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    Primary ciliary protein kinase A activity in the prefrontal cortex modulates stress in mice
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    Development of apical out trophoblast stem cell derived organoids to model early human pregnancy
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    Novel CRISPR-Cas9 iPSC knockouts for PCCA and PCCB genes: advancing propionic acidemia research
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  5. Mar 2025
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    KCTD20 suppression mitigates excitotoxicity in tauopathy patient organoids
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    NEIL3 influences adult neurogenesis and behavioral pattern separation via WNT signaling
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    Outer radial glia promotes white matter regeneration after neonatal brain injury
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  9. Feb 2025
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    EHBP1 suppresses liver fibrosis in metabolic dysfunction-associated steatohepatitis
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    Inhibition of SUMOylation exacerbates neurological dysfunction and delays hematoma clearance after intracerebral hemorrhage in mice
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    Compositionally unique mitochondria in filopodia support cellular migration
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    Dendritic cell phagosomes recruit GRASP55 for export of antigen-loaded MHC molecules
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    HypoxyStat, a small-molecule form of hypoxia therapy that increases oxygen-hemoglobin affinity
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    Scaling iPSC production in different 3D platforms in suspension culture for their use in allogeneic regenerative therapies.
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    Canonical and non-canonical PRC1 differentially contribute to regulation of neural stem cell fate
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    Individualized patient tumor organoids faithfully preserve human brain tumor ecosystems and predict patient response to therapy
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    Acetyl-CoA synthesis in the skin is a key determinant of systemic lipid homeostasis
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    PI3K/AKT Signaling Mediates Stress-Inducible Amyloid Aggregation Through c-myc
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  21. Jan 2025
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    The expression of transcription factors in the human fetal subthalamic nucleus suggests its origin from the first hypothalamic prosomere
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    Neuroanatomical distribution of endogenous huntingtin and its immunohistochemical relationships with STB/HAP1 in the adult mouse brain and spinal cord
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    Cyclin-dependent kinase inhibitor p18 regulates lineage transitions of excitatory neurons, astrocytes, and interneurons in the mouse cortex
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    A spatiotemporal and machine-learning platform facilitates the manufacturing of hPSC-derived esophageal mucosa
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  27. Dec 2024
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    Expanding GABAergic Neuronal Diversity in iPSC-Derived Disease Models
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    DUX4-induced HSATII RNA accumulation drives protein aggregation impacting RNA processing pathways
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    Generation and characterization of novel induced pluripotent stem cell (iPSC) lines derived from three symptomatic carriers of a pathogenic MYH11 variant and two non-carrier relatives
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    Kir4.1-Dependent Astrocyte-Fast Motor Neuron Interactions Are Required for Peak Strength
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    Protocol for handling and using SOD1 mice for amyotrophic lateral sclerosis pre-clinical studies
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  33. Nov 2024
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    CEP192 localises mitotic Aurora-A activity by priming its interaction with TPX2
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    Biased cell adhesion organizes the Drosophila visual motion integration circuit
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    Generation of self-renewing neuromesodermal progenitors with neuronal and skeletal muscle bipotential from human embryonic stem cells
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    Time-resolved proximity proteomics uncovers a membrane tension-sensitive caveolin-1 interactome at the rear of migrating cells
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  38. Oct 2024
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    Protocol for generating a 3D culture of epiblast stem cells
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  40. Sep 2024
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    Large-scale map of RNA-binding protein interactomes across the mRNA life cycle
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    Molecular and spatial signatures of human and rat corpus cavernosum physiopathological processes at single-cell resolution
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    Targeting EGLN2/PHD1 protects motor neurons and normalizes the astrocytic interferon response
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  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ATAXIN-2 intermediate-length polyglutamine expansions elicit ALS-associated metabolic and immune phenotypes
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    Sex and disease regulate major histocompatibility complex class I expression in human lung epithelial cells
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    A bispecific antibody targeting EGFR and AXL delays resistance to osimertinib
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  47. Aug 2024
  48. www.nature.com www.nature.com
    LIFR regulates cholesterol-driven bidirectional hepatocyte–neutrophil cross-talk to promote liver regeneration
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    The tyrosine phosphatases LAR and PTPRδ act as receptors of the nidogen-tetanus toxin complex
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    Human liver sinusoidal endothelial cells support the development of functional human pluripotent stem cell-derived Kupffer cells
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    Generation of two hiPSC lines carrying compound heterozygous RDH12 mutations in a LCA patient
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    TNF-α and α-synuclein fibrils differently regulate human astrocyte immune reactivity and impair mitochondrial respiration
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  53. www.nature.com www.nature.com
    Table 1 Detailed information for key resources and fly stocks.
