44 Matching Annotations
  1. Last 7 days
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    Complement C3aR deletion does not attenuate degeneration in a tauopathy model or alter acute inflammation-induced gene expression changes
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    sciencedirect.com/science/article/pii/S2211124726003918
  3. Mar 2026
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Tau PET overlap index correlation with neuropathological findings
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    pmc.ncbi.nlm.nih.gov/articles/PMC12967651/
  5. www.sciencedirect.com www.sciencedirect.com
    Tanycytic degeneration impairs tau clearance and contributes to Alzheimer’s disease pathology
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    sciencedirect.com/science/article/pii/S3051383926000010
  6. Dec 2025
  7. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    Oxidized MIF is an Alzheimer’s disease drug target relaying external risk factors to tau pathology
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    sciencedirect.com:5037/science/article/pii/S2666379125005932
  8. Jun 2025
  9. www.cell.com www.cell.com
    Computational and functional prioritization identifies genes that rescue behavior and reduce tau protein in fly and human cell models of Alzheimer disease
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    cell.com/ajhg/abstract/S0002-9297(25)00111-9
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  11. May 2025
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    hiPSC-neurons recapitulate the subtype-specific cell intrinsic nature of susceptibility to neurodegenerative disease-relevant aggregation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12087151/
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    Differential roles of human tau isoforms in the modulation of inflammation and development of neuropathology
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    sciencedirect.com/science/article/pii/S0969996125001585
  14. Apr 2025
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    Human MAPT knockin mouse models of frontotemporal dementia for the neurodegenerative research community
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    sciencedirect.com/science/article/pii/S2667237525000608
  16. Mar 2025
  17. link.springer.com link.springer.com
    Biochemical characterization of Tau protein changes and amyloid dynamics in a novel non-transgenic rat model of tauopathy
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    link.springer.com/article/10.1007/s00702-025-02909-z
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    High resolution autoradiography of [18F]MK-6240 and [18F]Flortaucipir shows similar neurofibrillary tangle binding patterns preferentially recognizing middling neurofibrillary tangle maturity
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    pmc.ncbi.nlm.nih.gov/articles/PMC11909026/
  19. Aug 2024
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tau‐mediated synaptic dysfunction is coupled with HCN channelopathy
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    ncbi.nlm.nih.gov/pmc/articles/PMC11350046/
  21. Feb 2024
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Nigrostriatal tau pathology in parkinsonism and Parkinson’s disease
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    ncbi.nlm.nih.gov/pmc/articles/PMC10834249/
  23. Oct 2023
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Behavioral and neuropathological characterization over the adult lifespan of the human tau knock-in mouse
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    ncbi.nlm.nih.gov/pmc/articles/PMC10576558/
  25. Dec 2022
  26. link.springer.com link.springer.com
    Cognitively impaired aged Octodon degus recapitulate major neuropathological features of sporadic Alzheimer’s disease
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    link.springer.com/article/10.1186/s40478-022-01481-x
  27. Nov 2022
  28. www.jneurosci.org www.jneurosci.org
    Integrity of neuronal size in the entorhinal cortex is a biologic substrate of exceptional cognitive aging
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    jneurosci.org/content/42/45/8587
  29. Jul 2022
  30. link.springer.com link.springer.com
    Anesthesia promotes acute expression of genes related to Alzheimer’s disease and latent tau aggregation in transgenic mouse models of tauopathy
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    link.springer.com/article/10.1186/s10020-022-00506-4
  31. Jun 2022
  32. link.springer.com link.springer.com
    Evidence of traumatic brain injury in headbutting bovids
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    link.springer.com/article/10.1007/s00401-022-02427-2
  33. www.sciencedirect.com www.sciencedirect.com
    Recapitulation of endogenous 4R tau expression and formation of insoluble tau in directly reprogrammed human neurons
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    sciencedirect.com/science/article/pii/S1934590922002004
  34. May 2022
  35. link.springer.com link.springer.com
    Alzheimer risk gene product Pyk2 suppresses tau phosphorylation and phenotypic effects of tauopathy
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    link.springer.com/article/10.1186/s13024-022-00526-y
  36. Apr 2022
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Reduction of Nuak1 decreases tau and reverses phenotypes in a tauopathy mouse model
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    ncbi.nlm.nih.gov/pmc/articles/PMC5745060/
  38. Mar 2022
  39. www.sciencedirect.com www.sciencedirect.com
