Hypothesis

170 Matching Annotations

Aug 2025
52.53.155.43 52.53.155.43

lanz-et-al-hdac6-dependent-deacetylation-of-sae2-enhances-sumo1-conjugation-for-mitotic-integrity-html.html

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1. scibot 27 Aug 2025
  
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  AB_2535855
  
  DOI: 10.1038/s44318-025-00532-y
  
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52.53.155.43/6a103bea7fec410145761c98221dd634cac35636/lanz-et-al-hdac6-dependent-deacetylation-of-sae2-enhances-sumo1-conjugation-for-mitotic-integrity-html.html
www.mdpi.com www.mdpi.com

Aquaporins in the Capillaries of the Dura Mater of Pigs

1
1. scibot 13 Aug 2025
  
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  DOI: 10.3390/ijms26157653
  
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mdpi.com/1422-0067/26/15/7653
52.53.155.43 52.53.155.43

1-s2.0-S2589004225010338-main-html.html

1
1. scibot 12 Aug 2025
  
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  RRID:AB_2535855
  
  DOI: 10.1016/j.isci.2025.112772
  
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52.53.155.43/8b0897d2d35a8ab9ab351db77e0eeb32b8358112/1-s2.0-S2589004225010338-main-html.html
Jul 2025
www.sciencedirect.com www.sciencedirect.com

Forebrain assembloids support the development of fast-spiking human PVALB+ cortical interneurons and uncover schizophrenia-associated defects

1
1. scibot 22 Jul 2025
  
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  DOI: 10.1016/j.neuron.2025.06.017
  
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sciencedirect.com/science/article/pii/S0896627325004751
www.cell.com www.cell.com

TIM3+ breast cancer cells license immune evasion during micrometastasis outbreak

1
1. scibot 15 Jul 2025
  
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  DOI: 10.1016/j.ccell.2025.06.015
  
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cell.com/cancer-cell/abstract/S1535-6108(25)00265-X
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Cloche/Npas4l is a pro-regenerative platelet factor during zebrafish heart regeneration

1
1. scibot 02 Jul 2025
  
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  DOI: 10.1016/j.devcel.2025.06.015
  
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sciencedirect.com/science/article/pii/S1534580725003703
Jun 2025
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Lymph node fibroblast phenotypes and immune crosstalk regulated by podoplanin activity

1
1. scibot 28 Jun 2025
  
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  DOI: 10.1016/j.celrep.2025.115908
  
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sciencedirect.com/science/article/pii/S2211124725006795
journals.physiology.org journals.physiology.org

Vascular protection by young circulating extracellular vesicles ameliorates aging-related pulmonary fibrosis | American Journal of Physiology-Cell Physiology | American Physiological Society

1
1. scibot 26 Jun 2025
  
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  RRID:AB_2535855
  
  DOI: 10.1152/ajpcell.00022.2025
  
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journals.physiology.org/doi/full/10.1152/ajpcell.00022.2025
journals.physiology.org journals.physiology.org

Vascular protection by young circulating extracellular vesicles ameliorates aging-related pulmonary fibrosis

1
1. scibot 26 Jun 2025
  
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  DOI: 10.1152/ajpcell.00022.2025
  
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journals.physiology.org/doi/10.1152/ajpcell.00022.2025
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The IL-33/ST2 axis and tissue Treg maintain epithelial homeostasis and restrain cancer development in the skin

1
1. scibot 17 Jun 2025
  
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  DOI: 10.1016/j.celrep.2025.115837
  
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sciencedirect.com/science/article/pii/S2211124725006084
52.53.155.43 52.53.155.43

Deficiency of estrogen receptor 2 expression enhances disorganization of the mouse uterus with age

1
1. scibot 13 Jun 2025
  
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  RRID:AB_2535855
  
  DOI: 10.1210/endocr/bqaf103
  
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52.53.155.43/292aa1ab21b4d9b718176cf4769577fc3b24ebfd/bqaf103-html.html
May 2025
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MePCE promotes homologous recombination through coordinating R-loop resolution at DNA double-stranded breaks

1
1. scibot 29 May 2025
  
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  DOI: 10.1016/j.celrep.2025.115740
  
