117 Matching Annotations
  1. Sep 2025
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    Sigma-1 receptor counteracts non-cell-autonomous poly-PR-induced astrocytic oxidative stress in C9orf72 ALS
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    sciencedirect.com/science/article/pii/S221323172500388X
  3. Jul 2025
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    Antibody-mediated TGF-β1 activation for the treatment of diseases caused by deleterious T cell activity
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    sciencedirect.com/science/article/pii/S2211124725008320
  5. Jun 2025
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    Cell autonomous microglia defects in a stem cell model of frontotemporal dementia tau
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    link.springer.com/article/10.1038/s41380-025-03073-2
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    Sigma-1R–Pom121 axis preserves nuclear transport and integrity in poly-PR-induced C9orf72 ALS
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    sciencedirect.com/science/article/pii/S0969996125002086
  8. May 2025
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Epigenetic Plasticity Drives Carcinogenesis and Multi-Therapy Resistance in Multiple Myeloma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12048002/
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    Integrative characterization of MYC RNA-binding function
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    sciencedirect.com/science/article/pii/S2666979X2500134X
  11. Apr 2025
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    ZBP1 senses spliceosome stress through Z-RNA:DNA hybrid recognition
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    sciencedirect.com/science/article/pii/S1097276525003077
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    RAF1 kinase contributes to autophagic lysosome reformation
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    sciencedirect.com/science/article/pii/S221112472500261X
  14. Mar 2025
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The STRIPAK complex is required for radial sorting and laminin receptor expression in Schwann cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12035956/
  16. Feb 2025
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Histone H4 acetylation differentially modulates proliferation in adult oligodendrocyte progenitors
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    pmc.ncbi.nlm.nih.gov/articles/PMC11318668/
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RNA helicase MOV10 suppresses fear memory and dendritic arborization and regulates microtubule dynamics in hippocampal neurons
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    pmc.ncbi.nlm.nih.gov/articles/PMC11803958/
  19. Jan 2025
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Plural molecular and cellular mechanisms of pore domain KCNQ2 encephalopathy
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    pmc.ncbi.nlm.nih.gov/articles/PMC11703504/
  21. Dec 2024
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    A pan-family screen of nuclear receptors in immunocytes reveals ligand-dependent inflammasome control
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    sciencedirect.com/science/article/pii/S1074761324004904
  23. Nov 2024
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TRPM2 and CaMKII Signaling Drives Excessive GABAergic Synaptic Inhibition Following Ischemia
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    pmc.ncbi.nlm.nih.gov/articles/PMC11079974/
  25. Sep 2024
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeted transcriptional upregulation of SENP1 by CRISPR activation enhances deSUMOylation pathways to elicit antinociception in the spinal nerve ligation model of neuropathic pain
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    ncbi.nlm.nih.gov/pmc/articles/PMC11389604/
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    Uncoupling the CRMP2-CaV2.2 interaction reduces pain-like behavior in a preclinical joint-pain model
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    sciencedirect.com/science/article/pii/S1526590024006205
  28. Aug 2024
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    The RNA-binding protein EIF4A3 promotes axon development by direct control of the cytoskeleton
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    sciencedirect.com/science/article/pii/S2211124724010179
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The tyrosine phosphatases LAR and PTPRδ act as receptors of the nidogen-tetanus toxin complex
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    ncbi.nlm.nih.gov/pmc/articles/PMC11329502/
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    Protocol for analyzing TRAIL- and Fas-induced signaling complexes by immunoprecipitation from human cells
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    sciencedirect.com/science/article/pii/S2666166724002910
  32. Jul 2024
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    Very long-chain fatty acids control peroxisome dynamics via a feedback loop in intestinal stem cells during gut regeneration
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    sciencedirect.com/science/article/pii/S1534580724003988
