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Oct 2025
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In situ extended immune activation instantly after tumor resection by oncolytic virus controls postoperative tumor recurrence

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  DOI: 10.1016/j.xcrm.2025.102399
  
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sciencedirect.com/science/article/pii/S2666379125004720
Aug 2025
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Tumor-resident probiotic Clostridium butyricum improves aPD-1 efficacy in colorectal cancer models by inhibiting IL-6-mediated immunosuppression

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sciencedirect.com/science/article/pii/S1535610825003186
Jul 2025
52.53.155.43 52.53.155.43

1-s2.0-S2589004225014956-main-html.html

1
1. scibot 31 Jul 2025
  
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  DOI: 10.1016/j.isci.2025.113234
  
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The costimulatory molecule ICOS limits memory-like properties and function of exhausted PD-1+CD8+ T cells

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  DOI: 10.1016/j.immuni.2025.06.001
  
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sciencedirect.com/science/article/pii/S1074761325002481
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Mitochondrial complex IV remodeling in tumor-associated macrophages amplifies interferon signaling and promotes anti-tumor immunity

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sciencedirect.com/science/article/pii/S1074761325002754
Jun 2025
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Prolonged but finite antigen presentation promotes reversible defects of “helpless” memory CD8+ T cells

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1. scibot 26 Jun 2025
  
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  DOI: 10.1016/j.immuni.2025.05.025
  
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sciencedirect.com/science/article/pii/S1074761325002468
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

KMT2D coordinates antiviral CD4+ T cell responses through opposing effects on T follicular helper and cytotoxic gene expression

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  DOI: 10.1016/j.celrep.2025.115775
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12302258/
May 2025
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MCRS1 sensitizes T cell–dependent immunotherapy by augmenting MHC-I expression in solid tumors

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1. scibot 19 May 2025
  
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  DOI: 10.1084/jem.20240959
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11572484/
52.53.155.43 52.53.155.43

1-s2.0-S2589004225007692-main-html.html

1
1. scibot 18 May 2025
  
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  DOI: 10.1016/j.isci.2025.112508
  
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52.53.155.43/bf6cba30678d0d150a13cbeb68660b4f11367a41/1-s2.0-S2589004225007692-main-html.html
Apr 2025
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Tailoring an intravenously injectable oncolytic virus for augmenting radiotherapy

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1. scibot 15 Apr 2025
  
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  DOI: 10.1016/j.xcrm.2025.102078
  
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sciencedirect.com/science/article/pii/S266637912500151X
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Systemic 4-1BB stimulation augments extrafollicular memory B cell formation and recall responses during Plasmodium infection

1
1. scibot 15 Apr 2025
  
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  DOI: 10.1016/j.celrep.2025.115528
  
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sciencedirect.com/science/article/pii/S2211124725002992
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SOSTDC1 downregulation in CD4+ T cells confers protection against obesity-induced insulin resistance

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1. scibot 03 Apr 2025
  
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  DOI: 10.1016/j.celrep.2025.115496
  
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sciencedirect.com/science/article/pii/S2211124725002670
Mar 2025
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Anti-vascular endothelial growth factor treatment potentiates immune checkpoint blockade through a BAFF- and IL-12-dependent reprogramming of the TME

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1. scibot 20 Mar 2025
  
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  DOI: 10.1016/j.immuni.2025.02.017
  
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sciencedirect.com/science/article/pii/S1074761325000846
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Targeting tumor monocyte-intrinsic PD-L1 by rewiring STING signaling and enhancing STING agonist therapy

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1. scibot 11 Mar 2025
  
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  DOI: 10.1016/j.ccell.2025.02.014
  
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sciencedirect.com/science/article/pii/S1535610825000662
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Lymph node macrophages drive immune tolerance and resistance to cancer therapy by induction of the immune-regulatory cytokine IL-33

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1. scibot 07 Mar 2025
  
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  DOI: 10.1016/j.ccell.2025.02.017
  
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sciencedirect.com/science/article/pii/S1535610825000698
Feb 2025
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AKR1D1 suppresses liver cancer progression by promoting bile acid metabolism-mediated NK cell cytotoxicity

