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52 Matching Annotations

Jul 2025
www.cell.com www.cell.com

A cereblon-based glue degrader of NEK7 regulates NLRP3 inflammasome in a context-dependent manner

1
1. scibot 15 Jul 2025
  
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  DOI: 10.1016/j.chembiol.2025.06.005
  
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cell.com/cell-chemical-biology/fulltext/S2451-9456(25)00200-4
Apr 2025
www.sciencedirect.com www.sciencedirect.com

Red blood cells undergo lytic programmed cell death involving NLRP3

1
1. scibot 19 Apr 2025
  
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  DOI: 10.1016/j.cell.2025.03.039
  
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sciencedirect.com/science/article/pii/S0092867425003897
52.53.155.43 52.53.155.43

Lysosome positioning affects NLRP3 inflammasome activation

1
1. scibot 03 Apr 2025
  
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  AB_2490440
  
  DOI: 10.1101/2025.03.21.644552
  
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52.53.155.43/5e725b42faf6f4894ebfb1897ac6165b04d7cac3/PDF-html.html
Jan 2025
www.sciencedirect.com www.sciencedirect.com

A cis-regulatory element controls expression of histone deacetylase 9 to fine-tune inflammasome-dependent chronic inflammation in atherosclerosis

1
1. scibot 30 Jan 2025
  
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  DOI: 10.1016/j.immuni.2025.01.003
  
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sciencedirect.com/science/article/pii/S1074761325000263
Sep 2024
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

BPS Publications

1
1. scibot 27 Sep 2024
  
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  RRID:AB_2490440
  
  DOI: 10.1111/bph.17320
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.17320
Jul 2024
link.springer.com link.springer.com

Biflavonoid Methylchamaejasmin and Khaya grandifoliola Extract Inhibit NLRP3 Inflammasome in THP-1 Cell Model of Neuroinflammation

1
1. scibot 23 Jul 2024
  
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  DOI: 10.1007/s12035-024-04365-4
  
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link.springer.com/article/10.1007/s12035-024-04365-4
Jun 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

NLRC5 senses NAD+ depletion, forming a PANoptosome and driving PANoptosis and inflammation

1
1. scibot 21 Jun 2024
  
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  DOI: 10.1016/j.cell.2024.05.034
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11283362/
Apr 2024
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Truncating NFKB1 variants cause combined NLRP3 inflammasome activation and type I interferon signaling and predispose to necrotizing fasciitis

2
1. scibot 09 Apr 2024
  
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  RRID:AB_2885200
  
  DOI: 10.1016/j.xcrm.2024.101503
  
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2. scibot 09 Apr 2024
  
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  RRID:AB_2885200
  
  DOI: 10.1016/j.xcrm.2024.101503
  
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sciencedirect.com/science/article/pii/S2666379124001721
Feb 2024
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Disruption of the Na+/K+-ATPase-purinergic P2X7 receptor complex in microglia promotes stress-induced anxiety

1
1. scibot 23 Feb 2024
  
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  DOI: 10.1016/j.immuni.2024.01.018
  
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sciencedirect.com/science/article/pii/S107476132400044X
Nov 2023
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Gasdermin D permeabilization of mitochondrial inner and outer membranes accelerates and enhances pyroptosis

1
1. scibot 10 Nov 2023
  
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  DOI: 10.1016/j.immuni.2023.10.004
  
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sciencedirect.com/science/article/pii/S1074761323004442
www.nature.com www.nature.com

Cryo-electron tomography of NLRP3-activated ASC complexes reveals organelle co-localization

1
1. scibot 10 Nov 2023
  
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  RRID:AB_2490440
  
  DOI: 10.1038/s41467-023-43180-8
  
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nature.com/articles/s41467-023-43180-8
Mar 2023
onlinelibrary.wiley.com onlinelibrary.wiley.com

NLRP3-directed antisense oligonucleotides reduce microglial immunoactivities in vitro

1
1. scibot 30 Mar 2023
  
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  RRID:AB_2490440
  
  DOI: 10.1111/jnc.15778
  
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onlinelibrary.wiley.com/doi/10.1111/jnc.15778
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

CARD-only proteins regulate in vivo inflammasome responses and ameliorate gout

1
1. scibot 17 Mar 2023
  
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  RRID:AB_2490440
  
  DOI: 10.1016/j.celrep.2023.112265
  
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pubmed.ncbi.nlm.nih.gov/36930645/
Jan 2023
www.sciencedirect.com www.sciencedirect.com