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  54. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Melanin‐concentrating hormone axons, but not orexin or tyrosine hydroxylase axons, innervate the claustrum in the rat: An immunohistochemical study
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    An integration-free induced pluripotent stem cell line from a 42-year-old female donor with the APOE-ε2/ε2 allele
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  56. Jul 2024
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    CircARAP2 controls sMICA-induced NK cell desensitization by erasing CTCF/PRC2-induced suppression in early endosome marker RAB5A
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    G2 arrest primes hematopoietic stem cells for megakaryopoiesis
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    Therapeutic potential of human microglia transplantation in a chimeric model of CSF1R-related leukoencephalopathy
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    Waves of regulated protein expression and phosphorylation rewire the proteome to drive gametogenesis in budding yeast
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    RNA 5-methylcytosine marks mitochondrial double-stranded RNAs for degradation and cytosolic release
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    Mutation-induced LZTR1 polymerization provokes cardiac pathology in recessive Noonan syndrome
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  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Disruption of EGF Feedback by Intestinal Tumors and Neighboring Cells in Drosophila
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  65. www.embopress.org www.embopress.org
    The tyrosine phosphatases LAR and PTPRδ act as receptors of the nidogen-tetanus toxin complex
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    Dystrophin 71 deficiency causes impaired aquaporin-4 polarization contributing to glymphatic dysfunction and brain edema in cerebral ischemia
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    Bidirectional activation of stem-like programs between metastatic cancer and alveolar type 2 cells within the niche
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  70. bsd.biomedcentral.com bsd.biomedcentral.com
    Testosterone deficiency promotes arterial stiffening independent of sex chromosome complement
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    Imaging brain glucose metabolism in vivo reveals propionate as a major anaplerotic substrate in pyruvate dehydrogenase deficiency
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  72. May 2024
  73. www.sciencedirect.com www.sciencedirect.com
    Tumor cells impair immunological synapse formation via central nervous system-enriched metabolite
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    FGD5 in basal cells induces CXCL14 secretion that initiates a feedback loop to promote murine mammary epithelial growth and differentiation
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  75. journals.biologists.com journals.biologists.com
    Myc promotes polyploidy in murine trophoblast cells and suppresses senescence
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    Transient caspase-mediated activation of caspase-activated DNase causes DNA damage required for phagocytic macrophage differentiation
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    Osr2 functions as a biomechanical checkpoint to aggravate CD8+ T cell exhaustion in tumor
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    Generation of a healthy heavy smoker patient-derived induced pluripotent stem cell line UHOMi007-A from peripheral blood mononuclear cells
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    Cell competition promotes metastatic intestinal cancer through a multistage process
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    Targeting low levels of MIF expression as a potential therapeutic strategy for ALS
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    Nurr1 overexpression in the primary motor cortex alleviates motor dysfunction induced by intracerebral hemorrhage in the striatum in mice
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    Combinatorial interpretation of BMP and WNT controls the decision between primitive streak and extraembryonic fates
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    A dynamin superfamily-like pseudoenzyme coordinates with MICOS to promote cristae architecture
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    The Drosophila Hippo pathway transcription factor Scalloped and its co-factors alter each other’s chromatin binding dynamics and transcription in vivo
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    The growth factor EPIREGULIN promotes basal progenitor cell proliferation in the developing neocortex
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    The growth factor EPIREGULIN promotes basal progenitor cell proliferation in the developing neocortex
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    Prophylactic treatment with the c-Abl inhibitor, neurotinib, diminishes neuronal damage and the convulsive state in pilocarpine-induced mice
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    Detection of newly synthesized RNA reveals transcriptional reprogramming during ZGA and a role of Obox3 in totipotency acquisition
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    ICAM-1 nanoclusters regulate hepatic epithelial cell polarity by leukocyte adhesion-independent control of apical actomyosin
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    Human motor units in microfluidic devices are impaired by FUS mutations and improved by HDAC6 inhibition
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    Neuronal activity rapidly reprograms dendritic translation via eIF4G2:uORF binding
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    KCNJ2 inhibition mitigates mechanical injury in a human brain organoid model of traumatic brain injury
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    Basal delamination during mouse gastrulation primes pluripotent cells for differentiation