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1. scibot 27 Feb 2025
  
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  DOI: 10.1016/j.cmet.2025.01.011
  
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sciencedirect.com/science/article/pii/S1550413125000117
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Bacteria-derived 3-hydroxydodecanoic acid induces a potent anti-tumor immune response via the GPR84 receptor

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1. scibot 27 Feb 2025
  
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  DOI: 10.1016/j.celrep.2025.115357
  
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sciencedirect.com/science/article/pii/S2211124725001287
Dec 2024
www.cell.com www.cell.com

Targeting P4HA1 promotes CD8+ T cell progenitor expansion toward immune memory and systemic anti-tumor immunity

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1. scibot 29 Dec 2024
  
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  DOI: 10.1016/j.ccell.2024.12.001
  
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cell.com/cancer-cell/abstract/S1535-6108(24)00476-8
52.53.155.43 52.53.155.43

can-24-1611-html.html

3
1. scibot 19 Dec 2024
  
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  DOI: 10.1158/0008-5472.can-24-1611
  
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  DOI: 10.1158/0008-5472.can-24-1611
  
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52.53.155.43/75f09a51d2e08f557660a3e31ff8f3f3198b5c01/can-24-1611-html.html
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Elevated IL-22 as a result of stress-induced gut leakage suppresses septal neuron activation to ameliorate anxiety-like behavior

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1. scibot 10 Dec 2024
  
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  DOI: 10.1016/j.immuni.2024.11.008
  
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Interleukin-1α release during necrotic-like cell death generates myeloid-driven immunosuppression that restricts anti-tumor immunity

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1. scibot 02 Dec 2024
  
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  DOI: 10.1016/j.ccell.2024.10.014
  
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sciencedirect.com/science/article/pii/S1535610824004021
Sep 2024
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PDIA3 orchestrates effector T cell program by serving as a chaperone to facilitate the non-canonical nuclear import of STAT1 and PKM2

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1. scibot 25 Sep 2024
  
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  DOI: 10.1016/j.ymthe.2024.05.038
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11405166/
Aug 2024
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Epithelial organoid supports resident memory CD8 T cell differentiation

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  DOI: 10.1016/j.celrep.2024.114621
  
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Nuclear HMGB1 is critical for CD8 T cell IFN-γ production and anti-tumor immunity

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1. scibot 20 Aug 2024
  
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  DOI: 10.1016/j.celrep.2024.114591
  
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LAG-3 and PD-1 synergize on CD8+ T cells to drive T cell exhaustion and hinder autocrine IFN-γ-dependent anti-tumor immunity

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1. scibot 20 Aug 2024
  
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  DOI: 10.1016/j.cell.2024.07.016
  
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Oligodendrocyte precursor cell-derived exosomes combined with cell therapy promote clinical recovery by immunomodulation and gliosis attenuation

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  DOI: 10.3389/fncel.2024.1413843
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11301646/
Jul 2024
www.cell.com www.cell.com

Anti-tumor efficacy of HRS-4642 and its potential combination with proteasome inhibition in KRAS G12D-mutant cancer

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  DOI: 10.1016/j.ccell.2024.06.001
  
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cell.com/cancer-cell/abstract/S1535-6108(24)00226-5
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PARP11 inhibition inactivates tumor-infiltrating regulatory T cells and improves the efficacy of immunotherapies

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  DOI: 10.1016/j.xcrm.2024.101649
  
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sciencedirect.com/science/article/pii/S266637912400363X
Jun 2024
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Nicotinamide metabolism face-off between macrophages and fibroblasts manipulates the microenvironment in gastric cancer

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  DOI: 10.1016/j.cmet.2024.05.013
  
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May 2024
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T-bet deficiency and Hic1 induction override TGF-β-dependency in the formation of CD103+ intestine-resident memory CD8+ T cells

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1. scibot 23 May 2024
  
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  DOI: 10.1016/j.celrep.2024.114258
  
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ARID1A suppresses R-loop-mediated STING-type I interferon pathway activation of anti-tumor immunity

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1. scibot 21 May 2024
  
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  DOI: 10.1016/j.cell.2024.04.025
  
