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  1. Last 7 days
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    Lithocholic acid binds TULP3 to activate sirtuins and AMPK to slow down ageing
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    Lithocholic acid phenocopies anti-ageing effects of calorie restriction
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    Generation of hiPSCs lines from three sporadic Parkinson’s disease patients
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    sciencedirect.com/science/article/pii/S1873506124003301
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    Protein tau phosphorylation in the proline rich region and its implication in the progression of Alzheimer's disease
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    sciencedirect.com/science/article/pii/S0014488624003753
  6. Dec 2024
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    Inhibiting intracellular CD28 in cancer cells enhances antitumor immunity and overcomes anti-PD-1 resistance via targeting PD-L1
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    Increased intrinsic membrane excitability is associated with olivary hypertrophy in spinocerebellar ataxia type 1
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    Impacts of APOE-ε4 and exercise training on brain microvascular endothelial cell barrier function and metabolism
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    1-s2.0-S2589004224027433-main-html.html
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    Mechano-dependent sorbitol accumulation supports biomolecular condensate
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  12. Nov 2024
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    Ethanol modulates astrocyte activation and neuroinflammation via miR-339/NLRP6 inflammasome signaling
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    Potassium ion channel modulation at cancer-neural interface enhances neuronal excitability in epileptogenic glioblastoma multiforme
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    Non-autophagic Golgi-LC3 lipidation facilitates TFE3 stress response against Golgi dysfunction
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  16. Sep 2024
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    Heterozygous cis HYDIN mutations cause primary ciliary dyskinesia
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    A living organoid biobank of patients with Crohn’s disease reveals molecular subtypes for personalized therapeutics
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    Drivers of Vessel Progenitor Fate Define Intermediate Mesoderm Dimensions by Inhibiting Kidney Progenitor Specification
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    CHCHD2 mutant mice display mitochondrial protein accumulation and disrupted energy metabolism
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    eIF2B localisation and its regulation during the integrated stress response is cell-type specific
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    gp78-regulated KAP1 phosphorylation induces radioresistance in breast cancer by facilitating PPP1CC/PPP2CA ubiquitination
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    “β-Hydroxybutyrate Recapitulates the Beneficial Effects of Ketogenic Metabolic Therapy in Polycystic Kidney Disease”
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    The Configuration of RPA, RAD51, and DMC1 Binding in Meiosis Reveals the Nature of Critical Recombination Intermediates
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    LRRK2 knockdown in zebrafish causes developmental defects, neuronal loss, and synuclein aggregation
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    Development of a 3-dimensional organotypic model with characteristics of peripheral sensory nerves
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    Dynamic remodeling of Septin structures fine-tunes myogenic differentiation
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    Introduction of an RS1 mutation causative variant consistent with identified XLRS patient using CRISPR/Cas9 technology in normal iPSC
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    Polyamines sustain epithelial regeneration in aged intestines by modulating protein homeostasis
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  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Trigeminal innervation and tactile responses in mouse tongue
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    Antibodies and complement are key drivers of thrombosis
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  32. Aug 2024
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    Generation of hereditary spastic paraplegia patient-derived induced pluripotent stem cell line UJSi003-A
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    Human-induced pluripotent stem cell–derived neural stem cell exosomes improve blood–brain barrier function after intracerebral hemorrhage by activating astrocytes via PI3K/AKT/MCP-1 axis
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    HLTF resolves G4s and promotes G4-induced replication fork slowing to maintain genome stability
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    Thyroid hormone suppresses medulloblastoma progression through promoting terminal differentiation of tumor cells
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    Characterization of an induced pluripotent stem cell line (NCHi013-A) from a 5-year-old male with pulmonary atresia with intact ventricular septum and a biventricular repair
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  38. www.frontiersin.org www.frontiersin.org
    Do extracellular vesicles have specific target cells?; Extracellular vesicle mediated embryo maternal communication
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      DOI: 10.3389/fmolb.2024.1415909

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    frontiersin.org/journals/molecular-biosciences/articles/10.3389/fmolb.2024.1415909/full
  39. www.pnas.org www.pnas.org
    FosGFP expression does not capture a sensory learning-related engram in superficial layers of mouse barrel cortex
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  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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  41. Jul 2024
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    MicroRNA-19b exacerbates systemic sclerosis through promoting Th9 cells
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  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Apocynin Prevents Cigarette Smoke-Induced Anxiety-Like Behavior and Preserves Microglial Profiles in Male Mice
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      DOI: 10.3390/antiox13070855

