50 Matching Annotations
  1. Jun 2024
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    Time-resolved fate mapping identifies the intestinal upper crypt zone as an origin of Lgr5+ crypt base columnar cells
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    1. scibot 07 Jun 2024
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      DOI: 10.1016/j.cell.2024.05.001

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    sciencedirect.com/science/article/pii/S0092867424004914
  3. May 2024
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    Epithelial aPKC deficiency leads to stem cell loss preceding metaplasia in colorectal cancer initiation
    1
    1. scibot 30 May 2024
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      DOI: 10.1016/j.devcel.2024.05.001

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    sciencedirect.com/science/article/pii/S1534580724002995
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    Tuft cell acetylcholine is released into the gut lumen to promote anti-helminth immunity
    1
    1. scibot 14 May 2024
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      DOI: 10.1016/j.immuni.2024.04.018

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    sciencedirect.com/science/article/pii/S1074761324002231
  6. Apr 2024
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    NIBR-LTSi is a selective LATS kinase inhibitor activating YAP signaling and expanding tissue stem cells in vitro and in vivo
    1
    1. scibot 05 Apr 2024
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      DOI: 10.1016/j.stem.2024.03.003

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    sciencedirect.com/science/article/pii/S1934590924000845
  8. Feb 2024
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    Microbiota-derived butyrate restricts tuft cell differentiation via histone deacetylase 3 to modulate intestinal type 2 immunity
    1
    1. scibot 07 Feb 2024
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      DOI: 10.1016/j.immuni.2024.01.002

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    sciencedirect.com/science/article/pii/S107476132400027X
  10. Aug 2023
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    Adrenergic nerves regulate intestinal regeneration through IL-22 signaling from type 3 innate lymphoid cells
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    1. scibot 29 Aug 2023
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      DOI: 10.1016/j.stem.2023.07.013

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    sciencedirect.com/science/article/pii/S1934590923002588
  12. May 2023
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    M cell maturation and cDC activation determine the onset of adaptive immune priming in the neonatal Peyer’s patch
    1
    1. scibot 03 May 2023
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      DOI: 10.1016/j.immuni.2023.04.002

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    sciencedirect.com/science/article/pii/S107476132300170X
  14. Apr 2023
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    Smooth muscle contributes to the development and function of a layered intestinal stem cell niche
    1
    1. scibot 20 Apr 2023
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      DOI: 10.1016/j.devcel.2023.02.012

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    sciencedirect.com/science/article/pii/S1534580723000709
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    Graded BMP signaling within intestinal crypt architecture directs self-organization of the Wnt-secreting stem cell niche
    1
    1. scibot 07 Apr 2023
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      DOI: 10.1016/j.stem.2023.03.004

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    sciencedirect.com/science/article/pii/S1934590923000759
  17. Jan 2023
  18. www.sciencedirect.com www.sciencedirect.com
    A DLG1-ARHGAP31-CDC42 axis is essential for the intestinal stem cell response to fluctuating niche Wnt signaling
    1
    1. scibot 19 Jan 2023
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      DOI: 10.1016/j.stem.2022.12.008

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    sciencedirect.com/science/article/pii/S1934590922004921
  19. Dec 2022
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mother cells control daughter cell proliferation in intestinal organoids to minimize proliferation fluctuations
    1
    1. scibot 02 Dec 2022
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      DOI: 10.7554/eLife.80682

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    ncbi.nlm.nih.gov/pmc/articles/PMC9708068/
  21. Nov 2022
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    A dietary change to a high-fat diet initiates a rapid adaptation of the intestine
    1
    1. scibot 16 Nov 2022
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      DOI: 10.1016/j.celrep.2022.111641

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    sciencedirect.com/science/article/pii/S2211124722015121
  23. May 2022
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    Targeted ablation of Lgr5-expressing intestinal stem cells in diphtheria toxin receptor-based mouse and organoid models
    1
    1. scibot 20 May 2022
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      DOI: 10.1016/j.xpro.2022.101411

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    sciencedirect.com/science/article/pii/S266616672200291X
  25. Dec 2021
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Rpl24Bst mutation suppresses colorectal cancer by promoting eEF2 phosphorylation via eEF2K
    1
    1. scibot 17 Dec 2021
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      DOI: 10.7554/eLife.69729

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    ncbi.nlm.nih.gov/pmc/articles/PMC8668188/
  27. www.sciencedirect.com www.sciencedirect.com
    Generation of mixed murine organoids to model cellular interactions
    1
    1. scibot 09 Dec 2021
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      DOI: 10.1016/j.xpro.2021.100997