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sciencedirect.com/science/article/pii/S0092867424004513
www.biorxiv.org www.biorxiv.org

The Gut Microbiome Controls Liver Tumors via the Vagus Nerve

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1. scibot 09 May 2024
  
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  DOI: 10.1101/2024.01.23.576951
  
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biorxiv.org/content/10.1101/2024.01.23.576951v1
Mar 2024
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Adipose stem cells control obesity-induced T cell infiltration into adipose tissue

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1. scibot 19 Mar 2024
  
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  DOI: 10.1016/j.celrep.2024.113963
  
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sciencedirect.com/science/article/pii/S2211124724002912
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Bile acids modified by the intestinal microbiota promote colorectal cancer growth by suppressing CD8+ T cell effector functions

2
1. scibot 13 Mar 2024
  
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  RRID:AB_2295770
  
  DOI: 10.1016/j.immuni.2024.02.014
  
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NR4a1/2 deletion promotes accumulation of TCF1+ stem-like precursors of exhausted CD8+ T cells in the tumor microenvironment

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Lipid accumulation-mediated histone hypoacetylation drives persistent NK cell dysfunction in anti-tumor immunity

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Detection of the CD8+ T cell immune response in mice infected with OVA-Listeriamonocytogenes

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IL-27 mediates immune response of pneumococcal vaccine SPY1 through Th17 and memory CD4+T cells

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PIIS2211124723009622-html.html

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SLC38A5 aggravates DC-mediated psoriasiform skin inflammation via potentiating lysosomal acidification

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CD4+ T cells regulate sickness-induced anorexia and fat wasting during a chronic parasitic infection

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Dendritic cell ICAM-1 strengthens synapses with CD8 T cells but is not required for their early differentiation

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METTL3-mediated m6A methylation orchestrates mRNA stability and dsRNA contents to equilibrate γδ T1 and γδ T17 cells

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Loss of PBAF promotes expansion and effector differentiation of CD8+ T cells during chronic viral infection and cancer

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Platelets and mast cells promote pathogenic eosinophil recruitment during invasive fungal infection via the 5-HIAA-GPR35 ligand-receptor system

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Pyruvate metabolism controls chromatin remodeling during CD4+ T cell activation

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Tissue-resident Lachnospiraceae family bacteria protect against colorectal carcinogenesis by promoting tumor immune surveillance

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BATF2 promotes HSC myeloid differentiation by amplifying IFN response mediators during chronic infection

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The altering cellular components and function in tumor microenvironment during remissive and relapsed stages of anti-CD19 CAR T-cell treated lymphoma mice

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Lymphatic PD-L1 Expression Restricts Tumor-Specific CD8+ T-cell Responses

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NKG2D signaling shifts the balance of CD8 T cells from single cytokine- to polycytokine-producing effector cells

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P2RX7 enhances tumor control by CD8+ T cells in adoptive cell therapy

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IL-5-producing CD4+ T cells and eosinophils cooperate to enhance response to immune checkpoint blockade in breast cancer

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Vitamin B5 rewires Th17 cell metabolism via impeding PKM2 nuclear translocation

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Ischemic stroke impacts the gut microbiome, ileal epithelial and immune homeostasis

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Isolating and targeting a highly active, stochastic dendritic cell subpopulation for improved immune responses

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Gut-innervating nociceptors regulate the intestinal microbiota to promote tissue protection

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Faecalibaculum rodentium remodels retinoic acid signaling to govern eosinophil-dependent intestinal epithelial homeostasis

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Nanocarriers based on bacterial membrane materials for cancer vaccine delivery

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Interferon-γ resistance and immune evasion in glioma develop via Notch-regulated co-evolution of malignant and immune cells

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Tumor cells dictate anti-tumor immune responses by altering pyruvate utilization and succinate signaling in CD8+ T cells

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cell.com/cell-metabolism/fulltext/S1550-4131(22)00228-5
May 2022
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Spatiotemporal co-dependency between macrophages and exhausted CD8+ T cells in cancer

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Mar 2022
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Tfh-cell-derived interleukin 21 sustains effector CD8+ T cell responses during chronic viral infection

