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57 Matching Annotations

Dec 2025
www.sciencedirect.com:5037 www.sciencedirect.com:5037

Oxidized MIF is an Alzheimer’s disease drug target relaying external risk factors to tau pathology

1
1. scibot 23 Dec 2025
  
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  RRID:AB_2314654
  
  DOI: 10.1016/j.xcrm.2025.102520
  
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sciencedirect.com:5037/science/article/pii/S2666379125005932
Sep 2025
www.sciencedirect.com www.sciencedirect.com

Protocol for 3D direct reprogramming of human glia into dopaminergic neurons with gene expression and immunocytochemistry validation

1
1. scibot 16 Sep 2025
  
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  RRID:AB_2314654
  
  DOI: 10.1016/j.xpro.2025.104088
  
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sciencedirect.com/science/article/pii/S2666166725004940
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A rare genetic variant confers resistance to neurodegeneration across multiple neurological disorders by augmenting selective autophagy

1
1. scibot 13 Sep 2025
  
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  RRID:AB_2314654
  
  DOI: 10.1016/j.neuron.2025.08.018
  
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sciencedirect.com/science/article/pii/S0896627325006245
Jun 2025
www.liebertpub.com www.liebertpub.com

Sexually Dimorphic Responses Reveal Multifaceted Benefits of Glibenclamide in Traumatic Brain Injury

4
1. scibot 26 Jun 2025
  
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  RRID:AB_2314654
  
  DOI: 10.1089/neu.2024.0232
  
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2. scibot 25 Jun 2025
  
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  RRID:AB_2314654
  
  DOI: 10.1089/neu.2024.0232
  
  Resource: (Thermo Fisher Scientific Cat# MN1000, RRID:AB_2314654)
  
  Curator: @sjvitug
  
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3. scibot 24 Jun 2025
  
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  RRID:AB_2314654
  
  DOI: 10.1089/neu.2024.0232
  
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4. scibot 24 Jun 2025
  
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  RRID:AB_2314654
  
  DOI: 10.1089/neu.2024.0232
  
  Resource: (Thermo Fisher Scientific Cat# MN1000, RRID:AB_2314654)
  
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liebertpub.com/doi/10.1089/neu.2024.0232
www.sciencedirect.com www.sciencedirect.com

The R136S mutation in the APOE3 gene confers resilience against tau pathology via inhibition of the cGAS-STING-IFN pathway

1
1. scibot 24 Jun 2025
  
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  RRID:AB_2314654
  
  DOI: 10.1016/j.immuni.2025.05.023
  
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sciencedirect.com/science/article/pii/S1074761325002444
May 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

hiPSC-neurons recapitulate the subtype-specific cell intrinsic nature of susceptibility to neurodegenerative disease-relevant aggregation

1
1. scibot 21 May 2025
  
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  AB_2314654
  
  DOI: 10.1186/s40478-025-02000-4
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12087151/
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p16-expressing microglia and endothelial cells promote tauopathy and neurovascular abnormalities in PS19 mice

1
1. scibot 18 May 2025
  
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  RRID:AB_2314654
  
  DOI: 10.1016/j.neuron.2025.04.020
  
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sciencedirect.com/science/article/pii/S0896627325003034
www.cell.com www.cell.com

Alzheimer’s disease patient-derived high-molecular-weight tau impairs bursting in hippocampal neurons

1
1. scibot 16 May 2025
  
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  RRID:AB_2314654
  
  DOI: 10.1016/j.cell.2025.04.006
  
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cell.com/cell/fulltext/S0092-8674(25)00408-8
Apr 2025
link.springer.com link.springer.com

Biochemical characterization of Tau protein changes and amyloid dynamics in a novel non-transgenic rat model of tauopathy

1
1. scibot 11 Apr 2025
  
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  RRID:AD_2314654
  
  DOI: 10.1007/s00702-025-02909-z
  
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  Curator: @sjvitug
  
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link.springer.com/article/10.1007/s00702-025-02909-z
Mar 2025
www.sciencedirect.com www.sciencedirect.com

