158 Matching Annotations
  1. Apr 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Molecular basis for pH sensing in the KDEL trafficking receptor
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    1. scibot 16 Apr 2024
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      DOI: 10.1016/j.str.2024.03.013

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    sciencedirect.com/science/article/pii/S0969212624000959
  3. www.nature.com www.nature.com
    Genetic and pharmacological reduction of CDK14 mitigates synucleinopathy
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    1. scibot 05 Apr 2024
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      DOI: 10.1038/s41419-024-06534-8

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    nature.com/articles/s41419-024-06534-8
  4. Mar 2024
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TEAD1 is crucial for developmental myelination, Remak bundles, and functional regeneration of peripheral nerves
    1
    1. scibot 27 Mar 2024
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      DOI: 10.7554/eLife.87394

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    ncbi.nlm.nih.gov/pmc/articles/PMC10959528/
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Drug-resistant EGFR mutations promote lung cancer by stabilizing interfaces in ligand-free kinase-active EGFR oligomers
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    1. scibot 22 Mar 2024
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      DOI: 10.1038/s41467-024-46284-x

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    ncbi.nlm.nih.gov/pmc/articles/PMC10951324/
  7. Feb 2024
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    Redistribution of the glycocalyx exposes phagocytic determinants on apoptotic cells
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    1. scibot 15 Feb 2024
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      DOI: 10.1016/j.devcel.2024.01.020

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    2. scibot 15 Feb 2024
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      DOI: 10.1016/j.devcel.2024.01.020

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    sciencedirect.com/science/article/pii/S1534580724000406
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    Leishmania profilin interacts with actin through an unusual structural mechanism to control cytoskeletal dynamics in parasites
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    1. scibot 13 Feb 2024
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      DOI: 10.1016/j.jbc.2024.105740

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    2. scibot 13 Feb 2024
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      DOI: 10.1016/j.jbc.2024.105740

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    sciencedirect.com/science/article/pii/S0021925824001169
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    Schwann cell promotes macrophage recruitment through IL-17B/IL-17RB pathway in injured peripheral nerves
    1
    1. scibot 13 Feb 2024
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      DOI: 10.1016/j.celrep.2024.113753

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    sciencedirect.com/science/article/pii/S2211124724000810
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    Protocol for detection of in vitro R-loop formation using dot blots
    1
    1. scibot 02 Feb 2024
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      DOI: 10.1016/j.xpro.2024.102857

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    sciencedirect.com/science/article/pii/S2666166724000224
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    Gut-liver axis calibrates intestinal stem cell fitness
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    1. scibot 02 Feb 2024
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      DOI: 10.1016/j.cell.2024.01.001

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    sciencedirect.com/science/article/pii/S0092867424000035
  13. Jan 2024
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SARS-CoV-2 NSP14 MTase activity is critical for inducing canonical NF-κB activation
    1
    1. scibot 12 Jan 2024
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      DOI: 10.1042/BSR20231418

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    ncbi.nlm.nih.gov/pmc/articles/PMC10776897/
  15. Dec 2023
  16. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Proteomics analysis of the brain from a Gaucher disease mouse identifies pathological pathways including a possible role for transglutaminase 1
    1
    1. scibot 16 Dec 2023
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      DOI: 10.1111/jnc.16024

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    onlinelibrary.wiley.com/doi/10.1111/jnc.16024
  17. Nov 2023
  18. www.sciencedirect.com www.sciencedirect.com
    Entorhinohippocampal cholecystokinin modulates spatial learning by facilitating neuroplasticity of hippocampal CA3-CA1 synapses
    1
    1. scibot 28 Nov 2023
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      DOI: 10.1016/j.celrep.2023.113467

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    sciencedirect.com/science/article/pii/S2211124723014791
  19. www.sciencedirect.com www.sciencedirect.com
    p57Kip2 acts as a transcriptional corepressor to regulate intestinal stem cell fate and proliferation
    1
    1. scibot 10 Nov 2023
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      DOI: 10.1016/j.celrep.2023.112659

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    sciencedirect.com/science/article/pii/S2211124723006708
  20. Oct 2023
  21. 52.53.155.43 52.53.155.43
    The T766M-EGFR lung cancer mutation promotes tumor growth by exploiting newfound assembly mechanisms in ligand-free EGFR oligomers
    1
    1. scibot 14 Oct 2023
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      DOI: 10.1101/2023.06.16.545259

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    52.53.155.43/e45e39aa6be90d4518c1365e2458466145a6420b/2023.06.16.545259v2.full-html.html
  22. www.biorxiv.org www.biorxiv.org
    A gut meta-interactome map reveals modulation of human immunity by microbiome effectors
    1
    1. scibot 06 Oct 2023
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      DOI: 10.1101/2023.09.25.559292

