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Maternal-fetal type I interferon signaling drives TREM2 dysregulation and synaptic dysfunction in neurodevelopmental disorders

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  DOI: 10.1016/j.neuron.2026.04.043
  
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sciencedirect.com/science/article/pii/S0896627326003387
May 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Multiparity exacerbates Aβ accumulation and promotes cellular senescence in a mouse model of amyloidosis

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1. scibot 14 May 2026
  
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  DOI: 10.1186/s12979-026-00565-9
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13154431/
Feb 2026
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Astrocyte-microglia crosstalk through Hevin and Toll-like receptor signaling controls developmental thalamocortical synapse refinement

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1. scibot 20 Feb 2026
  
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  DOI: 10.1016/j.neuron.2025.12.028
  
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sciencedirect.com/science/article/pii/S0896627325009845
Jan 2026
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Neuroligin-2 is ubiquitinated by Nedd4l to control developmental astrocyte morphogenesis

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1. scibot 26 Jan 2026
  
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  DOI: 10.64898/2025.12.15.694023
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12724466/
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Plasticity of synapses innervating spinal motor neurons after spinal cord injury in rhesus monkeys

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1. scibot 13 Jan 2026
  
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  DOI: 10.1093/jnen/nlaf128
  
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dx.doi.org/10.1093/jnen/nlaf128
Oct 2025
www.biorxiv.org www.biorxiv.org

Adolescent Alcohol Exposure Disrupts Astrocyte-Synaptic Structural And Functional Coupling In The Male Dorsal Hippocampus

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1. scibot 21 Oct 2025
  
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  DOI: 10.1101/2025.10.14.682478
  
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biorxiv.org/content/10.1101/2025.10.14.682478v1
Jul 2025
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Excitatory-neuron-derived interleukin-34 supports cortical developmental microglia function

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1. scibot 02 Jul 2025
  
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  DOI: 10.1016/j.immuni.2025.06.002
  
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sciencedirect.com/science/article/pii/S1074761325002493
Apr 2025
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Astrocytic polyamine transport by ATP13A4 tunes excitatory synaptic transmission

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1. scibot 10 Apr 2025
  
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  DOI: 10.1101/2025.04.04.25325117
  
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medrxiv.org/content/10.1101/2025.04.04.25325117v1
Mar 2025
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1-s2.0-S2589004225005565-main-html.html

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1. scibot 28 Mar 2025
  
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  DOI: 10.1016/j.isci.2025.112295
  
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52.53.155.43/60bd8b63b5057b3a2fd52107fc36eb4f600f9b31/1-s2.0-S2589004225005565-main-html.html
Nov 2024
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Accelerated protein retention expansion microscopy using microwave radiation

1
1. scibot 24 Nov 2024
  
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  DOI: 10.1016/j.crmeth.2024.100907
  
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sciencedirect.com/science/article/pii/S2667237524002972
Sep 2024
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SynBot is an open-source image analysis software for automated quantification of synapses

1
1. scibot 10 Sep 2024
  
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  DOI: 10.1016/j.crmeth.2024.100861
  
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sciencedirect.com/science/article/pii/S266723752400239X
Oct 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Sex-Dependent Synaptic Remodeling of the Somatosensory Cortex in Mice With Prenatal Methadone Exposure

1
1. scibot 14 Oct 2023
  
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  DOI: 10.3389/adar.2022.10400
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10569410/
Sep 2023
rupress.org rupress.org

Maternal diet during early gestation influences postnatal taste activity–dependent pruning by microglia

1
1. scibot 23 Sep 2023
  
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  DOI: 10.1084/jem.20212476
  
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rupress.org/jem/article/220/12/e20212476/276286/Maternal-diet-during-early-gestation-influences
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Attachment culture of cortical organoids at the microwell air-liquid interface

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1. scibot 20 Sep 2023
  
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  DOI: 10.1016/j.xpro.2023.102502
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10502426/
Apr 2023
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Glioma epileptiform activity and progression are driven by IGSF3-mediated potassium dysregulation

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1. scibot 27 Apr 2023
  
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  DOI: 10.1016/j.neuron.2023.01.013
  
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sciencedirect.com/science/article/pii/S0896627323000375
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A thalamic-primary auditory cortex circuit mediates resilience to stress

