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Jun 2025
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Sigma-1R–Pom121 axis preserves nuclear transport and integrity in poly-PR-induced C9orf72 ALS

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May 2025
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Integrative characterization of MYC RNA-binding function

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Apr 2025
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Dietary oleic acid drives obesogenic adipogenesis via modulation of LXRα signaling

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RAF1 kinase contributes to autophagic lysosome reformation

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BCL-XL Protects ASS1-Deficient Cancers from Arginine Starvation–Induced Apoptosis

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pmc.ncbi.nlm.nih.gov/articles/PMC11964295/
Mar 2025
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The domesticated transposon protein L1TD1 associates with its ancestor L1 ORF1p to promote LINE-1 retrotransposition

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Feb 2025
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Histone H4 acetylation differentially modulates proliferation in adult oligodendrocyte progenitors

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PDF-html.html

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Jan 2025
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Nutrient-sensing alteration leads to age-associated distortion of intestinal stem cell differentiating direction

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Plural molecular and cellular mechanisms of pore domain KCNQ2 encephalopathy

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pmc.ncbi.nlm.nih.gov/articles/PMC11703504/
Dec 2024
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TTF2 promotes replisome eviction from stalled forks in mitosis

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Nov 2024
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STK19 positions TFIIH for cell-free transcription-coupled DNA repair

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Sep 2024
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Targeted transcriptional upregulation of SENP1 by CRISPR activation enhances deSUMOylation pathways to elicit antinociception in the spinal nerve ligation model of neuropathic pain

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  DOI: 10.1097/j.pain.0000000000003080
  
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Uncoupling the CRMP2-CaV2.2 interaction reduces pain-like behavior in a preclinical joint-pain model

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Aug 2024
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The RNA-binding protein EIF4A3 promotes axon development by direct control of the cytoskeleton

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The tyrosine phosphatases LAR and PTPRδ act as receptors of the nidogen-tetanus toxin complex

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Functional characterization of the SDR42E1 reveals its role in vitamin D biosynthesis

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  DOI: 10.1016/j.heliyon.2024.e36466
  
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Protocol for analyzing TRAIL- and Fas-induced signaling complexes by immunoprecipitation from human cells

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Jul 2024
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Very long-chain fatty acids control peroxisome dynamics via a feedback loop in intestinal stem cells during gut regeneration

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Arrestin-3-assisted activation of JNK3 mediates dopaminergic behavioral sensitization

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PPAR_Interaction_with_UBR5_ATMIN_Promot-html.html

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The tyrosine phosphatases LAR and PTPRδ act as receptors of the nidogen-tetanus toxin complex

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Uncoupling the CRMP2-CaV2.2 interaction reduces pain-like behavior in a preclinical osteoarthritis model

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Jun 2024
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SAFB regulates hippocampal stem cell fate by targeting Drosha to destabilize Nfib mRNA

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May 2024
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N4BP1 coordinates ubiquitin-dependent crosstalk within the IκB kinase family to limit Toll-like receptor signaling and inflammation

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Apr 2024
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Rab7-dependent regulation of goblet cell protein CLCA1 modulates gastrointestinal homeostasis

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Galectin-1 mediates chronic STING activation in tumors to promote metastasis through MDSC recruitment

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  DOI: 10.1158/0008-5472.CAN-23-0046
  
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Mar 2024
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RPGR is a guanine nucleotide exchange factor for the small GTPase RAB37 required for retinal function via autophagy regulation

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Feb 2024
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ABHD7-mediated depalmitoylation of lamin A promotes myoblast differentiation

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Jan 2024
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In silico protein interaction screening uncovers DONSON’s role in replication initiation

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Dec 2023
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SYK ubiquitination by CBL E3 ligases restrains cross-presentation of dead cell-associated antigens by type 1 dendritic cells

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Sep 2023
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Adipocyte glucocorticoid receptor inhibits immune regulatory genes to maintain immune cell homeostasis in adipose tissue

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  DOI: 10.1210/endocr/bqad143
  
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Estradiol and 3β-diol protect female cortical astrocytes by regulating connexin 43 Gap Junctions

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  DOI: 10.1016/j.mce.2023.112045
  
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Aug 2023
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In silico protein interaction screening uncovers DONSON’s role in replication initiation

