155 Matching Annotations
  1. Last 7 days
  2. www.sciencedirect.com www.sciencedirect.com
    Mitoregulin self-associates to form likely homo-oligomeric pore-like complexes
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    1. scibot 21 Dec 2024
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    sciencedirect.com/science/article/pii/S2589004224027810
  3. Dec 2024
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    MYC Drives mRNA Pseudouridylation to Mitigate Proliferation-Induced Cellular Stress during Cancer Development
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    pmc.ncbi.nlm.nih.gov/articles/PMC11609627/
  5. Oct 2024
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    Alzheimer’s disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model
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    sciencedirect.com/science/article/pii/S0896627324006548
  7. Sep 2024
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    Atypical cellular responses mediated by intracellular constitutive active TrkB (NTRK2) kinase domains and a solely intracellular NTRK2-fusion oncogene
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    Input-specific localization of NMDA receptor GluN2 subunits in thalamocortical neurons
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  10. Aug 2024
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    Non-canonical function of ADAM10 in presynaptic plasticity
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    Caenorhabditis elegans SEL-5/AAK1 regulates cell migration and cell outgrowth independently of its kinase activity
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      DOI: 10.7554/eLife.91054

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  13. Jul 2024
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    A comprehensive Drosophila resource to identify key functional interactions between SARS-CoV-2 factors and host proteins
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    Arrestin-3-assisted activation of JNK3 mediates dopaminergic behavioral sensitization
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    Exosomal miRNA 16-5p/29a-3p from pancreatic cancer induce adipose atrophy by inhibiting adipogenesis and promoting lipolysis
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    cell.com/iscience/fulltext/S2589-0042(24)01571-2
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    Uncovering the BIN1-SH3 interactome underpinning centronuclear myopathy
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    Supernumerary proteins of the human mitochondrial ribosomal small subunit are integral for assembly and translation
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    Wnt/β-catenin signaling within multiple cell types dependent upon kramer regulates Drosophila intestinal stem cell proliferation
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    A phosphorylation-controlled switch confers cell cycle-dependent protein relocalization
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    ncbi.nlm.nih.gov/pmc/articles/PMC11185714/
  21. Jun 2024
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    Multimodal HLA-I genotype regulation by human cytomegalovirus US10 and resulting surface patterning
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  23. May 2024
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    Trio preserves motor synapses and prolongs motor ability during aging
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    cell.com/cell-reports/fulltext/S2211-1247(24)00584-9
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    Akap5 links synaptic dysfunction to neuroinflammatory signaling in a mouse model of infantile neuronal ceroid lipofuscinosis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11116793/
  26. Apr 2024
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Female-specific dysfunction of sensory neocortical circuits in a mouse model of autism mediated by mGluR5 and estrogen receptor α
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    ncbi.nlm.nih.gov/pmc/articles/PMC11112681/
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    Time-resolved profiling of RNA binding proteins throughout the mRNA life cycle
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    sciencedirect.com/science/article/pii/S1097276524002223
  29. Mar 2024
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    Transcriptional and metabolic effects of aspartate-glutamate carrier isoform 1 (AGC1) downregulation in mouse oligodendrocyte precursor cells (OPCs)
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      DOI: 10.1186/s11658-024-00563-z

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    Uncovering the BIN1-SH3 interactome underpinning centronuclear myopathy
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  32. Feb 2024
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    NEMF-mediated Listerin-independent mitochondrial translational surveillance by E3 ligase Pirh2 and mitochondrial protease ClpXP
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    sciencedirect.com/science/article/pii/S2211124724001888
  34. Jan 2024
  35. www.jneurosci.org www.jneurosci.org
    Loss of Depalmitoylation Disrupts Homeostatic Plasticity of AMPARs in a Mouse Model of Infantile Neuronal Ceroid Lipofuscinosis
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      DOI: 10.1523/JNEUROSCI.1113-23.2023

