228 Matching Annotations
  1. Last 7 days
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    Modeling blood-brain barrier formation and cerebral cavernous malformations in human PSC-derived organoids
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    1. scibot 16 May 2024
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      DOI: 10.1016/j.stem.2024.04.019

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    sciencedirect.com/science/article/pii/S1934590924001462
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    Nr4a1 regulates cell-specific transcriptional programs in inhibitory GABAergic interneurons
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    1. scibot 16 May 2024
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      DOI: 10.1016/j.neuron.2024.03.018

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    sciencedirect.com/science/article/pii/S089662732400196X
  4. May 2024
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    Adult-Onset Deletion of ATP13A2 in Mice Induces Progressive Nigrostriatal Pathway Dopaminergic Degeneration and Lysosomal Abnormalities
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    1. scibot 10 May 2024
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      DOI: 10.1101/2024.01.25.577280

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    biorxiv.org/content/10.1101/2024.01.25.577280v1
  6. 52.53.155.43 52.53.155.43
    Host-pathogen Coadaptation by running with PAR protein
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    1. scibot 10 May 2024
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      DOI: 10.1101/2024.01.31.578330

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    Dendrite architecture determines mitochondrial distribution patterns in vivo
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    1. scibot 09 May 2024
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      DOI: 10.1016/j.celrep.2024.114190

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    sciencedirect.com/science/article/pii/S2211124724005187
  8. 52.53.155.43 52.53.155.43
    Tolerance thresholds underlie responses to DNA damage during germline development
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    1. scibot 03 May 2024
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      DOI: 10.1101/2024.01.07.574510

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  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Remote Neuronal Activation Coupled with Automated Blood Sampling to Induce and Measure Circulating Luteinizing Hormone in Mice
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    1. scibot 01 May 2024
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      DOI: 10.3791/65875

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    ncbi.nlm.nih.gov/pmc/articles/PMC11026941/
  10. Apr 2024
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    Mouse hippocampal CA1 VIP interneurons detect novelty in the environment and support recognition memory
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    1. scibot 18 Apr 2024
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      DOI: 10.1016/j.celrep.2024.114115

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    KCNJ2 inhibition mitigates mechanical injury in a human brain organoid model of traumatic brain injury
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    1. scibot 05 Apr 2024
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      DOI: 10.1016/j.stem.2024.03.004

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    Three-dimensional imaging studies in mice identify cellular dynamics of skeletal muscle regeneration
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    1. scibot 04 Apr 2024
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      DOI: 10.1016/j.devcel.2024.03.017

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    sciencedirect.com/science/article/pii/S1534580724001849
  14. Mar 2024
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    Subventricular zone stem cell niche injury is associated with intestinal perforation in preterm infants and predicts future motor impairment
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    1. scibot 29 Mar 2024
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      DOI: 10.1016/j.stem.2024.03.001

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    sciencedirect.com/science/article/pii/S1934590924000821
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    Transgenic tools targeting the basal ganglia reveal both evolutionary conservation and specialization of neural circuits in zebrafish
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    1. scibot 14 Mar 2024
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      DOI: 10.1016/j.celrep.2024.113916

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    sciencedirect.com/science/article/pii/S2211124724002444
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    Impaired cerebellar plasticity hypersensitizes sensory reflexes in SCN2A-associated ASD
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    1. scibot 07 Mar 2024
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      DOI: 10.1016/j.neuron.2024.01.029

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    sciencedirect.com/science/article/pii/S0896627324000552
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    The functional and anatomical characterization of three spinal output pathways of the anterolateral tract
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    1. scibot 01 Mar 2024
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      DOI: 10.1016/j.celrep.2024.113829

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    sciencedirect.com/science/article/pii/S2211124724001578
  19. Feb 2024
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    Impaired cerebellar plasticity hypersensitizes sensory reflexes in SCN2A-associated ASD
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    1. scibot 27 Feb 2024
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    Kin17 regulates proper cortical localization of Miranda in Drosophila neuroblasts by regulating Flfl expression
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    1. scibot 23 Feb 2024
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      DOI: 10.1016/j.celrep.2024.113823