TDP-43 seeding induces cytoplasmic aggregation heterogeneity and nuclear loss of function of TDP-43

1
1. scibot 29 Mar 2025
  
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  RRID:AB_2314654
  
  DOI: 10.1016/j.neuron.2025.03.004
  
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sciencedirect.com/science/article/pii/S089662732500176X
Oct 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

3D model for human glia conversion into subtype-specific neurons, including dopamine neurons

1
1. scibot 03 Oct 2024
  
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  RRID:AB_2314654
  
  DOI: 10.1016/j.crmeth.2024.100845
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11440053/
www.sciencedirect.com www.sciencedirect.com

Alzheimer’s disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model

1
1. scibot 02 Oct 2024
  
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  AB_2314654
  
  DOI: 10.1016/j.neuron.2024.09.006
  
  Resource: (Thermo Fisher Scientific Cat# MN1000, RRID:AB_2314654)
  
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sciencedirect.com/science/article/pii/S0896627324006548
Aug 2024
www.cell.com www.cell.com

Neurofibrillary tangle-bearing neurons have reduced risk of cell death in mice with Alzheimer’s pathology

1
1. scibot 18 Aug 2024
  
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  RRID:AB_2314654
  
  DOI: 10.1016/j.celrep.2024.114574
  
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cell.com/cell-reports/fulltext/S2211-1247(24)00903-3
molecularneurodegeneration.biomedcentral.com molecularneurodegeneration.biomedcentral.com

Plaque associated microglia hyper-secrete extracellular vesicles and accelerate tau propagation in a humanized APP mouse model

1
1. scibot 02 Aug 2024
  
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  pSer202/pSer205 tau
  
  DOI: 10.1186/s13024-021-00440-9
  
  Resource: (Thermo Fisher Scientific Cat# MN1000, RRID:AB_2314654)
  
  Curator: @Naa003
  
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  RRIDCUR:Missing RRID:AB_2314654
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molecularneurodegeneration.biomedcentral.com/article/10.1186/s13024-021-00440-9
May 2024
52.53.155.43 52.53.155.43

Mark4 ablation attenuates pathological phenotypes in a mouse model of tauopathy

1
1. scibot 03 May 2024
  
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  AB_2314654
  
  DOI: 10.1093/braincomms/fcae136
  
  Resource: (Thermo Fisher Scientific Cat# MN1000, RRID:AB_2314654)
  
  Curator: @scibot
  
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52.53.155.43/88fa296b3636c5d5cfc19001d0db77c2230ebd0a/fcae136-html.html
Apr 2024
www.sciencedirect.com www.sciencedirect.com

Human iPSC 4R tauopathy model uncovers modifiers of tau propagation

1
1. scibot 09 Apr 2024
  
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  RRID:AB_2314654
  
  DOI: 10.1016/j.cell.2024.03.015
  
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sciencedirect.com/science/article/pii/S0092867424003064
link.springer.com link.springer.com

Landscape of brain myeloid cell transcriptome along the spatiotemporal progression of Alzheimer’s disease reveals distinct sequential responses to Aβ and tau

1
1. scibot 03 Apr 2024
  
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  RRID:AB_2314654
  
  DOI: 10.1007/s00401-024-02704-2
  
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link.springer.com/article/10.1007/s00401-024-02704-2
Mar 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

LRRK2 kinase inhibition reverses G2019S mutation-dependent effects on tau pathology progression

1
1. scibot 06 Mar 2024
  
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  RRID:AB_2314654
  
  DOI: 10.1186/s40035-024-00403-2
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10910783/
Jan 2024
onlinelibrary.wiley.com onlinelibrary.wiley.com

Acetylated tau exacerbates apoptosis by disturbing mitochondrial dynamics in HEK293 cells

