44 Matching Annotations
  1. Oct 2024
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    3D model for human glia conversion into subtype-specific neurons, including dopamine neurons
    1
    1. scibot 03 Oct 2024
      RRID:AB_2314654

      DOI: 10.1016/j.crmeth.2024.100845

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    ncbi.nlm.nih.gov/pmc/articles/PMC11440053/
  3. www.sciencedirect.com www.sciencedirect.com
    Alzheimer’s disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model
    1
    1. scibot 02 Oct 2024
      AB_2314654

      DOI: 10.1016/j.neuron.2024.09.006

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    sciencedirect.com/science/article/pii/S0896627324006548
  4. Aug 2024
  5. www.cell.com www.cell.com
    Neurofibrillary tangle-bearing neurons have reduced risk of cell death in mice with Alzheimer’s pathology
    1
    1. scibot 18 Aug 2024
      RRID:AB_2314654

      DOI: 10.1016/j.celrep.2024.114574

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    cell.com/cell-reports/fulltext/S2211-1247(24)00903-3
  6. molecularneurodegeneration.biomedcentral.com molecularneurodegeneration.biomedcentral.com
    Plaque associated microglia hyper-secrete extracellular vesicles and accelerate tau propagation in a humanized APP mouse model
    1
    1. scibot 02 Aug 2024
      pSer202/pSer205 tau

      DOI: 10.1186/s13024-021-00440-9

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    molecularneurodegeneration.biomedcentral.com/article/10.1186/s13024-021-00440-9
  7. May 2024
  8. 52.53.155.43 52.53.155.43
    Mark4 ablation attenuates pathological phenotypes in a mouse model of tauopathy
    1
    1. scibot 03 May 2024
      AB_2314654

      DOI: 10.1093/braincomms/fcae136

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    52.53.155.43/88fa296b3636c5d5cfc19001d0db77c2230ebd0a/fcae136-html.html
  9. Apr 2024
  10. www.sciencedirect.com www.sciencedirect.com
    Human iPSC 4R tauopathy model uncovers modifiers of tau propagation
    1
    1. scibot 09 Apr 2024
      RRID:AB_2314654

      DOI: 10.1016/j.cell.2024.03.015

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    sciencedirect.com/science/article/pii/S0092867424003064
  11. link.springer.com link.springer.com
    Landscape of brain myeloid cell transcriptome along the spatiotemporal progression of Alzheimer’s disease reveals distinct sequential responses to Aβ and tau
    1
    1. scibot 03 Apr 2024
      RRID:AB_2314654

      DOI: 10.1007/s00401-024-02704-2

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    link.springer.com/article/10.1007/s00401-024-02704-2
  12. Mar 2024
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    LRRK2 kinase inhibition reverses G2019S mutation-dependent effects on tau pathology progression
    1
    1. scibot 06 Mar 2024
      RRID:AB_2314654

      DOI: 10.1186/s40035-024-00403-2

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    ncbi.nlm.nih.gov/pmc/articles/PMC10910783/
  14. Jan 2024
  15. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Acetylated tau exacerbates apoptosis by disturbing mitochondrial dynamics in HEK293 cells
    1
    1. scibot 31 Jan 2024
      RRID:AB_2314654

      DOI: 10.1111/jnc.16053

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    onlinelibrary.wiley.com/doi/10.1111/jnc.16053
  16. Oct 2023
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Determinants of astrocytic pathology in stem cell models of primary tauopathies
    1
    1. scibot 09 Oct 2023
      RRID:AB_2314654

      DOI: 10.1186/s40478-023-01655-1

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    ncbi.nlm.nih.gov/pmc/articles/PMC10557325/
  18. Aug 2023
  19. www.sciencedirect.com www.sciencedirect.com
    IGFBPL1 is a master driver of microglia homeostasis and resolution of neuroinflammation in glaucoma and brain tauopathy
    1
    1. scibot 03 Aug 2023
      RRID:AB_2314654