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    sciencedirect.com/science/article/pii/S2666166721007036
  28. Oct 2021
  29. www.nature.com www.nature.com
    Controlling the polarity of human gastrointestinal organoids to investigate epithelial biology and infectious diseases
    1
    1. scibot 23 Oct 2021
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      DOI: 10.1038/s41596-021-00607-0

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    nature.com/articles/s41596-021-00607-0
  30. Sep 2021
  31. www.sciencedirect.com www.sciencedirect.com
    SATB2 preserves colon stem cell identity and mediates ileum-colon conversion via enhancer remodeling
    1
    1. scibot 28 Sep 2021
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      DOI: 10.1016/j.stem.2021.09.004

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    sciencedirect.com/science/article/pii/S1934590921003805
  32. Aug 2021
  33. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 10 Aug 2021
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      DOI: 10.1016/j.immuni.2018.09.013

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    sciencedirect.com/science/article/pii/S107476131830428X
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    1. scibot 03 Aug 2021
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      DOI: 10.1016/j.celrep.2019.01.108

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    ncbi.nlm.nih.gov/pmc/articles/PMC6391775/
  35. Jul 2021
  36. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 31 Jul 2021
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      DOI: 10.1016/j.stem.2016.11.001

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    sciencedirect.com/science/article/pii/S1934590916303976
  37. www.sciencedirect.com www.sciencedirect.com
    T Helper Cell Cytokines Modulate Intestinal Stem Cell Renewal and Differentiation
    1
    1. scibot 30 Jul 2021
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      DOI: 10.1016/j.cell.2018.10.008

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    sciencedirect.com/science/article/pii/S0092867418313163
  38. bmcbiol.biomedcentral.com bmcbiol.biomedcentral.com
    Harnessing single-cell genomics to improve the physiological fidelity of organoid-derived cell types
    1
    1. scibot 29 Jul 2021
      RRID:AB_2341230

      DOI: 10.1186/s12915-018-0527-2

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    bmcbiol.biomedcentral.com/articles/10.1186/s12915-018-0527-2
  39. academic.oup.com academic.oup.com
    Quantitative Proteomics of Intestinal Mucosa From Male Mice Lacking Intestinal Epithelial Insulin Receptors
    1
    1. scibot 28 Jul 2021
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      DOI: 10.1210/en.2017-00194

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    academic.oup.com/endo/article/158/8/2470/3861926/Quantitative-Proteomics-of-Intestinal-Mucosa-From
  40. May 2021
  41. www.sciencedirect.com www.sciencedirect.com
    A suite of new Dre recombinase drivers markedly expands the ability to perform intersectional genetic targeting
    1
    1. scibot 09 May 2021
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      DOI: 10.1016/j.stem.2021.01.007

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    sciencedirect.com/science/article/pii/S1934590921000072
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    Mapping Development of the Human Intestinal Niche at Single-Cell Resolution
    1
    1. scibot 09 May 2021
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      DOI: 10.1016/j.stem.2020.11.008

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    sciencedirect.com/science/article/pii/S1934590920305464
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    Mesenchymal Niche-Derived Neuregulin-1 Drives Intestinal Stem Cell Proliferation and Regeneration of Damaged Epithelium
    1
    1. scibot 09 May 2021
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      DOI: 10.1016/j.stem.2020.06.021

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    sciencedirect.com/science/article/pii/S1934590920302885
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    Regenerative Reprogramming of the Intestinal Stem Cell State via Hippo Signaling Suppresses Metastatic Colorectal Cancer
    1
    1. scibot 09 May 2021
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      DOI: 10.1016/j.stem.2020.07.003

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    sciencedirect.com/science/article/pii/S1934590920303416
  45. www-sciencedirect-com.ezproxy.auckland.ac.nz www-sciencedirect-com.ezproxy.auckland.ac.nz
    Transit-Amplifying Cells Coordinate Changes in Intestinal Epithelial Cell-Type Composition
    1
    1. scibot 06 May 2021
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      DOI: 10.1016/j.devcel.2020.12.020

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    www-sciencedirect-com.ezproxy.auckland.ac.nz/science/article/pii/S1534580720310261
  46. Apr 2021
  47. www.sciencedirect.com www.sciencedirect.com
    Mitochondria Define Intestinal Stem Cell Differentiation Downstream of a FOXO/Notch Axis
    1
    1. scibot 29 Apr 2021
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      DOI: 10.1016/j.cmet.2020.10.005