1
1. scibot 31 Jan 2024
  
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  RRID:AB_2314654
  
  DOI: 10.1111/jnc.16053
  
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onlinelibrary.wiley.com/doi/10.1111/jnc.16053
Oct 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Determinants of astrocytic pathology in stem cell models of primary tauopathies

1
1. scibot 09 Oct 2023
  
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  RRID:AB_2314654
  
  DOI: 10.1186/s40478-023-01655-1
  
  Resource: (Thermo Fisher Scientific Cat# MN1000, RRID:AB_2314654)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10557325/
Aug 2023
www.sciencedirect.com www.sciencedirect.com

IGFBPL1 is a master driver of microglia homeostasis and resolution of neuroinflammation in glaucoma and brain tauopathy

1
1. scibot 03 Aug 2023
  
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  RRID:AB_2314654
  
  DOI: 10.1016/j.celrep.2023.112889
  
  Resource: (Thermo Fisher Scientific Cat# MN1000, RRID:AB_2314654)
  
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sciencedirect.com/science/article/pii/S2211124723009002
Jul 2023
www.sciencedirect.com www.sciencedirect.com

Super-resolution imaging unveils the self-replication of tau aggregates upon seeding

1
1. scibot 05 Jul 2023
  
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  RRID:AB_2314654
  
  DOI: 10.1016/j.celrep.2023.112725
  
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sciencedirect.com/science/article/pii/S2211124723007362
Jun 2023
www.sciencedirect.com www.sciencedirect.com

Increased G3BP2-Tau interaction in tauopathies is a natural defense against Tau aggregation

1
1. scibot 29 Jun 2023
  
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  RRID:AB_2314654
  
  DOI: 10.1016/j.neuron.2023.05.033
  
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sciencedirect.com/science/article/pii/S0896627323004348
www.biorxiv.org www.biorxiv.org

KIBRA repairs synaptic plasticity and promotes resilience to tauopathy-related memory loss

1
1. scibot 23 Jun 2023
  
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  RRID:AB_2314654
  
  DOI: 10.1101/2023.06.12.543777
  
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biorxiv.org/content/10.1101/2023.06.12.543777v1
Mar 2023
www.mdpi.com www.mdpi.com

Anterograde and Retrograde Propagation of Inoculated Human Tau Fibrils and Tau Oligomers in a Non-Transgenic Rat Tauopathy Model

1
1. scibot 30 Mar 2023
  
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  RRID:AD_2314654
  
  DOI: 10.3390/biomedicines11041004
  
  Resource: (Thermo Fisher Scientific Cat# MN1000, RRID:AB_2314654)
  
  Curator: @namburiamit
  
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  RRIDCUR:Unresolved RRID:AB_2314654
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mdpi.com/2227-9059/11/4/1004
www.sciencedirect.com www.sciencedirect.com

Neuronal identity defines α-synuclein and tau toxicity

1
1. scibot 28 Mar 2023
  
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  RRID:AB_2314654
  
  DOI: 10.1016/j.neuron.2023.02.033
  
  Resource: (Thermo Fisher Scientific Cat# MN1000, RRID:AB_2314654)
  
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sciencedirect.com/science/article/pii/S0896627323001666
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Characterization of the Tau Interactome in Human Brain Reveals Isoform-Dependent Interaction with 14-3-3 Family Proteins

1
1. scibot 26 Mar 2023
  
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  RRID:AB_2314654
  
  DOI: 10.1523/ENEURO.0503-22.2023
  
  Resource: (Thermo Fisher Scientific Cat# MN1000, RRID:AB_2314654)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10035768/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Selective dysfunction of fast-spiking inhibitory interneurons and disruption of perineuronal nets in a tauopathy mouse model

1
1. scibot 24 Mar 2023
  
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  RRID:AB_2314654
  
  DOI: 10.1016/j.isci.2023.106342
  
  Resource: (Thermo Fisher Scientific Cat# MN1000, RRID:AB_2314654)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10031157/
www.sciencedirect.com www.sciencedirect.com