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  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The RNA-binding protein, Imp specifies olfactory navigation circuitry and behavior in Drosophila
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    1. scibot 21 Feb 2024
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      DOI: 10.1101/2023.05.26.542522

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    ncbi.nlm.nih.gov/pmc/articles/PMC10312496/
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    Chronic Treatment with Serotonin Selective Reuptake Inhibitors Does Not Affect Regrowth of Serotonin Axons Following Amphetamine Injury in the Mouse Forebrain
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    1. scibot 18 Feb 2024
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      DOI: 10.1523/ENEURO.0444-22.2023

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    ncbi.nlm.nih.gov/pmc/articles/PMC10867722/
  24. Jan 2024
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    Glutamate inputs send prediction error of reward, but not negative value of aversive stimuli, to dopamine neurons
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      DOI: 10.1016/j.neuron.2023.12.019

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    sciencedirect.com/science/article/pii/S0896627323009790
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    Sympathetic nerve-enteroendocrine L cell communication modulates GLP-1 release, brain glucose utilization, and cognitive function
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    1. scibot 19 Jan 2024
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      DOI: 10.1016/j.neuron.2023.12.012

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    The conserved RNA-binding protein Imp is required for the specification and function of olfactory navigation circuitry in Drosophila
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    1. scibot 05 Jan 2024
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      DOI: 10.1016/j.cub.2023.12.020

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    sciencedirect.com/science/article/pii/S0960982223016755
  28. Nov 2023
  29. www.pnas.org www.pnas.org
    Molecular mechanisms controlling the biogenesis of the TGF-β signal Vg1
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    1. scibot 18 Nov 2023
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      DOI: 10.1073/pnas.2307203120

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    pnas.org/doi/abs/10.1073/pnas.2307203120
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    GABAergic-like dopamine synapses in the brain
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    1. scibot 02 Nov 2023
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      DOI: 10.1016/j.celrep.2023.113239

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    sciencedirect.com/science/article/pii/S2211124723012512
  31. Oct 2023
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    Pain and itch coding mechanisms of polymodal sensory neurons
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    1. scibot 28 Oct 2023
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      DOI: 10.1016/j.celrep.2023.113316

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    Choroid plexuses carry nodal-like cilia that undergo axoneme regression from early adult stage
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      DOI: 10.1016/j.devcel.2023.10.003

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    Melanocortin-3 receptor expression in AgRP neurons is required for normal activation of the neurons in response to energy deficiency
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    1. scibot 13 Oct 2023
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      DOI: 10.1016/j.celrep.2023.113188

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  35. 52.53.155.43 52.53.155.43
    2023.09.29.560022.full-html.html
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    1. scibot 06 Oct 2023
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      DOI: 10.1101/2023.09.29.560022

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  36. Sep 2023
  37. www.sciencedirect.com www.sciencedirect.com
    Orbitofrontal cortex conveys stimulus and task information to the auditory cortex
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    1. scibot 19 Sep 2023
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      DOI: 10.1016/j.cub.2023.08.059

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    sciencedirect.com/science/article/abs/pii/S0960982223011399
  38. Aug 2023
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Target-selective vertebrate motor axon regeneration depends on interaction with glial cells at a peripheral nerve plexus
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    1. scibot 31 Aug 2023
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      DOI: 10.1371/journal.pbio.3002223

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    ncbi.nlm.nih.gov/pmc/articles/PMC10464982/
  40. 52.53.155.43 52.53.155.43
    Stress-mediated dysregulation of the Rap1 small GTPase impairs hippocampal structure and function
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    1. scibot 19 Aug 2023
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      DOI: 10.1016/j.isci.2023.107566

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    The C9ORF72 repeat expansion alters neurodevelopment
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    1. scibot 17 Aug 2023
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      DOI: 10.1016/j.celrep.2023.112983

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    PIEZO2 in somatosensory neurons controls gastrointestinal transit
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      DOI: 10.1016/j.cell.2023.07.006

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    sciencedirect.com/science/article/pii/S0092867423007390
  43. Jul 2023
  44. www.sciencedirect.com www.sciencedirect.com
    Spatial organization and function of RNA molecules within phase-separated condensates in zebrafish are controlled by Dnd1
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      DOI: 10.1016/j.devcel.2023.06.009

