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BAF60C links nucleolar stress to β cell dysfunction in type 2 diabetes through controlling Reg3b mRNA decay

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Modeling human prenatal adrenocortical functional zonation dynamics from pluripotent stem cells

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Metabolite-gated vascular contractility switch: OXGR1 activation mechanism enables agonist therapy for rosacea erythema

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AxoMetric platform facilitates rapid and unbiased automated quantification of axon regeneration in tissue sections

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Mar 2026
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Sex differences in corticotropin-releasing factor receptor-2α expressing neurons in acutely stressed mice

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A strategy of microglia replacement alleviates microgliopathy in a CSF1R I794T hotspot mutation mouse model of CSF1R-related disorder

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Generation of the induced pluripotent stem cell line BTHBIOi002-A derived from a USH2 patient with c.2512C>T and c.2802T>G mutations in USH2A gene

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Rapamycin Reduces Amyloid‐β Plaques and Improves Behavioral Performance in a Sex‐Dependent Manner in Mouse Models of Amyloidosis

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pmc.ncbi.nlm.nih.gov/articles/PMC12945924/
Feb 2026
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Deficiency of Pdap1 Results in Embryonic Lethality and Diminished Vascularization

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Generation and characterization of POMC-tdTomato reporter human pluripotent stem cell lines

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CXCR2 affects sensitization of radioresistant HPV-negative head and neck squamous cell carcinoma cells by ABT-263

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Minimizing far-extending chromatin perturbation in genome editing preserves stem cell identity

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Regulation of mitophagy by Fis1 and Fascin1-organized actin

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  DOI: 10.1016/j.cub.2026.01.062
  
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Nonsense-mediated mRNA decay orchestrates neuronal migration and cortical lamination while modulating Reelin and ciliary gene regulatory networks

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Vitamin B2 and B3 nutrigenomics reveals a therapy for NAXD disease

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  DOI: 10.1016/j.cell.2026.01.022
  
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Messenger RNA delivery to islet β cells using conjugated lipid nanoparticles

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  DOI: 10.1016/j.xcrm.2026.102634
  
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Distinct spatial patterning and transcriptomic landscapes of human neural organoids by localized delivery of morphogens

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1. scibot 24 Feb 2026
  
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  DOI: 10.1016/j.stem.2026.01.008
  
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More than microglial depletion: PLX5622 activates the hepatic constitutive androstane receptor to alter anesthesia and addiction

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1. scibot 24 Feb 2026
  
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  DOI: 10.1016/j.neuron.2025.12.044
  
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1-s2.0-S2352345X26000330-main-html.html

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1-s2.0-S2589004226004773-main-html.html

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Unveiling critical signaling pathways in the murine salivary gland and the role of midkine

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Global mapping of circRNA-target RNA interactions reveal P-body-mediated translational repression

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Insolubilome profiling defines molecular features that influence protein insolubility with aging

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Red blood cells serve as a primary glucose sink to improve glucose tolerance at altitude

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Single-cell multi-omic analyses highlight the essential role of NKX2.2-CLEC16A/endosomal pathway for human pancreatic differentiation and function

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Induction of neurodegeneration in the hippocampus of senescence-accelerated mouse-prone 8 (SAMP8) mice by blood-brain barrier-crossing serum amyloid P component

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  DOI: 10.1186/s12974-026-03704-7
  
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54.241.53.176 54.241.53.176

1-s2.0-S2589004226004530-main-html.html

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Deletion of Mfn2 in endothelial cells triggers a mitohormetic response that improves systemic metabolism and healthspan in mice

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  DOI: 10.1016/j.cmet.2026.01.012
  
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Cognitive rejuvenation through partial reprogramming of engram cells

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1. scibot 12 Feb 2026
  
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  DOI: 10.1016/j.neuron.2025.11.028
  
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A Plastic EMP1+ to LGR5+ Cell State Conversion as a Bypass to KRASG12D Pharmacologic Inhibition in Metastatic Colorectal Cancer

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  DOI: 10.1158/2159-8290.CD-25-0679
  