      DOI: 10.1016/j.celrep.2023.112889

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    sciencedirect.com/science/article/pii/S2211124723009002
  20. Jul 2023
  21. www.sciencedirect.com www.sciencedirect.com
    Super-resolution imaging unveils the self-replication of tau aggregates upon seeding
    1
    1. scibot 05 Jul 2023
      RRID:AB_2314654

      DOI: 10.1016/j.celrep.2023.112725

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    sciencedirect.com/science/article/pii/S2211124723007362
  22. Jun 2023
  23. www.sciencedirect.com www.sciencedirect.com
    Increased G3BP2-Tau interaction in tauopathies is a natural defense against Tau aggregation
    1
    1. scibot 29 Jun 2023
      RRID:AB_2314654

      DOI: 10.1016/j.neuron.2023.05.033

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    sciencedirect.com/science/article/pii/S0896627323004348
  24. www.biorxiv.org www.biorxiv.org
    KIBRA repairs synaptic plasticity and promotes resilience to tauopathy-related memory loss
    1
    1. scibot 23 Jun 2023
      RRID:AB_2314654

      DOI: 10.1101/2023.06.12.543777

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    biorxiv.org/content/10.1101/2023.06.12.543777v1
  25. Mar 2023
  26. www.mdpi.com www.mdpi.com
    Anterograde and Retrograde Propagation of Inoculated Human Tau Fibrils and Tau Oligomers in a Non-Transgenic Rat Tauopathy Model
    1
    1. scibot 30 Mar 2023
      RRID:AD_2314654

      DOI: 10.3390/biomedicines11041004

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      Curator: @namburiamit

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    mdpi.com/2227-9059/11/4/1004
  27. www.sciencedirect.com www.sciencedirect.com
    Neuronal identity defines α-synuclein and tau toxicity
    1
    1. scibot 28 Mar 2023
      RRID:AB_2314654

      DOI: 10.1016/j.neuron.2023.02.033

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    sciencedirect.com/science/article/pii/S0896627323001666
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Characterization of the Tau Interactome in Human Brain Reveals Isoform-Dependent Interaction with 14-3-3 Family Proteins
    1
    1. scibot 26 Mar 2023
      RRID:AB_2314654

      DOI: 10.1523/ENEURO.0503-22.2023

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    ncbi.nlm.nih.gov/pmc/articles/PMC10035768/
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Selective dysfunction of fast-spiking inhibitory interneurons and disruption of perineuronal nets in a tauopathy mouse model
    1
    1. scibot 24 Mar 2023
      RRID:AB_2314654

      DOI: 10.1016/j.isci.2023.106342

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    ncbi.nlm.nih.gov/pmc/articles/PMC10031157/
  30. www.sciencedirect.com www.sciencedirect.com
    Real-time mechanisms of exacerbated synaptic remodeling by microglia in acute models of systemic inflammation and tauopathy
    1
    1. scibot 10 Mar 2023
      RRID:AB_2314654

      DOI: 10.1016/j.bbi.2023.02.023

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    sciencedirect.com/science/article/pii/S0889159123000545
  31. Dec 2022
  32. www.sciencedirect.com www.sciencedirect.com
    In vitro-derived medium spiny neurons recapitulate human striatal development and complexity at single-cell resolution
    1
    1. scibot 20 Dec 2022
      RRID:AB_2314654

      DOI: 10.1016/j.crmeth.2022.100367

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    sciencedirect.com/science/article/pii/S2667237522002697
  33. Oct 2022
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CASK loss of function differentially regulates neuronal maturation and synaptic function in human induced cortical excitatory neurons
    1
    1. scibot 19 Oct 2022
      RRID:AB_2314654

      DOI: 10.1016/j.isci.2022.105187

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    ncbi.nlm.nih.gov/pmc/articles/PMC9574418/
  35. Sep 2022
  36. www.sciencedirect.com www.sciencedirect.com
    A next-generation iPSC-derived forebrain organoid model of tauopathy with tau fibrils by AAV-mediated gene transfer
    1
    1. scibot 11 Sep 2022
      RRID:AB_2314654