Real-time mechanisms of exacerbated synaptic remodeling by microglia in acute models of systemic inflammation and tauopathy

1
1. scibot 10 Mar 2023
  
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  RRID:AB_2314654
  
  DOI: 10.1016/j.bbi.2023.02.023
  
  Resource: (Thermo Fisher Scientific Cat# MN1000, RRID:AB_2314654)
  
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sciencedirect.com/science/article/pii/S0889159123000545
Dec 2022
www.sciencedirect.com www.sciencedirect.com

In vitro-derived medium spiny neurons recapitulate human striatal development and complexity at single-cell resolution

1
1. scibot 20 Dec 2022
  
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  RRID:AB_2314654
  
  DOI: 10.1016/j.crmeth.2022.100367
  
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sciencedirect.com/science/article/pii/S2667237522002697
Oct 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

CASK loss of function differentially regulates neuronal maturation and synaptic function in human induced cortical excitatory neurons

1
1. scibot 19 Oct 2022
  
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  RRID:AB_2314654
  
  DOI: 10.1016/j.isci.2022.105187
  
  Resource: (Thermo Fisher Scientific Cat# MN1000, RRID:AB_2314654)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9574418/
Sep 2022
www.sciencedirect.com www.sciencedirect.com

A next-generation iPSC-derived forebrain organoid model of tauopathy with tau fibrils by AAV-mediated gene transfer

1
1. scibot 11 Sep 2022
  
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  RRID:AB_2314654
  
  DOI: 10.1016/j.crmeth.2022.100289
  
  Resource: (Thermo Fisher Scientific Cat# MN1000, RRID:AB_2314654)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S2667237522001710
Jun 2022
www.sciencedirect.com www.sciencedirect.com

Sustained Trem2 stabilization accelerates microglia heterogeneity and Aβ pathology in a mouse model of Alzheimer’s disease

1
1. scibot 03 Jun 2022
  
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  RRID:AB_2314654
  
  DOI: 10.1016/j.celrep.2022.110883
  
  Resource: (Thermo Fisher Scientific Cat# MN1000, RRID:AB_2314654)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S2211124722006581
May 2022
link.springer.com link.springer.com

Alzheimer risk gene product Pyk2 suppresses tau phosphorylation and phenotypic effects of tauopathy

1
1. scibot 05 May 2022
  
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  RRID:AB_2314654
  
  DOI: 10.1186/s13024-022-00526-y
  
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link.springer.com/article/10.1186/s13024-022-00526-y
Mar 2022
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Endosomal phosphatidylinositol 3-phosphate controls synaptic vesicle cycling and neurotransmission

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1. scibot 25 Mar 2022
  
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  RRID:AB_2314654
  
  DOI: 10.15252/embj.2021109352
  
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embopress.org/doi/abs/10.15252/embj.2021109352
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Familial natural short sleep mutations reduce Alzheimer pathology in mice

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1. scibot 18 Mar 2022
  
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  RRID:AB_2314654
  
  DOI: 10.1016/j.isci.2022.103964
  
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sciencedirect.com/science/article/pii/S2589004222002346
Jan 2022
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Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration

1
1. scibot 21 Jan 2022
  
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  RRID:AB_2314654
  
  DOI: 10.1016/j.cell.2021.12.041
  
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sciencedirect.com/science/article/pii/S0092867421015634
Aug 2021
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Untitled document

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1. scibot 10 Aug 2021
  
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  RRID:AB_2314654
  
  DOI: 10.1016/j.celrep.2018.12.085
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6335264/
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Untitled document

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1. scibot 09 Aug 2021
  
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  DOI: 10.3233/JAD-180556
  
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content.iospress.com/articles/journal-of-alzheimers-disease/jad180556
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ELAVL4, splicing, and glutamatergic dysfunction precede neuron loss in MAPT mutation cerebral organoids