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    Vangl-dependent mesenchymal thinning shapes the distal lung during murine sacculation
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    Dissecting Gene Expression Networks in the Developing Hippocampus through the Lens of NEIL3 Depletion
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    Spatial patterning controls neuron numbers in the Drosophila visual system
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    Two-photon live imaging of direct glia-to-neuron conversion in the mouse cortex
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    Engineered FSHD mutations results in D4Z4 heterochromatin disruption and feedforward DUX4 network activation
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    Characterizing enteric neurons in dopamine transporter (DAT)-Cre reporter mice reveals dopaminergic subtypes with dual-transmitter content
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    Characteristics of A-type voltage-gated K+ currents expressed on sour-sensing type III taste receptor cells in mice
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  105. Feb 2024
  106. www.sciencedirect.com www.sciencedirect.com
    Sustained antidepressant effects of ketamine metabolite involve GABAergic inhibition-mediated molecular dynamics in aPVT glutamatergic neurons
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    Ependymocytes control cerebrospinal fluid flow to the peripheral organs through periaxonal pathway
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    A retroviral link to vertebrate myelination through retrotransposon-RNA-mediated control of myelin gene expression
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    Measurement of adhesion and traction of cells at high yield (MATCHY) reveals an energetic ratchet driving nephron condensation
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    Patronin Regulates Presynaptic Microtubule Organization and Neuromuscular Junction Development in Drosophila
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    Pathway-specific inputs to the superior colliculus support flexible responses to visual threat
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    Discrete prefrontal neuronal circuits determine repeated stress-induced behavioral phenotypes in male mice
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    Ventral pallidum neurons projecting to the ventral tegmental area reinforce but do not invigorate reward-seeking behavior
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    Two parabrachial Cck neurons involved in the feedback control of thirst or salt appetite
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    Fibroblast subpopulations in Systemic Sclerosis – Functional implications of individual subpopulations and correlations with clinical features
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    Tumor necrosis factor-stimulated gene-6 ameliorates early brain injury after subarachnoid hemorrhage by suppressing NLRC4 inflammasome-mediated astrocyte pyroptosis
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    Choroid plexus mast cells drive tumor-associated hydrocephalus
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    Efficient selection of knocked-in pluripotent stem cells using a dual cassette cellular elimination system
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  125. www.mdpi.com www.mdpi.com
    Olanzapine Effects on Parvalbumin/GAD67 Cell Numbers in Layers/Subregions of Dorsal Hippocampus of Chronically Socially Isolated Rats
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  126. link.springer.com link.springer.com
    In Situ Decellularization of Tissues Applied to the Topographical Analysis of Tumor-Associated Extracellular Matrix
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  127. Nov 2023
  128. www.sciencedirect.com www.sciencedirect.com
    Nanoscale organization of the endogenous ASC speck
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    Robust small molecule-aided cardiac reprogramming systems selective to cardiac fibroblasts
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    Structured wound angiogenesis instructs mesenchymal barrier compartments in the regenerating nerve
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    CLIP-Seq analysis enables the design of protective ribosomal RNA bait oligonucleotides against C9ORF72 ALS/FTD poly-GR pathophysiology
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  132. www.biorxiv.org www.biorxiv.org
    Rho/ROCK activity tunes cell compartment segregation and differentiation in nephron-forming niches
    1
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  133. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CLIP-Seq analysis enables the design of protective ribosomal RNA bait oligonucleotides against C9ORF72 ALS/FTD poly-GR pathophysiology
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  134. www.sciencedirect.com www.sciencedirect.com
    Neuronal activation of Gαq EGL-30/GNAQ late in life rejuvenates cognition across species
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  135. www.sciencedirect.com www.sciencedirect.com
    Neuroepithelial organoid patterning is mediated by a neighborhood watch mechanism
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    Mitf is a Schwann cell sensor of axonal integrity that drives nerve repair
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  137. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Social withdrawal and anxiety-like behavior have an impact on zebrafish adult neurogenesis
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  138. Oct 2023
  139. www.sciencedirect.com www.sciencedirect.com
    Choroid plexuses carry nodal-like cilia that undergo axoneme regression from early adult stage
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    A neural pathway underlying hunger modulation of sexual receptivity in Drosophila females
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    Tubule jamming in the developing mouse kidney creates cyclical mechanical stresses in nephron-forming niches