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    PTEN acts as a crucial inflammatory checkpoint controlling TLR9/IL-6 axis in B cells
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    sciencedirect.com/science/article/pii/S2589004224016134
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    Arrestin-3-assisted activation of JNK3 mediates dopaminergic behavioral sensitization
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  36. 52.53.155.43 52.53.155.43
    PPAR_Interaction_with_UBR5_ATMIN_Promot-html.html
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    Proteomic analysis reveals a PLK1-dependent G2/M degradation program and a role for AKAP2 in coordinating the mitotic cytoskeleton
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    sciencedirect.com/science/article/pii/S2211124724008398
  38. www.embopress.org www.embopress.org
    The tyrosine phosphatases LAR and PTPRδ act as receptors of the nidogen-tetanus toxin complex
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    embopress.org/doi/10.1038/s44318-024-00164-8
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Uncoupling the CRMP2-CaV2.2 interaction reduces pain-like behavior in a preclinical osteoarthritis model
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    ncbi.nlm.nih.gov/pmc/articles/PMC11185632/
  40. Jun 2024
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cell autonomous microglia defects in a stem cell model of frontotemporal dementia
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    ncbi.nlm.nih.gov/pmc/articles/PMC11118656/
  42. May 2024
  43. elifesciences.org elifesciences.org
    Ribosome subunit attrition and activation of the p53–MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition
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    elifesciences.org/articles/90683
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    N4BP1 coordinates ubiquitin-dependent crosstalk within the IκB kinase family to limit Toll-like receptor signaling and inflammation
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    sciencedirect.com/science/article/pii/S1074761324002097
  45. Apr 2024
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    O-GlcNAcylation of RBM14 contributes to elevated cellular O-GlcNAc through regulation of OGA protein stability
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    sciencedirect.com/science/article/pii/S2211124724004911
  47. Mar 2024
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    RPGR is a guanine nucleotide exchange factor for the small GTPase RAB37 required for retinal function via autophagy regulation
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    sciencedirect.com/science/article/pii/S2211124724003383
  49. Feb 2024
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    ABHD7-mediated depalmitoylation of lamin A promotes myoblast differentiation
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  51. Dec 2023
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    SYK ubiquitination by CBL E3 ligases restrains cross-presentation of dead cell-associated antigens by type 1 dendritic cells
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    sciencedirect.com/science/article/pii/S2211124723015188
  53. Oct 2023
  54. www.science.org www.science.org
    Lymph node–resident dendritic cells drive TH2 cell development involving MARCH1
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    science.org/doi/10.1126/sciimmunol.abh0707
  55. Sep 2023
  56. www.nature.com www.nature.com
    Long non-coding RNA SNHG8 drives stress granule formation in tauopathies
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    nature.com/articles/s41380-023-02237-2
  57. www.sciencedirect.com www.sciencedirect.com
    Oligodendrocyte precursor cells stop sensory axons regenerating into the spinal cord
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    sciencedirect.com/science/article/pii/S2211124723010793
  58. Aug 2023
  59. www.biorxiv.org www.biorxiv.org
    Acylation of MLKL impacts its function in necroptosis
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    biorxiv.org/content/10.1101/2023.08.19.553906v1
  60. Jul 2023
  61. www.sciencedirect.com www.sciencedirect.com
    Type 2 diabetes susceptibility gene GRK5 regulates physiological pancreatic β-cell proliferation via phosphorylation of HDAC5
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    sciencedirect.com/science/article/pii/S2589004223013883
  62. Jun 2023
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Detection of Arc/Arg3.1 oligomers in rat brain: constitutive and synaptic activity-evoked dimer expression in vivo
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    ncbi.nlm.nih.gov/pmc/articles/PMC10289200/
  64. www.sciencedirect.com www.sciencedirect.com
    Acetylation halts missense mutant p53 aggregation and rescues tumor suppression in non-small cell lung cancers
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    sciencedirect.com/science/article/pii/S2589004223010805
  65. May 2023
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    BUB-1-bound PLK-1 directs CDC-20 kinetochore recruitment to ensure timely embryonic mitoses