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sciencedirect.com/science/article/pii/S221112472500511X
elifesciences.org elifesciences.org

Microglia aging in the hippocampus advances through intermediate states that drive activation and cognitive decline

1
1. scibot 22 May 2025
  
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  RRID:AB_2535855
  
  DOI: 10.7554/eLife.97671
  
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elifesciences.org/articles/97671
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Repetitive prefrontal tDCS activates VTA dopaminergic neurons, resulting in attenuation of Alzheimer’s Disease-like deficits in Tg2576 mice

1
1. scibot 21 May 2025
  
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  RRID:AB_2535855
  
  DOI: 10.1186/s13195-025-01736-4
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12039073/
Apr 2025
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Early A-synuclein aggregation decreases corticostriatal glutamate drive and synapse density

1
1. scibot 17 Apr 2025
  
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  DOI: 10.1016/j.nbd.2025.106918
  
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sciencedirect.com/science/article/pii/S0969996125001342
Mar 2025
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Protocol for generating human cerebral organoids from two-dimensional cultures of pluripotent stem cells bypassing embryoid body aggregation

1
1. scibot 14 Mar 2025
  
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  RRID:AB_2535855
  
  DOI: 10.1016/j.xpro.2025.103678
  
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sciencedirect.com/science/article/pii/S266616672500084X
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BMP-dependent patterning of ectoderm tissue material properties modulates lateral mesendoderm cell migration during early zebrafish gastrulation

1
1. scibot 11 Mar 2025
  
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  RRID:AB_2535855
  
  DOI: 10.1016/j.celrep.2025.115387
  
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sciencedirect.com/science/article/pii/S2211124725001585
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DA-DRD5 signaling reprograms B cells to promote CD8+ T cell-mediated antitumor immunity

1
1. scibot 04 Mar 2025
  
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  RRID:AB_2535855
  
  DOI: 10.1016/j.celrep.2025.115364
  
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sciencedirect.com/science/article/pii/S2211124725001354
Dec 2024
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Hormone-responsive progenitors have a unique identity and exhibit high motility during mammary morphogenesis

1
1. scibot 19 Dec 2024
  
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  DOI: 10.1016/j.celrep.2024.115073
  
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sciencedirect.com/science/article/pii/S2211124724014244
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Molecular tag for promoting N-glycan maturation in the cargo receptor-mediated secretion pathway

1
1. scibot 14 Dec 2024
  
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  DOI: 10.1016/j.isci.2024.111457
  
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sciencedirect.com/science/article/pii/S2589004224026841
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Chemotherapy induces myeloid-driven spatially confined T cell exhaustion in ovarian cancer

1
1. scibot 10 Dec 2024
  
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  DOI: 10.1016/j.ccell.2024.11.005
  
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sciencedirect.com/science/article/pii/S1535610824004409
Oct 2024
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Stem cell-specific ecdysone signaling regulates the development of dorsal fan-shaped body neurons and sleep homeostasis

1
1. scibot 09 Oct 2024
  
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  RRID:AB_2535855
  
  DOI: 10.1016/j.cub.2024.09.020
  
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sciencedirect.com/science/article/pii/S0960982224012314
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

CCL28 modulates neutrophil responses during infection with mucosal pathogens

1
1. scibot 04 Oct 2024
  
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  RRID:AB_2535855
  
  DOI: 10.7554/eLife.78206
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11444682/
Sep 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

ADARp150 counteracts whole genome duplication

1
1. scibot 26 Sep 2024
  
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  RRID:AB_2535855
  
  DOI: 10.1093/nar/gkae700
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11417406/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Protocol for in vivo CRISPR screening targeting murine testicular cells

1
1. scibot 16 Sep 2024
  
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  AB_2535855
  
  DOI: 10.1016/j.xpro.2024.103306
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11416641/
Aug 2024
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Thyroid hormone remodels cortex to coordinate body-wide metabolism and exploration

1
1. scibot 23 Aug 2024
  
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  AB_2535855
  
  DOI: 10.1016/j.cell.2024.07.041
  
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sciencedirect.com/science/article/pii/S0092867424008353
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The tyrosine phosphatases LAR and PTPRδ act as receptors of the nidogen-tetanus toxin complex

