51 Matching Annotations
  1. Jun 2024
  2. www.sciencedirect.com www.sciencedirect.com
    The interaction between RIPK1 and FADD controls perinatal lethality and inflammation
    1
    1. scibot 21 Jun 2024
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      DOI: 10.1016/j.celrep.2024.114335

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    sciencedirect.com/science/article/pii/S2211124724006636
  3. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hippo-PKCζ-NFκB signaling axis: A druggable modulator of chondrocyte responses to mechanical stress
    1
    1. scibot 03 Jun 2024
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      DOI: 10.1016/j.isci.2024.109983

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    ncbi.nlm.nih.gov/pmc/articles/PMC11140209/
  4. May 2024
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    A RIPK1-specific PROTAC degrader achieves potent antitumor activity by enhancing immunogenic cell death
    1
    1. scibot 24 May 2024
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    sciencedirect.com/science/article/pii/S1074761324002309
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    The RIPK1 death domain restrains ZBP1- and TRIF-mediated cell death and inflammation
    1
    1. scibot 14 May 2024
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    sciencedirect.com/science/article/pii/S1074761324002218
  7. Apr 2024
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Edaravone Dexborneol mitigates pathology in animal and cell culture models of Alzheimer’s disease by inhibiting neuroinflammation and neuronal necroptosis
    1
    1. scibot 30 Apr 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11056062/
  9. Mar 2024
  10. 52.53.155.43 52.53.155.43
    NLRP6 induces RIP1 kinase-dependent necroptosis via TAK1-mediated p38MAPK/MK2 phosphorylation in S. Typhimurium infection
    1
    1. scibot 08 Mar 2024
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    52.53.155.43/edc059b1f8d2daaa9b02a6bfc9253e0bab800af6/1-s2.0-S2589004224005601-main-html.html
  11. Feb 2024
  12. www.sciencedirect.com www.sciencedirect.com
    PHLDA2-mediated phosphatidic acid peroxidation triggers a distinct ferroptotic response during tumor suppression
    1
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    sciencedirect.com/science/article/pii/S1550413124000056
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Osimertinib covalently binds to CD34 and eliminates myeloid leukemia stem/progenitor cells
    1
    1. scibot 03 Feb 2024
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      DOI: 10.1158/0008-5472.CAN-23-1632

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    ncbi.nlm.nih.gov/pmc/articles/PMC10831336/
  14. Jan 2024
  15. www.sciencedirect.com www.sciencedirect.com
    PARP5A and RNF146 phase separation restrains RIPK1-dependent necroptosis
    1
    1. scibot 25 Jan 2024
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      DOI: 10.1016/j.molcel.2023.12.041

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    sciencedirect.com/science/article/pii/S1097276523011218
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    Lymph node and tumor-associated PD-L1+ macrophages antagonize dendritic cell vaccines by suppressing CD8+ T cells
    1
    1. scibot 19 Jan 2024
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      DOI: 10.1016/j.xcrm.2023.101377

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    sciencedirect.com/science/article/pii/S2666379123006067
  17. Dec 2023
  18. www.sciencedirect.com www.sciencedirect.com
    Analysis of multiple programmed cell death-related prognostic genes and functional validations of necroptosis-associated genes in oesophageal squamous cell carcinoma
    1
    1. scibot 16 Dec 2023
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    sciencedirect.com/science/article/pii/S2352396423004863
  19. Nov 2023
  20. www.biorxiv.org www.biorxiv.org
    An immunohistochemical atlas of necroptotic pathway expression
    1
    1. scibot 10 Nov 2023
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      DOI: 10.1101/2023.10.31.565039

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    biorxiv.org/content/10.1101/2023.10.31.565039v1
  21. Oct 2023
  22. 52.53.155.43 52.53.155.43
    BPS Publications
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    1. scibot 06 Oct 2023
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      DOI: 10.1111/bph.16255

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    52.53.155.43/6079453bbbf12bd08872d5439d37d8b14bece994/British J Pharmacology - 2023 - Chen - DADLE promotes motor function recovery by inhibiting cytosolic phospholipase A2-html.html
  23. Sep 2023
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chronic Carbon Disulfide Exposure Induces Parkinsonian Pathology via α-Synuclein Aggregation and Necrosome Complex Interaction
    1
    1. scibot 22 Sep 2023
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      DOI: 10.1016/j.isci.2023.107787