      DOI: 10.1016/j.crmeth.2022.100289

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    sciencedirect.com/science/article/pii/S2667237522001710
  37. Jun 2022
  38. www.sciencedirect.com www.sciencedirect.com
    Sustained Trem2 stabilization accelerates microglia heterogeneity and Aβ pathology in a mouse model of Alzheimer’s disease
    1
    1. scibot 03 Jun 2022
      RRID:AB_2314654

      DOI: 10.1016/j.celrep.2022.110883

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    sciencedirect.com/science/article/pii/S2211124722006581
  39. May 2022
  40. link.springer.com link.springer.com
    Alzheimer risk gene product Pyk2 suppresses tau phosphorylation and phenotypic effects of tauopathy
    1
    1. scibot 05 May 2022
      RRID:AB_2314654

      DOI: 10.1186/s13024-022-00526-y

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    link.springer.com/article/10.1186/s13024-022-00526-y
  41. Mar 2022
  42. www.embopress.org www.embopress.org
    Endosomal phosphatidylinositol 3-phosphate controls synaptic vesicle cycling and neurotransmission
    1
    1. scibot 25 Mar 2022
      RRID:AB_2314654

      DOI: 10.15252/embj.2021109352

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    embopress.org/doi/abs/10.15252/embj.2021109352
  43. www.sciencedirect.com www.sciencedirect.com
    Familial natural short sleep mutations reduce Alzheimer pathology in mice
    1
    1. scibot 18 Mar 2022
      RRID:AB_2314654

      DOI: 10.1016/j.isci.2022.103964

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    sciencedirect.com/science/article/pii/S2589004222002346
  44. Jan 2022
  45. www.sciencedirect.com www.sciencedirect.com
    Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration
    1
    1. scibot 21 Jan 2022
      RRID:AB_2314654

      DOI: 10.1016/j.cell.2021.12.041

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    sciencedirect.com/science/article/pii/S0092867421015634
  46. Aug 2021
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    1. scibot 10 Aug 2021
      RRID:AB_2314654

      DOI: 10.1016/j.celrep.2018.12.085

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    ncbi.nlm.nih.gov/pmc/articles/PMC6335264/
  48. content.iospress.com content.iospress.com
    Untitled document
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    1. scibot 09 Aug 2021
      AB_2314654

      DOI: 10.3233/JAD-180556

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    content.iospress.com/articles/journal-of-alzheimers-disease/jad180556
  49. www.sciencedirect.com www.sciencedirect.com
    ELAVL4, splicing, and glutamatergic dysfunction precede neuron loss in MAPT mutation cerebral organoids
    1
    1. scibot 01 Aug 2021
      RRID:AB_2314654

      DOI: 10.1016/j.cell.2021.07.003

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    sciencedirect.com/science/article/pii/S0092867421008291
  50. Jul 2021
  51. www.sciencedirect.com www.sciencedirect.com
    Changes in the Synaptic Proteome in Tauopathy and Rescue of Tau-Induced Synapse Loss by C1q Antibodies
    1
    1. scibot 30 Jul 2021
      RRID:AB_2314654

      DOI: 10.1016/j.neuron.2018.10.014

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    sciencedirect.com/science/article/pii/S0896627318309024
  52. May 2021
  53. www.sciencedirect.com www.sciencedirect.com
    Trem2 restrains the enhancement of tau accumulation and neurodegeneration by β-amyloid pathology
    1
    1. scibot 08 May 2021
      RRID:AB_2314654

      DOI: 10.1016/j.neuron.2021.02.010

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    sciencedirect.com/science/article/pii/S0896627321000842
  54. Apr 2021
  55. www.sciencedirect.com www.sciencedirect.com
    Chaperone-mediated autophagy prevents collapse of the neuronal metastable proteome
    1
    1. scibot 23 Apr 2021
      RRID:AB_2314654