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  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lipopolysaccharide-induced sepsis impairs M2R-GIRK signaling in the mouse sinoatrial node
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      DOI: 10.1073/pnas.2210152120

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    Genetic insights into carbohydrate sulfotransferase 8 and its impact on the immunotherapy efficacy of cancer
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  38. Nov 2023
  39. www.sciencedirect.com www.sciencedirect.com
    Microglial Rac1 is essential for experience-dependent brain plasticity and cognitive performance
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    sciencedirect.com/science/article/pii/S2211124723014596
  40. Sep 2023
  41. www.sciencedirect.com www.sciencedirect.com
    Mechanism and evolutionary origins of alanine-tail C-degron recognition by E3 ligases Pirh2 and CRL2-KLHDC10
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  42. Aug 2023
  43. www.sciencedirect.com www.sciencedirect.com
    The SMC5/6 complex compacts and silences unintegrated HIV-1 DNA and is antagonized by Vpr
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    sciencedirect.com/science/article/pii/S1931312821001013
  44. www.sciencedirect.com www.sciencedirect.com
    Chaperone-mediated autophagy in neuronal dendrites utilizes activity-dependent lysosomal exocytosis for protein disposal
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    sciencedirect.com/science/article/pii/S2211124723010094
  45. Jul 2023
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A comprehensive Drosophila resource to identify key functional interactions between SARS-CoV-2 factors and host proteins
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  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Caffeine supplementation and FOXM1 inhibition enhance the antitumor effect of statins in neuroblastoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10320471/
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    Protocol to identify human subcellular alternative protein interactions using cross-linking mass spectrometry
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    sciencedirect.com/science/article/pii/S2666166723003477
  49. Jun 2023
  50. www.sciencedirect.com www.sciencedirect.com
    ROTACs leverage signaling-incompetent R-spondin for targeted protein degradation
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      DOI: 10.1016/j.chembiol.2023.05.010

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    sciencedirect.com/science/article/pii/S2451945623001538
  51. dx.doi.org dx.doi.org
    Novel MKRN3 Missense Mutations Associated with Central Precocious Puberty Reveal Distinct Effects on Ubiquitination
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      DOI: 10.1210/clinem/dgad151

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  52. 52.53.155.43 52.53.155.43
    can-22-3450-html.html
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  53. May 2023
  54. www.nature.com www.nature.com
    Venlafaxine antagonizes the noradrenaline-promoted colon cancer progression by inhibiting the norepinephrine transporter
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      DOI: 10.1038/s41420-023-01447-5

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    nature.com/articles/s41420-023-01447-5
  55. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Snail acetylation by autophagy-derived acetyl-coenzyme A promotes invasion and metastasis of KRAS-LKB1 co-mutated lung cancer cells
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      DOI: 10.1002/cac2.12332

