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A Nanoparticle-Integrated Complete Manufacturing Pipeline of Chemically Engineered Exosomes

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1. scibot 31 Mar 2026
  
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  DOI: 10.1002/advs.202516075
  
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advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202516075
Mar 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

MYCT1–IFITM2/3 interaction links endothelial endolysosomal trafficking to white adipose tissue expansion

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1. scibot 27 Mar 2026
  
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  DOI: 10.1084/jem.20251497
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13016079/
Dec 2025
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Annexin A7 enhances TIA1 axonal trafficking to counteract pathological aggregation in neurons

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1. scibot 18 Dec 2025
  
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  DOI: 10.1038/s44318-025-00609-8
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12706091/
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BPS Publications

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1. scibot 06 Dec 2025
  
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  DOI: 10.1111/bph.70258
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70258
Jul 2025
52.53.155.43 52.53.155.43

2025.07.14.664742v1.full-html.html

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1. scibot 25 Jul 2025
  
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  DOI: 10.1101/2025.07.14.664742
  
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52.53.155.43/0ddeb0d5c1e9d78409db30015477d90afb34bbce/2025.07.14.664742v1.full-html.html
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EPLINα controls integrin recycling from Rab21 endosomes to drive breast cancer cell migration

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1. scibot 16 Jul 2025
  
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  DOI: 10.1016/j.devcel.2025.06.025
  
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sciencedirect.com/science/article/pii/S1534580725004034
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TNF-α-NF-κB activation through pathological α-Synuclein disrupts the BBB and exacerbates axonopathy

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1. scibot 15 Jul 2025
  
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  DOI: 10.1016/j.celrep.2025.116001
  
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sciencedirect.com/science/article/pii/S2211124725007727
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Interconnections of insulin/IGF-1 signaling and autophagy abnormalities in Alzheimer's disease

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1. scibot 08 Jul 2025
  
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  DOI: 10.1002/alz.70099
  
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alz-journals.onlinelibrary.wiley.com/doi/10.1002/alz.70099
Jun 2025
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Cytokine-induced reprogramming of human macrophages toward Alzheimer’s disease-relevant molecular and cellular phenotypes in vitro

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1. scibot 26 Jun 2025
  
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  DOI: 10.1016/j.celrep.2025.115909
  
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sciencedirect.com/science/article/pii/S2211124725006801
May 2025
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Disrupted endosomal trafficking of the Vangl-Celsr polarity complex underlies congenital anomalies in Xenopus trachea-esophageal morphogenesis

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1. scibot 29 May 2025
  
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  DOI: 10.1016/j.devcel.2025.04.026
  
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sciencedirect.com/science/article/pii/S1534580725002862
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Glycerophospholipid metabolism licenses IgE-mediated mast cell degranulation

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1. scibot 22 May 2025
  
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  DOI: 10.1016/j.celrep.2025.115742
  
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sciencedirect.com/science/article/pii/S2211124725005133
Apr 2025
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SLIRP amplifies antiviral signaling via positive feedback regulation and contributes to autoimmune diseases

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1. scibot 24 Apr 2025
  
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  DOI: 10.1016/j.celrep.2025.115588
  
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sciencedirect.com/science/article/pii/S2211124725003596
Mar 2025
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PTPσ-mediated PI3P regulation modulates neurodegeneration in C9ORF72-ALS/FTD

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1. scibot 13 Mar 2025
  
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  DOI: 10.1016/j.neuron.2025.02.005
  
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sciencedirect.com/science/article/pii/S0896627325001187
Feb 2025
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BACE1-dependent cleavage of GABAA receptor contributes to neural hyperexcitability and disease progression in Alzheimer’s disease

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1. scibot 27 Feb 2025
  
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  DOI: 10.1016/j.neuron.2025.01.030
  
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sciencedirect.com/science/article/pii/S0896627325000789
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PI3KC2β depletion rescues endosomal trafficking defects in Mtm1 knockout skeletal muscle cells

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1. scibot 19 Feb 2025
  
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  DOI: 10.1016/j.jlr.2025.100756
  
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sciencedirect.com/science/article/pii/S0022227525000161
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Loss of the proton-activated chloride channel in neurons impairs AMPA receptor endocytosis and LTD via endosomal hyper-acidification