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    ncbi.nlm.nih.gov/pmc/articles/PMC10507234/
  25. Aug 2023
  26. www.nature.com www.nature.com
    Molecular basis for nuclear accumulation and targeting of the inhibitor of apoptosis BIRC2
    1
    1. scibot 01 Aug 2023
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      DOI: 10.1038/s41594-023-01044-1

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    nature.com/articles/s41594-023-01044-1
  27. Jul 2023
  28. www.sciencedirect.com www.sciencedirect.com
    Nucleoporin Seh1 maintains Schwann cell homeostasis by regulating genome stability and necroptosis
    1
    1. scibot 21 Jul 2023
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      DOI: 10.1016/j.celrep.2023.112802

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    sciencedirect.com/science/article/pii/S2211124723008136
  29. Apr 2023
  30. www.sciencedirect.com www.sciencedirect.com
    PPDPF suppresses the development of hepatocellular carcinoma through TRIM21-mediated ubiquitination of RIPK1
    1
    1. scibot 08 Apr 2023
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      DOI: 10.1016/j.celrep.2023.112340

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    sciencedirect.com/science/article/pii/S2211124723003510
  31. Feb 2023
  32. www.sciencedirect.com www.sciencedirect.com
    Direct activation of microglia by β-glucosylceramide causes phagocytosis of neurons that exacerbates Gaucher disease
    1
    1. scibot 03 Feb 2023
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      DOI: 10.1016/j.immuni.2023.01.008

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    sciencedirect.com/science/article/pii/S1074761323000183
  33. Jan 2023
  34. www.sciencedirect.com www.sciencedirect.com
    Gasdermin D pore-forming activity is redox-sensitive
    1
    1. scibot 21 Jan 2023
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      DOI: 10.1016/j.celrep.2023.112008

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    sciencedirect.com/science/article/pii/S2211124723000190
  35. www.sciencedirect.com www.sciencedirect.com
    SPATA2 restricts OTULIN-dependent LUBAC activity independently of CYLD
    1
    1. scibot 19 Jan 2023
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      DOI: 10.1016/j.celrep.2022.111961

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    sciencedirect.com/science/article/pii/S2211124722018654
  36. Oct 2022
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SIRPα maintains macrophage homeostasis by interacting with PTK2B kinase in Mycobacterium tuberculosis infection and through autophagy and necroptosis
    1
    1. scibot 12 Oct 2022
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      DOI: 10.1016/j.ebiom.2022.104278

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    ncbi.nlm.nih.gov/pmc/articles/PMC9535427/
  38. www.sciencedirect.com www.sciencedirect.com
    Molecular mechanism of RIPK1 and caspase-8 in homeostatic type I interferon production and regulation
    1
    1. scibot 05 Oct 2022
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      DOI: 10.1016/j.celrep.2022.111434

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    sciencedirect.com/science/article/pii/S221112472201275X
  39. Aug 2022
  40. www.sciencedirect.com www.sciencedirect.com
    Mitochondrial ROS promotes susceptibility to infection via gasdermin D-mediated necroptosis
    1
    1. scibot 02 Aug 2022
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      DOI: 10.1016/j.cell.2022.06.038

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    sciencedirect.com/science/article/pii/S0092867422007905
  41. Jul 2022
  42. www.sciencedirect.com www.sciencedirect.com
    Ubiquitylation of RIPK3 beyond-the-RHIM can limit RIPK3 activity and cell death
    1
    1. scibot 08 Jul 2022
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      DOI: 10.1016/j.isci.2022.104632

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    sciencedirect.com/science/article/pii/S258900422200904X
  43. Jun 2022
  44. www.sciencedirect.com www.sciencedirect.com
    RNF31 inhibition sensitizes tumors to bystander killing by innate and adaptive immune cells
    1
    1. scibot 10 Jun 2022
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      DOI: 10.1016/j.xcrm.2022.100655