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1. scibot 04 Apr 2023
  
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  DOI: 10.1016/j.cell.2023.02.036
  
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sciencedirect.com/science/article/pii/S0092867423002143
Mar 2023
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Tumor suppressor p53 regulates heat shock factor 1 protein degradation in Huntington’s disease

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1. scibot 04 Mar 2023
  
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  DOI: 10.1016/j.celrep.2023.112198
  
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sciencedirect.com/science/article/pii/S2211124723002097
Feb 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Prenatal methadone exposure selectively alters protein expression in primary motor cortex: Implications for synaptic function

1
1. scibot 17 Feb 2023
  
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  AB_2533914
  
  DOI: 10.3389/fphar.2023.1124108
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9928955/
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GEARBOCS: An Adeno Associated Virus Tool for In Vivo Gene Editing in Astrocytes

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1. scibot 08 Feb 2023
  
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  DOI: 10.1101/2023.01.17.524433
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9884502/
Dec 2022
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Adaptable toolbox to characterize Alzheimer’s disease pathology in mouse models

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  DOI: 10.1016/j.xpro.2022.101891
  
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sciencedirect.com/science/article/pii/S2666166722007717
Nov 2022
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TREM2-independent microgliosis promotes tau-mediated neurodegeneration in the presence of ApoE4

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1. scibot 11 Nov 2022
  
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  DOI: 10.1016/j.neuron.2022.10.022
  
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sciencedirect.com/science/article/pii/S0896627322009552
Aug 2022
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Prenatal environmental stressors impair postnatal microglia function and adult behavior in males

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1. scibot 06 Aug 2022
  
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  DOI: 10.1016/j.celrep.2022.111161
  
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sciencedirect.com/science/article/pii/S2211124722009706
Jun 2022
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Local targets of T-stellate cells in the ventral cochlear nucleus

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1. scibot 22 Jun 2022
  
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  DOI: 10.1002/cne.25378
  
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onlinelibrary.wiley.com/doi/10.1002/cne.25378
May 2022
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Alzheimer risk gene product Pyk2 suppresses tau phosphorylation and phenotypic effects of tauopathy

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1. scibot 05 May 2022
  
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  DOI: 10.1186/s13024-022-00526-y
  
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link.springer.com/article/10.1186/s13024-022-00526-y
Apr 2022
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Concerted type I interferon signaling in microglia and neural cells promotes memory impairment associated with amyloid β plaques

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1. scibot 20 Apr 2022
  
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  DOI: 10.1016/j.immuni.2022.03.018
  
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sciencedirect.com/science/article/pii/S1074761322001418
Mar 2022
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Early stress-induced impaired microglial pruning of excitatory synapses on immature CRH-expressing neurons provokes aberrant adult stress responses

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1. scibot 31 Mar 2022
  
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  DOI: 10.1016/j.celrep.2022.110600
  
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sciencedirect.com/science/article/pii/S2211124722003485
Feb 2022
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Astrocyte-neuron crosstalk through Hedgehog signaling mediates cortical synapse development

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1. scibot 23 Feb 2022
  
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  DOI: 10.1016/j.celrep.2022.110416
  
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pubmed.ncbi.nlm.nih.gov/35196485/
Jan 2022
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Vision-dependent specification of cell types and function in the developing cortex

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  DOI: 10.1016/j.cell.2021.12.022
  
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sciencedirect.com/science/article/pii/S0092867421014859
Sep 2021
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Human microglia states are conserved across experimental models and regulate neural stem cell responses in chimeric organoids

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  DOI: 10.1016/j.stem.2021.08.015
  
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sciencedirect.com/science/article/pii/S1934590921003763
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Environmental Enrichment Rescues Social Behavioral Deficits and Synaptic Abnormalities in Pten Haploinsufficient Mice

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1. scibot 08 Sep 2021
  
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  DOI: 10.3390/genes12091366
  
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mdpi.com/2073-4425/12/9/1366
Jul 2021
elifesciences.org elifesciences.org

Untitled document

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1. scibot 29 Jul 2021
  
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  DOI: 10.7554/eLife.21540
  
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elifesciences.org/articles/21540
europepmc.org europepmc.org

α2δ-1 Signaling Drives Cell Death, Synaptogenesis, Circuit Reorganization, and Gabapentin-Mediated Neuroprotection in a Model of Insult-Induced Cortical Malformation.

