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  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The X-linked intellectual disability gene CUL4B is critical for memory and synaptic function
    6
    1. scibot 22 Dec 2024
      RRID:AB_2313567

      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

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    2. scibot 20 Dec 2024
      RRID:AB_2313567

      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

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    3. scibot 19 Dec 2024
      RRID:AB_2313567

      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

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    4. scibot 18 Dec 2024
      RRID:AB_2313567

      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

      RRID:AB_2313567
    5. scibot 17 Dec 2024
      RRID:AB_2313567

      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

      RRID:AB_2313567
    6. scibot 16 Dec 2024
      RRID:AB_2313567

      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

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  3. www.nature.com www.nature.com
    Lithocholic acid binds TULP3 to activate sirtuins and AMPK to slow down ageing
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    1. scibot 21 Dec 2024
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      DOI: 10.1038/s41586-024-08348-2

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    nature.com/articles/s41586-024-08348-2
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    Lithocholic acid phenocopies anti-ageing effects of calorie restriction
    1
    1. scibot 21 Dec 2024
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      DOI: 10.1038/s41586-024-08329-5

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    nature.com/articles/s41586-024-08329-5
  5. aacrjournals.org aacrjournals.org
    Clotting Promotes Glioma Growth and Infiltration Through Activation of Focal Adhesion Kinase
    1
    1. scibot 19 Dec 2024
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      DOI: 10.1158/2767-9764.CRC-24-0164

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    aacrjournals.org/cancerrescommun/article/4/12/3124/750544/Clotting-Promotes-Glioma-Growth-and-Infiltration
  6. Dec 2024
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The X-linked intellectual disability gene CUL4B is critical for memory and synaptic function
    5
    1. scibot 15 Dec 2024
      RRID:AB_2313567

      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

      RRID:AB_2313567
    2. scibot 14 Dec 2024
      RRID:AB_2313567

      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

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    3. scibot 13 Dec 2024
      RRID:AB_2313567

      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

      RRID:AB_2313567
    4. scibot 12 Dec 2024
      RRID:AB_2313567

      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

      RRID:AB_2313567
    5. scibot 11 Dec 2024
      RRID:AB_2313567

      Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers

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    pmc.ncbi.nlm.nih.gov/articles/PMC11619648/
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Eicosapentaenoic acid induces macrophage Mox polarization to prevent diabetic cardiomyopathy
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    1. scibot 11 Dec 2024
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      DOI: 10.1038/s44319-024-00271-x

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  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The WAVE regulatory complex interacts with Boc and is required for Shh-mediated axon guidance
    1
    1. scibot 11 Dec 2024
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      DOI: 10.1016/j.isci.2024.111333

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    TTF2 promotes replisome eviction from stalled forks in mitosis
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    1. scibot 05 Dec 2024
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      DOI: 10.1101/2024.11.30.626186

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    biorxiv.org/content/10.1101/2024.11.30.626186v1
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    Biased signaling by mutant EGFR underlies dependence on PKCα in lung adenocarcinoma
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      DOI: 10.1016/j.celrep.2024.115026

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    sciencedirect.com/science/article/pii/S2211124724013779
  12. Nov 2024
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    Ethanol modulates astrocyte activation and neuroinflammation via miR-339/NLRP6 inflammasome signaling
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      DOI: 10.1016/j.freeradbiomed.2024.11.014

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    Autophagy-dependent splicing control directs translation toward inflammation during senescence
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      DOI: 10.1016/j.devcel.2024.10.008

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    Degradome analysis to identify direct protein substrates of small-molecule degraders
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    PI3K/Akt inhibition promotes AR activity and prostate cancer cell proliferation through p35-CDK5 modulation
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      DOI: 10.1016/j.bbadis.2024.167568

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  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mechano-regulation of GLP-1 production by Piezo1 in intestinal L cells
    1
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      DOI: 10.7554/eLife.97854

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  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Laminin-α2 chain deficiency in skeletal muscle causes dysregulation of multiple cellular mechanisms
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      DOI: 10.26508/lsa.202402829