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    sciencedirect.com/science/article/abs/pii/S1534580723003076
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Low-level repressive histone marks fine-tune gene transcription in neural stem cells
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      DOI: 10.7554/eLife.86127

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    ncbi.nlm.nih.gov/pmc/articles/PMC10344426/
  46. www.biorxiv.org www.biorxiv.org
    Ninein domains required for its localization, association with partners dynein and ensconsin, and microtubule organization
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      DOI: 10.1101/2023.06.22.546109

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    biorxiv.org/content/10.1101/2023.06.22.546109v2
  47. Jun 2023
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The septate junction component bark beetle is required for Drosophila intestinal barrier function and homeostasis
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      DOI: 10.1016/j.isci.2023.106901

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      DOI: 10.1016/j.isci.2023.106901

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    ncbi.nlm.nih.gov/pmc/articles/PMC10276166/
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    Bursting translation on single mRNAs in live cells
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    1. scibot 21 Jun 2023
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      DOI: 10.1016/j.molcel.2023.05.019

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    sciencedirect.com/science/article/pii/S1097276523003751
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    M1BP is an essential transcriptional activator of oxidative metabolism during Drosophila development
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    1. scibot 07 Jun 2023
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      DOI: 10.1038/s41467-023-38986-5

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    ncbi.nlm.nih.gov/pmc/articles/PMC10238438/
  51. May 2023
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Running throughout Middle-Age Keeps Old Adult-Born Neurons Wired
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    1. scibot 31 May 2023
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      DOI: 10.1523/ENEURO.0084-23.2023