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  56. Apr 2023
  57. www.nature.com www.nature.com
    Targeting USP2 regulation of VPRBP-mediated degradation of p53 and PD-L1 for cancer therapy
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    SLFN5-mediated chromatin dynamics sculpt higher-order DNA repair topology
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    Affinity-ranking BIN1 interactions and screening natural BIN1 variants that may cause neuromuscular disorders
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  60. Mar 2023
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    FSBP suppresses tumor cell migration by inhibiting the JNK pathway
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    Glycine receptor autoantibody binding to the extracellular domain is independent from receptor glycosylation
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  63. Feb 2023
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    Clonal hematopoiesis driven by chromosome 1q/MDM4 trisomy defines a canonical route toward leukemia in Fanconi anemia
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  65. Jan 2023
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    Employing non-targeted interactomics approach and subcellular fractionation to increase our understanding of the ghost proteome
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    Primary cilia are WNT-transducing organelles whose biogenesis is controlled by a WNT-PP1 axis
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    Multimodal HLA-I genotype regulation by human cytomegalovirus US10 and resulting surface patterning
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    A single RET mutation in Hirschsprung disease induces intestinal aganglionosis via a dominant-negative mechanism
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    Jacob-induced transcriptional inactivation of CREB promotes Aβ-induced synapse loss in Alzheimer's disease
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  72. Dec 2022
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    CKII Control of Axonal Plasticity Is Mediated by Mitochondrial Ca2+ via Mitochondrial NCLX
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    Separating the contributions of SLC26A9 and CFTR to anion secretion in primary human bronchial epithelia
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  75. Nov 2022
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    POLθ processes ssDNA gaps and promotes replication fork progression in BRCA1-deficient cells
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  77. Sep 2022
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    ABCC1 transporter exports the immunostimulatory cyclic dinucleotide cGAMP
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  79. Aug 2022
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    Regulation of membrane fluidity by RNF145-triggered degradation of the lipid hydrolase ADIPOR2
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    Endocytic membrane repair by ESCRT-III controls antigen export to the cytosol during antigen cross-presentation
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    NMDA receptor-targeted enrichment of CaMKIIα improves fear memory
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  83. Jul 2022
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    Slitrk2 deficiency causes hyperactivity with altered vestibular function and serotonergic dysregulation
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  86. May 2022
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    Increased microtubule growth triggered by microvesicle-mediated paracrine signaling is required for melanoma cancer cell invasion
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    A family of conserved bacterial virulence factors dampens interferon responses by blocking calcium signaling
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    EMT, Stemness, and Drug Resistance in Biological Context: A 3D Tumor Tissue/In Silico Platform for Analysis of Combinatorial Treatment in NSCLC with Aggressive KRAS-Biomarker Signatures
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  90. Mar 2022
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    Viperin triggers ribosome collision-dependent translation inhibition to restrict viral replication
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    Mutant CHCHD10 causes an extensive metabolic rewiring that precedes OXPHOS dysfunction in a murine model of mitochondrial cardiomyopathy
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    An HNF1α truncation associated with maturity-onset diabetes of the young impairs pancreatic progenitor differentiation by antagonizing HNF1β function
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  94. Jan 2022
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    Histone Acetylation Defects in Brain Precursor Cells: A Potential Pathogenic Mechanism Causing Proliferation and Differentiation Dysfunctions in Mitochondrial Aspartate-Glutamate Carrier Isoform 1 Deficiency
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    Genotype-specific features reduce the susceptibility of South American yellow fever virus strains to vaccine-induced antibodies
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  98. Dec 2021
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    Ocimum basilicum but not Ocimum gratissimum present cytotoxic effects on human breast cancer cell line MCF-7, inducing apoptosis and triggering mTOR/Akt/p70S6K pathway
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  100. Nov 2021
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    Molecular and functional architecture of striatal dopamine release sites
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    Non-genomic rewiring of vitamin D receptor to p53 as a key to Alzheimer's disease
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  103. Oct 2021
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    Munc13-1 is a Ca2+-phospholipid-dependent vesicle priming hub that shapes synaptic short-term plasticity and enables sustained neurotransmission
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    Multiomics of synaptic junctions reveals altered lipid metabolism and signaling following environmental enrichment
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  106. Sep 2021
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    Proteopathic tau primes and activates interleukin-1β via myeloid-cell-specific MyD88- and NLRP3-ASC-inflammasome pathway
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  108. Aug 2021
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    Regulation of T‐type Ca2+ channel expression by interleukin‐6 in sensory‐like ND7/23 cells post‐herpes simplex virus (HSV‐1) infection
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  113. Jul 2021
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    The Anti-amyloid Compound DO1 Decreases Plaque Pathology and Neuroinflammation-Related Expression Changes in 5xFAD Transgenic Mice
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    Isoflurane mediated neuropathological and cognitive impairments in the triple transgenic Alzheimer’s mouse model are associated with hippocampal synaptic deficits in an age-dependent manner
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    Cargo Release from Myosin V Requires the Convergence of Parallel Pathways that Phosphorylate and Ubiquitylate the Cargo Adaptor
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    Argonaute-CLIP delineates versatile, functional RNAi networks in Aedes aegypti, a major vector of human viruses
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    The SMC5/6 complex compacts and silences unintegrated HIV-1 DNA and is antagonized by Vpr
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  134. Feb 2021
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    Integrated pharmaco-proteogenomics defines two subgroups in isocitrate dehydrogenase wild-type glioblastoma with prognostic and therapeutic opportunities
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  138. Jan 2021
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    c–Jun N–terminal Kinase Mediates Ligand-independent p75NTR Signaling in Mesencephalic Cells Subjected to Oxidative Stress
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  140. Oct 2020
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  142. Sep 2020
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    Lysophosphatidic Acid-Mediated GPR35 Signaling in CX3CR1+ Macrophages Regulates Intestinal Homeostasis
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    Complexin Suppresses Spontaneous Exocytosis by Capturing the Membrane-Proximal Regions of VAMP2 and SNAP25
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    Structural modeling, mutation analysis, and in vitro expression of usherin, a major protein in inherited retinal degeneration and hearing loss
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    Defective Mitochondrial Cardiolipin Remodeling Dampens HIF-1α Expression in Hypoxia
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    Lyssavirus Vaccine with a Chimeric Glycoprotein Protects across Phylogroups
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    Auxiliary α2δ1 and α2δ3 Subunits of Calcium Channels Drive Excitatory and Inhibitory Neuronal Network Development
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      peroxidase-conjugated AffiniPure goat anti-mouse IgG