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    biorxiv.org/content/10.1101/2023.09.25.559292v1
  23. Sep 2023
  24. www.sciencedirect.com www.sciencedirect.com
    Pannexin-1 opening in neuronal edema causes cell death but also leads to protection via increased microglia contacts
    1
    1. scibot 30 Sep 2023
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      DOI: 10.1016/j.celrep.2023.113128

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    sciencedirect.com/science/article/pii/S2211124723011403
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    Astrocyte lipocalin-2 modestly effects disease severity in a mouse model of multiple sclerosis while reducing mature oligodendrocyte protein and mRNA expression
    1
    1. scibot 30 Sep 2023
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      DOI: 10.1016/j.neulet.2023.137497

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    sciencedirect.com/science/article/pii/S0304394023004561
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    MATR3 is an endogenous inhibitor of DUX4 in FSHD muscular dystrophy
    1
    1. scibot 14 Sep 2023
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      DOI: 10.1016/j.celrep.2023.113120

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    sciencedirect.com/science/article/pii/S2211124723011324
  27. www.sciencedirect.com www.sciencedirect.com
    A co-opted endogenous retroviral envelope promotes cell survival by controlling CTR1-mediated copper transport and homeostasis
    1
    1. scibot 08 Sep 2023
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      DOI: 10.1016/j.celrep.2023.113065

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    sciencedirect.com/science/article/pii/S2211124723010768
  28. Aug 2023
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Analyzing the topology of N-linked glycans by PNGase F accessibility assay
    1
    1. scibot 12 Aug 2023
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      DOI: 10.1016/j.xpro.2023.102458

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    ncbi.nlm.nih.gov/pmc/articles/PMC10407232/
  30. Jul 2023
  31. www.sciencedirect.com www.sciencedirect.com
    MEF2A suppresses stress responses that trigger DDX41-dependent IFN production
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    1. scibot 21 Jul 2023
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      DOI: 10.1016/j.celrep.2023.112805

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    sciencedirect.com/science/article/pii/S2211124723008161
  32. www.sciencedirect.com www.sciencedirect.com
    Methionine oxidation selectively enhances T cell reactivity against a melanoma antigen
    1
    1. scibot 15 Jul 2023
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      DOI: 10.1016/j.isci.2023.107205

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    sciencedirect.com/science/article/pii/S2589004223012828
  33. Jun 2023
  34. www.sciencedirect.com www.sciencedirect.com
    BUB-1-bound PLK-1 directs CDC-20 kinetochore recruitment to ensure timely embryonic mitoses
    1
    1. scibot 03 Jun 2023
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      DOI: 10.1016/j.cub.2023.04.021

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    sciencedirect.com/science/article/pii/S0960982223004694
  35. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Endonuclease VIII-like 1 deficiency potentiates nigrostriatal dopaminergic neuron degeneration in a male mouse model of Parkinson's disease
    1
    1. scibot 01 Jun 2023
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      DOI: 10.1111/jnc.15794

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    onlinelibrary.wiley.com/doi/10.1111/jnc.15794
  36. May 2023
  37. www.sciencedirect.com www.sciencedirect.com
    Protocol to determine the subcellular localization of protein interactions in murine keratinocytes
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    1. scibot 18 May 2023
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      DOI: 10.1016/j.xpro.2023.102309

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    sciencedirect.com/science/article/pii/S2666166723002769
  38. www.sciencedirect.com www.sciencedirect.com
    ESCRT recruitment to SARS-CoV-2 spike induces virus-like particles that improve mRNA vaccines
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    1. scibot 06 May 2023
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      DOI: 10.1016/j.cell.2023.04.024

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    sciencedirect.com/science/article/pii/S0092867423004208
  39. www.sciencedirect.com www.sciencedirect.com
    A hypometabolic defense strategy against malaria
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    1. scibot 05 May 2023
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      DOI: 10.1016/j.cmet.2022.06.011

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    sciencedirect.com/science/article/pii/S1550413122002315
  40. Apr 2023
  41. www.sciencedirect.com www.sciencedirect.com
    Differential Hsp90-dependent gene expression is strain-specific and common among yeast strains
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    sciencedirect.com/science/article/pii/S2589004223007125
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    A tissue injury sensing and repair pathway distinct from host pathogen defense
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      DOI: 10.1016/j.cell.2023.03.031

