41 Matching Annotations
  1. Last 7 days
  2. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    Oxidized MIF is an Alzheimer’s disease drug target relaying external risk factors to tau pathology
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    sciencedirect.com:5037/science/article/pii/S2666379125005932
  3. Jun 2025
  4. www.cell.com www.cell.com
    Computational and functional prioritization identifies genes that rescue behavior and reduce tau protein in fly and human cell models of Alzheimer disease
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    cell.com/ajhg/abstract/S0002-9297(25)00111-9
  5. 52.53.155.43 52.53.155.43
    PDF-html.html
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    52.53.155.43/919062f2a268aa52112faee2995da7ba1fbb82bd/PDF-html.html
  6. May 2025
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    hiPSC-neurons recapitulate the subtype-specific cell intrinsic nature of susceptibility to neurodegenerative disease-relevant aggregation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12087151/
  8. www.sciencedirect.com www.sciencedirect.com
    Differential roles of human tau isoforms in the modulation of inflammation and development of neuropathology
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    sciencedirect.com/science/article/pii/S0969996125001585
  9. Apr 2025
  10. www.sciencedirect.com www.sciencedirect.com
    Human MAPT knockin mouse models of frontotemporal dementia for the neurodegenerative research community
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    sciencedirect.com/science/article/pii/S2667237525000608
  11. Mar 2025
  12. link.springer.com link.springer.com
    Biochemical characterization of Tau protein changes and amyloid dynamics in a novel non-transgenic rat model of tauopathy
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    link.springer.com/article/10.1007/s00702-025-02909-z
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    High resolution autoradiography of [18F]MK-6240 and [18F]Flortaucipir shows similar neurofibrillary tangle binding patterns preferentially recognizing middling neurofibrillary tangle maturity
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    pmc.ncbi.nlm.nih.gov/articles/PMC11909026/
  14. Aug 2024
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tau‐mediated synaptic dysfunction is coupled with HCN channelopathy
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    ncbi.nlm.nih.gov/pmc/articles/PMC11350046/
  16. Feb 2024
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Nigrostriatal tau pathology in parkinsonism and Parkinson’s disease
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    ncbi.nlm.nih.gov/pmc/articles/PMC10834249/
  18. Oct 2023
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Behavioral and neuropathological characterization over the adult lifespan of the human tau knock-in mouse
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    ncbi.nlm.nih.gov/pmc/articles/PMC10576558/
  20. Dec 2022
  21. link.springer.com link.springer.com
    Cognitively impaired aged Octodon degus recapitulate major neuropathological features of sporadic Alzheimer’s disease
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    link.springer.com/article/10.1186/s40478-022-01481-x
  22. Nov 2022
  23. www.jneurosci.org www.jneurosci.org
    Integrity of neuronal size in the entorhinal cortex is a biologic substrate of exceptional cognitive aging
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    jneurosci.org/content/42/45/8587
  24. Jul 2022
  25. link.springer.com link.springer.com
    Anesthesia promotes acute expression of genes related to Alzheimer’s disease and latent tau aggregation in transgenic mouse models of tauopathy
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    link.springer.com/article/10.1186/s10020-022-00506-4
  26. Jun 2022
  27. link.springer.com link.springer.com
    Evidence of traumatic brain injury in headbutting bovids
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    link.springer.com/article/10.1007/s00401-022-02427-2
  28. www.sciencedirect.com www.sciencedirect.com
    Recapitulation of endogenous 4R tau expression and formation of insoluble tau in directly reprogrammed human neurons
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    sciencedirect.com/science/article/pii/S1934590922002004
  29. May 2022
  30. link.springer.com link.springer.com
    Alzheimer risk gene product Pyk2 suppresses tau phosphorylation and phenotypic effects of tauopathy
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    link.springer.com/article/10.1186/s13024-022-00526-y
  31. Apr 2022
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Reduction of Nuak1 decreases tau and reverses phenotypes in a tauopathy mouse model
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    ncbi.nlm.nih.gov/pmc/articles/PMC5745060/
  33. Mar 2022
  34. www.sciencedirect.com www.sciencedirect.com
    Homotypic fibrillization of TMEM106B across diverse neurodegenerative diseases
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    sciencedirect.com/science/article/pii/S0092867422002598
  35. Jan 2022
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Molecular Investigation of the Unfolded Protein Response in Select Human Tauopathies