    Homotypic fibrillization of TMEM106B across diverse neurodegenerative diseases
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    sciencedirect.com/science/article/pii/S0092867422002598
  40. Jan 2022
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Molecular Investigation of the Unfolded Protein Response in Select Human Tauopathies
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    ncbi.nlm.nih.gov/pmc/articles/PMC8764631/
  42. www.sciencedirect.com www.sciencedirect.com
    Uncovering specificity of endogenous TAU aggregation in a human iPSC-neuron TAU seeding model
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    sciencedirect.com/science/article/pii/S258900422101628X
  43. Aug 2021
  44. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Untitled document
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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.14593
  45. May 2021
  46. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Pathogenic MAPT mutations Q336H and Q336R have isoform‐dependent differences in aggregation propensity and microtubule dysfunction
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15358
  47. Mar 2021
  48. www.sciencedirect.com www.sciencedirect.com
    The AD tau core spontaneously self-assembles and recruits full-length tau to filaments
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    sciencedirect.com/science/article/pii/S2211124721001571
  49. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Suppression of tau‐induced phenotypes by vitamin E demonstrates the dissociation of oxidative stress and phosphorylation in mechanisms of tau toxicity
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15253
  50. Jan 2021
  51. www.sciencedirect.com www.sciencedirect.com
    Lowering Synaptogyrin-3 expression rescues Tau-induced memory defects and synaptic loss in the presence of microglial activation
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    sciencedirect.com/science/article/pii/S0896627320309983
  52. Dec 2020
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An in vitro bioengineered model of the human arterial neurovascular unit to study neurodegenerative diseases
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    ncbi.nlm.nih.gov/pmc/articles/PMC7678181/
  54. Sep 2020
  55. www.sciencedirect.com www.sciencedirect.com
    Posttranslational Modifications Mediate the Structural Diversity of Tauopathy Strains
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    sciencedirect.com/science/article/pii/S0092867420301082
  56. www.sciencedirect.com www.sciencedirect.com
    Management of Hsp90-Dependent Protein Folding by Small Molecules Targeting the Aha1 Co-Chaperone
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    sciencedirect.com/science/article/pii/S2451945620300337
  57. www.jneurosci.org www.jneurosci.org
    Nestin selectively facilitates the phosphorylation of the Lissencephaly-linked protein doublecortin (DCX) by cdk5/p35 to regulate growth cone morphology and Sema3a sensitivity in developing neurons.
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    jneurosci.org/content/40/19/3720
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Zonisamide Ameliorates Cognitive Impairment by Inhibiting ER Stress in a Mouse Model of Type 2 Diabetes Mellitus
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    ncbi.nlm.nih.gov/pmc/articles/PMC7367218/
  59. Jan 2020
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Microglia changes associated to Alzheimer’s disease pathology in aged chimpanzees
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    ncbi.nlm.nih.gov/pmc/articles/PMC6283685/
  61. onlinelibrary.wiley.com onlinelibrary.wiley.com
    High specificity of widely used phospho‐tau antibodies validated using a quantitative whole‐cell based assay
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    onlinelibrary.wiley.com/doi/10.1111/jnc.14830
  62. onlinelibrary.wiley.com onlinelibrary.wiley.com
    β‐amyloid and Tau Pathology in the Aging Feline Brain
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    onlinelibrary.wiley.com/doi/abs/10.1002/cne.24741
  63. www.sciencedirect.com www.sciencedirect.com
    Amyloid-Beta (Aβ) Plaques Promote Seeding and Spreading of Alpha-Synuclein and Tau in a Mouse Model of Lewy Body Disorders with Aβ Pathology
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    sciencedirect.com/science/article/pii/S0896627319308839
  64. www.sciencedirect.com www.sciencedirect.com
    Cholesterol Metabolism Is a Druggable Axis that Independently Regulates Tau and Amyloid-β in iPSC-Derived Alzheimer’s Disease Neurons
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    sciencedirect.com/science/article/pii/S1934590918306039
  65. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Untitled document
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    onlinelibrary.wiley.com/doi/full/10.1002/cne.24484
  66. Nov 2018
  67. www.jneurosci.org www.jneurosci.org
    Pathological Tau Strains from Human Brains Recapitulate the Diversity of Tauopathies in Nontransgenic Mouse Brain
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    jneurosci.org/content/37/47/11406
  68. Nov 2017
  69. www.sciencedirect.com www.sciencedirect.com
    Reduction of Nuak1 Decreases Tau and Reverses Phenotypes in a Tauopathy Mouse Model
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    sciencedirect.com/science/article/pii/S0896627316305815
  70. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Physiologically relevant factors influence tau phosphorylation by leucine‐rich repeat kinase 2
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    onlinelibrary.wiley.com/doi/10.1002/jnr.23614/full