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    KLF6 and STAT3 co-occupy regulatory DNA and functionally synergize to promote axon growth in CNS neurons
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      HRP-conjugated secondary antibody

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    Testisin/Prss21 deficiency causes increased vascular permeability and a hemorrhagic phenotype during luteal angiogenesis
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      goat anti-mouse-HRP

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  154. Jan 2020
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    Loss of Function of Phosphodiesterase 11A4 Shows that Recent and Remote Long-Term Memories Can Be Uncoupled
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    DUX4-Induced Histone Variants H3.X and H3.Y Mark DUX4 Target Genes for Expression
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    The Spatiotemporal Pattern and Intensity of p53 Activation Dictates Phenotypic Diversity in p53-Driven Developmental Syndromes
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  158. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    Endogenous IGF Signaling Directs Heterogeneous Mesoderm Differentiation in Human Embryonic Stem Cells
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      DOI: 10.1016/j.celrep.2019.11.047

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    DUX4 Suppresses MHC Class I to Promote Cancer Immune Evasion and Resistance to Checkpoint Blockade
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      DOI: 10.1016/j.devcel.2019.06.011

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    Fibroblast Growth Factor 21 Drives Dynamics of Local and Systemic Stress Responses in Mitochondrial Myopathy with mtDNA Deletions
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      DOI: 10.1016/j.cmet.2019.08.019

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    Mice conditionally expressing RET(C618F) mutation display C cell hyperplasia and hyperganglionosis of the enteric nervous system
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      DOI: 10.1002/dvg.23292

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    Transient Confinement of CaV2.1 Ca2+-Channel Splice Variants Shapes Synaptic Short-Term Plasticity
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      DOI: 10.1016/j.neuron.2019.04.030

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    Adaptation to Host-Specific Bacterial Pathogens Drives Rapid Evolution of a Human Innate Immune Receptor
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      DOI: 10.1016/j.cub.2019.01.058

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    NLRP12 Regulates Anti-viral RIG-I Activation via Interaction with TRIM25
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      DOI: 10.1016/j.chom.2019.02.013

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    Allosteric Regulation of NCLX by Mitochondrial Membrane Potential Links the Metabolic State and Ca2+ Signaling in Mitochondria
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      DOI: 10.1016/j.celrep.2018.11.084