1
1. scibot 22 Aug 2024
  
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  AB_2535855
  
  DOI: 10.1038/s44318-024-00164-8
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11329502/
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Non-canonical autophosphorylation of RIPK1 drives timely pyroptosis to control Yersinia infection

1
1. scibot 22 Aug 2024
  
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  DOI: 10.1016/j.celrep.2024.114641
  
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sciencedirect.com/science/article/pii/S2211124724009914
link.springer.com link.springer.com

Steroid hormones and human choriogonadotropin influence the distribution of alpha6-integrin and desmoplakin 1 in gland-like endometrial epithelial spheroids

1
1. scibot 02 Aug 2024
  
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  Alexa Fluor 555 anti-rat
  
  DOI: 10.1007/s00418-020-01960-z
  
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link.springer.com/article/10.1007/s00418-020-01960-z/tables/2
www.science.org www.science.org

The acetyltransferase KAT7 is required for thymic epithelial cell expansion, expression of AIRE target genes, and thymic tolerance

1
1. scibot 02 Aug 2024
  
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  DOI: 10.1126/sciimmunol.abb6032
  
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science.org/doi/10.1126/sciimmunol.abb6032
Jul 2024
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FilamentID reveals the composition and function of metabolic enzyme polymers during gametogenesis

1
1. scibot 24 Jul 2024
  
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  RRID:AB_2535855
  
  DOI: 10.1016/j.cell.2024.04.026
  
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sciencedirect.com/science/article/pii/S0092867424004525
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G2 arrest primes hematopoietic stem cells for megakaryopoiesis

1
1. scibot 23 Jul 2024
  
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  AB_2535855
  
  DOI: 10.1016/j.celrep.2024.114388
  
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sciencedirect.com/science/article/pii/S2211124724007162
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Aging Differentially Affects Axonal Autophagosome Formation and Maturation

1
1. scibot 20 Jul 2024
  
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  RRID:AB_2535855
  
  DOI: 10.1080/15548627.2023.2236485
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10621248/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Complex representation of taste quality by second-order gustatory neurons in Drosophila

1
1. scibot 14 Jul 2024
  
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  DOI: 10.1016/j.cub.2022.07.048
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9474709/
www.embopress.org www.embopress.org

The tyrosine phosphatases LAR and PTPRδ act as receptors of the nidogen-tetanus toxin complex

2
1. scibot 12 Jul 2024
  
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  AB_2535855
  
  DOI: 10.1038/s44318-024-00164-8
  
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  RRID:AB_2535855
2. scibot 12 Jul 2024
  
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  AB_2535855
  
  DOI: 10.1038/s44318-024-00164-8
  
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Anhedonic behaviour in a TLR7-driven neuroinflammation mouse model is associated with impaired thalamostriatal signalling and immune cell ingress into the brain

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Acetyl-NPKY of Integrin-beta 1 binds KINDLIN2 to control endothelial cell proliferation and junctional integrity.

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Tumor cells impair immunological synapse formation via central nervous system-enriched metabolite

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Remodeling ceramide homeostasis promotes functional maturation of human pluripotent stem cell-derived β cells

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CCR2+ monocytes replenish border-associated macrophages in the diseased mouse brain

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Reprogramming fibroblast into human iBlastoids

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Microglia aging in the hippocampus advances through intermediate states that drive inflammatory activation and cognitive decline

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The Legionella pneumophila effector DenR hijacks the host NRas proto-oncoprotein to downregulate MAPK signaling

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The endogenous calpain inhibitor calpastatin attenuates axon degeneration in murine Guillain‐Barré syndrome

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Prostaglandin D2 synthase controls Schwann cells metabolism

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A humoral stress response protects Drosophila tissues from antimicrobial peptides

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In vivo CRISPR screening directly targeting testicular cells

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Akt3 activation by R-Ras in an endothelial cell enforces quiescence and barrier stability of neighboring endothelial cells via Jagged1

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NGFR regulates stromal cell activation in germinal centers

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Human conjunctiva organoids to study ocular surface homeostasis and disease

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Cytoneme signaling provides essential contributions to mammalian tissue patterning

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Golgi-to-ER retrograde transport prevents premature differentiation of Drosophila type II neuroblasts via Notch-signal-sending daughter cells

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Sbp2l contributes to oligodendrocyte maturation through translational control in Tcf7l2 signaling

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Histone methylation mediated by NSD1 is required for the establishment and maintenance of neuronal identities

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Microbial-dependent recruitment of immature myeloid cells promotes intestinal regeneration.