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    The enteric nervous system relays psychological stress to intestinal inflammation
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    Cholinergic projections to the preBötzinger complex
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    A local subset of mesenchymal cells expressing the transcription factor Osr1 orchestrates lymph node initiation
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    Histological Analysis of a Mouse Model of the 22q11.2 Microdeletion Syndrome
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    M cell maturation and cDC activation determine the onset of adaptive immune priming in the neonatal Peyer’s patch
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  58. Apr 2023
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    Stem cell competition driven by the Axin2-p53 axis controls brain size during murine development
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  60. Mar 2023
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    MrgprA3-expressing pruriceptors drive pruritogen-induced alloknesis through mechanosensitive Piezo2 channel
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    Stem cell-based modeling and single-cell multiomics reveal gene-regulatory mechanisms underlying human skeletal development
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    Regulatory and coding sequences of TRNP1 co-evolve with brain size and cortical folding in mammals
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    A melanopsin ganglion cell subtype forms a dorsal retinal mosaic projecting to the supraoptic nucleus
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    Bulk and Mosaic Deletions of Egfr Reveal Regionally Defined Gliogenesis in the Developing Mouse Forebrain
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    Simultaneous activation of Tor and suppression of ribosome biogenesis by TRIM-NHL proteins promotes terminal differentiation
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  67. Feb 2023
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    Linking human Dead end 1 (DND1) variants to male infertility employing zebrafish embryos
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    PIKFYVE inhibition mitigates disease in models of diverse forms of ALS
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    Single-molecule imaging reveals translation-dependent destabilization of mRNAs
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  71. Jan 2023
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    Humidity sensors that alert mosquitoes to nearby hosts and egg-laying sites
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    Sex differences in the coexpression of prokineticin receptor 2 and gonadal steroids receptors in mice
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    A BORC-dependent molecular pathway for vesiculation of cell corpse phagolysosomes
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    Mechanism of kisspeptin neuron synchronization for pulsatile hormone secretion in male mice
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  76. Dec 2022
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    Regional specialization of the tongue revealed by gustatory ganglion imaging
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    Foxd1 is Required for 3d Patterning of the Kidney Interstitial Matrix
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    Connections between sister and non-sister telomeres of segregating chromatids maintain euploidy
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    Dynamic Ins2 Gene Activity Defines β-cell Maturity States
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    Adult newborn granule cells confer emotional state–dependent adaptability in memory retrieval
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  82. Nov 2022
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    Developmental spontaneous activity promotes formation of sensory domains, frequency tuning and proper gain in central auditory circuits
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    Development of single-molecule ubiquitination mediated fluorescence complementation to visualize protein ubiquitination dynamics in dendrites
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  86. Oct 2022
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    Activity-induced Cortical Glutamatergic Neuron Nascent Proteins
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    CASK loss of function differentially regulates neuronal maturation and synaptic function in human induced cortical excitatory neurons
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  89. Sep 2022
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    Dopamine activates astrocytes in prefrontal cortex via α1-adrenergic receptors
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    A proliferative to invasive switch is mediated by srGAP1 downregulation through the activation of TGF-β2 signaling
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  92. Aug 2022
  93. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Analysis of the distribution of vagal afferent projections from different peripheral organs to the nucleus of the solitary tract in rats
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    Myelin repair is fostered by the corticosteroid medrysone specifically acting on astroglial subpopulations
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    Optical Clearing and 3D Analysis Optimized for Mouse and Human Pancreata
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  96. Jul 2022
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    Recording and manipulation of the maternal oxytocin neural activities in mice
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  98. Jun 2022
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    A functional circuit formed by the autonomic nerves and myofibroblasts controls mammalian alveolar formation for gas exchange
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    Metabolic-scale gene activation screens identify SLCO2B1 as a heme transporter that enhances cellular iron availability
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    Phosphatidylinositol transfer protein/planar cell polarity axis regulates neocortical morphogenesis by supporting interkinetic nuclear migration
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    Cross-species incompatibility between a DNA satellite and the Drosophila Spartan homolog poisons germline genome integrity
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  103. May 2022
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    Cell-cycle exit and stem cell differentiation are coupled through regulation of mitochondrial activity in the Drosophila testis
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    A bidirectional switch in the Shank3 phosphorylation state biases synapses toward up- or downscaling
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    Nasally-delivered interferon-λ protects mice against infection by SARS-CoV-2 variants including Omicron
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  107. Apr 2022
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    Plasticity of neural connections underlying oxytocin-mediated parental behaviors of male mice
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    Visceral mesoderm signaling regulates assembly position and function of the Drosophila testis niche