1
1. scibot 01 Aug 2021
  
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  RRID:AB_2314654
  
  DOI: 10.1016/j.cell.2021.07.003
  
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sciencedirect.com/science/article/pii/S0092867421008291
Jul 2021
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Changes in the Synaptic Proteome in Tauopathy and Rescue of Tau-Induced Synapse Loss by C1q Antibodies

1
1. scibot 30 Jul 2021
  
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  RRID:AB_2314654
  
  DOI: 10.1016/j.neuron.2018.10.014
  
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sciencedirect.com/science/article/pii/S0896627318309024
May 2021
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Trem2 restrains the enhancement of tau accumulation and neurodegeneration by β-amyloid pathology

1
1. scibot 08 May 2021
  
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  RRID:AB_2314654
  
  DOI: 10.1016/j.neuron.2021.02.010
  
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sciencedirect.com/science/article/pii/S0896627321000842
Apr 2021
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Chaperone-mediated autophagy prevents collapse of the neuronal metastable proteome

1
1. scibot 23 Apr 2021
  
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  RRID:AB_2314654
  
  DOI: 10.1016/j.cell.2021.03.048
  
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sciencedirect.com/science/article/pii/S0092867421003792
Feb 2021
academic.oup.com academic.oup.com

Expression of GFAP and Tau Following Blast Exposure in the Cerebral Cortex of Ferrets

1
1. scibot 19 Feb 2021
  
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  RRID:AB_2314654
  
  DOI: 10.1093/jnen/nlaa157
  
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academic.oup.com/jnen/advance-article/doi/10.1093/jnen/nlaa157/6075096
Oct 2020
onlinelibrary.wiley.com onlinelibrary.wiley.com

Tau phosphorylation by glycogen synthase kinase 3β modulates AChE expression

1
1. scibot 22 Oct 2020
  
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  RRID:AB_2314654
  
  DOI: 10.1111/jnc.15189
  
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onlinelibrary.wiley.com/doi/10.1111/jnc.15189
Sep 2020
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Tau reduction in aged mice does not impact Microangiopathy

1
1. scibot 26 Sep 2020
  
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  RRID:AB_2314654
  
  DOI: 10.1186/s40478-020-01014-4
  
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Fyn Kinase Controls Tau Aggregation In Vivo

1
1. scibot 17 Sep 2020
  
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  RRID:AB_2314654
  
  DOI: 10.1016/j.celrep.2020.108045
  
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Increased Tau Expression Correlates with Neuronal Maturation in the Developing Human Cerebral Cortex

1
1. scibot 05 Sep 2020
  
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  RRID:AB_2314654
  
  DOI: 10.1523/ENEURO.0058-20.2020
  
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eneuro.org/content/7/3/ENEURO.0058-20.2020
Jan 2020
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Pathogenic Tau Impairs Axon Initial Segment Plasticity and Excitability Homeostasis

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2314654
  
  DOI: 10.1016/j.neuron.2019.08.008
  
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sciencedirect.com/science/article/pii/S0896627319306920
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CRISPR Interference-Based Platform for Multimodal Genetic Screens in Human iPSC-Derived Neurons

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2314654
  
  DOI: 10.1016/j.neuron.2019.07.014
  
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sciencedirect.com/science/article/pii/S0896627319306403
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Untitled document

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.celrep.2018.12.085
  
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sciencedirect.com/science/article/pii/S221112471832045X
Nov 2018
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Structural Basis for Recognition of a Unique Epitope by a Human Anti-tau Antibody

1
1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S0969212618303265
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Untitled document

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1. scibot 05 Nov 2018
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6161320/
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Living Neurons with Tau Filaments Aberrantly Expose Phosphatidylserine and Are Phagocytosed by Microglia

1
1. scibot 05 Nov 2018
  
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  RRID:AB_2314654
  
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sciencedirect.com/science/article/pii/S2211124718311902