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MEK inhibition overcomes chemoimmunotherapy resistance by inducing CXCL10 in cancer cells

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A purine metabolic checkpoint that prevents autoimmunity and autoinflammation

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Nov 2021
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Insular cortex neurons encode and retrieve specific immune responses

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Mice with diverse microbial exposure histories as a model for preclinical vaccine testing

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sciencedirect.com/science/article/pii/S1931312821004637
Sep 2021
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Cognate recognition of microbial antigens defines constricted CD4+ T cell receptor repertoires in the inflamed colon

1
1. scibot 28 Sep 2021
  
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  RRID:AB_2295770
  
  DOI: 10.1016/j.immuni.2021.08.014
  
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sciencedirect.com/science/article/pii/S1074761321003460
Aug 2021
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CXCR6 positions cytotoxic T cells to receive critical survival signals in the tumor microenvironment

1
1. scibot 15 Aug 2021
  
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  RRID:AB_2295770
  
  DOI: 10.1016/j.cell.2021.07.015
  
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sciencedirect.com/science/article/pii/S0092867421008564
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The Coagulation and Immune Systems Are Directly Linked through the Activation of Interleukin-1α by Thrombin

1
1. scibot 13 Aug 2021
  
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  RRID:AB_2295770
  
  DOI: 10.1016/j.immuni.2019.03.003
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6476404/
Jul 2021
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Interferon-γ Drives Treg Fragility to Promote Anti-tumor Immunity

2
1. scibot 28 Jul 2021
  
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  AB_2295770
  
  DOI: 10.1016/j.cell.2017.05.005
  
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2. scibot 28 Jul 2021
  
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  AB_2295770
  
  DOI: 10.1016/j.cell.2017.05.005
  
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sciencedirect.com/science/article/pii/S0092867417305329
Jun 2021
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Uptake of oxidized lipids by the scavenger receptor CD36 promotes lipid peroxidation and dysfunction in CD8+ T cells in tumors

1
1. scibot 08 Jun 2021
  
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  RRID:AB_2295770
  
  DOI: 10.1016/j.immuni.2021.05.003
  
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pmc.ncbi.nlm.nih.gov/articles/PMC9273026/
May 2021
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Suppressive neutrophils require PIM1 for metabolic fitness and survival during chronic viral infection

1
1. scibot 26 May 2021
  
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  RRID:AB_2295770
  
  DOI: 10.1016/j.celrep.2021.109160
  
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sciencedirect.com/science/article/pii/S2211124721005027
Apr 2021
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TGFβ restricts expansion, survival, and function of T cells within the tuberculous granuloma

1
1. scibot 29 Apr 2021
  
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  RRID:AB_2295770
  
  DOI: 10.1016/j.chom.2021.02.005
  
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sciencedirect.com/science/article/pii/S1931312821000846
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In vivo CRISPR screening reveals nutrient signaling processes underpinning CD8+ T cell fate decisions

1
1. scibot 11 Apr 2021
  
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  RRID:AB_2295770
  
  DOI: 10.1016/j.cell.2021.02.021
  
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sciencedirect.com/science/article/pii/S0092867421001719
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Cytotoxic lymphocytes target characteristic biophysical vulnerabilities in cancer

1
1. scibot 06 Apr 2021
  
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  PE/Cy7 conjugated anti-IFNγ
  
  DOI: 10.1016/j.immuni.2021.02.020
  
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sciencedirect.com/science/article/pii/S1074761321000868
Mar 2021
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Comprehensive Profiling of an Aging Immune System Reveals Clonal GZMK+ CD8+ T Cells as Conserved Hallmark of Inflammaging

1
1. scibot 08 Mar 2021
  
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  RRID:AB_2295770
  
  DOI: 10.1016/j.immuni.2020.11.005
  
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sciencedirect.com/science/article/pii/S1074761320304921
Feb 2021
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Immunogenic Chemotherapy Enhances Recruitment of CAR-T Cells to Lung Tumors and Improves Antitumor Efficacy when Combined with Checkpoint Blockade