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A single cell genomics atlas of the Drosophila larval eye reveals distinct photoreceptor developmental timelines

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Replication stress and defective checkpoints make fallopian tube epithelial cells putative drivers of high-grade serous ovarian cancer

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Aging spinal cord microglia become phenotypically heterogeneous and preferentially target motor neurons and their synapses

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Machine learning identifies experimental brain metastasis subtypes based on their influence on neural circuits

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PIIS2211124723009543-html.html

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Jul 2023
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A cortico-amygdala neural substrate for endocannabinoid modulation of fear extinction

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Defective neurite elongation and branching in Nibp/Trappc9 deficient zebrafish and mice

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Sequential inhibitory plasticities in hippocampal area CA2 and social memory formation

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Replication stress impairs chromosome segregation and preimplantation development in human embryos

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A Single Cell Genomics Atlas of the Drosophila Larval Eye Reveals Distinct Developmental Timelines and Novel Markers for All Photoreceptor Subtypes

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Nuclease activity of Plasmodium falciparum Alba family protein PfAlba3

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Hippo pathway and Bonus control developmental cell fate decisions in the Drosophila eye

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Apoptotic cell fragments locally activate tingible body macrophages in the germinal center

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Axolemmal nanoruptures arising from paranodal membrane injury induce secondary axon degeneration in murine Guillain-Barré syndrome

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Natural variation in gene expression and viral susceptibility revealed by neural progenitor cell villages

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SSRN-id4261555-html.html

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Safeguarding Drosophila female germ cell identity depends on an H3K9me3 mini domain guided by a ZAD zinc finger protein

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Table 1 Antibodies and dyes compatible with mLSR-3D

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Atg1 modulates mitochondrial dynamics to promote germline stem cell maintenance in Drosophila

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POLθ processes ssDNA gaps and promotes replication fork progression in BRCA1-deficient cells

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Induced pluripotent stem cells and cerebral organoids from the critically endangered Sumatran rhinoceros

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Vps37a regulates hepatic glucose production by controlling glucagon receptor localization to endosomes

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Differential plasticity and fate of brain-resident and recruited macrophages during the onset and resolution of neuroinflammation

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Competition for endothelial cell polarity drives vascular morphogenesis in the mouse retina

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Dopamine activates astrocytes in prefrontal cortex via α1-adrenergic receptors

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Human-specific ARHGAP11B ensures human-like basal progenitor levels in hominid cerebral organoids

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Excitatory SST neurons in the medial paralemniscal nucleus control repetitive self-grooming and encode reward

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PTP1B is an intracellular checkpoint that limits T cell and CAR T cell anti-tumor immunity

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Mfsd2b and Spns2 are essential for maintenance of blood vessels during development and in anaphylactic shock

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Complex representation of taste quality by second-order gustatory neurons in Drosophila

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Jul 2022
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158524.1-20220614093707-covered-e0fd13ba177f913fd3156f593ead4cfd-html.html

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Jun 2022
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Nitric oxide improves regeneration and prevents calcification in bio-hybrid vascular grafts via regulation of vascular stem/progenitor cells

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Real time imaging of intra-axonal calcium flux in an explant mouse model of axonal Guillain-Barré syndrome

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MDM2 binds and ubiquitinates PARP1 to enhance DNA replication fork progression

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The ER ladder is a unique morphological feature of developing mammalian axons

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A plasma membrane-localized polycystin-1/polycystin-2 complex in endothelial cells elicits vasodilation

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Setd2 determines distinct properties of intestinal ILC3 subsets to regulate intestinal immunity