      DOI: 10.1016/j.cell.2021.03.048

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    sciencedirect.com/science/article/pii/S0092867421003792
  56. Feb 2021
  57. academic.oup.com academic.oup.com
    Expression of GFAP and Tau Following Blast Exposure in the Cerebral Cortex of Ferrets
    1
    1. scibot 19 Feb 2021
      RRID:AB_2314654

      DOI: 10.1093/jnen/nlaa157

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    academic.oup.com/jnen/advance-article/doi/10.1093/jnen/nlaa157/6075096
  58. Oct 2020
  59. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Tau phosphorylation by glycogen synthase kinase 3β modulates AChE expression
    1
    1. scibot 22 Oct 2020
      RRID:AB_2314654

      DOI: 10.1111/jnc.15189

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    onlinelibrary.wiley.com/doi/10.1111/jnc.15189
  60. Sep 2020
  61. link.springer.com link.springer.com
    Tau reduction in aged mice does not impact Microangiopathy
    1
    1. scibot 26 Sep 2020
      RRID:AB_2314654

      DOI: 10.1186/s40478-020-01014-4

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    link.springer.com/article/10.1186/s40478-020-01014-4
  62. www.sciencedirect.com www.sciencedirect.com
    Fyn Kinase Controls Tau Aggregation In Vivo
    1
    1. scibot 17 Sep 2020
      RRID:AB_2314654

      DOI: 10.1016/j.celrep.2020.108045

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    sciencedirect.com/science/article/pii/S2211124720310305
  63. www.eneuro.org www.eneuro.org
    Increased Tau Expression Correlates with Neuronal Maturation in the Developing Human Cerebral Cortex
    1
    1. scibot 05 Sep 2020
      RRID:AB_2314654

      DOI: 10.1523/ENEURO.0058-20.2020

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    eneuro.org/content/7/3/ENEURO.0058-20.2020
  64. Jan 2020
  65. www.sciencedirect.com www.sciencedirect.com
    Pathogenic Tau Impairs Axon Initial Segment Plasticity and Excitability Homeostasis
    1
    1. scibot 13 Jan 2020
      RRID:AB_2314654

      DOI: 10.1016/j.neuron.2019.08.008

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    sciencedirect.com/science/article/pii/S0896627319306920
  66. www.sciencedirect.com www.sciencedirect.com
    CRISPR Interference-Based Platform for Multimodal Genetic Screens in Human iPSC-Derived Neurons
    1
    1. scibot 13 Jan 2020
      RRID:AB_2314654

      DOI: 10.1016/j.neuron.2019.07.014

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      Curator: @ethanbadger

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      RRID:AB_2314654 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0896627319306403
  67. www.sciencedirect.com www.sciencedirect.com
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    1. scibot 13 Jan 2020
      RRID:AB_2314654

      DOI: 10.1016/j.celrep.2018.12.085

      Resource: (Thermo Fisher Scientific Cat# MN1000, RRID:AB_2314654)

      Curator: @ethanbadger

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      RRID:AB_2314654 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S221112471832045X
  68. Nov 2018
  69. www.sciencedirect.com www.sciencedirect.com
    Structural Basis for Recognition of a Unique Epitope by a Human Anti-tau Antibody
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    1. scibot 05 Nov 2018
      AB_2314654

      Curator: @Jmenke

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      (Thermo Fisher Scientific Cat# MN1000, RRID:AB_2314654)

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      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:AB_2314654 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0969212618303265
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    1. scibot 05 Nov 2018
      RRID:AB_2314654

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      (Thermo Fisher Scientific Cat# MN1000, RRID:AB_2314654)

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    ncbi.nlm.nih.gov/pmc/articles/PMC6161320/
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    Living Neurons with Tau Filaments Aberrantly Expose Phosphatidylserine and Are Phagocytosed by Microglia
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    1. scibot 05 Nov 2018
      RRID:AB_2314654

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      (Thermo Fisher Scientific Cat# MN1000, RRID:AB_2314654)

      SciCrunch record: RRID:AB_2314654

      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:AB_2314654
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    sciencedirect.com/science/article/pii/S2211124718311902