The NLRP1 and CARD8 inflammasomes detect reductive stress

1
1. scibot 19 Jan 2023
  
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  RRID:AB_2490440
  
  DOI: 10.1016/j.celrep.2022.111966
  
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sciencedirect.com/science/article/pii/S2211124722018708
www.sciencedirect.com www.sciencedirect.com

Pyruvate dehydrogenase kinase supports macrophage NLRP3 inflammasome activation during acute inflammation

1
1. scibot 11 Jan 2023
  
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  RRID:AB_2490440
  
  DOI: 10.1016/j.celrep.2022.111941
  
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sciencedirect.com/science/article/pii/S2211124722018423
Nov 2022
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Neutrophil inflammasomes sense the subcellular delivery route of translocated bacterial effectors and toxins

1
1. scibot 24 Nov 2022
  
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  AB_2490440
  
  DOI: 10.1016/j.celrep.2022.111688
  
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sciencedirect.com/science/article/pii/S2211124722015625
www.science.org www.science.org

Caspase-8 inactivation drives autophagy-dependent inflammasome activation in myeloid cells

1
1. scibot 15 Nov 2022
  
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  RRID:AB_2490440
  
  DOI: 10.1126/sciadv.abn9912
  
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science.org/doi/10.1126/sciadv.abn9912
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

P38 kinases mediate NLRP1 inflammasome activation after ribotoxic stress response and virus infection

1
1. scibot 04 Nov 2022
  
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  RRID:AB_2490440
  
  DOI: 10.1084/jem.20220837
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9623368/
Mar 2022
link.springer.com link.springer.com

Reconstitution System of NLRP3 Inflammasome in HEK293T Cells

1
1. scibot 23 Mar 2022
  
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  RRID:AB_2490440
  
  DOI: 10.1007/978-1-0716-2144-8_8
  
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link.springer.com/protocol/10.1007/978-1-0716-2144-8_8
Feb 2022
www.sciencedirect.com www.sciencedirect.com

Listeria toxin promotes phosphorylation of the inflammasome adaptor ASC through Lyn and Syk to exacerbate pathogen expansion

1
1. scibot 23 Feb 2022
  
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  RRID:AB_2490440
  
  DOI: 10.1016/j.celrep.2022.110414
  
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sciencedirect.com/science/article/pii/S2211124722001383
Oct 2021
www.sciencedirect.com www.sciencedirect.com

Peli1 facilitates NLRP3 inflammasome activation by mediating ASC ubiquitination

1
1. scibot 30 Oct 2021
  
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  RRID:AB_2490440
  
  DOI: 10.1016/j.celrep.2021.109904
  
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sciencedirect.com/science/article/pii/S2211124721013747
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Synthetic amyloid-β oligomers drive early pathological progression of Alzheimer’s disease in nonhuman primates

1
1. scibot 28 Oct 2021
  
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  RRID:AB_2490440
  
  DOI: 10.1016/j.isci.2021.103207
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8524197/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Sacubitril/Valsartan Alleviates Experimental Autoimmune Myocarditis by Inhibiting Th17 Cell Differentiation Independently of the NLRP3 Inflammasome Pathway

1
1. scibot 02 Oct 2021
  
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  AB_2490440
  
  DOI: 10.3389/fphar.2021.727838
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8479108/
Aug 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Shigella OspC3 suppresses murine cytosolic LPS sensing

1
1. scibot 19 Aug 2021
  
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  RRID:AB_2490440
  
  DOI: 10.1016/j.isci.2021.102910
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8361271/
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Untitled document

1
1. scibot 08 Aug 2021
  
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  RRID:AB_2490440
  
  DOI: 10.1016/j.celrep.2018.09.071
  
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sciencedirect.com/science/article/pii/S2211124718315316
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

1
1. scibot 06 Aug 2021
  
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  RRID:AB_2490440
  
  DOI: 10.1016/j.immuni.2019.02.006
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6477154/
Jul 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

1
1. scibot 31 Jul 2021
  
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  RRID:AB_2490440
  
  DOI: 10.1016/j.celrep.2019.03.100
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6486487/
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The NLRP6 Inflammasome Recognizes Lipoteichoic Acid and Regulates Gram-Positive Pathogen Infection

1
1. scibot 30 Jul 2021
  
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  RRID:AB_2490440
  
  DOI: 10.1016/j.cell.2018.09.047
  
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  Curator: @Jmenke
  
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  RRIDCUR:Validated RRID:AB_2490440
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sciencedirect.com/science/article/pii/S0092867418312595
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Ketogenic diet restrains aging-induced exacerbation of coronavirus infection in mice