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Cleavage of mRNAs by a minority of pachytene piRNAs improves sperm fitness

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  DOI: 10.1038/s41586-026-10102-9
  
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nature.com/articles/s41586-026-10102-9
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Dorsoventral-mediated Shh induction is required for axolotl limb regeneration

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1. scibot 07 Feb 2026
  
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  DOI: 10.7554/eLife.106917
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12875611/
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A Common Iba1 Antibody Labels Vasopressin Neurons in Mice

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1. scibot 07 Feb 2026
  
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  DOI: 10.1523/ENEURO.0323-25.2025
  
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Patient-derived glioblastoma organoids as real-time avatars for assessing responses to clinical CAR-T cell therapy

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1. scibot 07 Feb 2026
  
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  DOI: 10.1016/j.stem.2024.11.010
  
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Converging dopamine pathways onto basolateral amygdala neurons encode exploration decisions

1
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  DOI: 10.1016/j.neuron.2025.12.007
  
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Selective adhesion preserves eye patterning as axonal retinotopy in the Drosophila brain

1
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Multi-omic analysis of guided and unguided forebrain organoids reveals differences in cellular composition and metabolic profiles

1
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  DOI: 10.1016/j.crmeth.2025.101295
  
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ATP7B-maintained copper stores in myeloid progenitors are required for functional maturation of neutrophils

1
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Selenoprotein P deletion ameliorates metabolic stress-associated anxiety-like behavior in male mice

1
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  DOI: 10.1210/endocr/bqag010
  
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Dynamic and differential renal cortical cell-specific mitochondrial metabolism in response to fasting

1
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  DOI: 10.1152/ajprenal.00235.2025
  
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52.53.155.43 52.53.155.43

2025.09.03.673267v1.full-html.html

1
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Jan 2026
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Injured epithelial cell states impact kidney allograft survival after T-cell-mediated rejection

1
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In vivo AGO-APP for cell-type- and compartment-specific miRNA profiling in the mouse brain

1
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NUSAP1 Recruits DAXX to Suppress HIF‐Driven Triple‐Negative Breast Cancer Progression

1
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MITF, TFEB, and TFE3 drive distinct adaptive gene expression programs and immune infiltration in melanoma

1
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Transsynaptic tracing techniques to interrogate neuronal connectivity of glioblastomas

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54.241.53.176 54.241.53.176

1-s2.0-S2589004226001161-main-html.html

1
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Tumor-associated macrophages enhance peripheral nerve tumor infiltration and spinal cord repair

1
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  DOI: 10.1016/j.immuni.2025.12.016
  
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NuMA promotes constitutive heterochromatin compaction by stabilizing linker histone H1 on chromatin

1
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  DOI: 10.1016/j.celrep.2025.116901
  
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Airway injury induces alveolar epithelial responses mediated by macrophages

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Neuropathic pain-like responses in a chronic CNS injury model are mediated by corticospinal-targeted spinal interneurons

1
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  DOI: 10.1523/JNEUROSCI.1264-24.2025
  
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Partial Deletion of Cxcl12 from Hippocampal Cajal–Retzius Cells Does Not Disrupt Dentate Gyrus Development or Neurobehaviors

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  DOI: 10.1523/ENEURO.0245-25.2025
  
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54.241.53.176 54.241.53.176

Optimization of oxygen concentration and glycosphingolipid effects on spermatogenesis in mouse testicular culture

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  DOI: 10.1093/biolre/ioaf284
  
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The UFL1-AKT positive feedback loop promotes breast cancer progression by enhancing lipid synthesis

1
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YAP/TAZ-VGLL3 governs adipocyte fate via epigenetic reprogramming of PPARγ and its target enhancers

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  DOI: 10.1126/sciadv.aea7235
  
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Targeting TCF21-TCF3 heterodimer in tumor-associated pericytes attenuates hematogenous metastasis by restoring pericyte gatekeeper function