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    sciencedirect.com/science/article/pii/S0092867423003288
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    Axonal mRNA binding of hnRNP A/B is crucial for axon targeting and maturation of olfactory sensory neurons
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      DOI: 10.1016/j.celrep.2023.112398

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    sciencedirect.com/science/article/pii/S2211124723004096
  44. www.biorxiv.org www.biorxiv.org
    Conformational dynamics of lipid transfer domains provide a general framework to decode their functional mechanism
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      DOI: 10.1101/2023.04.11.536463

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    biorxiv.org/content/10.1101/2023.04.11.536463v1
  45. www.sciencedirect.com www.sciencedirect.com
    Ultra-rare complement factor 8 coding variants in families with age-related macular degeneration
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      DOI: 10.1016/j.isci.2023.106417

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    sciencedirect.com/science/article/pii/S2589004223004947
  46. Mar 2023
  47. www.sciencedirect.com www.sciencedirect.com
    Topological regulation of a transmembrane protein by luminal-to-cytosolic retrotranslocation of glycosylated sequence
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      DOI: 10.1016/j.celrep.2023.112311

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    sciencedirect.com/science/article/pii/S2211124723003224
  48. Feb 2023
  49. elifesciences.org elifesciences.org
    A concerted mechanism involving ACAT and SREBPs by which oxysterols deplete accessible cholesterol to restrict microbial infection
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      DOI: 10.7554/eLife.83534

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    elifesciences.org/articles/83534
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TRAF6 controls T cell homeostasis by maintaining the equilibrium of MALT1 scaffolding and protease functions
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    1. scibot 11 Feb 2023
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      DOI: 10.3389/fimmu.2023.1111398

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    ncbi.nlm.nih.gov/pmc/articles/PMC9902345/
  51. Jan 2023
  52. www.sciencedirect.com www.sciencedirect.com
    Plakophilin 3 facilitates G1/S phase transition and enhances proliferation by capturing RB protein in the cytoplasm and promoting EGFR signaling
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      DOI: 10.1016/j.celrep.2023.112031

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    sciencedirect.com/science/article/pii/S2211124723000426
  53. academic.oup.com academic.oup.com
    ERRα attenuates vascular inflammation via enhanced NFκB degradation pathway
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    1. scibot 19 Jan 2023
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      DOI: 10.1210/endocr/bqac212

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    academic.oup.com/endo/article/164/3/bqac212/6936569
  54. link.springer.com link.springer.com
    Short photoperiod modulates behavior, cognition and hippocampal neurogenesis in male Japanese quail
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      DOI: 10.1038/s41598-023-28248-1

