1,002 Matching Annotations
  1. Jul 2023
  2. www.sciencedirect.com www.sciencedirect.com
    Targeting endometrial inflammation in intrauterine adhesion ameliorates endometrial fibrosis by priming MSCs to secrete C1INH
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    1. scibot 07 Jul 2023
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      DOI: 10.1016/j.isci.2023.107201

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    sciencedirect.com/science/article/pii/S2589004223012786
  3. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IGF1R inhibition enhances the therapeutic effects of Gq/11 inhibition in metastatic uveal melanoma progression
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    1. scibot 06 Jul 2023
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      DOI: 10.1158/1535-7163.MCT-22-0147

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    ncbi.nlm.nih.gov/pmc/articles/PMC9812929/
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    N-myc mediated translation control is a therapeutic vulnerability in medulloblastoma
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    1. scibot 06 Jul 2023
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      DOI: 10.1158/0008-5472.CAN-22-0945

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    ncbi.nlm.nih.gov/pmc/articles/PMC9812901/
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    Macrophage-mediated extracellular matrix remodeling controls host Staphylococcus aureus susceptibility in the skin
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    1. scibot 06 Jul 2023
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      DOI: 10.1016/j.immuni.2023.06.006

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    sciencedirect.com/science/article/pii/S1074761323002637
  6. Jun 2023
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    ECPAS/Ecm29-mediated 26S proteasome disassembly is an adaptive response to glucose starvation
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    1. scibot 29 Jun 2023
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    sciencedirect.com/science/article/pii/S221112472300712X
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    Identification of XAF1 as an endogenous AKT inhibitor
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    1. scibot 29 Jun 2023
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    sciencedirect.com/science/article/pii/S2211124723007015
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SRSF10 regulates proliferation of neural progenitor cells and affects neurogenesis in developing mouse neocortex
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    1. scibot 24 Jun 2023
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    ncbi.nlm.nih.gov/pmc/articles/PMC10285642/
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Uterine-specific Ezh2 deletion enhances stromal cell senescence and impairs placentation, resulting in pregnancy loss
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    ncbi.nlm.nih.gov/pmc/articles/PMC10285549/
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    The potential therapeutic regimen for overcoming resistance to osimertinib due to rare mutations in NSCLC
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    1. scibot 24 Jun 2023
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    sciencedirect.com/science/article/pii/S2589004223011823
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    Peroxisome proliferator activated receptor-γ in osteoblasts controls bone formation and fat mass by regulating sclerostin expression
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    1. scibot 23 Jun 2023
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    sciencedirect.com/science/article/pii/S2589004223010763
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    Antiandrogen treatment induces stromal cell reprogramming to promote castration resistance in prostate cancer
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    1. scibot 23 Jun 2023
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    sciencedirect.com/science/article/pii/S1535610823001836
  14. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Single-cell RNA-seq uncovers novel metabolic functions of Schwann cells beyond myelination
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    1. scibot 22 Jun 2023
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15877
  15. www.biorxiv.org www.biorxiv.org
    Involvement of a serotonin/GLP-1 circuit in adolescent isolation-induced diabetes
    1
    1. scibot 22 Jun 2023
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      DOI: 10.1101/2023.06.12.544498

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    biorxiv.org/content/10.1101/2023.06.12.544498v1
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    Acetate controls endothelial-to-mesenchymal transition
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    1. scibot 21 Jun 2023
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    sciencedirect.com/science/article/pii/S1550413123002036
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    Dynamic interplay between IL-1 and WNT pathways in regulating dermal adipocyte lineage cells during skin development and wound regeneration
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    1. scibot 21 Jun 2023
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    sciencedirect.com/science/article/pii/S2211124723006587
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    MEK inhibitor and anti-EGFR antibody overcome sotorasib resistance signals and enhance its antitumor effect in colorectal cancer cells
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    1. scibot 21 Jun 2023
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      DOI: 10.1016/j.canlet.2023.216264