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54.241.53.176 54.241.53.176

1-s2.0-S2589004226000933-main-html.html

1
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Inducible deletion of DGAT1 and 2 from microglia exacerbates neurodegeneration and endolysosomal lipid accumulation in male PS19 mice

1
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Optimized selection of specific antibodies against rodent ESR1 proteins and their application for immunohistochemistry and dual immunohistofluorescence with the specific anti-ESR2 antibody PPZ0506

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Mapping the Tissue‐of‐Origins of Mesenchymal Stromal Cells in Injury Repair

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54.241.53.176 54.241.53.176

2026.01.05.697593v1.full-html.html

1
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  DOI: 10.64898/2026.01.05.697593
  
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54.241.53.176 54.241.53.176

2026.01.07.694713v1.full-html.html

1
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Activation of a branched-chain amino acid rheostat restores replication-dependent hematopoietic stem cell fitness

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  DOI: 10.1016/j.stem.2025.12.018
  
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1-s2.0-S2589004226000696-main-html.html

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  DOI: 10.1016/j.isci.2026.114694
  
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Microenvironmental TGF-β is an early driver of NF1-associated tumor formation

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  DOI: 10.1016/j.celrep.2025.116822
  
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Tissue-specific restriction of transposon-derived regulatory elements safeguards cell-type identity

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Aberrant calcium signaling and neuronal activity in the L271H CACNA1D (Cav1.3) iPSC model of neurodevelopmental disease

3
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  DOI: 10.1038/s41380-025-03429-8
  
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Plasticity of synapses innervating spinal motor neurons after spinal cord injury in rhesus monkeys

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Retinal ganglion cell survival and functional maturation in transiently vascularized human retinal organoids

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Generation of RB1 knockout human embryonic stem cell lines derived from H9 using CRISPR/Cas9

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Tachykinin signaling defines distinct populations of glia in the enteric nervous system

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State-specific enhancer landscapes govern microglial plasticity

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Rothia mucilaginosa membrane vesicles stabilize labile iron to alleviate UVB-induced ferroptosis

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The Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Modulates the Functional Output of Human Taste Bud Cells

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Assessing the barrier function of the retinal pigment epithelium in adult mice using transepithelial electrical resistance measurements and quantitative immunohistochemistry

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Dec 2025
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Neurexin regulates mechanical nociceptive sensitization by central inhibition in Drosophila

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3D post-implantation co-culture of human embryo and endometrium

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Establishment of six human induced pluripotent stem cell lines from healthy Central Asian donors (IPBi115-A, IPBi116-A, IPBi117-A, IPBi119-A, IPBi124-A, and IPBi129-A)

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Muscle satellite cell editing by LNP-CRISPR-Cas9 to resist muscle injury

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Modeling human embryo implantation in vitro

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2025.12.08.693069.full-html.html

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Histamine H3 Receptor Antagonist, Thioperamide, Improves Behavioral and Neuropathological Changes Associated with Subclinical Hypersensitivity to a Cow’s Milk Allergen

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Positioning and reversible suppression of CCR7+ dendritic cells in perivascular tumor niches shape cancer immunity

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Electroacupuncture suppresses premature ventricular complexes occurring post-myocardial infarction through corticothalamic circuit

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Biogenesis and migration of the sperm cytoplasmic droplet require ARRDC5 and TEX38

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Intravital observation of neuronal and immune cell dynamics in the developing mammalian brain

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Protocol for generation of endothelial cells from human-derived iPSCs and integration into mouse brain explants

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1-s2.0-S2589004225026860-main-html.html

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Locus coeruleus microcircuitry processes periaqueductal gray inputs into distinct outputs for regulation of pain and anxiety

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MeCP2 regulates telencephalic development in human cerebral organoids

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The exit of naive pluripotency contains a metabolism-induced checkpoint for telomere homeostasis

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A fin-loop-like structure in GPX4 underlies neuroprotection from ferroptosis

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Astrocytic Interleukin-33 Deficiency Reduces Glial Fibrillary Acidic Protein Expression and Exacerbates Microglial Activation and Neuronal Damage in a Chemically Induced Inflamed Frontal Cortex

