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High-resolution structures of human NHE6 and NHE9 elucidate endosomal ion and lipid interactions

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  DOI: 10.1038/s41467-026-77254-0
  
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nature.com/articles/s41467-026-77254-0
Jul 2026
elifesciences.org elifesciences.org

CROP2, a Retriever–PROPPIN complex mediating protein export from endosomes to the plasma membrane in human cells

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1. scibot 30 Jul 2026
  
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  DOI: 10.7554/eLife.109403
  
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elifesciences.org/articles/109403
54.241.53.176 54.241.53.176

huang-et-al-2025-cdk5rap3-mediated-regulation-of-lysosomal-and-er-membrane-proteins-is-pivotal-for-the-survival-and-html.html

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  DOI: 10.1152/ajpcell.00284.2025
  
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54.241.53.176/19603908de2c4d3834b600abd2d3062b6121e6b6/huang-et-al-2025-cdk5rap3-mediated-regulation-of-lysosomal-and-er-membrane-proteins-is-pivotal-for-the-survival-and-html.html
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

FAM134B-mediated ER-phagy degrades APP and suppresses Alzheimer’s disease pathology

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  DOI: 10.1038/s44318-026-00818-9
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13324857/
Jun 2026
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RRAGD p.(Ser76Leu) Variant Causes Dysregulated Expression of Muscle Development and Cytoskeleton Genes in Cardiomyocytes

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1. scibot 25 Jun 2026
  
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  DOI: 10.1096/fj.202501099RR
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13285898/
www.biorxiv.org www.biorxiv.org

Lipid transfer protein ORP3 mediates lysosomal repair via LC3B and ubiquitin-TAK1-p38 signaling

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  DOI: 10.64898/2026.06.09.731146
  
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biorxiv.org/content/10.64898/2026.06.09.731146v1
May 2026
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GPNMB is a biomarker for lysosomal dysfunction and is secreted via LRRK2-modulated lysosomal exocytosis

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  DOI: 10.1126/sciadv.adv1434
  
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science.org/doi/10.1126/sciadv.adv1434
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

BPS Publications

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  DOI: 10.1111/bph.70448
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70448
Apr 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

RBM11 drives malignant progression of bladder cancer by regulating GNPDA1-PKM2 axis

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  DOI: 10.1016/j.isci.2026.115402
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13068525/
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Selective MOSPD2-STARD3 interaction at ER contact sites governs late endosome/lysosome dynamics and cholesterol homeostasis

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  DOI: 10.64898/2026.03.30.714413
  
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biorxiv.org/content/10.64898/2026.03.30.714413v1
Jan 2026
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Differential contribution of TFE3 isoforms to cell motility and invasion

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1. scibot 31 Jan 2026
  
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  DOI: 10.1038/s44319-025-00659-3
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12852735/
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Structure of the lysosomal KICSTOR-GATOR1-SAMTOR nutrient-sensing supercomplex

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  DOI: 10.1016/j.cell.2025.12.005
  
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sciencedirect.com/science/article/pii/S0092867425014187
Nov 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

BLTP3A is associated with membranes of the late endocytic pathway and is an effector of CASM

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  DOI: 10.1038/s44318-025-00543-9
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12583604/
Oct 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

TOM1 G307D variant impairs interaction with TOLLIP, autophagosome-lysosome fusion and regulation of innate immunity

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  DOI: 10.1242/dmm.052140
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12519566/
Sep 2025
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α-Synuclein aggregates inhibit ESCRT-III through sequestration and collateral degradation

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  DOI: 10.1016/j.molcel.2025.08.022
  
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sciencedirect.com/science/article/pii/S1097276525007075
Jul 2025
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Spike-specific IgG4 generated post BNT162b2 mRNA vaccination is inhibitory when directly competing with functional IgG subclasses

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1. scibot 15 Jul 2025
  
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  DOI: 10.1016/j.celrep.2025.116000
  
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sciencedirect.com/science/article/pii/S2211124725007715
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TM9SF3 is a Golgi-resident ATG8-binding protein essential for Golgi-selective autophagy

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  DOI: 10.1016/j.devcel.2025.06.017
  
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sciencedirect.com/science/article/pii/S1534580725003727
Jun 2025
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Human genetic variation reveals FCRL3 is a lymphocyte receptor for Yersinia pestis

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  DOI: 10.1016/j.xgen.2025.100917
  
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sciencedirect.com/science/article/pii/S2666979X25001739
May 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

mTOR inhibition in Q175 Huntington’s disease model mice facilitates neuronal autophagy and mutant huntingtin clearance

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  DOI: 10.7554/eLife.104979
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12092004/
52.53.155.43 52.53.155.43

