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Deletion of Mfn2 in endothelial cells triggers a mitohormetic response that improves systemic metabolism and healthspan in mice

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  DOI: 10.1016/j.cmet.2026.01.012
  
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sciencedirect.com/science/article/pii/S1550413126000124
Feb 2026
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Tumor-immune-neural circuit disrupts energy homeostasis in cancer cachexia

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sciencedirect.com/science/article/pii/S153561082600053X
Jan 2026
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Ccl12 coordinates immune-neural crosstalk to promote adipose sympathetic remodeling after burn trauma

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1. scibot 29 Jan 2026
  
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  DOI: 10.1016/j.celrep.2025.116921
  
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DGAT-driven futile lipid cycling has a pronounced, yet concealed, thermogenic function

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sciencedirect.com/science/article/pii/S1550413125005406
Nov 2025
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jaeckstein-et-al-2025-purinergic-adipocyte-macrophage-crosstalk-promotes-degeneration-of-thermogenic-brown-adipose-html.html

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54.241.53.176/f747cb2da22a4018614419251bb372fb2280d9d1/jaeckstein-et-al-2025-purinergic-adipocyte-macrophage-crosstalk-promotes-degeneration-of-thermogenic-brown-adipose-html.html
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Blocking glycogen synthase 1 in white adipose tissue alleviates hypermetabolism following severe burn injury through inhibition of JAK2 by UDPG

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sciencedirect.com/science/article/pii/S221112472501349X
Oct 2025
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Nuclear hormone-sensitive lipase regulates adipose tissue mass and adipocyte metabolism

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sciencedirect.com/science/article/pii/S1550413125004334
Jul 2025
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matienzo-et-al-2025-adipocyte-specific-modulation-of-11β-hsd-enzymes-for-the-treatment-of-obesity-in-male-mice-html.html

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  DOI: 10.6084/m9.figshare.29333861
  
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52.53.155.43/0eec343059498565fba813ed54e166140d5ee93f/matienzo-et-al-2025-adipocyte-specific-modulation-of-11β-hsd-enzymes-for-the-treatment-of-obesity-in-male-mice-html.html
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The impact of neuregulin 4 on metabolic dysregulation in lipodystrophy

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pmc.ncbi.nlm.nih.gov/articles/PMC12236340/
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AGPAT3 deficiency impairs adipocyte differentiation and leads to a lean phenotype in mice

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1. scibot 02 Jul 2025
  
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  DOI: 10.1152/ajpendo.00012.2024
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11390115/
Jun 2025
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Interferon-tau infusion into the ovine corpus luteum delays luteolysis

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1. scibot 11 Jun 2025
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12097895/
May 2025
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Growth Hormone Promotes Lipolysis and Impairs Insulin Sensitivity by Activating the ERK/HSL Signaling Pathway in Bovine Adipocytes

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1. scibot 16 May 2025
  
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  DOI: 10.1002/aro2.70015
  
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onlinelibrary.wiley.com/doi/10.1002/aro2.70015
Apr 2025
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Protocol to study inter-tissue communication between the hypothalamus and white adipose tissue and lifespan using a chemogenetic approach in aged mice

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1. scibot 07 Apr 2025
  
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  DOI: 10.1016/j.xpro.2024.103551
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11969402/
Mar 2025
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Inhibition of basal IL-6 activity promotes subcutaneous fat retention in humans during fasting and postprandial states

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1. scibot 29 Mar 2025
  
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  DOI: 10.1016/j.xcrm.2025.102042
  
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sciencedirect.com/science/article/pii/S2666379125001156
Feb 2025
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An organism-level quantitative flux model of energy metabolism in mice

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1. scibot 21 Feb 2025
  
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  DOI: 10.1016/j.cmet.2025.01.008
  
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sciencedirect.com/science/article/pii/S1550413125000087
Dec 2024
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1-s2.0-S2589004224027895-main-html.html

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1. scibot 12 Dec 2024
  
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  DOI: 10.1016/j.isci.2024.111562
  
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52.53.155.43/115051ad15f7831b34f4faf1916680a9b8fdaa42/1-s2.0-S2589004224027895-main-html.html
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Thyroid hormones are required for thermogenesis of beige adipocytes induced by Zfp423 inactivation

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1. scibot 02 Dec 2024
  
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  DOI: 10.1016/j.celrep.2024.114987
  
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sciencedirect.com/science/article/pii/S221112472401338X
Sep 2024
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Adipose ADM2 ameliorates NAFLD via promotion of ceramide catabolism

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1. scibot 17 Sep 2024
  
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  DOI: 10.1016/j.apsb.2024.09.010
  
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sciencedirect.com/science/article/pii/S2211383524003733
Aug 2024
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Growth differentiation factor 15 alleviates diastolic dysfunction in mice with experimental diabetic cardiomyopathy