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Sensitized mast cells for targeted drug delivery and augmented cancer immunotherapy

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Context-dependent inhibitory roles of RhoA in 3D invasive cell migration within the extracellular matrix

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Jub-induced phosphorylation of Warts inhibits its activity and recruitment into biomolecular condensates

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Toggle-Untoggle – a cell segmentation tool with an interactive user verification interface

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BPS Publications

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Graded Hair Cell Ablation Reveals Functional Redundancy in the Mature Mouse Vestibular System

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Spatial Myeloid Landscape of Large Artery Atherosclerotic and Cardioembolic Thrombi Retrieved by Mechanical Thrombectomy

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A bacterial toxin as a novel anti-cancer drug modulating the tumor-microenvironment

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Excessive vigorous exercise impairs cognitive function through a muscle-derived mitochondrial pretender

1
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Cryptococcus exploits delayed microglial activation, and microglial osteopontin/Spp1 impairs peripheral host control

1
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  DOI: 10.1016/j.chom.2025.11.008
  
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Dual role of Oct4 and Sox2 in controlling the developmental capacity and timing of tissue morphogenesis in the embryonic lineage

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1. scibot 03 Dec 2025
  
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  DOI: 10.1016/j.devcel.2025.11.003
  
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Orexinergic lateral hypothalamus-anterior cingulate cortex circuit alleviates chronic stress-induced anxiety-like behaviors

1
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  DOI: 10.1016/j.cub.2025.10.083
  
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Hierarchical regulation of cerebellar neurogenesis by Sin3A-mediated gene repression

1
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  DOI: 10.1101/2025.10.17.683101
  
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Developmental CA2 perineuronal net reduction restores social memory in Shank3B KO mice

1
1. scibot 27 Nov 2025
  
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Jun N-terminal kinase's role in neuropathic pain: C-fiber remodeling and growth-associated protein-43 phosphorylation

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2025.11.16.688689v1.full-html.html

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  AB_2535792
  
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C5aR1+ microglia exacerbate neuroinflammation and cerebral edema in acute brain injury

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  DOI: 10.1016/j.neuron.2025.10.022
  
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Phenotype specific nuclear lamina remodeling in hiPSC derived cardiomyocytes bearing TNNT2 sarcomeric variants

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Inhibitory inputs from thalamus promote resilient spiking in tail of striatum

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Variability vs. phenotype: Multimodal analysis of Dravet syndrome brain organoids powered by deep learning

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ERK activation dynamics in maturing oocyte controls embryonic nuclear divisions in Caenorhabditis elegans

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  DOI: 10.1016/j.celrep.2024.115157
  
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NLRP3 inflammasome-dependent and -independent interleukin-1β release by macrophages exposed to wear and corrosion products from CoCrMo implants

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Modeling antithymocyte globulin-induced microvasculopathy using human iPSC-derived vascularized liver organoids

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  DOI: 10.1016/j.xcrm.2025.102433
  
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Regulatory T cell stability determines the efficiency of bile duct regeneration during cholangitis

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2025.11.11.687663v1.full-html.html

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  RRID:AB_253579
  
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Hypertension-induced neurovascular and cognitive dysfunction at single-cell resolution

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  DOI: 10.1016/j.neuron.2025.10.018
  
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Cortical organoid-derived models of the melanoma brain metastatic niche enable prioritization of cancer-targeting drugs

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  DOI: 10.1016/j.crmeth.2025.101236
  
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Thermoresponsive motor behavior is mediated by ring neuron circuits in the central complex of Drosophila

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2025.11.05.686656v1.full-html.html

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Nuclear-lamin-guided plastic positioning and folding of the human genome

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A phenotypic brain organoid atlas and biobank for neurodevelopmental disorders

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A myeloid Tet2-IL-1β axis modulates intestinal inflammation by restricting catecholaminergic stimulation of enterochromaffin cell differentiation

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  DOI: 10.1016/j.immuni.2025.10.012
  
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Cystine import and oxidative catabolism fuel vascular growth and repair via nutrient-responsive histone acetylation