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    Three-dimensional volume fluorescence-imaging of vascular plasticity in adipose tissues
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    Stage-specific control of oligodendrocyte survival and morphogenesis by TDP-43
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  112. Mar 2022
  113. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Chronic androgen excess in female mice does not impact luteinizing hormone pulse frequency or putative GABAergic inputs to GnRH neurons
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    The role of Even-skipped in Drosophila larval somatosensory circuit assembly
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    Visualizing cellular and tissue ultrastructure using Ten-fold Robust Expansion Microscopy (TREx)
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  116. Feb 2022
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    Hypothalamic pregnenolone mediates recognition memory in the context of metabolic disorders
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  118. Jan 2022
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    Spatial proteogenomics reveals distinct and evolutionarily conserved hepatic macrophage niches
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  120. Dec 2021
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    Role of neuropeptide neuromedin U in the nucleus accumbens shell in cocaine self-administration in male rats
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    Functional human gastrointestinal organoids can be engineered from three primary germ layers derived separately from pluripotent stem cells
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  123. Nov 2021
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    Cortical responses to touch reflect subcortical integration of LTMR signals
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  125. Oct 2021
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    Prolactin-sensitive olfactory sensory neurons regulate male preference in female mice by modulating responses to chemosensory cues
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    Synaptogenic activity of the axon guidance molecule Robo2 underlies hippocampal circuit function
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  130. Sep 2021
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    Discrete cis-acting element regulates developmentally timed gene-lamina relocation and neural progenitor competence in vivo
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    Diversity of developing peripheral glia revealed by single-cell RNA sequencing
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  133. Aug 2021
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    Cortical neurons exhibit diverse myelination patterns that scale between mouse brain regions and regenerate after demyelination
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    Twisting of the zebrafish heart tube during cardiac looping is a tbx5-dependent and tissue-intrinsic process
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    Adenosine A2A Receptors Contribute to the Radial Migration of Cortical Projection Neurons through the Regulation of Neuronal Polarization and Axon Formation
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    Transcriptional mechanism of IRF8 and PU.1 governs microglial activation in neurodegenerative condition
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    Disruption of NEUROD2 causes a neurodevelopmental syndrome with autistic features via cell-autonomous defects in forebrain glutamatergic neurons
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    The Role of 5-HT3 Receptors in Signaling from Taste Buds to Nerves
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    Interaction between Ras and Src clones causes interdependent tumor malignancy via Notch signaling in Drosophila
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    Mitochondrial cristae-remodeling protein OPA1 in POMC neurons couples Ca2+ homeostasis with adipose tissue lipolysis
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  143. Jul 2021
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    TSPAN5 Enriched Microdomains Provide a Platform for Dendritic Spine Maturation through Neuroligin-1 Clustering
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    Thalamic Input to Orbitofrontal Cortex Drives Brain-wide, Frequency-Dependent Inhibition Mediated by GABA and Zona Incerta
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    Panicle-Shaped Sympathetic Architecture in the Spleen Parenchyma Modulates Antibacterial Innate Immunity
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    Spatially resolved RNA-sequencing of the embryonic heart identifies a role for Wnt/β-catenin signaling in autonomic control of heart rate
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    A Distinct Role of the Autonomic Nervous System in Modulating the Function of Lymphatic Vessels under Physiological and Tumor-Draining Conditions
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    Serotonergic Modulation Enables Pathway-Specific Plasticity in a Developing Sensory Circuit in Drosophila
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    A microRNA negative feedback loop downregulates vesicle transport and inhibits fear memory
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    NANOS2 is a sequence-specific mRNA-binding protein that promotes transcript degradation in spermatogonial stem cells
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  156. Jun 2021
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    Kv1.1 channels regulate early postnatal neurogenesis in mouse hippocampus via the TrkB signaling pathway
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    Transcriptional repression by FEZF2 restricts alternative identities of cortical projection neurons
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    Sneezing reflex is mediated by a peptidergic pathway from nose to brainstem
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  162. onlinelibrary.wiley.com onlinelibrary.wiley.com
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  163. May 2021
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    Rapid degeneration of Drosophila olfactory neurons in Orco mutant maxillary palps
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    Derivation of Intermediate Pluripotent Stem Cells Amenable to Primordial Germ Cell Specification
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    Akt-mTOR hypoactivity in bipolar disorder gives rise to cognitive impairments associated with altered neuronal structure and function
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    Retinal and Callosal Activity-Dependent Chandelier Cell Elimination Shapes Binocularity in Primary Visual Cortex
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    Live-cell imaging reveals kinetic determinants of quality control triggered by ribosome stalling
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    Reticular Fibroblasts Expressing the Transcription Factor WT1 Define a Stromal Niche That Maintains and Replenishes Splenic Red Pulp Macrophages
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    The Scf/Kit pathway implements self-organized epithelial patterning
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    Homeostatic synaptic scaling establishes the specificity of an associative memory