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  DOI: 10.1016/j.celrep.2024.114573
  
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cell.com/cell-reports/abstract/S2211-1247(24)00902-1
Jul 2024
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Lipid-associated macrophages reshape BAT cell identity in obesity

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1. scibot 18 Jul 2024
  
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sciencedirect.com/science/article/pii/S2211124724007769
Jun 2024
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BPS Publications

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  DOI: 10.1111/bph.16436
  
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bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.16436
Apr 2024
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α2δ1-mediated maladaptive sensory plasticity disrupts adipose tissue homeostasis following spinal cord injury

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sciencedirect.com/science/article/pii/S2666379124001940
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Adipocyte PI3K links adipostasis with baseline insulin secretion at fasting through an adipoincretin effect

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1. scibot 24 Apr 2024
  
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Standardized In Vitro Models of Human Adipose Tissue Reveal Metabolic Flexibility in Brown Adipocyte Thermogenesis

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1. scibot 23 Apr 2024
  
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  DOI: 10.1210/endocr/bqad161
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11032247/
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Creatine and low-dose lithium supplementation separately alter energy expenditure, body mass and adipose metabolism for the promotion of thermogenesis

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ncbi.nlm.nih.gov/pmc/articles/PMC10973579/
Jan 2024
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DMHPpp1r17 neurons regulate aging and lifespan in mice through hypothalamic-adipose inter-tissue communication

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  DOI: 10.1016/j.cmet.2023.12.011
  
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sciencedirect.com/science/article/pii/S155041312300462X
Oct 2023
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Adipocyte Subpopulations Mediate Growth Hormone-induced Lipolysis and Glucose Tolerance in Male Mice

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1. scibot 31 Oct 2023
  
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  DOI: 10.1210/endocr/bqad151
  
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academic.oup.com/endo/article-abstract/164/11/bqad151/7332055
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bqad147-html.html

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  DOI: 10.1210/endocr/bqad147
  
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52.53.155.43/e290076365f3caac1d7269bf72d171e5e569498f/bqad147-html.html
Aug 2023
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Luteal Lipid Droplets: A Novel Platform for Steroid Synthesis

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  DOI: 10.1210/endocr/bqad124
  
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dx.doi.org/10.1210/endocr/bqad124
May 2023
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The effects of caloric restriction on adipose tissue and metabolic health are sex- and age-dependent

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1. scibot 12 May 2023
  
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  DOI: 10.7554/eLife.88080
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10171869/
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Opioid growth factor receptor promotes adipose tissue thermogenesis via enhancing lipid oxidation

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  DOI: 10.1093/lifemeta/load018
  
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52.53.155.43/114e5b064461e16a4c14e5a8e7760094e7597154/load018-html.html
Jan 2023
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BPS Publications

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1. scibot 14 Jan 2023
  
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  DOI: 10.1111/bph.15979
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15979
Oct 2022
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The rheumatoid arthritis drug auranofin lowers leptin levels and exerts antidiabetic effects in obese mice

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  DOI: 10.1016/j.cmet.2022.09.019
  
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sciencedirect.com/science/article/pii/S1550413122004090
Aug 2022
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The matricellular protein SPARC induces inflammatory interferon-response in macrophages during aging

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1. scibot 13 Aug 2022
  
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  DOI: 10.1016/j.immuni.2022.07.007
  
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sciencedirect.com/science/article/pii/S1074761322003405
Jun 2022
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In vitro analyses of paracrine effects of murine classically activated macrophage on beige adipocyte metabolism

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1. scibot 22 Jun 2022
  
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A mechanosensitive lipolytic factor in the bone marrow promotes osteogenesis and lymphopoiesis

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Acute deletion of the FOXO1-dependent hepatokine FGF21 does not alter basal glucose homeostasis or lipolysis in mice

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A macrophage-hepatocyte glucocorticoid receptor axis coordinates fasting ketogenesis

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FGF1 and insulin control lipolysis by convergent pathways

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Brown adipocyte ATF4 activation improves thermoregulation and systemic metabolism

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The thermogenic activity of adjacent adipocytes fuels the progression of ccRCC and compromises anti-tumor therapeutic efficacy

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Spatial mapping reveals human adipocyte subpopulations with distinct sensitivities to insulin

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Regulation of UCP1 and Mitochondrial Metabolism in Brown Adipose Tissue by Reversible Succinylation

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Mitochondrial cristae-remodeling protein OPA1 in POMC neurons couples Ca2+ homeostasis with adipose tissue lipolysis

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C1q/TNF-related protein 2 (CTRP2) deletion promotes adipose tissue lipolysis and hepatic triglyceride secretion