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A heterozygous USB1 variant linked to immunodeficiency

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  DOI: 10.70962/jhi.20250110
  
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N6-methyladenosine on L1PA governs the trans-silencing of LTRs and restrains totipotency in naive human embryonic stem cells

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The E3 ligase RNF32 controls the IκB kinase complex and NF-κB signaling in intestinal stem cells

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  DOI: 10.1016/j.molcel.2025.10.005
  
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3D-generation of high-purity midbrain dopaminergic progenitors and lineage-guided refinement of grafts supports Parkinson’s disease cell therapy

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Human heart-macrophage assembloids mimic immune-cardiac interactions and enable arrhythmia disease modeling

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Enhanced hybridization-proximity labeling discovers protein interactomes of single RNA molecules

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  DOI: 10.1038/s41467-025-64282-5
  
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Cholinergic interneurons of the dorsomedial striatum mediate winner-loser effects on social hierarchy dynamics in male mice

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  DOI: 10.1016/j.isci.2025.113581
  
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Microglial NLRP3 inflammasome activation leads to perineuronal net loss in cocultured neurons

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  DOI: 10.1007/s11033-025-11145-3
  
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The gain-of-function TREM2-T96K mutation increases risk for Alzheimer’s disease by impairing microglial function

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  DOI: 10.1016/j.neuron.2025.09.032
  
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Optogenetic stimulation of midbrain dopaminergic neurons rescues hippocampal synaptic plasticity deficits in a mouse model of Alzheimer’s disease

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  DOI: 10.1038/s41398-025-03588-w
  
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Midbrain degeneration triggers astrocyte reactivity and tau pathology in experimental Alzheimer’s Disease

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Vitamin C conveys geroprotection on primate ovaries

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Characterization of the dual functions of Leishmania CK1.2 in both the parasite and the macrophage using integrated proteomics and spatial mapping

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Integrated omics reveals disease-associated radial glia-like cells with epigenetically dysregulated interferon response in multiple sclerosis

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The p75 neurotrophin receptor controls the skeletal stem cell niche through sensory innervation

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Machine-learning-guided discovery of SLC25A45 as a mediator of mitochondrial methylated amino acid import and carnitine synthesis

1
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Generation and validation of a iPSC line from a healthy female donor using integration-free Sendai virus reprogramming

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Rac1 inhibition prevents axonal cytoskeleton dysfunction in transthyretin amyloid polyneuropathy

1
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Time-restricted feeding provides limited microglial immunometabolic improvements in diet-induced obese rats

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Diet gel-based oral drug delivery system for controlled dosing of small molecules for microglia depletion and inducible Cre recombination in mice

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Matrix-associated extracellular vesicles modulate human smooth muscle cell adhesion and directionality by presenting collagen VI

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Isoformic PD-1 impedes B cell activation and function in HIV-1 infection

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Capicua Refines Mossy Fiber–CA3 Axon Targeting in the Late Postnatal Hippocampus

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Maternal CENP-C restores centromere symmetry in mammalian zygotes to ensure proper chromosome segregation

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Liver-breast communication of adipocyte-oriented exosomes drives primary mammary cancer progression

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Transdifferentiation of endothelial progenitor cells into rhabdomyosarcoma defined by hedgehog signaling competence

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Hepatic acetyl-CoA metabolism modulates neuroinflammation and depression susceptibility via acetate

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Generation of a Flattop-T2A-H2B-Venus x C-peptide-mCherry double reporter human iPSC line to monitor WNT/Planar cell polarity pathway activity

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Reproducibility of PD patient-specific midbrain organoid data for in vitro disease modeling

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Seipin Governs caveolin-1 trafficking through modulating sphingolipid-glycerolipid balance

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Projection from the parafascicular nucleus of the thalamus to the insular cortex mediate analgesia and anti-anxiety behaviors in mice

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Tumor suppressor protein p53 governs human trophoblast lineage development

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Infectious bacteria, but not the microbiota, induce a NOX-ATM-cytokine pathway that controls epithelial turnover