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  142. www.nature.com www.nature.com
    Chromatin-modifying enzymes as modulators of nuclear size during lineage differentiation
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  143. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Treadmill exercise improves hippocampal neural plasticity and relieves cognitive deficits in a mouse model of epilepsy
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  144. www.science.org www.science.org
    Loss of function of the ALS-associated NEK1 kinase disrupts microtubule homeostasis and nuclear import
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    The RBPMSCreERT2-tdTomato mouse line for study retinal and vascular relevant diseases
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    Metformin inhibits inflammatory response and endoplasmic reticulum stress to improve hypothalamic aging in obese mice
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    Complement factor D targeting protects endotheliopathy in organoid and monkey models of COVID-19
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  148. Sep 2023
  149. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pathway-specific inputs to the superior colliculus support flexible responses to visual threat
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    A cell therapy approach to restore microglial Trem2 function in a mouse model of Alzheimer’s disease
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  151. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Histone bivalency regulates the timing of cerebellar granule cell development
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  152. www.sciencedirect.com www.sciencedirect.com
    Centrins control chicken cone cell lipid droplet dynamics through lipid-droplet-localized SPDL1
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    3D-cultured blastoids model human embryogenesis from pre-implantation to early gastrulation stages
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  154. Aug 2023
  155. www.science.org www.science.org
    Loss of function of the ALS-associated NEK1 kinase disrupts microtubule homeostasis and nuclear import
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  156. 52.53.155.43 52.53.155.43
    L858R emerges as a potential biomarker predicting response of lung cancer models to anti-EGFR antibodies: Comparison of osimertinib vs. cetuximab
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  157. www.sciencedirect.com www.sciencedirect.com
    The C9ORF72 repeat expansion alters neurodevelopment
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  158. Jul 2023
  159. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Characterization of clock-related proteins and neuropeptides in Drosophila littoralis and their putative role in diapause
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      DOI: 10.1002/cne.25522

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    Genome-scale mapping of DNA damage suppressors through phenotypic CRISPR-Cas9 screens
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  161. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Defective neurite elongation and branching in Nibp/Trappc9 deficient zebrafish and mice
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      DOI: 10.7150/ijbs.78489

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  162. www.sciencedirect.com www.sciencedirect.com
    The kinesin Kif21b regulates radial migration of cortical projection neurons through a non-canonical function on actin cytoskeleton
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    Blocking an epitope of misfolded SOD1 ameliorates disease phenotype in a model of amyotrophic lateral sclerosis
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  164. Jun 2023
  165. www.sciencedirect.com www.sciencedirect.com
    Chemogenetic and optogenetic stimulation of zona incerta GABAergic neurons ameliorates motor impairment in Parkinson's disease
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    Excitatory amino acid transporter 1 supports adult hippocampal neural stem cell self-renewal
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  167. www.nature.com www.nature.com
    Targeting neuronal and glial cell types with synthetic promoter AAVs in mice, non-human primates and humans
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    A protocol for the differentiation of human embryonic stem cells into midbrain dopaminergic neurons
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    Structures of sperm flagellar doublet microtubules expand the genetic spectrum of male infertility
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    Activity-dependent local protection and lateral inhibition control synaptic competition in developing mitral cells in mice
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  171. www.nature.com www.nature.com
    Genetic recording of in vivo cell proliferation by ProTracer
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  172. www.jneurosci.org www.jneurosci.org
    The SphK1/S1P axis regulates synaptic vesicle endocytosis via TRPC5 channels
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  173. May 2023
  174. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Phosphorylation of PSD-95 at serine 73 in dCA1 is required for extinction of contextual fear
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      DOI: 10.1371/journal.pbio.3002106

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  175. www.sciencedirect.com www.sciencedirect.com
    Human Induced pluripotent stem cell (iPSC) line (HEBHMUi014-A) derived from a patient with Alzheimer's disease
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    Differentiation of stem cell-derived pancreatic progenitors into insulin-secreting islet clusters in a multiwell-based static 3D culture system
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    Establishment of bovine trophoblast stem cells
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    Replication stress impairs chromosome segregation and preimplantation development in human embryos
