon-inducible chemokines
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    ncbi.nlm.nih.gov/pmc/articles/PMC10115456/
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Antibody-directed extracellular proximity biotinylation reveals Contactin-1 regulates axo-axonic innervation of axon initial segments
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    ncbi.nlm.nih.gov/pmc/articles/PMC10028829/
  73. Mar 2023
  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Asymmetric retinal direction tuning predicts optokinetic eye movements across stimulus conditions
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    ncbi.nlm.nih.gov/pmc/articles/PMC10023158/
  75. Jan 2023
  76. www.sciencedirect.com www.sciencedirect.com
    Artificial extracellular matrix scaffolds of mobile molecules enhance maturation of human stem cell-derived neurons
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    sciencedirect.com/science/article/pii/S1934590922004945
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    Development and Optimization of a Multilayer Rat Purkinje Neuron Culture
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    link.springer.com/article/10.1007/s12311-022-01510-4
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    Human cortical interneurons optimized for grafting specifically integrate, abort seizures, and display prolonged efficacy without over-inhibition
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    sciencedirect.com/science/article/pii/S089662732201087X
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    Efficient generation of lower induced motor neurons by coupling Ngn2 expression with developmental cues
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    sciencedirect.com/science/article/pii/S2211124722017958
  80. Nov 2022
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    Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies
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    Development of single-molecule ubiquitination mediated fluorescence complementation to visualize protein ubiquitination dynamics in dendrites
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    sciencedirect.com/science/article/pii/S2211124722015297
  83. Oct 2022
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    Retrosplenial and subicular inputs converge on superficially projecting layer V neurons of medial entorhinal cortex
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    link.springer.com/article/10.1007/s00429-022-02578-8
  85. Aug 2022
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    Warburg-like metabolic transformation underlies neuronal degeneration in sporadic Alzheimer’s disease
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    sciencedirect.com/science/article/pii/S1550413122003138
  87. Jul 2022
  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Slitrk2 deficiency causes hyperactivity with altered vestibular function and serotonergic dysregulation
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    ncbi.nlm.nih.gov/pmc/articles/PMC9250022/
  89. Jun 2022
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    Bidirectional regulation of synaptic SUMOylation by Group 1 metabotropic glutamate receptors
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    link.springer.com/article/10.1007/s00018-022-04405-z
  91. Apr 2022
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    A presynaptic phosphosignaling hub for lasting homeostatic plasticity
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  93. Mar 2022
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    Neurons undergo pathogenic metabolic reprogramming in models of familial ALS
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    Stabilization of Spine Synaptopodin by mGluR1 Is Required for mGluR-LTD
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    jneurosci.org/content/42/9/1666
  96. Feb 2022
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    LiCl treatment leads to long-term restoration of spine maturation and synaptogenesis in adult Tbr1 mutants
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    link.springer.com/article/10.1186/s11689-022-09421-5
  98. Oct 2021
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    Multiomics of synaptic junctions reveals altered lipid metabolism and signaling following environmental enrichment
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  100. Sep 2021
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    Hippocampal overexpression of NOS1AP promotes endophenotypes related to mental disorders
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    ncbi.nlm.nih.gov/pmc/articles/PMC8403735/
  102. Aug 2021
  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Localization, proteomics, and metabolite profiling reveal a putative vesicular transporter for UDP-glucose
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    ncbi.nlm.nih.gov/pmc/articles/PMC8373376/
  104. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Synaptic Scaffolds, Ion Channels and Polyamines in Mouse Photoreceptor Synapses: Anatomy of a Signaling Complex
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    ncbi.nlm.nih.gov/pmc/articles/PMC8356055/
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    Transplantable human motor networks as a neuron-directed strategy for spinal cord injury
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    ncbi.nlm.nih.gov/pmc/articles/PMC8333163/
  106. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Presynaptic Scaffold Protein Bassoon in Forebrain Excitatory Neurons Mediates Hippocampal Circuit Maturation: Potential Involvement of TrkB Signalling
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    ncbi.nlm.nih.gov/pmc/articles/PMC8347324/
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    The Social Component of Environmental Enrichment Is a Pro-neurogenic Stimulus in Adult c57BL6 Female Mice
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    frontiersin.org/article/10.3389/fcell.2019.00062/full
  110. Jul 2021
  111. www.jneurosci.org www.jneurosci.org
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    jneurosci.org/content/34/46/15327
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    RbAp48 Protein Is a Critical Component of GPR158/OCN Signaling and Ameliorates Age-Related Memory Loss
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  113. www.nature.com www.nature.com
    Activity-dependent changes in synaptic protein complex composition are consistent in different detergents despite differential solubility
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    nature.com/articles/s41598-019-46690-y
  114. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Computational Synaptic Antibody Characterization Tool for Array Tomography
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    ncbi.nlm.nih.gov/pmc/articles/PMC6057115/
  115. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PTPσ drives excitatory presynaptic assembly via various extracellular and intracellular mechanisms
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    ncbi.nlm.nih.gov/pmc/articles/PMC6705959/
  116. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Multiple roles of afadin in the ultrastructural morphogenesis of mouse hippocampal mossy fiber synapses
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    onlinelibrary.wiley.com/doi/10.1002/cne.24238/full
  117. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Loss of SynDIG1 Reduces Excitatory Synapse Maturation But Not Formation In Vivo
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    ncbi.nlm.nih.gov/pmc/articles/PMC5073248/
  118. www.sciencedirect.com www.sciencedirect.com
    GRASP1 Regulates Synaptic Plasticity and Learning through Endosomal Recycling of AMPA Receptors
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    sciencedirect.com/science/article/pii/S0896627317301393
  119. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Regulation of Neural Circuit Development by Cadherin-11 Provides Implications for Autism
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    ncbi.nlm.nih.gov/pmc/articles/PMC8266214/
  120. link.springer.com link.springer.com
    W246G Mutant ELOVL4 Impairs Synaptic Plasticity in Parallel and Climbing Fibers and Causes Motor Defects in a Rat Model of SCA34
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    link.springer.com/article/10.1007/s12035-021-02439-1
  121. Jun 2021
  122. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Cleaved PINK1 induces neuronal plasticity through PKA-mediated BDNF functional regulation
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    onlinelibrary.wiley.com/doi/10.1002/jnr.24854
  123. May 2021
  124. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neuronal pentraxin 1: A synaptic-derived plasma biomarker in Alzheimer's disease
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    ncbi.nlm.nih.gov/pmc/articles/PMC8092920/
  125. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A photoswitchable GPCR-based opsin for presynaptic inhibition
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    ncbi.nlm.nih.gov/pmc/articles/PMC8194251/
  126. Feb 2021
  127. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Subcellular sorting of neuregulins controls the assembly of excitatory-inhibitory cortical circuits
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    ncbi.nlm.nih.gov/pmc/articles/PMC7755390/
  128. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Rapid 3D Enhanced Resolution Microscopy Reveals Diversity in Dendritic Spinule Dynamics, Regulation, and Function
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    ncbi.nlm.nih.gov/pmc/articles/PMC7879711/
  129. Nov 2020
  130. www.cell.com www.cell.com
    Synapse and Active Zone Assembly in the Absence of Presynaptic Ca2+ Channels and Ca2+ Entry
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  132. Oct 2020
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  134. Sep 2020
  135. www.embopress.org www.embopress.org
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  148. Jan 2020
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  169. Nov 2017
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