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1. scibot 28 Jul 2021
  
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  AB_2533914
  
  DOI: 10.1523/ENEURO.0316-17.2017
  
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2. scibot 27 Jul 2021
  
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  RRID:AB_2533914
  
  DOI: 10.1523/ENEURO.0316-17.2017
  
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europepmc.org/articles/PMC5672548/
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JNK Promotes Epithelial Cell Anoikis by Transcriptional and Post-translational Regulation of BH3-Only Proteins

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1. scibot 27 Jul 2021
  
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  RRID:AB_2533
  
  DOI: 10.1016/j.celrep.2017.10.067
  
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sciencedirect.com/science/article/pii/S2211124717315309
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Neuronal VCP loss of function recapitulates FTLD-TDP pathology

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1. scibot 22 Jul 2021
  
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  DOI: 10.1016/j.celrep.2021.109399
  
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sciencedirect.com/science/article/pii/S221112472100797X
Jun 2021
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HepaCAM controls astrocyte self-organization and coupling

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1. scibot 25 Jun 2021
  
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  RRID:AB_2533914
  
  DOI: 10.1016/j.neuron.2021.05.025
  
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C9orf72 deficiency promotes microglial-mediated synaptic loss in aging and amyloid accumulation

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1. scibot 16 Jun 2021
  
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  DOI: 10.1016/j.neuron.2021.05.020
  
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Selective removal of astrocytic APOE4 strongly protects against tau-mediated neurodegeneration and decreases synaptic phagocytosis by microglia

1
1. scibot 09 Apr 2021
  
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  RRID:AB_2533914
  
  DOI: 10.1016/j.neuron.2021.03.024
  
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Generation of human pluripotent stem cell-derived fused organoids with oligodendroglia and myelin

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  DOI: 10.1016/j.xpro.2021.100443
  
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Jan 2021
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SEQUIN: An imaging and analysis platform for quantification and characterization of synaptic structures in mouse

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1. scibot 21 Jan 2021
  
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  DOI: 10.1016/j.xpro.2020.100268
  
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Cerebellospinal Neurons Regulate Motor Performance and Motor Learning

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1. scibot 26 Sep 2020
  
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  DOI: 10.1016/j.celrep.2020.107595
  
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SEQUIN Multiscale Imaging of Mammalian Central Synapses Reveals Loss of Synaptic Connectivity Resulting from Diffuse Traumatic Brain Injury

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1. scibot 13 Sep 2020
  
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  DOI: 10.1016/j.neuron.2020.04.012
  
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Spinal Wnt5a plays a key role in spinal dendritic spine remodeling in neuropathic and inflammatory pain models and in the pro-algesic effects of peripheral Wnt3a

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1. scibot 03 Sep 2020
  
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  rabbit anti-PSD-95
  
  DOI: 10.1523/JNEUROSCI.2942-19.2020
  
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Monosynaptic tracing maps brain-wide afferent oligodendrocyte precursor cell connectivity

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1. scibot 13 Jan 2020
  
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  DOI: 10.7554/eLife.49291
  
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Alzheimer's Disease Risk Factor Pyk2 Mediates Amyloid-β-Induced Synaptic Dysfunction and Loss

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  DOI: 10.1523/JNEUROSCI.1873-18.2018
  
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OLIG2 Drives Abnormal Neurodevelopmental Phenotypes in Human iPSC-Based Organoid and Chimeric Mouse Models of Down Syndrome

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  DOI: 10.1016/j.stem.2019.04.014
  
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sciencedirect.com/science/article/pii/S1934590919301638
Nov 2018
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Untitled document

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Astrocyte-Secreted Chordin-like 1 Drives Synapse Maturation and Limits Plasticity by Increasing Synaptic GluA2 AMPA Receptors

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1. scibot 05 Nov 2018
  
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Untitled document

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Astrocyte-Secreted Glypican 4 Regulates Release of Neuronal Pentraxin 1 from Axons to Induce Functional Synapse Formation

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ncbi.nlm.nih.gov/pmc/articles/PMC5672548/
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Speed and segmentation control mechanisms characterized in rhythmically-active circuits created from spinal neurons produced from genetically-tagged embryonic stem cells

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1. scibot 08 Nov 2017
  
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  AB_2533914
  
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