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Vascular Endothelial Growth Factor–D (VEGF-D) Overexpression and Lymphatic Expansion in Murine Adipose Tissue Improves Metabolism in Obesity

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Microbiota Depletion Impairs Thermogenesis of Brown Adipose Tissue and Browning of White Adipose Tissue

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Lipolysis drives expression of the constitutively active receptor GPR3 to induce adipose thermogenesis

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Contrasting recruitment of skin-associated adipose depots during cold challenge of mouse and human

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Hepatic AKT orchestrates adipose tissue thermogenesis via FGF21-dependent and -independent mechanisms

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Levels of β-klotho determine the thermogenic responsiveness of adipose tissues: involvement of the autocrine action of FGF21

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Plasmalogen attenuates the development of hepatic steatosis and cognitive deficit through mechanism involving p75NTR inhibition

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Identification of ALK in Thinness

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Hypothalamic bile acid-TGR5 signaling protects from obesity

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The phytochemical hyperforin triggers thermogenesis in adipose tissue via a Dlat-AMPK signaling axis to curb obesity

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PKA and AMPK Signaling Pathways Differentially Regulate Luteal Steroidogenesis

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Hormone-sensitive lipase couples intergenerational sterol metabolism to reproductive success

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An AMPK-dependent, non-canonical p53 pathway plays a key role in adipocyte metabolic reprogramming

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Loss of Muscle Carnitine Palmitoyltransferase 2 Prevents Diet-Induced Obesity and Insulin Resistance despite Long-Chain Acylcarnitine Accumulation

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Homocysteine promotes hepatic steatosis by activating the adipocyte lipolysis in a HIF1α-ERO1α-dependent oxidative stress manner

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Sex-specific effects of α2δ–1 in the ventromedial hypothalamus of female mice controlling glucose and lipid balance

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Human Bone Marrow Is Comprised of Adipocytes with Specific Lipid Metabolism

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Spatiotemporal contact between peroxisomes and lipid droplets regulates fasting-induced lipolysis via PEX5

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Atrial Natriuretic Peptide Orchestrates a Coordinated Physiological Response to Fuel Non-shivering Thermogenesis

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A Mouse Homolog of a Human TP53 Germline Mutation Reveals a Lipolytic Activity of p53

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Non-canonical mTORC2 Signaling Regulates Brown Adipocyte Lipid Catabolism through SIRT6-FoxO1

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Thyroid-Hormone-Induced Browning of White Adipose Tissue Does Not Contribute to Thermogenesis and Glucose Consumption

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A Receptor of the Immunoglobulin Superfamily Regulates Adaptive Thermogenesis

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TAZ Is a Negative Regulator of PPARγ Activity in Adipocytes and TAZ Deletion Improves Insulin Sensitivity and Glucose Tolerance

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Tanycytes Regulate Lipid Homeostasis by Sensing Free Fatty Acids and Signaling to Key Hypothalamic Neuronal Populations via FGF21 Secretion

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Dopamine Signaling in the Suprachiasmatic Nucleus Enables Weight Gain Associated with Hedonic Feeding

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Aging Induces an Nlrp3 Inflammasome-Dependent Expansion of Adipose B Cells That Impairs Metabolic Homeostasis

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TNF‐α Upregulates IKKε Expression via the Lin28B/let‐7a Pathway to Induce Catecholamine Resistance in Adipocytes

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Mature Human White Adipocytes Cultured under Membranes Maintain Identity, Function, and Can Transdifferentiate into Brown-like Adipocytes

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GPS2 Deficiency Triggers Maladaptive White Adipose Tissue Expansion in Obesity via HIF1A Activation

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Glucocorticoid-Induced Metabolic Disturbances Are Exacerbated in Obese Male Mice

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Divergent Role of Estrogen-Related Receptor α in Lipid- and Fasting-Induced Hepatic Steatosis in Mice

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Male Brown Fat–Specific Double Knockout of IGFIR/IR: Atrophy, Mitochondrial Fission Failure, Impaired Thermogenesis, and Obesity

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Lipolysis in Brown Adipocytes Is Not Essential for Cold-Induced Thermogenesis in Mice

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Brown Fat AKT2 Is a Cold-Induced Kinase that Stimulates ChREBP-Mediated De Novo Lipogenesis to Optimize Fuel Storage and Thermogenesis

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Neurosecretory protein GL stimulates food intake, de novo lipogenesis, and onset of obesity

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A Hypothalamic Phosphatase Switch Coordinates Energy Expenditure with Feeding

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Endogenous Calcitonin Gene-Related Peptide Regulates Lipid Metabolism and Energy Homeostasis in Male Mice

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Hypoxia-Inducible Lipid Droplet–Associated Is Not a Direct Physiological Regulator of Lipolysis in Adipose Tissue

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