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science.org/doi/10.1126/science.adi3448
Jun 2023
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Detection of Arc/Arg3.1 oligomers in rat brain: constitutive and synaptic activity-evoked dimer expression in vivo

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Acetylation halts missense mutant p53 aggregation and rescues tumor suppression in non-small cell lung cancers

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Novel MKRN3 Missense Mutations Associated with Central Precocious Puberty Reveal Distinct Effects on Ubiquitination

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(R)-2-hydroxyglutarate inhibits KDM5 histone lysine demethylases to drive transformation in IDH-mutant cancers

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ESCRT recruitment to SARS-CoV-2 spike induces virus-like particles that improve mRNA vaccines

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Glioma epileptiform activity and progression are driven by IGSF3-mediated potassium dysregulation

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Two Hippo signaling modules orchestrate liver size and tumorigenesis

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CHD1 promotes sensitivity to Aurora kinase inhibitors by suppressing interaction of AURKA with its coactivator TPX2

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BPS Publications

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TRIM21-dependent target protein ubiquitination mediates cell-free Trim-Away

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SSRN-id4254517-html.html

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Dynamic quality control machinery that operates across compartmental borders mediates the degradation of mammalian nuclear membrane proteins

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Transcription factors TEAD2 and E2A globally repress acetyl-CoA synthesis to promote tumorigenesis

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Transmembrane protein KIRREL1 regulates Hippo signaling via a feedback loop and represents a therapeutic target in YAP/TAZ-active cancers

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can-22-0631-html.html

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Differential regulation of alternate promoter regions in Sox17 during endodermal and vascular endothelial development

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NSD1 mediates antagonism between SWI/SNF and polycomb complexes and is required for transcriptional activation upon EZH2 inhibition

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The Mettl3 epitranscriptomic writer amplifies p53 stress responses

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WWC proteins mediate LATS1/2 activation by Hippo kinases and imply a tumor suppression strategy

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ACTL6a coordinates axonal caliber recognition and myelination in the peripheral nerve.

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Deadenylase-dependent mRNA decay of GDF15 and FGF21 orchestrates food intake and energy expenditure

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Development and Validation of Arc Nanobodies: New Tools for Probing Arc Dynamics and Function

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Lipid flippase dysfunction as a therapeutic target for endosomal anomalies in Alzheimer’s disease

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Calpain-2 regulates hypoxia/HIF-induced plasticity toward amoeboid cancer cell migration and metastasis

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Topoisomerase 1 activity during mitotic transcription favors the transition from mitosis to G1

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Cardiac proteomics reveals sex chromosome-dependent differences between males and females that arise prior to gonad formation

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Promyelocytic leukemia protein targets MK2 to promote cytotoxicity

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Dynamic interplay of two molecular switches enabled by the MEK1/2-ERK1/2 and IL-6-STAT3 signaling axes controls epithelial cell migration in response to growth factors

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TRAF6 function as a novel co-regulator of Wnt3a target genes in prostate cancer

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Untitled document

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Untitled document

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Thyroid Hormone Receptor β Suppression of RUNX2 is Mediated by Brahma Related Gene 1 Dependent Chromatin Remodeling

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ARv7 Represses Tumor-Suppressor Genes in Castration-Resistant Prostate Cancer

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Site-specific O-GlcNAcylation of Psme3 maintains mouse stem cell pluripotency by impairing P-body homeostasis

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STIM1 Mediates Calcium-dependent Epigenetic Reprogramming in Pancreatic Cancer

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Unique Immune Cell Coactivators Specify Locus Control Region Function and Cell Stage

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Tandem Deubiquitination and Acetylation of SPRTN Promotes DNA-Protein Crosslink Repair and Protects against Aging

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A class of viral inducer of degradation of the necroptosis adaptor RIPK3 regulates virus-induced inflammation

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Diversity of the Gβγ complexes defines spatial and temporal bias of GPCR signaling

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TBL1XR1 Mutations Drive Extranodal Lymphoma by Inducing a Pro-tumorigenic Memory Fate

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SETD5-Coordinated Chromatin Reprogramming Regulates Adaptive Resistance to Targeted Pancreatic Cancer Therapy