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    ncbi.nlm.nih.gov/pmc/articles/PMC8764631/
  37. www.sciencedirect.com www.sciencedirect.com
    Uncovering specificity of endogenous TAU aggregation in a human iPSC-neuron TAU seeding model
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    sciencedirect.com/science/article/pii/S258900422101628X
  38. Aug 2021
  39. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Untitled document
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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.14593
  40. May 2021
  41. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Pathogenic MAPT mutations Q336H and Q336R have isoform‐dependent differences in aggregation propensity and microtubule dysfunction
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15358
  42. Mar 2021
  43. www.sciencedirect.com www.sciencedirect.com
    The AD tau core spontaneously self-assembles and recruits full-length tau to filaments
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    sciencedirect.com/science/article/pii/S2211124721001571
  44. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Suppression of tau‐induced phenotypes by vitamin E demonstrates the dissociation of oxidative stress and phosphorylation in mechanisms of tau toxicity
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15253
  45. Jan 2021
  46. www.sciencedirect.com www.sciencedirect.com
    Lowering Synaptogyrin-3 expression rescues Tau-induced memory defects and synaptic loss in the presence of microglial activation
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    sciencedirect.com/science/article/pii/S0896627320309983
  47. Dec 2020
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An in vitro bioengineered model of the human arterial neurovascular unit to study neurodegenerative diseases
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    ncbi.nlm.nih.gov/pmc/articles/PMC7678181/
  49. Sep 2020
  50. www.sciencedirect.com www.sciencedirect.com
    Posttranslational Modifications Mediate the Structural Diversity of Tauopathy Strains
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    sciencedirect.com/science/article/pii/S0092867420301082
  51. www.sciencedirect.com www.sciencedirect.com
    Management of Hsp90-Dependent Protein Folding by Small Molecules Targeting the Aha1 Co-Chaperone
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    sciencedirect.com/science/article/pii/S2451945620300337
  52. www.jneurosci.org www.jneurosci.org
    Nestin selectively facilitates the phosphorylation of the Lissencephaly-linked protein doublecortin (DCX) by cdk5/p35 to regulate growth cone morphology and Sema3a sensitivity in developing neurons.
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    jneurosci.org/content/40/19/3720
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Zonisamide Ameliorates Cognitive Impairment by Inhibiting ER Stress in a Mouse Model of Type 2 Diabetes Mellitus
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    ncbi.nlm.nih.gov/pmc/articles/PMC7367218/
  54. Jan 2020
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Microglia changes associated to Alzheimer’s disease pathology in aged chimpanzees
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    ncbi.nlm.nih.gov/pmc/articles/PMC6283685/
  56. onlinelibrary.wiley.com onlinelibrary.wiley.com
    High specificity of widely used phospho‐tau antibodies validated using a quantitative whole‐cell based assay
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    onlinelibrary.wiley.com/doi/10.1111/jnc.14830
  57. onlinelibrary.wiley.com onlinelibrary.wiley.com
    β‐amyloid and Tau Pathology in the Aging Feline Brain
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    onlinelibrary.wiley.com/doi/abs/10.1002/cne.24741
  58. www.sciencedirect.com www.sciencedirect.com
    Amyloid-Beta (Aβ) Plaques Promote Seeding and Spreading of Alpha-Synuclein and Tau in a Mouse Model of Lewy Body Disorders with Aβ Pathology
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    sciencedirect.com/science/article/pii/S0896627319308839
  59. www.sciencedirect.com www.sciencedirect.com
    Cholesterol Metabolism Is a Druggable Axis that Independently Regulates Tau and Amyloid-β in iPSC-Derived Alzheimer’s Disease Neurons
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    sciencedirect.com/science/article/pii/S1934590918306039
  60. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Untitled document
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    onlinelibrary.wiley.com/doi/full/10.1002/cne.24484
  61. Nov 2018
  62. www.jneurosci.org www.jneurosci.org
    Pathological Tau Strains from Human Brains Recapitulate the Diversity of Tauopathies in Nontransgenic Mouse Brain
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    jneurosci.org/content/37/47/11406
  63. Nov 2017
  64. www.sciencedirect.com www.sciencedirect.com
    Reduction of Nuak1 Decreases Tau and Reverses Phenotypes in a Tauopathy Mouse Model
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    sciencedirect.com/science/article/pii/S0896627316305815
  65. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Physiologically relevant factors influence tau phosphorylation by leucine‐rich repeat kinase 2
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    onlinelibrary.wiley.com/doi/10.1002/jnr.23614/full