1-s2.0-S258900422500762X-main-html.html

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  DOI: 10.1016/j.isci.2025.112501
  
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52.53.155.43/051211fd69843ce043e8329b1d81a8ab51c1ada6/1-s2.0-S258900422500762X-main-html.html
Mar 2025
www.sciencedirect.com www.sciencedirect.com

Anti-inflammatory activity of Pseudomonas aeruginosa DEV phage in cystic fibrosis models

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  DOI: 10.1016/j.jcf.2025.03.001
  
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sciencedirect.com/science/article/pii/S1569199325000694
Feb 2025
52.53.155.43 52.53.155.43

1-s2.0-S2589004225002330-main-html.html

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  DOI: 10.1016/j.isci.2025.111973
  
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52.53.155.43/9fd518f4d24215762f41469f2eb605eb51f907a3/1-s2.0-S2589004225002330-main-html.html
Jan 2025
52.53.155.43 52.53.155.43

PDF-html.html

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  DOI: 10.1101/2025.01.01.630988
  
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52.53.155.43/04879393ca39922a7c00ba26ca5d51a54504677a/PDF-html.html
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Methods for Visualizing and Quantifying Cholesterol Distribution in Mammalian Cells Using Filipin and D4 Probes

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  DOI: 10.1007/978-1-0716-4318-1_8
  
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link.springer.com/protocol/10.1007/978-1-0716-4318-1_8
Nov 2024
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Decreased lipidated ApoE-receptor interactions confer protection against pathogenicity of ApoE and its lipid cargoes in lysosomes

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  DOI: 10.1016/j.cell.2024.10.027
  
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sciencedirect.com/science/article/pii/S0092867424012091
Sep 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Connexin43 promotes exocytosis of damaged lysosomes through actin remodelling

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  DOI: 10.1038/s44318-024-00177-3
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11377567/
Aug 2024
bmcbiol.biomedcentral.com bmcbiol.biomedcentral.com

The topology, structure and PE interaction of LITAF underpin a Charcot-Marie-Tooth disease type 1C

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  DOI: 10.1186/s12915-016-0332-8
  
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bmcbiol.biomedcentral.com/articles/10.1186/s12915-016-0332-8
Jun 2024
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Identifying FUS amyotrophic lateral sclerosis disease signatures in patient dermal fibroblasts

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  DOI: 10.1016/j.devcel.2024.05.011
  
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sciencedirect.com/science/article/pii/S1534580724003289
Feb 2024
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The GATOR2 complex maintains lysosomal-autophagic function by inhibiting the protein degradation of MiT/TFEs

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  DOI: 10.1016/j.molcel.2024.01.012
  
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  DOI: 10.1016/j.molcel.2024.01.012
  
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sciencedirect.com/science/article/pii/S1097276524000480
Jan 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The β Isoform of Human ATP-Binding Cassette B5 Transporter, ABCB5β, Localizes to the Endoplasmic Reticulum

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  DOI: 10.3390/ijms242115847
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10649157/
Dec 2023
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MORG1 limits mTORC1 signaling by inhibiting Rag GTPases

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  DOI: 10.1016/j.molcel.2023.11.023
  
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sciencedirect.com/science/article/pii/S1097276523009681
Oct 2023
www.biorxiv.org www.biorxiv.org

Linear ubiquitination at damaged lysosomes induces local NF-κB activation and controls cell survival

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  DOI: 10.1101/2023.10.06.560832
  
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biorxiv.org/content/10.1101/2023.10.06.560832v1
52.53.155.43 52.53.155.43

PIIS2211124723012159-html.html

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  DOI: 10.1016/j.celrep.2023.113203
  
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52.53.155.43/fd1e460e8e8b6ab47a63162cfdb2758758838ade/PIIS2211124723012159-html.html
Sep 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Salmonella enterica serovar Typhi uses two type 3 secretion systems to replicate in human macrophages and colonize humanized mice

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  DOI: 10.1128/mbio.01137-23
  
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Common Markers and Small Molecule Inhibitors in Golgi Studies

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The meiotic LINC complex component KASH5 is an activating adaptor for cytoplasmic dynein

1
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  DOI: 10.1083/jcb.202204042
  
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A micropattern-based assay to study contact inhibition of locomotion and entosis of adherent human and canine cells in vitro

1
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  DOI: 10.1016/j.xpro.2023.102186
  
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Beta-coronaviruses exploit cellular stress responses by modulating TFEB and TFE3 activity

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USP32-regulated LAMTOR1 ubiquitination impacts mTORC1 activation and autophagy induction

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MOSPD2 is an endoplasmic reticulum–lipid droplet tether functioning in LD homeostasis

1
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Targeting the MITF/APAF-1 axis as salvage therapy for MAPK inhibitors in resistant melanoma