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  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of the main barriers to Ku accumulation in chromatin
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    Microglia rescue neurons from aggregate-induced neuronal dysfunction and death through tunneling nanotubes
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    Lack of mismatch repair enhances resistance to methylating agents for cells deficient in oxidative demethylation
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    Inhalation of hydrogen gas mitigates sevoflurane-induced neuronal apoptosis in the neonatal cortex and is associated with changes in protein phosphorylation
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    DOT1L/H3K79me2 represses HIV-1 reactivation via recruiting DCAF1
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    Respiratory infection with influenza A virus delays remyelination and alters oligodendrocyte metabolism
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    Affimer reagents enable targeted delivery of therapeutic agents and RNA via Virus-Like Particles
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    A high-throughput approach to identify BRCA1-downregulating compounds to enhance PARP inhibitor sensitivity
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    Construction of multilayered small intestine-like tissue by reproducing interstitial flow
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    Antibody-assisted selective isolation of Purkinje cell nuclei from mouse cerebellar tissue
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    A Combination of ß-Hydroxybutyrate and Citrate Ameliorates Disease Progression in a Rat Model of Polycystic Kidney Disease
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    Suppressed basal mitophagy drives cellular aging phenotypes that can be reversed by a p62-targeting small molecule
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    The role of JMJD2A in immune evasion and malignant behavior of esophageal squamous cell carcinoma
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    An atlas of human vector-borne microbe interactions reveals pathogenicity mechanisms
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    Thalamic activity-dependent specification of sensory input neurons in the developing chick entopallium
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    GABAergic neurons of anterior thalamic reticular nucleus regulate states of consciousness in propofol‐ and isoflurane‐mediated general anesthesia
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    Generation of iPSC line NCHi015-A from a patient with truncus arteriosus carrying heterozygous variants in KMT2D and NOTCH1
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  64. May 2024
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    Generation of an EYS-associated retinitis pigmentosa patient-derived human pluripotent stem cell line (MUi038-A)
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    The CD8+ T cell tolerance checkpoint triggers a distinct differentiation state defined by protein translation defects
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    Bidirectional regulation of levodopa-induced dyskinesia by a specific neural ensemble in globus pallidus external segment
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    Leucyl-tRNA synthetase contributes to muscle weakness through mTORC1 activation and autophagy suppression in a mouse model of Duchenne Muscular Dystrophy
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    Viral mimicry and memory deficits upon microglial deletion of ATRX
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    Effective cryopreservation of human brain tissue and neural organoids
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    Establishment of an induced pluripotent stem cell (iPSC) line (INNDSUi004-A) from a patient with Congenital Nemaline Myopathy
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  73. Apr 2024
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    Restoring thalamocortical circuit dysfunction by correcting HCN channelopathy in Shank3 mutant mice
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    Adipocyte-Released Adipomes in Chagas Cardiomyopathy: Impact on Cardiac Metabolic and Immune Regulation
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    Bovine placental extracellular vesicles carry the fusogenic syncytin BERV-K1
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    Growth hormone promotes the reconstruction of injured axons in the hypothalamo-neurohypophyseal system
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    DDX20 is required for cell-cycle reentry of prospermatogonia and establishment of spermatogonial stem cell pool during testicular development in mice
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    ptx3a+ fibroblast/epicardial cells provide a transient macrophage niche to promote heart regeneration
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    ITPRIPL1 binds CD3ε to impede T cell activation and enable tumor immune evasion
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    Osteopontin drives neuroinflammation and cell loss in MAPT-N279K frontotemporal dementia patient neurons
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    The autophagy inhibitor NSC185058 suppresses mTORC1-mediated protein anabolism in cultured skeletal muscle
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    Systematic HOIP interactome profiling reveals critical roles of linear ubiquitination in tissue homeostasis
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    Tumor cell-intrinsic epigenetic dysregulation shapes cancer-associated fibroblasts heterogeneity to metabolically support pancreatic cancer
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    Central inhibition of HDAC6 re-sensitizes leptin signaling during obesity to induce profound weight loss
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    Brucella-driven host N-glycome remodeling controls infection
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    Matrilin-3 supports neuroprotection in ischemic stroke by suppressing astrocyte-mediated neuroinflammation
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    Cortical brain organoid slices (cBOS) for the study of human neural cells in minimal networks
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    RhoA downregulation in the murine intestinal epithelium results in chronic Wnt activation and increased tumorigenesis
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    Establishment of an induced pluripotent stem cell (iPSC) line (INNDSUi005-A) from a healthy female Chinese Han
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    Adipose stem cells control obesity-induced T cell infiltration into adipose tissue
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    A novel GABAergic population in the medial vestibular nucleus maintains wakefulness and gates rapid eye movement sleep