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    sciencedirect.com/science/article/pii/S030438352300215X
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    Advanced human iPSC-based preclinical model for Parkinson’s disease with optogenetic alpha-synuclein aggregation
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    1. scibot 21 Jun 2023
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      DOI: 10.1016/j.stem.2023.05.015

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    sciencedirect.com/science/article/pii/S1934590923002114
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    N6-methyl-2′-deoxyadenosine promotes self-renewal of BFU-E progenitor in erythropoiesis
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    1. scibot 08 Jun 2023
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      DOI: 10.1016/j.isci.2023.106924

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    ncbi.nlm.nih.gov/pmc/articles/PMC10239700/
  21. www.nature.com www.nature.com
    Evaluation of therapeutic PD-1 antibodies by an advanced single-molecule imaging system detecting human PD-1 microclusters
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    1. scibot 08 Jun 2023
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      DOI: 10.1038/s41467-023-38512-7

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    nature.com/articles/s41467-023-38512-7
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DAB2IP Is a Bifunctional Tumor Suppressor That Regulates Wild-Type RAS and Inflammatory Cascades in KRAS Mutant Colon Cancer
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    1. scibot 07 Jun 2023
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      DOI: 10.1158/0008-5472.CAN-22-0370

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    ncbi.nlm.nih.gov/pmc/articles/PMC10236151/
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hypomorphism of a Novel Long ERα Isoform Causes Severe Reproductive Dysfunctions in Female Mice
    1
    1. scibot 03 Jun 2023
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      DOI: 10.1210/endocr/bqac160

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    ncbi.nlm.nih.gov/pmc/articles/PMC10233398/
  24. aacrjournals.org aacrjournals.org
    Dysregulation of mitochondrial translation caused by CBFB deficiency cooperates with mutant PIK3CA and is a vulnerability in breast cancer
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    1. scibot 03 Jun 2023
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      DOI: 10.1158/0008-5472.CAN-22-2525

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    aacrjournals.org/cancerres/article/83/8/1280/725099/Dysregulation-of-Mitochondrial-Translation-Caused
  25. aacrjournals.org aacrjournals.org
    RBM10 loss promotes EGFR-driven lung cancer and confers sensitivity to spliceosome inhibition
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    1. scibot 03 Jun 2023
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    aacrjournals.org/cancerres/article/83/9/1490/726058/RBM10-Loss-Promotes-EGFR-Driven-Lung-Cancer-and
  26. www.cell.com www.cell.com
    Secreted Akkermansia muciniphila threonyl-tRNA synthetase functions to monitor and modulate immune homeostasis
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    1. scibot 03 Jun 2023
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      DOI: 10.1016/j.chom.2023.05.007

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    cell.com/cell-host-microbe/fulltext/S1931-3128(23)00200-7
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    INPP5D modulates TREM2 loss-of-function phenotypes in a β-amyloidosis mouse model
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      DOI: 10.1016/j.isci.2023.106375

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    ncbi.nlm.nih.gov/pmc/articles/PMC10074152/
  28. www.sciencedirect.com www.sciencedirect.com
    Genetic deletion of skeletal muscle iPLA2γ results in mitochondrial dysfunction, muscle atrophy and alterations in whole-body energy metabolism
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    1. scibot 02 Jun 2023
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      DOI: 10.1016/j.isci.2023.106895

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    sciencedirect.com/science/article/pii/S2589004223009720
  29. academic.oup.com academic.oup.com
    Increased fibrosis in white adipose tissue of male and female bGH transgenic mice appears independent of TGF-β action
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    1. scibot 02 Jun 2023
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      DOI: 10.1210/endocr/bqad038

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    academic.oup.com/endo/article/164/5/bqad038/7069260
  30. academic.oup.com academic.oup.com
    Cadmium-induced Sertoli cell injury through p38-MAPK and related signaling proteins – a study by RNA sequencing
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      DOI: 10.1210/endocr/bqad045

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    academic.oup.com/endo/article/164/6/bqad045/7079002
  31. onlinelibrary.wiley.com onlinelibrary.wiley.com
    The activation of GIP/GIPR axis via Sonic hedgehog signaling promotes the bridging of gapped nerves in sciatic nerve injury
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      DOI: 10.1111/jnc.15816

