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Tau-driven hyperexcitability of locus coeruleus noradrenergic neurons underlies sleep fragmentation and cognitive decline in mice

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1. scibot 07 Nov 2026
  
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  DOI: 10.1016/j.celrep.2026.118273
  
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sciencedirect.com/science/article/pii/S2211124726013525
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Deciphering early tau pathology events using an Alzheimer’s disease-seeded organotypic hippocampal slice culture model

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1. scibot 06 Nov 2026
  
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  DOI: 10.1016/j.isci.2026.118083
  
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sciencedirect.com/science/article/pii/S2589004226034668
Oct 2026
dx.doi.org dx.doi.org

Comparative neuropathological evaluation of pT217 immunoreactivity in human and transgenic mouse tauopathies

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1. scibot 29 Oct 2026
  
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  RRID:AB_2533745
  
  DOI: 10.1093/jnen/nlag103
  
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dx.doi.org/10.1093/jnen/nlag103
Feb 2026
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Neuronal PPP2R5C in plasma is a potential biomarker for early diagnosis of Alzheimer’s disease

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1. scibot 20 Feb 2026
  
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  RRID:AB_2533745
  
  DOI: 10.1016/j.xcrm.2026.102631
  
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sciencedirect.com/science/article/pii/S2666379126000480
May 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Parvalbumin interneurons in the hippocampal formation of individuals with Alzheimer’s disease: a neuropathological study of abnormal phosphorylated tau in neurons

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1. scibot 21 May 2025
  
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  DOI: 10.3389/fnana.2025.1571514
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12018435/
Apr 2025
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A Cdk5 inhibitor restores cognitive function and alleviates type 2 diabetes in mice

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1. scibot 01 Apr 2025
  
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  RRID:AB_2533745
  
  DOI: 10.1016/j.isci.2025.112200
  
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sciencedirect.com/science/article/pii/S2589004225004614
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iPSC screening identifies CACNA2D2 as a potential therapeutic target for FTLD-Tau

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1. scibot 01 Apr 2025
  
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  DOI: 10.1016/j.ejcb.2025.151484
  
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sciencedirect.com/science/article/pii/S0171933525000093
Sep 2022
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A next-generation iPSC-derived forebrain organoid model of tauopathy with tau fibrils by AAV-mediated gene transfer

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1. scibot 11 Sep 2022
  
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  RRID:AB_2533745
  
  DOI: 10.1016/j.crmeth.2022.100289
  
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sciencedirect.com/science/article/pii/S2667237522001710
Sep 2021
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IL-17 triggers the onset of cognitive and synaptic deficits in early stages of Alzheimer’s disease

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1. scibot 01 Sep 2021
  
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  DOI: 10.1016/j.celrep.2021.109574
  
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sciencedirect.com/science/article/pii/S2211124721010081
Jul 2021
academic.oup.com academic.oup.com

Negative Regulator of Ubiquitin-Like Protein 1 modulates the autophagy-lysosomal pathway via p62 to facilitate the extracellular release of tau following proteasome impairment

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1. scibot 31 Jul 2021
  
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  tau phosphorylated on S396
  
  DOI: 10.1093/hmg/ddz255
  
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  Curator: @Naa003
  
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academic.oup.com/hmg/advance-article/doi/10.1093/hmg/ddz255/5613690
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ELAVL4, splicing, and glutamatergic dysfunction precede neuron loss in MAPT mutation cerebral organoids

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1. scibot 31 Jul 2021
  
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  DOI: 10.1016/j.cell.2021.07.003
  
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sciencedirect.com/science/article/pii/S0092867421008291
Jun 2021
www.jneurosci.org www.jneurosci.org

Cereblon regulates the proteotoxicity of tau by tuning the chaperone activity of DNAJA1

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1. scibot 29 Jun 2021
  
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  DOI: 10.1523/JNEUROSCI.2494-20.2021
  
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jneurosci.org/content/41/24/5138
Apr 2021
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Tau seeds are subject to aberrant modifications resulting in distinct signatures

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1. scibot 28 Apr 2021
  
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  RRID:AB_2533745
  
  DOI: 10.1016/j.celrep.2021.109037
  
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sciencedirect.com/science/article/pii/S2211124721003533
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5-hydroxymethylcytosine is dynamically regulated during forebrain organoid development and aberrantly altered in Alzheimer’s disease

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1. scibot 28 Apr 2021
  
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  DOI: 10.1016/j.celrep.2021.109042
  
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sciencedirect.com/science/article/pii/S2211124721003582