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    Protocol to analyze Drosophila intestinal tumor cellular heterogeneity using immunofluorescence imaging and nuclear size quantification
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    Zebrafish as a model to investigate a biallelic gain-of-function variant in MSGN1, associated with a novel skeletal dysplasia syndrome
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    Mechanisms of HIV-Mediated Blood-Brain Barrier Compromise and Leukocyte Transmigration under the Current Antiretroviral Era.
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    Generation of an induced pluripotent stem cell line (PNUYHi002-A) from a patient with Alzheimer’s disease carrying PRNP M232R variant
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  99. Feb 2024
  100. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Upregulated α-actinin-1 impairs endometrial epithelial cell adhesion by downregulating NEBL in recurrent implantation failure
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  101. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Modeling the precise interaction of glioblastoma with human brain region-specific organoids
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    Evolutionary analysis identifies a Golgi pathway and correlates lineage-specific factors with endomembrane organelle emergence in apicomplexans
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    ASICs mediate fast excitatory synaptic transmission for tactile discrimination
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    Proline restores mitochondrial function and reverses aging hallmarks in senescent cells
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  105. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Parkinson’s Disease Risk Enhancers in Microglia
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  106. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Acetylation-induced proteasomal degradation of the activated glucocorticoid receptor limits hormonal signaling
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  107. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Deficient tRNA posttranscription modification dysregulated the mitochondrial quality controls and apoptosis
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    SMARCAL1 is a dual regulator of innate immune signaling and PD-L1 expression that promotes tumor immune evasion
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  109. Jan 2024
  110. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Merkel cells and keratinocytes in oral mucosa are activated by mechanical stimulation
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    Mesothelial cells with mesenchymal features enhance peritoneal dissemination by forming a protumorigenic microenvironment
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    Integration of reconfigurable microchannels into aligned three-dimensional neural networks for spatially controllable neuromodulation
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    Mechanosensitive hormone signaling promotes mammary progenitor expansion and breast cancer risk
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    Lipopolysaccharide-induced sepsis impairs M2R-GIRK signaling in the mouse sinoatrial node
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    DMHPpp1r17 neurons regulate aging and lifespan in mice through hypothalamic-adipose inter-tissue communication
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  116. Dec 2023
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    Autophagy supports PDGFRA-dependent brain tumor development by enhancing oncogenic signaling
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    B3GALT6 promotes dormant breast cancer cell survival and recurrence by enabling heparan sulfate-mediated FGF signaling
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    Disinhibition by VIP interneurons is orthogonal to cross-modal attentional modulation in primary visual cortex
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    Generation of induced pluripotent stem cell lines from a sister pair who suffered post-partum or recurrent Spontaneous Coronary Artery Dissections
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    Generation of a gene-corrected isogenic iPSC cell line from an X-linked retinoschisis patient with a hemizygous mutation c.304C > T (p.R102W) in RS1 gene
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  122. Nov 2023
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    PAK1-dependent mechanotransduction enables myofibroblast nuclear adaptation and chromatin organization during fibrosis
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    Comparative spatial proteomics of Plasmodium-infected erythrocytes
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  125. www.science.org www.science.org
    Dopamine error signal to actively cope with lack of expected reward
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  126. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Systemic and intrinsic functions of ATRX in glial cell fate and CNS myelination in male mice
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  127. journals.physiology.org journals.physiology.org
    2022 Cannon lecture: an ode to signal transduction: how the growth hormone pathway revealed insight into height, malignancy, and obesity
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  128. 52.53.155.43 52.53.155.43
    2022 Cannon Lecture: An ode to signal transduction - how the growth hormone pathway revealed insight into height, malignancy and obesity
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  129. www.biorxiv.org www.biorxiv.org
    Increased intrinsic membrane excitability is associated with hypertrophic olivary degeneration in spinocerebellar ataxia type 1
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    GABAergic-like dopamine synapses in the brain
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    KANK1 shapes focal adhesions by orchestrating protein binding, mechanical force sensing, and phase separation
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    Striatopallidal cannabinoid type-1 receptors mediate amphetamine-induced sensitization
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    The roles of the native cell differentiation program aberrantly recapitulated in Drosophila intestinal tumors
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    Addition of exogenous diacylglycerol enhances Wnt/β-catenin signaling through stimulation of macropinocytosis
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    Dental Pulp Stem Cells Accelerate Wound Healing through CCL2 induced M2 Macrophages Polarization
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  139. Sep 2023
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    Hyperglycemia-regulated tRNA-derived fragment tRF-3001a propels neurovascular dysfunction in diabetic mice