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    sciencedirect.com/science/article/pii/S0960982223004694
  67. Apr 2023
  68. link.springer.com link.springer.com
    Defects in lysosomal function and lipid metabolism in human microglia harboring a TREM2 loss of function mutation
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    link.springer.com/article/10.1007/s00401-023-02568-y
  69. Mar 2023
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NLRC5 affects diet-induced adiposity in female mice and co-regulates peroxisome proliferator-activated receptor PPARγ target genes
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    ncbi.nlm.nih.gov/pmc/articles/PMC10034470/
  71. Feb 2023
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The SARS-CoV-2 accessory protein Orf3a is not an ion channel, but does interact with trafficking proteins
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    ncbi.nlm.nih.gov/pmc/articles/PMC9910834/
  73. Jan 2023
  74. www.sciencedirect.com www.sciencedirect.com
    Targeting KRAS-mutant stomach/colorectal tumors by disrupting the ERK2-p53 complex
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    sciencedirect.com/science/article/pii/S2211124722018769
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    Use of metabolic glycoengineering and pharmacological inhibitors to assess lipid and protein sialylation on cells
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15737
  76. Nov 2022
  77. www.sciencedirect.com www.sciencedirect.com
    Dynamic quality control machinery that operates across compartmental borders mediates the degradation of mammalian nuclear membrane proteins
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    sciencedirect.com/science/article/pii/S2211124722015492
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    Transcription factors TEAD2 and E2A globally repress acetyl-CoA synthesis to promote tumorigenesis
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  79. May 2022
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    NSD1 mediates antagonism between SWI/SNF and polycomb complexes and is required for transcriptional activation upon EZH2 inhibition
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    The Mettl3 epitranscriptomic writer amplifies p53 stress responses
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  82. Apr 2022
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The non-adrenergic imidazoline-1 receptor protein Nischarin is a key regulator of astrocyte glutamate uptake
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    ncbi.nlm.nih.gov/pmc/articles/PMC9010640/
  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ACTL6a coordinates axonal caliber recognition and myelination in the peripheral nerve.
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    ncbi.nlm.nih.gov/pmc/articles/PMC9010646/
  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lymph node–resident dendritic cells drive TH2 cell development involving MARCH1
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    ncbi.nlm.nih.gov/pmc/articles/PMC8736284/
  86. www.sciencedirect.com www.sciencedirect.com
    Deadenylase-dependent mRNA decay of GDF15 and FGF21 orchestrates food intake and energy expenditure
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    sciencedirect.com/science/article/pii/S1550413122000936
  87. Mar 2022
  88. link.springer.com link.springer.com
    Development and Validation of Arc Nanobodies: New Tools for Probing Arc Dynamics and Function
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    link.springer.com/article/10.1007/s11064-022-03573-5
  89. Feb 2022
  90. www.sciencedirect.com www.sciencedirect.com
    Co-adaptor driven assembly of a CUL3 E3 ligase complex
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  91. Dec 2021
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    Kel1 is a phosphorylation-regulated noise suppressor of the pheromone signaling pathway
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  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FMRP and MOV10 regulate Dicer1 expression and dendrite development
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    ncbi.nlm.nih.gov/pmc/articles/PMC8631628/
  94. Oct 2021
  95. www.embopress.org www.embopress.org
    Promyelocytic leukemia protein targets MK2 to promote cytotoxicity
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    embopress.org/doi/full/10.15252/embr.202052254
  96. Sep 2021
  97. www.sciencedirect.com www.sciencedirect.com
    Preparation of monovalent follistatin-like 3-Fc-fusion protein and evaluation of its effects on muscle mass in mice
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    sciencedirect.com/science/article/pii/S2666166721005451
  98. Aug 2021
  99. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TRAF6 function as a novel co-regulator of Wnt3a target genes in prostate cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC6642315/
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    Untitled document
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    Sex-specific regulation of spine density and synaptic proteins by G-protein-coupled estrogen receptor (GPER)1 in developing hippocampus
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    sciencedirect.com/science/article/pii/S0306452221003894