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    The ubiquitin-ligase TRAF6 and TGFβ type I receptor form a complex with Aurora kinase B contributing to mitotic progression and cytokinesis in cancer cells
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  180. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An atlas of endogenous DNA double-strand breaks arising during human neural cell fate determination
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  181. www.sciencedirect.com www.sciencedirect.com
    Generation of a genetically-modified induced pluripotent stem cell line harboring a Noonan syndrome-associated gene variant MRAS p.G23V
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  182. Apr 2023
  183. www.sciencedirect.com www.sciencedirect.com
    Generation of a genetically-modified induced pluripotent stem cell line harboring an oncogenic gene variant KRAS p.G12V
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    Mitochondrial cannabinoid receptors gate corticosterone impact on novel object recognition
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    A Prime Editor efficiently repaired human induced pluripotent stem cells with AR gene mutation (c.2710G > A; p. V904M)
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  186. 52.53.155.43 52.53.155.43
    Boosting BDNF in muscle rescues impaired in vivo axonal transport in a mouse model of DI-CMTC peripheral neuropathy
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  187. www.sciencedirect.com www.sciencedirect.com
    Macrophage CD5L is a target for cancer immunotherapy
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  188. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Three-plane description of astroglial architecture and gliovascular connections of area postrema in rat: Long tanycyte connections to other parts of brainstem
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  189. Mar 2023
  190. 52.53.155.43 52.53.155.43
    Remodeling of the Ribosomal Quality Control and Protein Translation by a Viral Ubiquitin Deconjugase
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  191. europepmc.org europepmc.org
    Jarid2 promotes temporal progression of retinal progenitors via repression of Foxp1
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    Synaptotagmin-3 interactions with GluA2 mediate brain damage and impair functional recovery in stroke
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  193. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MeCP2 regulates Gdf11, a dosage-sensitive gene critical for neurological function
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    Post-translational proteomics platform identifies neurite outgrowth impairments in Parkinson’s disease GBA-N370S dopamine neurons
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    hPSC-derived sacral neural crest enables rescue in a severe model of Hirschsprung’s disease
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    Induced human pluripotent stem cells (HEBHMUi013-A) derived from a patient of sporadic Alzheimer's disease
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    Single-cell transcriptomic profiling redefines the origin and specification of early adrenogonadal progenitors
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  198. Feb 2023
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    Evolutionary origins and interactomes of human, young microproteins and small peptides translated from short open reading frames
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  200. www.embopress.org www.embopress.org
    Pericyte stem cells induce Ly6G+ cell accumulation and immunotherapy resistance in pancreatic cancer
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    Quantitative trait loci on chromosomes 9 and 19 modulate AII amacrine cell number in the mouse retina
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    Natural variation in gene expression and viral susceptibility revealed by neural progenitor cell villages
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    SYF2 suppression mitigates neurodegeneration in models of diverse forms of ALS
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    Generation of a ST3GAL3 null mutant induced pluripotent stem cell (iPSC) line (UKWMPi002-A-3) by CRISPR/Cas9 genome editing
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  205. Jan 2023
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    An in vivo avian model of human melanoma to perform rapid and robust preclinical studies
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    FUS ALS neurons activate major stress pathways and reduce translation as an early protective mechanism against neurodegeneration
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    The developing murine kidney actively negotiates geometric packing conflicts to avoid defects
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    Analysis of mitochondrial double-stranded RNAs in human cells
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    Phosphorylation of PSD-95 at Serine 73 in dCA1 is required for extinction of contextual fear
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    Artificial extracellular matrix scaffolds of mobile molecules enhance maturation of human stem cell-derived neurons
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  213. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Enhancer architecture and chromatin accessibility constrain phenotypic space during Drosophila development
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    Structural and functional map for forelimb movement phases between cortex and medulla
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    Expansion microscopy of the chick embryo neural tube to overcome molecular crowding at the centrosomes-cilia
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    Generation of a human embryonic stem cell line (SKLRMe004-A) carrying NKX2.5-EGFP and TBX5-Tdtomato dual fluorescent reporters
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