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    Targeting MCL-1 triggers DNA damage and an anti-proliferative response independent from apoptosis induction
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    Single-cell epigenome analysis identifies molecular events controlling direct conversion of human fibroblasts to pancreatic ductal-like cells
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    Age-Dependent Regulation of Dendritic Spine Density and Protein Expression in Mir324 KO Mice
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  146. Aug 2023
  147. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Age-dependent regulation of dendritic spine density and protein expression in Mir324 KO mice
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  148. dx.doi.org dx.doi.org
    Luteal Lipid Droplets: A Novel Platform for Steroid Synthesis
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    Interaction of an α-synuclein epitope with HLA-DRB1∗15:01 triggers enteric features in mice reminiscent of prodromal Parkinson’s disease
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  150. 52.53.155.43 52.53.155.43
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    Single-cell transcriptomic analysis of the identity and function of fibro/adipogenic progenitors in healthy and dystrophic muscle
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    Exosomal release of the virus-encoded chemokine receptor US28 contributes to chemokine scavenging
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  154. Jul 2023
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    Light-Responsive MicroRNA Molecules in Human Retinal Organoids are Differentially Regulated by Distinct Wavelengths of Light
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    Imbalance of helper T cell subtypes and adipokine secretion in perivascular adipose tissue as a trigger of atherosclerosis in chronic Porphyromonas gingivalis W83 infection
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    Creation of iPSC line NCHi004-A from a patient with Down syndrome and congenital heart defects
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    Generation of an induced pluripotent stem cell line (NCHi010-A) from a 6-year-old female with Down syndrome and without congenital heart disease
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    The RagA GTPase protects young egg chambers in Drosophila
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    Ablation of Projection Glutamatergic Neurons in the Lateral Cerebellar Nuclei Alters Motor Coordination in Vglut2-Cre+ Mice
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    Distinct myeloid population phenotypes dependent on TREM2 expression levels shape the pathology of traumatic versus demyelinating CNS disorders
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    Characterizing microglial senescence: Tau as a key player
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    Spinocerebellar Ataxia Type 1 Characteristics in Patient-Derived Fibroblast and iPSC-Derived Neuronal Cultures
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  169. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Characterization of Hofbauer cell polarization and VEGF localization in human term placenta from active and inactive pregnant individuals
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    Early chronic suppression of microglial p38α in a model of Alzheimer’s disease does not significantly alter amyloid-associated neuropathology
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    Lineage skewing and genome instability underlie marrow failure in a zebrafish model of GATA2 deficiency
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    Unexpected Kif4a functions in adult regeneration encompass a dual role in neurons and in proliferative repair Schwann cells
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  173. May 2023
  174. www.embopress.org www.embopress.org
    Phospholipid scramblase Xkr8 is required for developmental axon pruning via phosphatidylserine exposure
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    Corrigendum to “DOPA pheomelanin is increased in nigral neuromelanin of Parkinson’s disease” [Prog. Neurobiol. 223 (2023) 102414]
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    Normal pressure hydrocephalus decreases the proliferation of oligodendrocyte progenitor cells and the expression of CNPase and MOG proteins in the corpus callosum before behavioral deficits occur
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    Thrombospondin1 mimics rapidly relieve depression via Shank3 dependent uncoupling between dopamine D1 and D2 receptors
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    Generation of a PDGFRB-mCherry knock-in reporter human induced pluripotent stem cell line (KITi001-A-1), using CRISPR/Cas9 nuclease
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    Generation of a human induced pluripotent stem cell line (INEUi001-A) from an amyotrophic lateral sclerosis/frontotemporal dementia patient with a C9ORF72 G4C2 genotype of <2 (GGGGCCG) and 10 repeats
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    Bone marrow Adipoq-lineage progenitors are a major cellular source of M-CSF that dominates bone marrow macrophage development, osteoclastogenesis, and bone mass
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    TNIP1 inhibits selective autophagy via bipartite interaction with LC3/GABARAP and TAX1BP1
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    SARS-CoV-2 Spike Protein Downregulates Cell Surface α7nAChR through a Helical Motif in the Spike Neck
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    Characterization of the structure and control of the blood-nerve barrier identifies avenues for therapeutic delivery
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    Abl2 Kinase Differentially Regulates iGluRs Current Activity and Synaptic Localization
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    Regulation of RNA localization during oocyte maturation by dynamic RNA-ER association and remodeling of the ER
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    The oncogenic JAG1 intracellular domain is a transcriptional cofactor that acts in concert with DDX17/SMAD3/TGIF2
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    sciencedirect.com/science/article/pii/S1534580722007602
  221. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide survey of D/E repeats in human proteins uncovers their instability and aids in identifying their role in the chromatin regulator ATAD2
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    1. scibot 22 Nov 2022
      RRID:AB_2534079

      DOI: 10.1016/j.isci.2022.105464

      Resource: (Thermo Fisher Scientific Cat# A-11012, RRID:AB_2534079)

      Curator: @scibot

      SciCrunch record: RRID:AB_2534079

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      RRID:AB_2534079
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