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    Metabolic stress drives sympathetic neuropathy within the liver
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  174. Apr 2021
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    Enteroendocrine cells sense bacterial tryptophan catabolites to activate enteric and vagal neuronal pathways
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    Directed Evolution of a Selective and Sensitive Serotonin Sensor via Machine Learning
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    Single-Cell Transcriptomics Reveals Early Emergence of Liver Parenchymal and Non-parenchymal Cell Lineages
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    Cell Types Promoting Goosebumps Form a Niche to Regulate Hair Follicle Stem Cells
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    Cascade diversification directs generation of neuronal diversity in the hypothalamus
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    Spinal macrophages resolve nociceptive hypersensitivity after peripheral injury
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    Transcriptional profiling reveals potential involvement of microvillous TRPM5-expressing cells in viral infection of the olfactory epithelium
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  182. Mar 2021
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    Cytoneme delivery of Sonic Hedgehog from ligand-producing cells requires Myosin 10 and a Dispatched-BOC/CDON co-receptor complex
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    Simultaneous binding of Guidance Cues NET1 and RGM blocks extracellular NEO1 signaling
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    Biochemical evidence accumulates across neurons to drive a network-level eruption
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  186. Feb 2021
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    GluD2- and Cbln1-mediated competitive interactions shape the dendritic arbors of cerebellar Purkinje cells
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    RFamide-related peptide neurons modulate reproductive function and stress responses
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    Abstinence-dependent dissociable central amygdala microcircuits control drug craving
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    Puromycin reactivity does not accurately localize translation at the subcellular level
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    Activation of a neural stem cell transcriptional program in parenchymal astrocytes
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  192. www.frontiersin.org www.frontiersin.org
    Loss of the Major Phosphatidylserine or Phosphatidylethanolamine Flippases Differentially Affect Phagocytosis
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    A novel temporal identity window generates alternating Eve + /Nkx6 + motor neuron subtypes in a single progenitor lineage
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    Remyelination alters the pattern of myelin in the cerebral cortex
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    Pull-push neuromodulation of cortical plasticity enables rapid bi-directional shifts in ocular dominance
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    Sex-specific role for dopamine receptor D2 in dorsal raphe serotonergic neuron modulation of defensive acoustic startle and dominance behavior
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    ERα signaling in GHRH/Kiss1 dual phenotype neurons plays sex-specific roles in growth and puberty
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    isoTarget: A Genetic Method for Analyzing the Functional Diversity of Splicing Isoforms In Vivo
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    Synapse type-specific proteomic dissection identifies IgSF8 as a hippocampal CA3 microcircuit organizer
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    LRIG1-Mediated Inhibition of EGF Receptor Signaling Regulates Neural Precursor Cell Proliferation in the Neocortex
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    CNTF-STAT3-IL-6 Axis Mediates Neuroinflammatory Cascade across Schwann Cell-Neuron-Microglia
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    Single-cell analysis uncovers that metabolic reprogramming by ErbB2 signaling is essential for cardiomyocyte proliferation in the regenerating heart
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    A Neuro-hormonal Circuit for Paternal Behavior Controlled by a Hypothalamic Network Oscillation
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    Mapping of the excitatory, inhibitory, and modulatory afferent projections to the anatomically defined active expiratory oscillator in adult male rats
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    Catecholaminergic axons in the neocortex of adult mice regrow following brain injury
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    Shank2 Binds to aPKC and Controls Tight Junction Formation with Rap1 Signaling during Establishment of Epithelial Cell Polarity
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    Wireless Optogenetic Stimulation of Oxytocin Neurons in a Semi-natural Setup Dynamically Elevates Both Pro-social and Agonistic Behaviors
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    The Zonal Organization of Odorant Receptor Gene Choice in the Main Olfactory Epithelium of the Mouse
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    Differentiation Paths of Peyer’s Patch LysoDCs Are Linked to Sampling Site Positioning, Migration, and T Cell Priming
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    The Rap1 small GTPase is a critical mediator of the effects of stress on prefrontal cortical dysfunction
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    A Second Heart Field-Derived Vasculogenic Niche Contributes to Cardiac Lymphatics
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    DLK mediates the neuronal intrinsic immune response and regulates glial reaction and neuropathic pain
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    Prevention and Reversion of Pancreatic Tumorigenesis through a Differentiation-Based Mechanism
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    Fast Serotonin Voltammetry as a Versatile Tool for Mapping Dynamic Tissue Architecture: I. Responses at Carbon Fibers Describe Local Tissue Physiology
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    Stellate Cells, Hepatocytes, and Endothelial Cells Imprint the Kupffer Cell Identity on Monocytes Colonizing the Liver Macrophage Niche
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    Coronary Revascularization During Heart Regeneration Is Regulated by Epicardial and Endocardial Cues and Forms a Scaffold for Cardiomyocyte Repopulation
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    Thalamic Input to Orbitofrontal Cortex Drives Brain-wide, Frequency-Dependent Inhibition Mediated by GABA and Zona Incerta
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    TREK-1 and TRAAK Are Principal K+ Channels at the Nodes of Ranvier for Rapid Action Potential Conduction on Mammalian Myelinated Afferent Nerves
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    GDNF and GFRα1 Are Required for Proper Integration of Adult-Born Hippocampal Neurons
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    Panicle-Shaped Sympathetic Architecture in the Spleen Parenchyma Modulates Antibacterial Innate Immunity
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