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1. scibot 13 Feb 2025
  
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  DOI: 10.1016/j.celrep.2025.115302
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11938102/
Jan 2025
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A forward genetic screen identifies potassium channel essentiality in SHH medulloblastoma maintenance

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1. scibot 28 Jan 2025
  
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  DOI: 10.1016/j.devcel.2025.01.001
  
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sciencedirect.com/science/article/pii/S1534580725000012
Sep 2024
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Systems mapping of bidirectional endosomal transport through the crowded cell

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1. scibot 17 Sep 2024
  
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  DOI: 10.1016/j.cub.2024.08.026
  
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sciencedirect.com/science/article/pii/S0960982224011382
Aug 2024
www.embopress.org www.embopress.org

Amino acid starvation-induced LDLR trafficking accelerates lipoprotein endocytosis and LDL clearance

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1. scibot 02 Aug 2024
  
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  DOI: 10.15252/embr.202153373
  
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embopress.org/doi/full/10.15252/embr.202153373
Jul 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Rapid iPSC inclusionopathy models shed light on formation, consequence, and molecular subtype of α-synuclein inclusions

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1. scibot 30 Jul 2024
  
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  DOI: 10.1016/j.neuron.2024.06.002
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11377155/
May 2024
onlinelibrary.wiley.com onlinelibrary.wiley.com

Myosin phosphatase targeting subunit1 controls localization and motility of Rab7-containing vesicles: Is myosin phosphatase a cytoplasmic dynein regulator?

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1. scibot 09 May 2024
  
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  DOI: 10.1002/cm.21871
  
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onlinelibrary.wiley.com/doi/10.1002/cm.21871
Feb 2024
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Alternative polyadenylation determines the functional landscape of inverted Alu repeats

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  DOI: 10.1016/j.molcel.2024.01.008
  
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sciencedirect.com/science/article/pii/S1097276524000091
Jan 2024
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Single-molecule imaging of stochastic interactions that drive dynein activation and cargo movement in cells

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1. scibot 23 Jan 2024
  
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  DOI: 10.1083/jcb.202210026
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10798859/
www.jneurosci.org www.jneurosci.org

Nascent Aβ42 Fibrillization in Synaptic Endosomes Precedes Plaque Formation in a Mouse Model of Alzheimer's-like β-Amyloidosis

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1. scibot 02 Jan 2024
  
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  DOI: 10.1523/JNEUROSCI.1318-23.2023
  
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jneurosci.org/content/43/50/8812
Aug 2023
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Two RNA-binding proteins mediate the sorting of miR223 from mitochondria into exosomes

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1. scibot 10 Aug 2023
  
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  DOI: 10.7554/eLife.85878
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10403255/
Jun 2023
www.thelancet.com www.thelancet.com

Juvenile CLN3 disease is a lysosomal cholesterol storage disorder: similarities with Niemann-Pick type C disease

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1. scibot 01 Jun 2023
  
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  DOI: 10.1016/j.ebiom.2023.104628
  
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thelancet.com/journals/ebiom/article/PIIS2352-3964(23)00193-7/abstract
Mar 2023
www.biorxiv.org www.biorxiv.org

Two RNA-binding proteins mediate the sorting of miR223 from mitochondria into exosomes

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1. scibot 08 Mar 2023
  
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  DOI: 10.1101/2023.01.11.523558
  
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biorxiv.org/content/10.1101/2023.01.11.523558v1
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H2-induced transient upregulation of phospholipids with suppression of energy metabolism

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1. scibot 05 Mar 2023
  
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  DOI: 10.4103/2045-9912.344973
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9979205/
Feb 2023
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GPR143 controls ESCRT-dependent exosome biogenesis and promotes cancer metastasis

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  DOI: 10.1016/j.devcel.2023.01.006
  
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sciencedirect.com/science/article/pii/S1534580723000370
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Transcriptome, proteome, and protein synthesis within the intracellular cytomatrix

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  DOI: 10.1016/j.isci.2023.105965
  
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sciencedirect.com/science/article/pii/S2589004223000421
Aug 2022
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Mitochondrial double-stranded RNAs govern the stress response in chondrocytes to promote osteoarthritis development

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1. scibot 10 Aug 2022
  
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  DOI: 10.1016/j.celrep.2022.111178
  