1
1. scibot 08 Jul 2021
  
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  RRID:AB_2490440
  
  DOI: 10.7554/eLife.66522
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8245129/
May 2021
www.sciencedirect.com www.sciencedirect.com

Histone Deacetylase 3 Couples Mitochondria to Drive IL-1β-Dependent Inflammation by Configuring Fatty Acid Oxidation

1
1. scibot 07 May 2021
  
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  RRID:AB_2490440
  
  DOI: 10.1016/j.molcel.2020.08.015
  
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sciencedirect.com/science/article/pii/S1097276520305785
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Caspase-8-Dependent Inflammatory Responses Are Controlled by Its Adaptor, FADD, and Necroptosis

1
1. scibot 06 May 2021
  
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  RRID:AB_2490440
  
  DOI: 10.1016/j.immuni.2020.04.010
  
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sciencedirect.com/science/article/pii/S1074761320301680
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DNA Damage Promotes Epithelial Hyperplasia and Fate Mis-specification via Fibroblast Inflammasome Activation

1
1. scibot 05 May 2021
  
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  RRID:AB_2490440
  
  DOI: 10.1016/j.devcel.2020.09.021
  
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sciencedirect.com/science/article/pii/S153458072030753X
Mar 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Pin1 Promotes NLRP3 Inflammasome Activation by Phosphorylation of p38 MAPK Pathway in Septic Shock

1
1. scibot 13 Mar 2021
  
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  AB_2490440
  
  DOI: 10.3389/fimmu.2021.620238
  
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  Curator: @evieth
  
  SciCrunch record: RRID:AB_2490440
  
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  RRIDCUR:Validated RRID:AB_2490440
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ncbi.nlm.nih.gov/pmc/articles/PMC7947244/
Feb 2021
www.nature.com www.nature.com

A comprehensive guide to studying inflammasome activation and cell death

1
1. scibot 26 Feb 2021
  
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  RRID:AB_2490440
  
  DOI: 10.1038/s41596-020-0374-9
  
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nature.com/articles/s41596-020-0374-9
onlinelibrary.wiley.com onlinelibrary.wiley.com

α‐Synuclein evokes NLRP3 inflammasome‐mediated IL‐1β secretion from primary human microglia

2
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  DOI: 10.1002/glia.23970
  
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  DOI: 10.1002/glia.23970
  
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Inflammasomes within Hyperactive Murine Dendritic Cells Stimulate Long-Lived T Cell-Mediated Anti-tumor Immunity

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1. scibot 24 Nov 2020
  
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  DOI: 10.1016/j.celrep.2020.108381
  
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Soluble Aβ Oligomers and Protofibrils Induce NLRP3 Inflammasome Activation in Microglia

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1. scibot 23 Sep 2020
  
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  DOI: 10.1111/jnc.14945
  
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β-Amyloid Clustering around ASC Fibrils Boosts Its Toxicity in Microglia

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  DOI: 10.1016/j.celrep.2020.02.025
  
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FADD and Caspase-8 Regulate Gut Homeostasis and Inflammation by Controlling MLKL- and GSDMD-Mediated Death of Intestinal Epithelial Cells

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1. scibot 15 Sep 2020
  
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  DOI: 10.1016/j.immuni.2020.04.002
  
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An Apoptotic Caspase Network Safeguards Cell Death Induction in Pyroptotic Macrophages

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  DOI: 10.1016/j.celrep.2020.107959
  
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Adrenergic Signaling in Muscularis Macrophages Limits Infection-Induced Neuronal Loss

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.cell.2019.12.002
  
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Untitled document

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  DOI: 10.1016/j.immuni.2019.02.006
  
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Untitled document

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  DOI: 10.1016/j.celrep.2019.03.100
  
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Cholesterol Homeostatic Regulator SCAP-SREBP2 Integrates NLRP3 Inflammasome Activation and Cholesterol Biosynthetic Signaling in Macrophages

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1. scibot 05 Nov 2018
  
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A Method for the Acute and Rapid Degradation of Endogenous Proteins

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Activation of the NLRP3 inflammasome in microglia: the role of ceramide

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Induced-Pluripotent-Stem-Cell-Derived Primitive Macrophages Provide a Platform for Modeling Tissue-Resident Macrophage Differentiation and Function

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Germline NLRP1 Mutations Cause Skin Inflammatory and Cancer Susceptibility Syndromes via Inflammasome Activation

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IRGB10 Liberates Bacterial Ligands for Sensing by the AIM2 and Caspase-11-NLRP3 Inflammasomes

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