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PRMT6 methylation of RCC1 regulates mitosis, tumorigenicity, and radiation response of glioblastoma stem cells

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Pimavanserin, a 5HT2A receptor inverse agonist, rapidly suppresses Aβ production and related pathology in a mouse model of Alzheimer’s disease

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The tumor suppressor LATS2 reduces v‐Src‐induced membrane blebs in a kinase activity‐independent manner

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Protein Synthesis in the Developing Neocortex at Near-Atomic Resolution Reveals Ebp1-Mediated Neuronal Proteostasis at the 60S Tunnel Exit

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A Global Map of G Protein Signaling Regulation by RGS Proteins

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Metabolic compensation activates pro-survival mTORC1 signaling upon 3-phosphoglycerate dehydrogenase inhibition in osteosarcoma

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MYC regulates ribosome biogenesis and mitochondrial gene expression programs through its interaction with host cell factor–1

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Slc26a6 is an apical membrane anion exchanger that drives HCO3−-dependent fluid secretion in murine pancreatic acinar cells

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MED19 Regulates Adipogenesis and Maintenance of White Adipose Tissue Mass by Mediating PPARγ-Dependent Gene Expression

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An Essential and Cell-Cycle-Dependent ORC Dimerization Cycle Regulates Eukaryotic Chromosomal DNA Replication

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Internalization of trophoblastic small extracellular vesicles and detection of their miRNA cargo in P-bodies

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p53 Integrates Temporal WDR5 Inputs during Neuroectoderm and Mesoderm Differentiation of Mouse Embryonic Stem Cells

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GATA2 and progesterone receptor interaction in endometrial stromal cells undergoing decidualization

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Revisiting CB1 cannabinoid receptor detection and the exploration of its interacting partners

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FMRP Control of Ribosome Translocation Promotes Chromatin Modifications and Alternative Splicing of Neuronal Genes Linked to Autism

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Quality Control of ER Membrane Proteins by the RNF185/Membralin Ubiquitin Ligase Complex

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Site-Specific Photo-Crosslinking Proteomics Reveal Regulation of IFITM3 Trafficking and Turnover by VCP/p97 ATPase

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Slc26a6 is an apical membrane anion exchanger that drives HCO3−-dependent fluid secretion in murine pancreatic acinar cells | American Journal of Physiology-Cell Physiology

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Indirect monitoring of TORC1 signalling pathway reveals molecular diversity among different yeast strains

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CRISPR/Cas9 Screens Reveal Multiple Layers of B cell CD40 Regulation

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KAE1 Allelic Variants Affect TORC1 Activation and Fermentation Kinetics in Saccharomyces cerevisiae

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TRAF6 function as a novel co-regulator of Wnt3a target genes in prostate cancer

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Untitled document

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Untitled document

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  DOI: 10.1016/j.stem.2019.02.017
  
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FOXM1 Deubiquitination by USP21 Regulates Cell Cycle Progression and Paclitaxel Sensitivity in Basal-like Breast Cancer

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WDR5 Stabilizes Actin Architecture to Promote Multiciliated Cell Formation

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Hsp90 Mediates Membrane Deformation and Exosome Release

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The THO Complex Coordinates Transcripts for Synapse Development and Dopamine Neuron Survival

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Urea Cycle Dysregulation Generates Clinically Relevant Genomic and Biochemical Signatures

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DUB3 Promotes BET Inhibitor Resistance and Cancer Progression by Deubiquitinating BRD4

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TALE factors use two distinct functional modes to control an essential zebrafish gene expression program

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ER Lipid Defects in Neuropeptidergic Neurons Impair Sleep Patterns in Parkinson’s Disease

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Mutant p53 Gains Its Function via c-Myc Activation upon CDK4 Phosphorylation at Serine 249 and Consequent PIN1 Binding

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RAPGEF5 Regulates Nuclear Translocation of β-Catenin

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MST4 Phosphorylation of ATG4B Regulates Autophagic Activity, Tumorigenicity, and Radioresistance in Glioblastoma

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p27Kip1 promotes invadopodia turnover and invasion through the regulation of the PAK1/Cortactin pathway

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Caspase-8 Acts in a Non-enzymatic Role as a Scaffold for Assembly of a Pro-inflammatory “FADDosome” Complex upon TRAIL Stimulation

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