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    Tracing MYC Expression for Small Molecule Discovery
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  169. Nov 2018
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    A Short Tandem Repeat-Enriched RNA Assembles a Nuclear Compartment to Control Alternative Splicing and Promote Cell Survival
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  172. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitoregulin: A lncRNA-Encoded Microprotein that Supports Mitochondrial Supercomplexes and Respiratory Efficiency
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  173. www.sciencedirect.com www.sciencedirect.com
    The Inhibitory Innate Immune Sensor NLRP12 Maintains a Threshold against Obesity by Regulating Gut Microbiota Homeostasis
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    Poly(ADP-Ribose) Prevents Pathological Phase Separation of TDP-43 by Promoting Liquid Demixing and Stress Granule Localization
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    Pan-Cancer Metabolic Signature Predicts Co-Dependency on Glutaminase and De Novo Glutathione Synthesis Linked to a High-Mesenchymal Cell State
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    Tau Does Not Stabilize Axonal Microtubules but Rather Enables Them to Have Long Labile Domains
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    Mitoregulin: A lncRNA-Encoded Microprotein that Supports Mitochondrial Supercomplexes and Respiratory Efficiency
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  180. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Interaction of CacyBP/SIP with NPM1 and its influence on NPM1 localization and function in oxidative stress
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    onlinelibrary.wiley.com/doi/full/10.1002/jcp.26797
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    Clotrimazole is effective for the regression of endometriotic implants in a Wistar rat experimental model of endometriosis
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    sciencedirect.com/science/article/pii/S0303720718301242
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    onlinelibrary.wiley.com/doi/10.1111/jnc.14310
  183. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NuRD and CAF-1-mediated silencing of the D4Z4 array is modulated by DUX4-induced MBD3L proteins
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    Radial Glial Fibers Promote Neuronal Migration and Functional Recovery after Neonatal Brain Injury
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    sciencedirect.com/science/article/pii/S1934590917304575
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    Polo-like Kinase Couples Cytoplasmic Protein Gradients in the C. elegans Zygote
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  186. academic.oup.com academic.oup.com
    The Response of Prostate Smooth Muscle Cells to Testosterone Is Determined by the Subcellular Distribution of the Androgen Receptor
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    academic.oup.com/endo/article/159/2/945/4675087
  187. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Rapid DNA replication origin licensing protects stem cell pluripotency
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    ncbi.nlm.nih.gov/pmc/articles/PMC5720591/
  188. Nov 2017
  189. www.sciencedirect.com www.sciencedirect.com
    Angiopoietin-like 4 Is a Wnt Signaling Antagonist that Promotes LRP6 Turnover
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    Stable and Potent Selenomab-Drug Conjugates
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    The Histone Acetyltransferase Mst2 Protects Active Chromatin from Epigenetic Silencing by Acetylating the Ubiquitin Ligase Brl1
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    Preprotein Conformational Dynamics Drive Bivalent Translocase Docking and Secretion
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    Eradication of Tumors through Simultaneous Ablation of CD276/B7-H3-Positive Tumor Cells and Tumor Vasculature
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    Evidence that increased Kcnj6 gene dose is necessary for deficits in behavior and dentate gyrus synaptic plasticity in the Ts65Dn mouse model of Down syndrome
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    sciencedirect.com/science/article/pii/S0969996117300578
  195. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Phosphofructokinase‐P Modulates P44/42 MAPK Levels in HeLa Cells
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    onlinelibrary.wiley.com/doi/10.1002/jcb.25774/full
  196. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Monoacylglycerol Lipase Inhibitor JZL184 Improves Behavior and Neural Properties in Ts65Dn Mice, a Model of Down Syndrome
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    ncbi.nlm.nih.gov/pmc/articles/PMC4256450/
  197. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Isoform‐specific localization of Nogo protein in the optic pathway of mouse embryos
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      (Jackson ImmunoResearch Labs Cat# 115-035-146, RRID:AB_2307392)

      SciCrunch record: RRID:AB_2307392

      Alternate resolvers: SciCrunch xml N2T identifiers.org

      What is this?

      RRID:AB_2307392 RRIDCUR:Validated
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    onlinelibrary.wiley.com/doi/10.1002/cne.23953/full