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    sciencedirect.com/science/article/pii/S2666379122001872
  45. Oct 2021
  46. www.sciencedirect.com www.sciencedirect.com
    Regulation of CYLD activity and specificity by phosphorylation and ubiquitin-binding CAP-Gly domains
    1
    1. scibot 06 Oct 2021
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      DOI: 10.1016/j.celrep.2021.109777

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    sciencedirect.com/science/article/pii/S2211124721012316
  47. Sep 2021
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CD4+ T cell-mimicking nanoparticles encapsulating DIABLO/SMAC mimetics broadly neutralize HIV-1 and selectively kill HIV-1-infected cells
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    1. scibot 18 Sep 2021
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      DOI: 10.7150/thno.59728

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    ncbi.nlm.nih.gov/pmc/articles/PMC8419049/
  49. Aug 2021
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Somatic Epigenetic Silencing of RIPK3 Inactivates Necroptosis and Contributes to Chemoresistance in Malignant Mesothelioma
    1
    1. scibot 17 Aug 2021
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      DOI: 10.1158/1078-0432.CCR-18-3683

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    ncbi.nlm.nih.gov/pmc/articles/PMC7887036/
  51. www.sciencedirect.com www.sciencedirect.com
    Human TBK1 deficiency leads to autoinflammation driven by TNF-induced cell death
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    1. scibot 15 Aug 2021
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      DOI: 10.1016/j.cell.2021.07.026

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    sciencedirect.com/science/article/pii/S0092867421008850
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    Axonal Activation of the Unfolded Protein Response Promotes Axonal Regeneration Following Peripheral Nerve Injury
    1
    1. scibot 07 Aug 2021
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      DOI: 10.1016/j.neuroscience.2018.02.003

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    sciencedirect.com/science/article/pii/S0306452218301118
  53. Jul 2021
  54. www.sciencedirect.com www.sciencedirect.com
    A Dual Role of Caspase-8 in Triggering and Sensing Proliferation-Associated DNA Damage, a Key Determinant of Liver Cancer Development
    2
    1. scibot 28 Jul 2021
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      DOI: 10.1016/j.ccell.2017.08.010

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    sciencedirect.com/science/article/pii/S1535610817303549
  55. www.sciencedirect.com www.sciencedirect.com
    Axonal Activation of the Unfolded Protein Response Promotes Axonal Regeneration Following Peripheral Nerve Injury
    1
    1. scibot 27 Jul 2021
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    sciencedirect.com/science/article/pii/S0306452218301118
  56. May 2021
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A phosphorylation of RIPK3 kinase initiates an intracellular apoptotic pathway that promotes prostaglandin2α-induced corpus luteum regression
    1
    1. scibot 28 May 2021
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      DOI: 10.7554/eLife.67409

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    ncbi.nlm.nih.gov/pmc/articles/PMC8143796/
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    RIPK1 activation mediates neuroinflammation and disease progression in multiple sclerosis
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    1. scibot 12 May 2021
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      DOI: 10.1016/j.celrep.2021.109112

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    sciencedirect.com/science/article/pii/S2211124721004460
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    A Non-canonical PDK1-RSK Signal Diminishes Pro-caspase-8-Mediated Necroptosis Blockade
    1
    1. scibot 07 May 2021
      RRID:AB_2305314

      DOI: 10.1016/j.molcel.2020.09.004

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    sciencedirect.com/science/article/pii/S1097276520306122
  60. Apr 2021
  61. www.sciencedirect.com www.sciencedirect.com
    Functional Genomics In Vivo Reveal Metabolic Dependencies of Pancreatic Cancer Cells
    1
    1. scibot 29 Apr 2021
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      DOI: 10.1016/j.cmet.2020.10.017

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    sciencedirect.com/science/article/pii/S1550413120305507
  62. Dec 2020
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Synergism of TNF-α and IFN-γ Triggers Inflammatory Cell Death, Tissue Damage, and Mortality in SARS-CoV-2 Infection and Cytokine Shock Syndromes
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    1. scibot 10 Dec 2020
      RRID:AB_2305314