  102. elifesciences.org elifesciences.org
    The novel SH3 domain protein Dlish/CG10933 mediates fat signaling in Drosophila by binding and regulating Dachs
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    elifesciences.org/content/5/e16624
  103. Jul 2021
  104. elifesciences.org elifesciences.org
    The novel SH3 domain protein Dlish/CG10933 mediates fat signaling in Drosophila by binding and regulating Dachs
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    elifesciences.org/content/5/e16624
  105. www.sciencedirect.com www.sciencedirect.com
    Site-specific O-GlcNAcylation of Psme3 maintains mouse stem cell pluripotency by impairing P-body homeostasis
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    sciencedirect.com/science/article/pii/S2211124721007592
  106. Jun 2021
  107. cancerres.aacrjournals.org cancerres.aacrjournals.org
    STIM1 Mediates Calcium-dependent Epigenetic Reprogramming in Pancreatic Cancer
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    cancerres.aacrjournals.org/content/81/11/2943
  108. link.springer.com link.springer.com
    A Novel Methodology Using Dexamethasone to Induce Neuronal Differentiation in the CNS-Derived Catecholaminergic CAD Cells
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    link.springer.com/article/10.1007/s10571-021-01109-z
  109. May 2021
  110. www.sciencedirect.com www.sciencedirect.com
    Viral infection of the ovaries compromises pregnancy and reveals innate immune mechanisms protecting fertility
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    Systemic administration of monovalent follistatin-like 3-Fc-fusion protein increases muscle mass in mice
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    sciencedirect.com/science/article/pii/S2589004221004569
  112. www.sciencedirect.com www.sciencedirect.com
    Tandem Deubiquitination and Acetylation of SPRTN Promotes DNA-Protein Crosslink Repair and Protects against Aging
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    sciencedirect.com/science/article/pii/S1097276520304299
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    A class of viral inducer of degradation of the necroptosis adaptor RIPK3 regulates virus-induced inflammation
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    Developmentally Programmed Tankyrase Activity Upregulates β-Catenin and Licenses Progression of Embryonic Genome Activation
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    sciencedirect.com/science/article/pii/S1534580720303506
  115. Apr 2021
  116. www.sciencedirect.com www.sciencedirect.com
    Diversity of the Gβγ complexes defines spatial and temporal bias of GPCR signaling
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    sciencedirect.com/science/article/pii/S2405471221000405
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    TBL1XR1 Mutations Drive Extranodal Lymphoma by Inducing a Pro-tumorigenic Memory Fate
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    sciencedirect.com/science/article/pii/S0092867420306826
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    Protein acylation by saturated very long chain fatty acids and endocytosis are involved in necroptosis
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    sciencedirect.com/science/article/pii/S2451945621001513
  119. Mar 2021
  120. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    The tumor suppressor LATS2 reduces v‐Src‐induced membrane blebs in a kinase activity‐independent manner
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202001909R
  121. Feb 2021
  122. www.cell.com www.cell.com
    A Global Map of G Protein Signaling Regulation by RGS Proteins
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    cell.com/cell/fulltext/S0092-8674(20)31140-5
  123. www.sciencedirect.com www.sciencedirect.com
    ARHGEF3 regulates skeletal muscle regeneration and strength through autophagy
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    sciencedirect.com/science/article/pii/S2211124721000449
  124. Jan 2021
  125. www.sciencedirect.com www.sciencedirect.com
    Impact of WIN site inhibitor on the WDR5 interactome
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    sciencedirect.com/science/article/pii/S2211124720316259
  126. Dec 2020
  127. www.mdpi.com www.mdpi.com
    UBE1a Suppresses Herpes Simplex Virus-1 Replication
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    mdpi.com/1999-4915/12/12/1391
  128. Oct 2020
  129. www.sciencedirect.com www.sciencedirect.com
    MED19 Regulates Adipogenesis and Maintenance of White Adipose Tissue Mass by Mediating PPARγ-Dependent Gene Expression
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    sciencedirect.com/science/article/pii/S2211124720312171
  130. Sep 2020
  131. www.sciencedirect.com www.sciencedirect.com
    Site-Specific Photo-Crosslinking Proteomics Reveal Regulation of IFITM3 Trafficking and Turnover by VCP/p97 ATPase
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    sciencedirect.com/science/article/pii/S2451945620300787
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    An Essential and Cell-Cycle-Dependent ORC Dimerization Cycle Regulates Eukaryotic Chromosomal DNA Replication
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