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Loss of contact inhibition of locomotion in the absence of JAM-A promotes entotic cell engulfments

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The bacterial effector GarD shields Chlamydia trachomatis inclusions from RNF213-mediated ubiquitylation and destruction

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β-Glucocerebrosidase Deficiency Activates an Aberrant Lysosome-Plasma Membrane Axis Responsible for the Onset of Neurodegeneration

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Parkinson’s disease-risk protein TMEM175 is a proton-activated proton channel in lysosomes

1
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ER-lysosome lipid transfer protein VPS13C/PARK23 prevents aberrant mtDNA-dependent STING signaling

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Mar 2022
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Combined Therapeutics for Atherosclerosis Treatment Using Polymeric Nanovectors

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Feb 2022
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Lipid kinases VPS34 and PIKfyve coordinate a phosphoinositide cascade to regulate retriever-mediated recycling on endosomes

2
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  DOI: 10.7554/eLife.69709
  
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Oct 2021
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Lysosomal Zn2+ release triggers rapid, mitochondria-mediated, non-apoptotic cell death in metastatic melanoma

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A Brucella Type IV Effector Targets the COG Tethering Complex to Remodel Host Secretory Traffic and Promote Intracellular Replication

2
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  DOI: 10.1016/j.chom.2017.07.017
  
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Cytosolic replication in epithelial cells fuels intestinal expansion and chronic fecal shedding of Salmonella Typhimurium

1
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The Rag GTPase Regulates the Dynamic Behavior of TSC Downstream of Both Amino Acid and Growth Factor Restriction

1
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Mar 2021
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Pharmacological and genetic characterisation of the canine P2X4 receptor

1
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Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling

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Mauve/LYST limits fusion of lysosome-related organelles and promotes centrosomal recruitment of microtubule nucleating proteins

1
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  DOI: 10.1016/j.devcel.2021.02.019
  
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Feb 2021
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High‐content imaging and structure‐based predictions reveal functional differences between Niemann‐Pick C1 variants

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Jan 2021
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Golgi-Dependent Copper Homeostasis Sustains Synaptic Development and Mitochondrial Content

1
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  DOI: 10.1523/JNEUROSCI.1284-20.2020
  
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G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling

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Sep 2020
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The Protein Translocation Defect of MCT8L291R Is Rescued by Sodium Phenylbutyrate

1
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  DOI: 10.1159/000507439
  
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Internalization of trophoblastic small extracellular vesicles and detection of their miRNA cargo in P-bodies

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The GTPase Rab27b regulates the release, autophagic clearance, and toxicity of alpha-synuclein

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BPS Publications

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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15009
Jan 2020
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Untitled document

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  DOI: 10.1016/j.cub.2019.01.041
  
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The Late Endosomal Pathway Regulates the Ciliary Targeting of Tetraspanin Protein Peripherin 2

1
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  DOI: 10.1523/JNEUROSCI.2811-18.2019
  
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jneurosci.org/content/39/18/3376
Nov 2018
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Untitled document

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nature.com/articles/s41467-017-01289-7
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GRASP55 Senses Glucose Deprivation through O-GlcNAcylation to Promote Autophagosome-Lysosome Fusion

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ELMOD1 Stimulates ARF6-GTP Hydrolysis to Stabilize Apical Structures in Developing Vestibular Hair Cells

1
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jneurosci.org/content/38/4/843
Nov 2017
elifesciences.org elifesciences.org

Multiplex image-based autophagy RNAi screening identifies SMCR8 as ULK1 kinase activity and gene expression regulator

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1. scibot 08 Nov 2017
  
  in Public
  
  AB_2296838
  
  Curator: @kaitlinsung
  
  Resource used:
  
  (DSHB Cat# h4a3, RRID:AB_2296838)
  
  SciCrunch record: RRID:AB_2296838
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:AB_2296838 RRIDCUR:Validated
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RRID:AB_2296838

RRIDCUR:Validated

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scibot

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elifesciences.org/articles/23063
bmcbiol.biomedcentral.com bmcbiol.biomedcentral.com

The topology, structure and PE interaction of LITAF underpin a Charcot-Marie-Tooth disease type 1C

1
1. scibot 08 Nov 2017
  
  in Public
  
  AB_2296838
  
  Curator: @gabimpine
  
  Resource used:
  
  (DSHB Cat# h4a3, RRID:AB_2296838)
  
  SciCrunch record: RRID:AB_2296838
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:AB_2296838 RRIDCUR:Validated
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RRID:AB_2296838

RRIDCUR:Validated

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scibot

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bmcbiol.biomedcentral.com/articles/10.1186/s12915-016-0332-8

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