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Functionally Essential and Structurally Diverse: Insights into the zebrafish Left-Right Organizer’s Cilia via Optogenetic IFT88 Perturbation and Volume Electron Microscopy

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Copper overload worsens the inflammatory response of microglia to amyloid beta (Aβ) by impairing phagocytosis and promoting mitochondrial DNA-mediated NLRP3 inflammasome activation

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Creeping fat-derived mechanosensitive fibroblasts drive intestinal fibrosis in Crohn’s disease strictures

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Corticotropin-releasing hormone signaling from piriform cortex to amygdala mediates social homophily in opioid addiction

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Cardiac mural cells are rate-limiting for coronary vascularization after heart injury

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Targeting glucose-inhibited hippocampal CCK interneurons prevents cognitive impairment in diet-induced obesity

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1-s2.0-S2589004225017973-main-html.html

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Environmental and genetic risk factors of depression converge on neuronal dysfunction driven by changes in cholesterol homeostasis

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Combinatorial BMP4 and activin direct the choice between alternate routes to endoderm in a stem cell model of human gastrulation

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Chemotherapy modulation by a cancer-associated microbiota metabolite

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Cyclin-dependent kinase inhibitor 1A mediates mouse line- and fate-dependent cellular responses in Cx3cr1-Cre genetic tools

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Coordination of autophagosome closure and release by the Alzheimer’s disease-associated protein BIN1

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2025.09.03.673267v1.full-html.html

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2025.08.29.673171v1.full-html.html

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Neural basis of transcutaneous electrical nerve stimulation for neuropathic pain relief

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Microbiota metabolite taurodeoxycholic acid maintains intestinal tissue residency of innate lymphoid cells via engagement with P2Y10 receptor

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Developmental Trajectories Predict Dendritic Remodeling After Injury

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Chemogenetic tuning reveals optimal MAPK signaling for cell-fate programming

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2025.08.22.671484v1.full-html.html

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Generation of human induced pluripotent stem cell lines from healthy Korean donors (IPBi101-A, IPBi102-A, IPBi103-A, IPBi105-A, IPBi107-A, IPBi108-A, IPBi110-A, IPBi111-A, IPBi113-A, and IPBi114-A)

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  DOI: 10.1016/j.scr.2025.103821
  
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Mitochondrial dysfunction reveals H2S-mediated synaptic sulfhydration as a potential mechanism for autism-associated social defects

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Temporal control of eating and body weight by GHSR-expressing suprachiasmatic nucleus neurons

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2025.08.28.672006v1.full-html.html

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Preventing CpG hypermethylation in oocytes safeguards mouse development

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An inducible model of human post-implantation development derived from primed and naive stem cells

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Nephronectin mediates the interaction between hair follicle epithelial progenitors and dermal stem cells and is involved in hair cycle progression

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Hepatocyte metabolic adaptations during pregnancy and lactation

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Long-range deployment of tumor-antigen-specific cytotoxic T lymphocytes inhibits lung metastasis of breast cancer

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A mouse organoid platform for modeling cerebral cortex development and cis-regulatory evolution in vitro

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Microbiota metabolite taurodeoxycholic acid maintains intestinal tissue residency of innate lymphoid cells via engagement with P2Y10 receptor

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lanz-et-al-hdac6-dependent-deacetylation-of-sae2-enhances-sumo1-conjugation-for-mitotic-integrity-html.html

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Protocol for assessing auditory function, cochlear synaptopathy, and afferent terminal morphology in laboratory mice

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Generation of patient-derived and gene-corrected hiPSC lines from Hereditary Hemorrhagic Telangiectasia type 2 patients with ACVRL1 c.1042delG mutation

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Investigating morphogen and patterning dynamics with optogenetic control of morphogen production

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Crossing nerve transfer restores limb movement by reorganizing the cortico-rubro-spinal pathway in peripheral nerve injury

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Astrocytes in the medial entorhinal cortex are required for spatial exploration

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A consensus definition for deep layer 6 excitatory neurons in mouse somatosensory, visual, and motor cortex

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