      DOI: 10.1016/j.cell.2020.11.025

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    ncbi.nlm.nih.gov/pmc/articles/PMC7674074/
  64. Nov 2020
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Casein kinase 1G2 suppresses necroptosis-promoted testis aging by inhibiting receptor-interacting kinase 3
    1
    1. scibot 26 Nov 2020
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      DOI: 10.7554/eLife.61564

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    ncbi.nlm.nih.gov/pmc/articles/PMC7673785/
  66. Sep 2020
  67. www.sciencedirect.com www.sciencedirect.com
    The Autophagy-Initiating Kinase ULK1 Controls RIPK1-Mediated Cell Death
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      RRID:AB_2305314

      DOI: 10.1016/j.celrep.2020.107547

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    sciencedirect.com/science/article/pii/S2211124720304575
  68. www.cell.com www.cell.com
    Survival of Single Positive Thymocytes Depends upon Developmental Control of RIPK1 Kinase Signaling by the IKK Complex Independent of NF-κB
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    1. scibot 23 Sep 2020
      RRID:AB_2305314

      DOI: 10.1016/j.immuni.2019.01.004

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    cell.com/immunity/abstract/S1074-7613(19)30004-4
  69. www.sciencedirect.com www.sciencedirect.com
    OTULIN Prevents Liver Inflammation and Hepatocellular Carcinoma by Inhibiting FADD- and RIPK1 Kinase-Mediated Hepatocyte Apoptosis
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      RRID:AB_2305314

      DOI: 10.1016/j.celrep.2020.01.028

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    sciencedirect.com/science/article/pii/S2211124720300371
  70. www.sciencedirect.com www.sciencedirect.com
    Caspase-6 Is a Key Regulator of Innate Immunity, Inflammasome Activation, and Host Defense
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    1. scibot 17 Sep 2020
      RRID:AB_2305314

      DOI: 10.1016/j.cell.2020.03.040

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    sciencedirect.com/science/article/pii/S0092867420303330
  71. www.sciencedirect.com www.sciencedirect.com
    Dysregulated Expression of the Nuclear Exosome Targeting Complex Component Rbm7 in Nonhematopoietic Cells Licenses the Development of Fibrosis
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    1. scibot 16 Sep 2020
      RRID:AB_2305314

      DOI: 10.1016/j.immuni.2020.02.007

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    sciencedirect.com/science/article/pii/S1074761320300789
  72. www.nature.com www.nature.com
    Necroptosis in head and neck squamous cell carcinoma: characterization of clinicopathological relevance and in vitro cell model
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      DOI: 10.1038/s41419-020-2538-5

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    nature.com/articles/s41419-020-2538-5
  73. www.sciencedirect.com www.sciencedirect.com
    Constitutive Interferon Attenuates RIPK1/3-Mediated Cytokine Translation
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    1. scibot 03 Sep 2020
      RRID:AB_2305314

      DOI: 10.1016/j.celrep.2019.12.073

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    sciencedirect.com/science/article/pii/S2211124719317309
  74. Jan 2020
  75. www.sciencedirect.com www.sciencedirect.com
    TAM Kinases Promote Necroptosis by Regulating Oligomerization of MLKL
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      RRID:AB_2305314

      DOI: 10.1016/j.molcel.2019.05.022

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    sciencedirect.com/science/article/pii/S1097276519303946
  76. www.sciencedirect.com www.sciencedirect.com
    O-GlcNAc Transferase Suppresses Inflammation and Necroptosis by Targeting Receptor-Interacting Serine/Threonine-Protein Kinase 3
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    1. scibot 13 Jan 2020
      RRID:AB_2305314

      DOI: 10.1016/j.immuni.2019.01.007

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    sciencedirect.com/science/article/pii/S1074761319300305
  77. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 12 Jan 2020
      RRID:AB_2305314

      DOI: 10.1016/j.immuni.2019.01.004

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    sciencedirect.com/science/article/pii/S1074761319300044
  78. Nov 2018
  79. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    sciencedirect.com/science/article/pii/S1931312818304918
  80. www.sciencedirect.com www.sciencedirect.com
    TBK1 Suppresses RIPK1-Driven Apoptosis and Inflammation during Development and in Aging
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    sciencedirect.com/science/article/pii/S0092867418309693