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    onlinelibrary.wiley.com/doi/10.1111/jnc.15816
  32. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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      DOI: 10.1111/bph.16080

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16080
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      DOI: 10.1111/bph.16069

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  34. May 2023
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Injury-induced activation of the endocannabinoid system promotes axon regeneration
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    ncbi.nlm.nih.gov/pmc/articles/PMC10205787/
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lacking ARHGAP25 mitigates the symptoms of autoantibody-induced arthritis in mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC10208528/
  37. www.sciencedirect.com www.sciencedirect.com
    Exhaustion-associated cholesterol deficiency dampens the cytotoxic arm of antitumor immunity
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    sciencedirect.com/science/article/pii/S1535610823001423
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    Context-dependent activation of STING-interferon signaling by CD11b agonists enhances anti-tumor immunity
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    sciencedirect.com/science/article/pii/S1535610823001629
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    Actuation of single downstream nodes in growth factor network steers immune cell migration
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    sciencedirect.com/science/article/pii/S1534580723001958
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    Targeting of Annexin A1 in Tumor-associated Macrophages as a Therapeutic Strategy for Hepatocellular Carcinoma
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    sciencedirect.com/science/article/pii/S0006295223002034
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    Salivary gland cancer organoids are valid for preclinical genotype-oriented medical precision trials
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    sciencedirect.com/science/article/pii/S2589004223007721
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    Trigeminal nerve derived-substance P regulates limbal stem cells by the PI3K-AKT pathway
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    sciencedirect.com/science/article/pii/S2589004223007654
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    Cancer-cell-derived fumarate suppresses the anti-tumor capacity of CD8+ T cells in the tumor microenvironment
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    RASGRF1 Fusions Activate Oncogenic RAS Signaling and Confer Sensitivity to MEK Inhibition
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    Calcium released by osteoclastic resorption stimulates autocrine/paracrine activities in local osteogenic cells to promote coupled bone formation
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    A living biobank of patient-derived ductal carcinoma in situ mouse-intraductal xenografts identifies risk factors for invasive progression
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    Deficiency of MicroRNA-23-27-24 Clusters Exhibits the Impairment of Myelination in the Central Nervous System
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    Optimal HSF1 activation in response to acute cold stress in BAT requires nuclear TXNIP
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    IGFBP3 induced by the TGF-β/EGFRvIII transactivation contributes to the malignant phenotype of glioblastoma
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    Deficiency of MicroRNA-23-27-24 Clusters Exhibits the Impairment of Myelination in the Central Nervous System
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    Malonylation of Acetyl-CoA carboxylase 1 promotes hepatic steatosis and is attenuated by ketogenic diet in NAFLD
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    Site-1 protease inhibits mitochondrial respiration by controlling the TGF-β target gene Mss51
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    IFNγ blockade in capillary leak site improves tumour chemotherapy by inhibiting lactate-induced endocytosis of vascular endothelial-cadherins
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    Metformin Prevents Endothelial Oxidative Stress and Microvascular Insulin Resistance during Obesity Development in Male Rats
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    Loss of E-cadherin Induces IGF1R Activation and Reveals a Targetable Pathway in Invasive Lobular Breast Carcinoma
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  128. www.science.org www.science.org
    Cross-talk between TSC2 and the extracellular matrix controls pulmonary vascular proliferation and pulmonary hypertension
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    Exercise postconditioning reduces ischemic injury via suppression of cerebral gluconeogenesis in rats
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    Serial profiling of circulating tumor DNA identifies dynamic evolution of clinically actionable genomic alterations in high-risk neuroblastoma
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  131. www.mdpi.com www.mdpi.com
    The Neuroprotective Effects of Arecae Pericarpium against Glutamate-Induced HT22 Cell Cytotoxicity
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    Celecoxib activates autophagy by inhibiting the mTOR signaling pathway and prevents apoptosis in nucleus pulposus cells