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    ncbi.nlm.nih.gov/pmc/articles/PMC11463332/
  19. Oct 2024
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pharmacologic inhibition of eIF4A blocks NRF2 synthesis to prevent osteosarcoma metastasis
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      DOI: 10.1158/1078-0432.CCR-24-1317

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    ncbi.nlm.nih.gov/pmc/articles/PMC11443218/
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    Mitotic ER-mitochondria contact enhances mitochondrial Ca2+ influx to promote cell division
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    The TMEM132B-GABAA receptor complex controls alcohol actions in the brain
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      DOI: 10.1016/j.cell.2024.09.006

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      DOI: 10.1016/j.cell.2024.09.006

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    sciencedirect.com/science/article/pii/S0092867424010249
  23. Sep 2024
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IKKɛ induces STING non-IFN immune responses via a mechanism analogous to TBK1
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      DOI: 10.1016/j.isci.2024.110693

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  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Anabolic deficits and divergent unfolded protein response underlie skeletal and cardiac muscle growth impairments in the Yoshida hepatoma tumor model of cancer cachexia
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      DOI: 10.14814/phy2.70044

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    gp78-regulated KAP1 phosphorylation induces radioresistance in breast cancer by facilitating PPP1CC/PPP2CA ubiquitination
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      DOI: 10.1016/j.isci.2024.110847

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    sciencedirect.com/science/article/pii/S2589004224020728
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    Redox-dependent condensation and cytoplasmic granulation by human ssDNA-binding protein-1 delineate roles in oxidative stress response
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      DOI: 10.1016/j.isci.2024.110788

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    sciencedirect.com/science/article/pii/S2589004224020133
  28. www.sciencedirect.com www.sciencedirect.com
    Overcoming Adaptive Resistance to KRAS and MEK Inhibitors by Co-targeting mTORC1/2 Complexes in Pancreatic Cancer
    1
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      DOI: 10.1016/j.xcrm.2020.100131

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    sciencedirect.com/science/article/pii/S2666379120301737
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Nuclear actin is a critical regulator of Drosophila female germline stem cell maintenance
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      DOI: 10.1101/2024.08.27.609996

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    ncbi.nlm.nih.gov/pmc/articles/PMC11383290/
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MED12 and CDK8/19 modulate androgen receptor activity and enzalutamide response in prostate cancer
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      DOI: 10.1210/endocr/bqae114

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    E3 ubiquitin ligase ANKIB1 attenuates antiviral immune responses by promoting K48-linked polyubiquitination of MAVS
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      DOI: 10.1016/j.celrep.2024.114687

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    sciencedirect.com/science/article/pii/S2211124724010386
  32. Aug 2024
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CD3-engaging bispecific antibodies trigger a paracrine regulated wave of T-cell recruitment for effective tumor killing
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      DOI: 10.1038/s42003-024-06682-9

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    ncbi.nlm.nih.gov/pmc/articles/PMC11322607/
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neuropeptide Y receptor activation preserves inner retinal integrity through PI3K/Akt signaling in a glaucoma mouse model
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      DOI: 10.1093/pnasnexus/pgae299

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    ncbi.nlm.nih.gov/pmc/articles/PMC11305140/
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    Protocol for analyzing TRAIL- and Fas-induced signaling complexes by immunoprecipitation from human cells
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      DOI: 10.1016/j.xpro.2024.103126

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    sciencedirect.com/science/article/pii/S2666166724002910
  36. www.sciencedirect.com www.sciencedirect.com
    Oxidative stress reprograms the transcriptional coactivator Yki to suppress cell proliferation
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      DOI: 10.1016/j.celrep.2024.114584

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  37. academic.oup.com academic.oup.com
    Glycerol Phenylbutyrate treatment of two patients with Monocarboxylate Transporter 8 deficiency
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      RRID:AB_231356

      DOI: 10.1210/clinem/dgae146

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    academic.oup.com/jcem/advance-article-abstract/doi/10.1210/clinem/dgae146/7625621
  38. academic.oup.com academic.oup.com
    First Compound Heterozygous Mutations of DMP1 Causing Rare Autosomal Recessive Hypophosphatemic Rickets Type 1
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      DOI: 10.1210/clinem/dgac640