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    sciencedirect.com/science/article/pii/S1550413120305386
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    Emergence of a High-Plasticity Cell State during Lung Cancer Evolution
    1
    1. scibot 20 Apr 2021
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      DOI: 10.1016/j.ccell.2020.06.012

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    sciencedirect.com/science/article/pii/S1535610820303160
  49. Mar 2021
  50. www.sciencedirect.com www.sciencedirect.com
    Exploring the human lacrimal gland using organoids and single-cell sequencing
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    1. scibot 24 Mar 2021
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      DOI: 10.1016/j.stem.2021.02.024

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    sciencedirect.com/science/article/pii/S1934590921000758
  51. Jan 2021
  52. www.sciencedirect.com www.sciencedirect.com
    A constant pool of Lgr5+ intestinal stem cells is required for intestinal homeostasis
    1
    1. scibot 27 Jan 2021
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      DOI: 10.1016/j.celrep.2020.108633

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    sciencedirect.com/science/article/pii/S2211124720316223
  53. Dec 2020
  54. elifesciences.org elifesciences.org
    Autophagy compensates for Lkb1 loss to maintain adult mice homeostasis and survival
    1
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      DOI: 10.7554/eLife.62377

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    elifesciences.org/articles/62377
  55. Sep 2020
  56. www.sciencedirect.com www.sciencedirect.com
    Distinct Mesenchymal Cell Populations Generate the Essential Intestinal BMP Signaling Gradient
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      DOI: 10.1016/j.stem.2020.01.008

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    sciencedirect.com/science/article/pii/S1934590920300084
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    Calorie Restriction Increases the Number of Competing Stem Cells and Decreases Mutation Retention in the Intestine
    1
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      DOI: 10.1016/j.celrep.2020.107937

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    sciencedirect.com/science/article/pii/S2211124720309189
  58. journals.physiology.org journals.physiology.org
    Grading TESI: Crypt and villus formation in tissue-engineered small intestine alters with stem/progenitor cell source | American Journal of Physiology-Gastrointestinal and Liver Physiology
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      AB_2341230

      DOI: 10.1152/ajpgi.00387.2019

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      Curator comments: Polyclonal Rabbit Anti Human Lysozyme EC 3.2.1.17 antibody Agilent Cat# A0099

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    journals.physiology.org/doi/full/10.1152/ajpgi.00387.2019
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Duodenum Intestine-Chip for preclinical drug assessment in a human relevant model
    1
    1. scibot 03 Sep 2020
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      DOI: 10.7554/eLife.50135

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    ncbi.nlm.nih.gov/pmc/articles/PMC6959988/
  60. Jan 2020
  61. www.sciencedirect.com www.sciencedirect.com
    T Cell Recruitment to the Intestinal Stem Cell Compartment Drives Immune-Mediated Intestinal Damage after Allogeneic Transplantation
    1
    1. scibot 13 Jan 2020
      RRID:AB_2341230

      DOI: 10.1016/j.immuni.2019.06.003

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    sciencedirect.com/science/article/pii/S1074761319302481
  62. www.sciencedirect.com www.sciencedirect.com
    PRDM16 Maintains Homeostasis of the Intestinal Epithelium by Controlling Region-Specific Metabolism
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    1. scibot 13 Jan 2020
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      DOI: 10.1016/j.stem.2019.08.017

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    sciencedirect.com/science/article/pii/S1934590919303844
  63. www.sciencedirect.com www.sciencedirect.com
    Controlling Epithelial Polarity: A Human Enteroid Model for Host-Pathogen Interactions
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      DOI: 10.1016/j.celrep.2019.01.108

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  64. Nov 2018
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    Self-Maintaining Gut Macrophages Are Essential for Intestinal Homeostasis
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    Paneth Cells Respond to Inflammation and Contribute to Tissue Regeneration by Acquiring Stem-like Features through SCF/c-Kit Signaling
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    1. scibot 05 Nov 2018
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    YAP/TAZ-Dependent Reprogramming of Colonic Epithelium Links ECM Remodeling to Tissue Regeneration
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  71. Nov 2017
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    Generation of Mouse and Human Organoid-Forming Intestinal Progenitor Cells by Direct Lineage Reprogramming
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    Intestinal Enteroendocrine Lineage Cells Possess Homeostatic and Injury-Inducible Stem Cell Activity
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    Mex3a Marks a Slowly Dividing Subpopulation of Lgr5+ Intestinal Stem Cells
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    Induced Quiescence of Lgr5+ Stem Cells in Intestinal Organoids Enables Differentiation of Hormone-Producing Enteroendocrine Cells
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