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    L- and T-type Ca2+ channels dichotomously contribute to... : Neural Regeneration Research
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    The SARS-CoV-2 spike S375F mutation characterizes the Omicron BA.1 variant
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    The Scaffolding Function of LSD1/KDM1A Reinforces a Negative Feedback Loop to Repress Stem Cell Gene Expression during Primitive Hematopoiesis
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  59. Dec 2022
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    Notch-dependent Abl signaling regulates cell motility during ommatidial rotation in Drosophila
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    Monitoring fusion kinetics of viral and target cell membranes in living cells using a SARS-CoV-2 spike protein-mediated membrane fusion assay
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    Crystal structure of the CDK11 kinase domain bound to the small-molecule inhibitor OTS964
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    Structure and mechanism of human cystine exporter cystinosin
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    Epigenetic remodeling by vitamin C potentiates plasma cell differentiation
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    Temporal control of PDGFRα regulates the fibroblast-to-myofibroblast transition in wound healing
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    Rhomboid protease RHBDL4 promotes retrotranslocation of aggregation-prone proteins for degradation
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  71. Jul 2022
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  73. Jun 2022
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    BAFFR activates PI3K/AKT signaling in human naive but not in switched memory B cells through direct interactions with B cell antigen receptors
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  75. May 2022
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    Differential Effects of APOE Genotype on MicroRNA Cargo of Cerebrospinal Fluid Extracellular Vesicles in Females With Alzheimer’s Disease Compared to Males
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    Efficacy and specificity of inhibitors of BCL-2 family protein interactions assessed by affinity measurements in live cells
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    MDGAs are fast-diffusing molecules that delay excitatory synapse development by altering neuroligin behavior
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    Mesothelial cell-derived antigen-presenting cancer-associated fibroblasts induce expansion of regulatory T cells in pancreatic cancer
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  81. Apr 2022
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    Hexokinase 1 cellular localization regulates the metabolic fate of glucose
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    Ligand-independent oligomerization of TACI is controlled by the transmembrane domain and regulates proliferation of activated B cells
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    Caveolin-1 Peptide Regulates p53-microRNA-34a Feedback in Fibrotic Lung Fibroblasts
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    Chk1 dynamics in G2 phase upon replication stress predict daughter cell outcome
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  91. Feb 2022
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    Transgenerational inheritance of sexual attractiveness via small RNAs enhances evolvability in C. elegans
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    Acriflavine, a clinically approved drug, inhibits SARS-CoV-2 and other betacoronaviruses
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    TRACE generates fluorescent human reporter cell lines to characterize epigenetic pathways
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    Disrupted expression of mitochondrial NCLX sensitizes neuroglial networks to excitotoxic stimuli and renders synaptic activity toxic
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    Ataxin-2 is essential for cytoskeletal dynamics and neurodevelopment in Drosophila
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    Patched 1 reduces the accessibility of cholesterol in the outer leaflet of membranes
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    Functional consequences of postnatal interventions in a mouse model of Fragile X syndrome
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    A general role for TANGO1, encoded by MIA3, in secretory pathway organization and function
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  105. Oct 2021
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    p38-mediated cell growth and survival drive rapid embryonic wound repair
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    FSTL3 Neutralizing Antibodies Enhance Glucose-Responsive Insulin Secretion In Dysfunctional Male Mouse And Human Islets
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  109. Sep 2021
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    Revisiting astrocyte to neuron conversion with lineage tracing in vivo
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    Viral targeting of glioblastoma stem cells with patient-specific genetic and post-translational p53 deregulations
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  114. Aug 2021
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    The Catalytic Subunit β of PKA Affects Energy Balance and Catecholaminergic Activity
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    Fcγ receptor activation mediates vascular inflammation and abdominal aortic aneurysm development
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    Integrin-Linked Kinase Mediates Therapeutic Resistance of Quiescent CML Stem Cells to Tyrosine Kinase Inhibitors
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    A Membrane-Tethered Ubiquitination Pathway Regulates Hedgehog Signaling and Heart Development
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    A Non-canonical BRCT-Phosphopeptide Recognition Mechanism Underlies RhoA Activation in Cytokinesis
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    CD81 Controls Beige Fat Progenitor Cell Growth and Energy Balance via FAK Signaling
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    Reduction of Liver Metastasis Stiffness Improves Response to Bevacizumab in Metastatic Colorectal Cancer
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  131. Feb 2021
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    A Therapeutic Non-self-reactive SARS-CoV-2 Antibody Protects from Lung Pathology in a COVID-19 Hamster Model
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    Early life adversity decreases pre-adolescent fear expression by accelerating amygdala PV cell development
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    Competition between PRC2.1 and 2.2 subcomplexes regulates PRC2 chromatin occupancy in human stem cells
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    Generation of a WA14 hESC sub-line carrying a hemizygous ABCD1 (C.1696_1710 del) mutation introduced by CRISPR/Cas9 technology
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  136. Jan 2021
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  138. Dec 2020
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    CDK8 Fine-Tunes IL-6 Transcriptional Activities by Limiting STAT3 Resident Time at the Gene Loci
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    ARL8 Relieves SKIP Autoinhibition to Enable Coupling of Lysosomes to Kinesin-1
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    Smoothelin-like 2 Inhibits Coronin-1B to Stabilize the Apical Actin Cortex during Epithelial Morphogenesis
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  143. Oct 2020
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    Ordered dephosphorylation initiated by the selective proteolysis of cyclin B drives mitotic exit
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    BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain
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    GLI transcriptional repression regulates tissue-specific enhancer activity in response to Hedgehog signaling
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    GDE2-Dependent Activation of Canonical Wnt Signaling in Neurons Regulates Oligodendrocyte Maturation
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    Doublecortin like kinase 1 regulates α-Synuclein levels and toxicity
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    Synaptic Vesicle Precursors and Lysosomes Are Transported by Different Mechanisms in the Axon of Mammalian Neurons
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    Acute pharmacological inhibition of matrix metalloproteinase‐9 activity during development restores perineuronal net formation and normalizes auditory processing in Fmr1 KO mice
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    Astrocytic Ephrin-B1 Controls Synapse Formation in the Hippocampus During Learning and Memory
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    Neuronal and synaptic morphological alterations in the hippocampus of cannabinoid receptor type 1 knockout mice
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    Quality Control of ER Membrane Proteins by the RNF185/Membralin Ubiquitin Ligase Complex
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    Autophagic Degradation of NBR1 Restricts Metastatic Outgrowth during Mammary Tumor Progression
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    Derivation of a human induced pluripotent stem cell line (QBRIi007-A) from a patient carrying a homozygous intronic mutation (c.613-7T>G) in the SLC2A2 gene
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    Inter-dependent Centrosomal Co-localization of the cen and ik2 cis-Natural Antisense mRNAs in Drosophila
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    Renal Purge of Hemolymphatic Lipids Prevents the Accumulation of ROS-Induced Inflammatory Oxidized Lipids and Protects Drosophila from Tissue Damage
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    Transcriptional States and Chromatin Accessibility Underlying Human Erythropoiesis
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    The G2-to-M Transition Is Ensured by a Dual Mechanism that Protects Cyclin B from Degradation by Cdc20-Activated APC/C
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    Differential Activation of the Transcription Factor IRF1 Underlies the Distinct Immune Responses Elicited by Type I and III Interferons
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    A CEP104-CSPP1 Complex Is Required for Formation of Primary Cilia Competent in Hedgehog Signaling
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    PI31 Is an Adaptor Protein for Proteasome Transport in Axons and Required for Synaptic Development
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    Beneficial effects of sound exposure on auditory cortex development in a mouse model of Fragile X Syndrome
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    Deletion of Fmr1 from Forebrain Excitatory Neurons Triggers Abnormal Cellular, EEG, and Behavioral Phenotypes in the Auditory Cortex of a Mouse Model of Fragile X Syndrome
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    MALT1 Phosphorylation Controls Activation of T Lymphocytes and Survival of ABC-DLBCL Tumor Cells
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    UCP2 Deficiency Increases Colon Tumorigenesis by Promoting Lipid Synthesis and Depleting NADPH for Antioxidant Defenses
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  176. www.jneurosci.org www.jneurosci.org
    Functional Consequences of Synapse Remodeling Following Astrocyte-Specific Regulation of Ephrin-B1 in the Adult Hippocampus
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      DOI: 10.1523/JNEUROSCI.3618-17.2018