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    academic.oup.com/jcem/advance-article-abstract/doi/10.1210/clinem/dgac640/6806102
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    Therapy-induced DNA methylation inactivates MCT1 and renders tumor cells vulnerable to MCT4 inhibition
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      DOI: 10.1016/j.celrep.2021.109202

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    Dynamic changes in complexes of IRE1α, PERK, and ATF6α during endoplasmic reticulum stress | Molecular Biology of the Cell
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    Nogo‐B is the major form of Nogo at the floor plate and likely mediates crossing of commissural axons in the mouse spinal cord
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    Differential contributions of microglial and neuronal IKKβ to synaptic plasticity and associative learning in alert behaving mice
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    A Comprehensive Protocol for Efficient Differentiation of Human NPCs into Electrically Competent Neurons
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    The Effects of Cathepsin B Inhibition in the Face of Diffuse Traumatic Brain Injury and Secondary Intracranial Pressure Elevation
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    Mammalian SWI/SNF complex activity regulates POU2F3 and constitutes a targetable dependency in small cell lung cancer
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    Alterations of ceramide synthesis induce PD-L1 internalization and signaling to regulate tumor metastasis and immunotherapy response
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    Obese mice have decreased uterine contractility and altered energy metabolism in the uterus at term gestation
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    Artemisinins ameliorate polycystic ovarian syndrome by mediating LONP1-CYP11A1 interaction
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    Proteomic analysis reveals a PLK1-dependent G2/M degradation program and a role for AKAP2 in coordinating the mitotic cytoskeleton
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    Desmosomal Cadherin Tension Loss in Pemphigus Vulgaris Mediated by the Inhibition of Active RhoA at Cell-Cell Adhesions
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  58. May 2024
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    Analyzing efficiency of a lentiviral shRNA knockdown system in human enteroids using western blot and flow cytometry
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    An unconventional VH1-2 antibody tolerates escape mutations and shows an antigenic hotspot on SARS-CoV-2 spike
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    A RIPK1-specific PROTAC degrader achieves potent antitumor activity by enhancing immunogenic cell death
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    Upregulation of neuronal ER-phagy improves organismal fitness and alleviates APP toxicity
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    Unprocessed Genomic Uracil as a Source of DNA Replication Stress in Cancer Cells
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    Hypomethylation-enhanced CRTC2 expression drives malignant phenotypes and primary resistance to immunotherapy in hepatocellular carcinoma
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  70. Apr 2024
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    Lysosomal dysfunction by inactivation of V-ATPase drives innate immune response in C. elegans
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    O-GlcNAcylation of RBM14 contributes to elevated cellular O-GlcNAc through regulation of OGA protein stability
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    Semaphorin3C identified as mediator of neuroinflammation and microglia polarization after spinal cord injury
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    Co-inhibition of BET and NAE enhances BIM-dependent apoptosis with augmented cancer therapeutic efficacy
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  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    Endocytic activation and exosomal secretion of matriptase stimulate the second wave of EGF signaling to promote skin and breast cancer invasion
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    ATF4-SLC7A11-GSH axis mediates the acquisition of immunosuppressive properties by activated CD4+ T cells in low arginine condition
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    PRRC2B modulates oligodendrocyte progenitor cell development and myelination by stabilizing Sox2 mRNA
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    A unique chaperoning mechanism in class A JDPs recognizes and stabilizes mutant p53
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    Pneumococcal sialidase promotes bacterial survival by fine-tuning of pneumolysin-mediated membrane disruption
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    Securin acetylation prevents precocious separase activation and premature sister chromatid separation
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    Rim aperture of yeast autophagic membranes balances cargo inclusion with vesicle maturation
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    Uncovering the BIN1-SH3 interactome underpinning centronuclear myopathy
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    HERC5-catalyzed ISGylation potentiates cGAS-mediated innate immunity
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    The differential regulation of placenta trophoblast bisphosphoglycerate mutase in fetal growth restriction: preclinical study in mice and observational histological study of human placenta
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    Glycolytic enzyme PFKFB3 regulates sphingosinae 1-phosphate receptor 1 in proangiogenic glomerular endothelial cells under diabetic condition