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    Bistable insulin response: The win-win solution for glycemic control
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    Morusin Protected Ruminal Epithelial Cells against Lipopolysaccharide-Induced Inflammation through Inhibiting EGFR-AKT/NF-κB Signaling and Improving Barrier Functions
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    Reelin regulates the migration of late-born hippocampal CA1 neurons via cofilin phosphorylation
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    Acute changes in systemic glycemia gate access and action of GLP-1R agonist on brain structures controlling energy homeostasis
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    Neuroprotective Effects of Neuropeptide Y on Human Neuroblastoma SH-SY5Y Cells in Glutamate Excitotoxicity and ER Stress Conditions
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    Bcl-xL inhibition radiosensitizes PIK3CA/PTEN wild-type triple negative breast cancers with low Mcl-1 expression
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    A ketogenic diet in combination with gemcitabine increases survival in pancreatic cancer KPC mice
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    Platelet p110β mediates platelet-leukocyte interaction and curtails bacterial dissemination in pneumococcal pneumonia
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    NF1 loss of function as an alternative initiating event in pancreatic ductal adenocarcinoma
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    Dual anti-angiogenic and anti-metastatic activity of myriocin synergistically enhances the anti-tumor activity of cisplatin
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    Angiotensin II regulates mitochondrial mTOR pathway activity dependent on acyl CoA synthetase 4 in adrenocortical cells
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    Arid1a loss potentiates pancreatic β-cell regeneration through activation of EGF signaling
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    Simultaneous SGLT2 inhibition and caloric restriction improves insulin resistance and kidney function in OLETF rats
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  149. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    Granulosa Cell Dysfunction Is Associated with Diminished Ovarian Response in FMR1 Premutation Carriers
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    Exploring visceral and subcutaneous adipose tissue secretomes in human obesity: implications for metabolic disease
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    TREM2 drives microglia response to amyloid-β via SYK-dependent and -independent pathways
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    Phosphoproteomic mapping reveals distinct signaling actions and activation of muscle protein synthesis by Isthmin-1
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    COMPREHENSIVE DRUG RESPONSE PROFILING AND PAN-OMIC ANALYSIS IDENTIFIED THERAPEUTIC CANDIDATES AND PROGNOSTIC BIOMARKERS FOR ASIAN CHOLANGIOCARCINOMA
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    Spatial modeling reveals nuclear phosphorylation and subcellular shuttling of YAP upon drug-induced liver injury
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    Vps37a regulates hepatic glucose production by controlling glucagon receptor localization to endosomes
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    The rheumatoid arthritis drug auranofin lowers leptin levels and exerts antidiabetic effects in obese mice
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    Competition for endothelial cell polarity drives vascular morphogenesis in the mouse retina
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    Siponimod exerts neuroprotective effects on the retina and... : Neural Regeneration Research
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    Schwann cells-derived exosomal miR-21 participates in high glucose regulation of neurite outgrowth
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    Hyperuricemia contributes to glucose intolerance of hepatic inflammatory macrophages and impairs the insulin signaling pathway via IRS2-proteasome degradation
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    Hepatic ER stress suppresses adipose browning through ATF4-CIRP-ANGPTL3 cascade
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    PSMG2-controlled proteasome-autophagy balance mediates the tolerance for MEK-targeted therapy in triple-negative breast cancer
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    Na/K-ATPase Suppresses LPS-Induced Pro-Inflammatory Signaling Through Lyn
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    DEPDC5-dependent mTORC1 signaling mechanisms are critical for the anti-seizure effects of acute fasting
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    BAFFR activates PI3K/AKT signaling in human naive but not in switched memory B cells through direct interactions with B cell antigen receptors
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      DOI: 10.1016/j.devcel.2022.05.013

      Resource: (Cell Signaling Technology Cat# 4060, RRID:AB_2315049)

      Curator: @scibot

      SciCrunch record: RRID:AB_2315049

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      RRID:AB_2315049
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    sciencedirect.com/science/article/pii/S1534580722003707