1
1. scibot 24 Feb 2021
  
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  RRID:AB_2295770
  
  DOI: 10.1016/j.ccell.2020.11.005
  
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cell.com/cancer-cell/abstract/S1535-6108(20)30597-3
Sep 2020
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Type I Interferons Suppress Anti-parasitic Immunity and Can Be Targeted to Improve Treatment of Visceral Leishmaniasis

1
1. scibot 10 Sep 2020
  
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  RRID:AB_2295770
  
  DOI: 10.1016/j.celrep.2020.01.099
  
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sciencedirect.com/science/article/pii/S2211124720301339
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T Cell Factor 1 Suppresses CD103+ Lung Tissue-Resident Memory T Cell Development

1
1. scibot 05 Sep 2020
  
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  RRID:AB_2295770
  
  DOI: 10.1016/j.celrep.2020.03.048
  
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sciencedirect.com/science/article/pii/S2211124720303624
Jan 2020
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UVB-Induced Tumor Heterogeneity Diminishes Immune Response in Melanoma

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2295770
  
  DOI: 10.1016/j.cell.2019.08.032
  
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sciencedirect.com/science/article/pii/S0092867419309511
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CDK7 Inhibition Potentiates Genome Instability Triggering Anti-tumor Immunity in Small Cell Lung Cancer

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2295770
  
  DOI: 10.1016/j.ccell.2019.11.003
  
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sciencedirect.com/science/article/pii/S1535610819305239
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Cancer-Cell-Intrinsic cGAS Expression Mediates Tumor Immunogenicity

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2295770
  
  DOI: 10.1016/j.celrep.2019.09.065
  
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sciencedirect.com/science/article/pii/S2211124719312628
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Proteomics of Melanoma Response to Immunotherapy Reveals Mitochondrial Dependence

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2295770
  
  DOI: 10.1016/j.cell.2019.08.012
  
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sciencedirect.com/science/article/pii/S0092867419309006
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The Intestine Harbors Functionally Distinct Homeostatic Tissue-Resident and Inflammatory Th17 Cells

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2295770
  
  DOI: 10.1016/j.immuni.2019.05.004
  
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sciencedirect.com/science/article/pii/S1074761319302249
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CD4+ T Cell Help Is Required for the Formation of a Cytolytic CD8+ T Cell Subset that Protects against Chronic Infection and Cancer

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2295770
  
  DOI: 10.1016/j.immuni.2019.10.009
  
  Resource: (BioLegend Cat# 505826, RRID:AB_2295770)
  
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sciencedirect.com/science/article/pii/S1074761319304534
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Untitled document

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2295770
  
  DOI: 10.1016/j.immuni.2018.12.015
  
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sciencedirect.com/science/article/pii/S1074761318305636
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Loss of Neurological Disease HSAN-I-Associated Gene SPTLC2 Impairs CD8+ T Cell Responses to Infection by Inhibiting T Cell Metabolic Fitness

1
1. scibot 12 Jan 2020
  
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  RRID:AB_2295770
  
  DOI: 10.1016/j.immuni.2019.03.005
  
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sciencedirect.com/science/article/pii/S1074761319300950
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Untitled document

1
1. scibot 12 Jan 2020
  
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  RRID:AB_2295770
  
  DOI: 10.1016/j.immuni.2019.03.003
  
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sciencedirect.com/science/article/pii/S1074761319300937
Nov 2018
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Lung γδ T Cells Mediate Protective Responses during Neonatal Influenza Infection that Are Associated with Type 2 Immunity

1
1. scibot 05 Nov 2018
  
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  RRID:AB_2295770
  
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sciencedirect.com/science/article/pii/S1074761318303315
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TIM-3 Regulates CD103+ Dendritic Cell Function and Response to Chemotherapy in Breast Cancer

1
1. scibot 05 Nov 2018
  
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  RRID:AB_2295770
  
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sciencedirect.com/science/article/pii/S1535610817305238
europepmc.org europepmc.org

Crucial role for T cell-intrinsic IL-18R-MyD88 signaling in cognate immune response to intracellular parasite infection.

1
1. scibot 05 Nov 2018
  
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  RRID:AB_2295770
  
  Curator: @evieth
  
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europepmc.org/articles/PMC5629024/

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