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Glucagon-Like Peptide-2 Stimulates S-Phase Entry of Intestinal Lgr5+ Stem Cells

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A genetic compensatory mechanism regulated by Jun and Mef2d modulates the expression of distinct class IIa Hdacs to ensure peripheral nerve myelination and repair

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Developmental single-cell transcriptomics of hypothalamic POMC neurons reveal the genetic trajectories of multiple neuropeptidergic phenotypes

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Fine-tuning of β-catenin in mouse thymic epithelial cells is required for postnatal T-cell development

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Myelinating Schwann cells and Netrin-1 control intra-nervous vascularization of the developing mouse sciatic nerve

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Dec 2021
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Persistent coxsackievirus B1 infection triggers extensive changes in the transcriptome of human pancreatic ductal cells

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Non-canonical protease-activated receptor 1 regulates lymphatic differentiation in zebrafish

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IL-1beta promotes the age-associated decline of beta cell function

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Oct 2021
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Glial ER and GAP junction mediated Ca2+ waves are crucial to maintain normal brain excitability

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Sep 2021
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Characterization of macrophage infiltration and polarization by double fluorescence immunostaining in mouse colonic mucosa

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An autoregulatory switch in sex-specific phf7 transcription causes loss of sexual identity and tumors in the Drosophila female germline

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  DOI: 10.1242/dev.192856
  
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The postnatal pancreatic microenvironment guides β cell maturation through BMP4 production

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BPS Publications

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The Hippo pathway uses different machinery to control cell fate and organ size

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Ablation of neuronal ADAM17 impairs oligodendrocyte differentiation and myelination

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Nutrient restriction causes reversible G2 arrest in Xenopus neural progenitors

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Semaphorin 2b Regulates Sleep-Circuit Formation in the Drosophila Central Brain

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Polarity Acquisition in Cortical Neurons Is Driven by Synergistic Action of Sox9-Regulated Wwp1 and Wwp2 E3 Ubiquitin Ligases and Intronic miR-140

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The Tricellular Junction Protein Sidekick Regulates Vertex Dynamics to Promote Bicellular Junction Extension

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Untitled document

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Untitled document

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Retinal ganglion cell survival and axon regeneration after optic nerve injury in naked mole‐rats

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Expansion microscopy-based imaging of nuclear structures in cultured cells

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TET1-mediated DNA hydroxymethylation regulates adult remyelination in mice

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Periphery signals generated by Piezo-mediated stomach stretch and Neuromedin-mediated glucose load regulate the Drosophila brain nutrient sensor

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Serotonin Receptor 2A Activation Promotes Evolutionarily Relevant Basal Progenitor Proliferation in the Developing Neocortex

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ATG4 family proteins drive phagophore growth independently of the LC3/GABARAP lipidation system

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  DOI: 10.1016/j.molcel.2021.03.001
  
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Platelets Facilitate the Wound-Healing Capability of Mesenchymal Stem Cells by Mitochondrial Transfer and Metabolic Reprogramming

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Complement C5a promotes antigen cross-presentation by Peyer’s patch monocyte-derived dendritic cells and drives a protective CD8+ T cell response

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Oligophrenin-1 moderates behavioral responses to stress by regulating parvalbumin interneuron activity in the medial prefrontal cortex

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Exploring the human lacrimal gland using organoids and single-cell sequencing

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Pexidartinib treatment in Alexander disease model mice reduces macrophage numbers and increases glial fibrillary acidic protein levels, yet has minimal impact on other disease phenotypes

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Identification of FoxP circuits involved in locomotion and object fixation in Drosophila

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Andrographolide suppresses NLRP3 inflammasome activation in microglia through induction of Parkin-mediated Mitophagy in in-vitro and in-vivo models of Parkinson disease

1
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CHD7 and Runx1 interaction provides a braking mechanism for hematopoietic differentiation

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BPS Publications

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  DOI: 10.1111/bph.15044
  
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Deficiency of microglial autophagy increases the density of oligodendrocytes and susceptibility to severe forms of seizures

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Arp2/3-dependent mechanical control of morphogenetic robustness in an inherently challenging environment