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sciencedirect.com/science/article/pii/S2211124722009913
Jul 2022
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Rapid macropinocytic transfer of α-synuclein to lysosomes

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1. scibot 27 Jul 2022
  
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  DOI: 10.1016/j.celrep.2022.111102
  
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sciencedirect.com/science/article/pii/S2211124722009044
Aug 2021
elifesciences.org elifesciences.org

Untitled document

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1. scibot 12 Aug 2021
  
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  DOI: 10.7554/eLife.31326
  
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elifesciences.org/articles/31326
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Untitled document

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1. scibot 10 Aug 2021
  
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  DOI: 10.7554/eLife.31326
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5780041/
Jul 2021
elifesciences.org elifesciences.org

A potent voltage-gated calcium channel inhibitor engineered from a nanobody targeted to auxiliary CaVβ subunits

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1. scibot 29 Jul 2021
  
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  Anti-Rab5
  
  DOI: 10.7554/eLife.49253
  
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elifesciences.org/articles/49253
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Complex Formation between VEGFR2 and the β2-Adrenoceptor

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1. scibot 29 Jul 2021
  
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  DOI: 10.1016/j.chembiol.2019.02.014
  
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COMMD5/HCaRG Hooks Endosomes on Cytoskeleton and Coordinates EGFR Trafficking

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Oncogene-regulated release of extracellular vesicles

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Systematic Functional Analysis of SARS-CoV-2 Proteins Uncovers Viral Innate Immune Antagonists and Remaining Vulnerabilities

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Neuroprotective activity of ursodeoxycholic acid in CHMP2BIntron5 models of frontotemporal dementia

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Distribution and localization of phosphatidylinositol 5‐phosphate, 4‐kinase alpha and beta in the brain

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G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling

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Gpr37l1/prosaposin receptor regulates Ptch1 trafficking, Shh production, and cell proliferation in cerebellar primary astrocytes

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Fluorescent secreted bacterial effectors reveal active intravacuolar proliferation of Listeria monocytogenes in epithelial cells

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Endolysosomal Targeting of Mitochondria Is Integral to BAX-Mediated Mitochondrial Permeabilization during Apoptosis Signaling

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Neuronal BIN1 Regulates Presynaptic Neurotransmitter Release and Memory Consolidation

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Internalization of trophoblastic small extracellular vesicles and detection of their miRNA cargo in P-bodies

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Chimeric Antigen Receptor Designed to Prevent Ubiquitination and Downregulation Showed Durable Antitumor Efficacy

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Histones, DNA, and Citrullination Promote Neutrophil Extracellular Trap Inflammation by Regulating the Localization and Activation of TLR4

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Neuroprotective activity of ursodeoxycholic acid in CHMP2BIntron5 models of frontotemporal dementia

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Immune Sensing of Synthetic, Bacterial, and Protozoan RNA by Toll-like Receptor 8 Requires Coordinated Processing by RNase T2 and RNase 2

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BPS Publications

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A Large Panel of Isogenic APP and PSEN1 Mutant Human iPSC Neurons Reveals Shared Endosomal Abnormalities Mediated by APP β-CTFs, Not Aβ

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Flotillins promote T cell receptor sorting through a fast Rab5–Rab11 endocytic recycling axis

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  DOI: 10.1038/s41467-019-12352-w
  
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Lipocalin-2 Regulates Epidermal Growth Factor Receptor Intracellular Trafficking

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Untitled document

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A conserved major facilitator superfamily member orchestrates a subset of O-glycosylation to aid macrophage tissue invasion

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ncbi.nlm.nih.gov/pmc/articles/PMC6435326/
Nov 2018
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Vascular and Neurogenic Rejuvenation in Aging Mice by Modulation of ASM

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PKR Senses Nuclear and Mitochondrial Signals by Interacting with Endogenous Double-Stranded RNAs

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EMT Subtype Influences Epithelial Plasticity and Mode of Cell Migration

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ELMOD1 Stimulates ARF6-GTP Hydrolysis to Stabilize Apical Structures in Developing Vestibular Hair Cells

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Atg5 Disassociates the V1V0-ATPase to Promote Exosome Production and Tumor Metastasis Independent of Canonical Macroautophagy

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The endosomal neuronal proteins Nsg1/NEEP21 and Nsg2/P19 are itinerant, not resident proteins of dendritic endosomes

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