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    Dual roles of CCDC102A in governing centrosome duplication and cohesion
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    PNMA2 forms immunogenic non-enveloped virus-like capsids associated with paraneoplastic neurological syndrome
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  93. Jan 2024
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    Unique vulnerability of RAC1-mutant melanoma to combined inhibition of CDK9 and immune checkpoints
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    In silico protein interaction screening uncovers DONSON’s role in replication initiation
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    Vinorelbine causes a neuropathic pain-like state in mice via STING and MNK1 signaling associated with type I interferon induction.
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    Protocol to analyze the role of various metabolites in impacting global RNA 5-methylcytosine levels in cultured cells by dot blot
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    Transgelin Promotes Glioblastoma Stem Cell Hypoxic Responses and Maintenance Through p53 Acetylation
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    Decoupling NAD+ metabolic dependency in chondrosarcoma by targeting the SIRT1-HIF-2α axis
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    Pib2 is a cysteine sensor involved in TORC1 activation in Saccharomyces cerevisiae
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    Adhesion-induced cortical flows pattern E-cadherin-mediated cell contacts
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    Sequestration of translation initiation factors in p62 condensates
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    Smad4 sequestered in SFPQ condensates prevents TGF-β tumor-suppressive signaling
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    Proteomics analysis of the brain from a Gaucher disease mouse identifies pathological pathways including a possible role for transglutaminase 1
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    Identification of ZIP8-induced ferroptosis as a major type of cell death in monocytes under sepsis conditions
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    SYK ubiquitination by CBL E3 ligases restrains cross-presentation of dead cell-associated antigens by type 1 dendritic cells
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    Engineering CD276/B7-H3-targeted antibody-drug conjugates with enhanced cancer-eradicating capability
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    Nutrient-regulated control of lysosome function by signaling lipid conversion
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    NAAG synthetase deficiency has only low influence on pathogenesis in a Canavan disease mouse model
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    MiR-337-3p improves metabolic-associated fatty liver disease through regulation of glycolipid metabolism
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    p120 RasGAP and ZO-2 are essential for Hippo signaling and tumor-suppressor function mediated by p190A RhoGAP
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    Unbiased interrogation of functional lysine residues in human proteome
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    Histone methylation mediated by NSD1 is required for the establishment and maintenance of neuronal identities
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    Biophysical properties of NaV1.5 channels from atrial-like and ventricular-like cardiomyocytes derived from human induced pluripotent stem cells
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    Analysis of CDPK1 targets identifies a trafficking adaptor complex that regulates microneme exocytosis in Toxoplasma
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  121. Oct 2023
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    PRMT5 mediates FoxO1 methylation and subcellular localization to regulate lipophagy in myogenic progenitors
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    CPT1C is required for synaptic plasticity and oscillatory activity that supports motor, associative, and non-associative learning
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    The histone chaperone ANP32B regulates chromatin incorporation of the atypical human histone variant macroH2A
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    Identification of hyperoxidized PRDX3 as a ferroptosis marker reveals ferroptotic damage in chronic liver diseases
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    Antibody-directed extracellular proximity biotinylation reveals that Contactin-1 regulates axo-axonic innervation of axon initial segments
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    A Drosophila model of diabetic neuropathy reveals a role of proteasome activity in the glia
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  166. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Alpha 7-nicotinic cholinergic regulation of pericyte-containing retinal capillaries
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  167. May 2023
  168. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inflammatory and alternatively activated macrophages independently induce metaplasia but cooperatively drive pancreatic precancerous lesion growth
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  169. www.sciencedirect.com www.sciencedirect.com
    Heat shock factor 1 (HSF1) specifically potentiates c-MYC-mediated transcription independently of the canonical heat shock response
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    Depletion of CUL4B in macrophages ameliorates diabetic kidney disease via miR-194-5p/ITGA9 axis
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    Ubiquitin-independent proteasomal degradation driven by C-degron pathways