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BPS Publications

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  DOI: 10.1002/prp2.706
  
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bpspubs.onlinelibrary.wiley.com/doi/full/10.1002/prp2.706
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Microglial mTOR is neuronal protective and anti-epileptogenic in the pilocarpine model of temporal lobe epilepsy

1
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  DOI: 10.1523/JNEUROSCI.2754-19.2020
  
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jneurosci.org/content/40/40/7593
Dec 2020
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Andrographolide suppresses NLRP3 inflammasome activation in microglia through induction of Parkin-mediated Mitophagy in in-vitro and in-vivo models of Parkinson disease

1
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  AB_2535855
  
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Nov 2020
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Corneal nonmyelinating Schwann cells illuminated by single‐cell transcriptomics and visualized by protein biomarkers

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  DOI: 10.1002/jnr.24757
  
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onlinelibrary.wiley.com/doi/10.1002/jnr.24757
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Complement Signals Determine Opposite Effects of B Cells in Chemotherapy-Induced Immunity

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  DOI: 10.1016/j.cell.2020.02.015
  
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Homeostatic and tumourigenic activity of SOX2+ pituitary stem cells is controlled by the LATS/YAP/TAZ cascade

1
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  DOI: 10.7554/eLife.43996
  
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Pathogenic Potential of Hic1-Expressing Cardiac Stromal Progenitors

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Comprehensive Molecular Characterization Identifies Distinct Genomic and Immune Hallmarks of Renal Medullary Carcinoma

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A stochastic framework of neurogenesis underlies the assembly of neocortical cytoarchitecture

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Doublecortin like kinase 1 regulates α-Synuclein levels and toxicity

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The follicle epithelium in the Drosophila ovary is maintained by a small number of stem cells

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EGFR-Pak Signaling Selectively Regulates Glutamine Deprivation-Induced Macropinocytosis

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Hic1 Defines Quiescent Mesenchymal Progenitor Subpopulations with Distinct Functions and Fates in Skeletal Muscle Regeneration

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Remodeling of Bone Marrow Hematopoietic Stem Cell Niches Promotes Myeloid Cell Expansion during Premature or Physiological Aging

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Altering the Temporal Regulation of One Transcription Factor Drives Evolutionary Trade-Offs between Head Sensory Organs

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Donepezil‐induced oligodendrocyte differentiation is mediated through estrogen receptors

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  DOI: 10.1111/jnc.14927
  
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Non-canonical Wnt signaling regulates junctional mechanocoupling during angiogenic collective cell migration

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The Chemoattractant Receptor Ebi2 Drives Intranodal Naive CD4+ T Cell Peripheralization to Promote Effective Adaptive Immunity

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RSK-MASTL Pathway Delays Meiotic Exit in Mouse Zygotes to Ensure Paternal Chromosome Stability

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Type I Interferon Receptor Signaling of Neurons and Astrocytes Regulates Microglia Activation during Viral Encephalitis

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The LKB1-SIK Pathway Controls Dendrite Self-Avoidance in Purkinje Cells

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The Microglial Innate Immune Receptor TREM2 Is Required for Synapse Elimination and Normal Brain Connectivity

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Cell-Specific Imd-NF-κB Responses Enable Simultaneous Antibacterial Immunity and Intestinal Epithelial Cell Shedding upon Bacterial Infection

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Cellular Differentiation of Human Monocytes Is Regulated by Time-Dependent Interleukin-4 Signaling and the Transcriptional Regulator NCOR2

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Insm1 Induces Neural Progenitor Delamination in Developing Neocortex via Downregulation of the Adherens Junction Belt-Specific Protein Plekha7

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Transsynaptic Mapping of Second-Order Taste Neurons in Flies by trans-Tango

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Ribonucleotide Reductase Requires Subunit Switching in Hypoxia to Maintain DNA Replication

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  Alexa Fluor 555-conjugated goat anti-rat IgGInvitrogenCat# A21434
  
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An FAK-YAP-mTOR Signaling Axis Regulates Stem Cell-Based Tissue Renewal in Mice

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In Utero Exposure to Valproic Acid Induces Neocortical Dysgenesis via Dysregulation of Neural Progenitor Cell Proliferation/Differentiation

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