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    The polysialic acid mimetics idarubicin and irinotecan stimulate neuronal survival and neurite outgrowth and signal via protein kinase C
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      DOI: 10.1111/jnc.14076

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    Oxidative Stress Orchestrates Cell Polarity to Promote Embryonic Wound Healing
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    WDR5 Stabilizes Actin Architecture to Promote Multiciliated Cell Formation
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    Cross Talk between One-Carbon Metabolism, Eph Signaling, and Histone Methylation Promotes Neural Stem Cell Differentiation
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    Ribosome Levels Selectively Regulate Translation and Lineage Commitment in Human Hematopoiesis
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    PTEN negatively regulates the cell lineage progression from NG2+ glial progenitor to oligodendrocyte via mTOR-independent signaling
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    Repression of Adipose Tissue Fibrosis through a PRDM16-GTF2IRD1 Complex Improves Systemic Glucose Homeostasis
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    RAPGEF5 Regulates Nuclear Translocation of β-Catenin
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    Jak2-mediated phosphorylation of Atoh1 is critical for medulloblastoma growth.
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  191. Nov 2017
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    Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling
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    An Atoh1-S193A phospho-mutant allele causes hearing deficits and motor impairment
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    YAP/TAZ Orchestrate VEGF Signaling during Developmental Angiogenesis
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    Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling
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    PPARβ Is Essential for Maintaining Normal Levels of PGC-1α and Mitochondria and for the Increase in Muscle Mitochondria Induced by Exercise
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      RRID:AB_2340770 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S155041311730236X
  198. elifesciences.org elifesciences.org
    p27Kip1 promotes invadopodia turnover and invasion through the regulation of the PAK1/Cortactin pathway
    1
    1. scibot 08 Nov 2017
      AB_2340770

      Curator: @kaitlinsung

      Resource used:

      (Jackson ImmunoResearch Labs Cat# 715-035-150, RRID:AB_2340770)

      SciCrunch record: RRID:AB_2340770

      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:AB_2340770 RRIDCUR:Validated
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    elifesciences.org/content/6/e22207
  199. www.jneurosci.org www.jneurosci.org
    Progressive Disorganization of Paranodal Junctions and Compact Myelin Due to Loss of DCC Expression by Oligodendrocytes
    1
    1. scibot 08 Nov 2017
      715-035-150

      Curator: @gabimpine

      Resource used:

      (Jackson ImmunoResearch Labs Cat# 715-035-150, RRID:AB_2340770)

      SciCrunch record: RRID:AB_2340770

      Alternate resolvers: SciCrunch xml N2T identifiers.org

      What is this?

      RRID:AB_2340770 RRIDCUR:Missing
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    jneurosci.org/content/34/29/9768.long