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    The mitochondrial intermembrane space protein mitofissin drives mitochondrial fission required for mitophagy
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  173. www.biorxiv.org www.biorxiv.org
    Kappa Opioid Receptor Antagonism Rescues Genetic Perturbation of Dopamine Homeostasis: Molecular, Physiological and Behavioral Consequences
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  174. www.science.org www.science.org
    Phosphorylation of neuroligin-2 by PKA regulates its cell surface abundance and synaptic stabilization
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  175. Apr 2023
  176. www.sciencedirect.com www.sciencedirect.com
    Thymidine kinase 1 drives hepatocellular carcinoma in enzyme-dependent and -independent manners
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  177. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Antibody-directed extracellular proximity biotinylation reveals Contactin-1 regulates axo-axonic innervation of axon initial segments
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  178. www.biorxiv.org www.biorxiv.org
    Affinity-ranking BIN1 interactions and screening natural BIN1 variants that may cause neuromuscular disorders
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  179. Mar 2023
  180. www.sciencedirect.com www.sciencedirect.com
    STING activation in platelets aggravates septic thrombosis by enhancing platelet activation and granule secretion
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    Proximity labeling reveals OTUD3 as a DNA-binding deubiquitinase of cGAS
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  182. www.sciencedirect.com www.sciencedirect.com
    Topological regulation of a transmembrane protein by luminal-to-cytosolic retrotranslocation of glycosylated sequence
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  183. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Non-muscle myosin II drives critical steps of nematocyst morphogenesis
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  184. www.embopress.org www.embopress.org
    Two Hippo signaling modules orchestrate liver size and tumorigenesis
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  185. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  186. www.sciencedirect.com www.sciencedirect.com
    A spinal muscular atrophy modifier implicates the SMN protein in SNARE complex assembly at neuromuscular synapses
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  187. Feb 2023
  188. www.sciencedirect.com www.sciencedirect.com
    Exercise-activated hepatic autophagy via the FN1-α5β1 integrin pathway drives metabolic benefits of exercise
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    TRIM21-dependent target protein ubiquitination mediates cell-free Trim-Away
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  190. elifesciences.org elifesciences.org
    A concerted mechanism involving ACAT and SREBPs by which oxysterols deplete accessible cholesterol to restrict microbial infection
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  191. www.sciencedirect.com www.sciencedirect.com
    Mechanism of signal-anchor triage during early steps of membrane protein insertion
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  192. www.sciencedirect.com www.sciencedirect.com
    Clonal hematopoiesis driven by chromosome 1q/MDM4 trisomy defines a canonical route toward leukemia in Fanconi anemia
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  193. Jan 2023
  194. www.sciencedirect.com www.sciencedirect.com
    N-glycosylated intestinal protein BCF-1 shapes microbial colonization by binding bacteria via its fimbrial protein
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    Gasdermin D pore-forming activity is redox-sensitive
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    Immunohistochemical localisation of vasopressin/oxytocin-type, corazonin-type and luqin-type neuropeptide expression in the starfish Asterias rubens using antibodies to the C-terminal region of precursor proteins
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  197. aacrjournals.org aacrjournals.org
    Loss of VOPP1 Contributes to BET Inhibitor Acquired Resistance in Non–Small Cell Lung Cancer Cells
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  198. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Brain-derived neurotrophic factor (BDNF) induces antagonistic action to Nogo signaling by the upregulation of lateral olfactory tract usher substance (LOTUS) expression
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  199. www.sciencedirect.com www.sciencedirect.com
    RNA methylation influences TDP43 binding and disease pathogenesis in models of amyotrophic lateral sclerosis and frontotemporal dementia
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  200. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Native holdup (nHU) to measure binding affinities from cell extracts
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  201. Dec 2022
  202. link.springer.com link.springer.com
    LOTUS suppresses amyloid β-induced dendritic spine elimination through the blockade of amyloid β binding to PirB
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  203. www.sciencedirect.com www.sciencedirect.com
    Tim-4 reprograms cholesterol metabolism to suppress antiviral innate immunity by disturbing the Insig1-SCAP interaction in macrophages
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  204. Nov 2022
  205. www.sciencedirect.com www.sciencedirect.com
    Calreticulin mutations affect its chaperone function and perturb the glycoproteome
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  206. www.mdpi.com www.mdpi.com
    Neuroprotective Effects of Neuropeptide Y on Human Neuroblastoma SH-SY5Y Cells in Glutamate Excitotoxicity and ER Stress Conditions
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