Hypothesis

31 Matching Annotations

Oct 2026
pubs.acs.org pubs.acs.org

Conditional Mutant MAPT Overexpression in Neural Organoids Elicits Robust Tau Accumulation and Pathological Transcriptomic Responses

1
1. scibot 08 Oct 2026
  
  in Public
  
  RRID:AB_2536235
  
  DOI: 10.1021/acschemneuro.6c00376
  
  Resource: (Thermo Fisher Scientific Cat# AHB0042, RRID:AB_2536235)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2536235
  
  What is this?
  
  RRID:AB_2536235
Visit annotations in context

Tags

RRID:AB_2536235

Annotators

scibot

URL

pubs.acs.org/acncdm/article/doi/10.1021/acschemneuro.6c00376/5440359/Conditional-Mutant-MAPT-Overexpression-in-Neural
May 2026
www.biorxiv.org www.biorxiv.org

tRNA-derived fragments elevated in Alzheimer’s disease facilitate Tau aggregation

1
1. scibot 29 May 2026
  
  in Public
  
  RRID:AB_2536235
  
  DOI: 10.64898/2026.05.17.725757
  
  Resource: (Thermo Fisher Scientific Cat# AHB0042, RRID:AB_2536235)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2536235
  
  What is this?
  
  RRID:AB_2536235
Visit annotations in context

Tags

RRID:AB_2536235

Annotators

scibot

URL

biorxiv.org/content/10.64898/2026.05.17.725757v1
Apr 2026
54.241.53.176 54.241.53.176

2026.04.20.719548.full-html.html

1
1. scibot 30 Apr 2026
  
  in Public
  
  AB_2536235
  
  DOI: 10.64898/2026.04.20.719548
  
  Resource: (Thermo Fisher Scientific Cat# AHB0042, RRID:AB_2536235)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2536235
  
  What is this?
  
  RRID:AB_2536235
Visit annotations in context

Tags

RRID:AB_2536235

Annotators

scibot

URL

54.241.53.176/c1c00486dbe489784861e140175fcdc5fdf9d6eb/2026.04.20.719548.full-html.html
www.sciencedirect.com www.sciencedirect.com

Phosphoproteomics identifies Rho-Kinase-associated phospho-signaling and autophagy-associated alterations in the medial prefrontal cortex of a schizophrenia-related mouse model

1
1. scibot 29 Apr 2026
  
  in Public
  
  RRID:AB_2536235
  
  DOI: 10.1016/j.phrs.2026.108201
  
  Resource: (Thermo Fisher Scientific Cat# AHB0042, RRID:AB_2536235)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2536235
  
  What is this?
  
  RRID:AB_2536235
Visit annotations in context

Tags

RRID:AB_2536235

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1043661826001167
Mar 2026
www.sciencedirect.com www.sciencedirect.com

Tanycytic degeneration impairs tau clearance and contributes to Alzheimer’s disease pathology

1
1. scibot 06 Mar 2026
  
  in Public
  
  RRID:AB_2536235
  
  DOI: 10.1016/j.cpblue.2026.100003
  
  Resource: (Thermo Fisher Scientific Cat# AHB0042, RRID:AB_2536235)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2536235
  
  What is this?
  
  RRID:AB_2536235
Visit annotations in context

Tags

RRID:AB_2536235

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S3051383926000010
Nov 2025
www.sciencedirect.com:5037 www.sciencedirect.com:5037

A 16-amino acid peptide delays the progression of motor neuron degeneration and pathogenic symptoms in ALS models

1
1. scibot 29 Nov 2025
  
  in Public
  
  RRID:AB_2536235
  
  DOI: 10.1016/j.neurot.2025.e00806
  
  Resource: (Thermo Fisher Scientific Cat# AHB0042, RRID:AB_2536235)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2536235
  
  What is this?
  
  RRID:AB_2536235
Visit annotations in context

Tags

RRID:AB_2536235

Annotators

scibot

URL

sciencedirect.com:5037/science/article/pii/S1878747925002843
Sep 2025
www.tandfonline.com www.tandfonline.com

Impaired MAPT/tau-secretory lysosomes are linked to cognitive vulnerability in Alzheimer patients

1
1. scibot 03 Sep 2025
  
  in Public
  
  AB_2536235
  
  DOI: 10.1080/15548627.2025.2552905
  
  Resource: (Thermo Fisher Scientific Cat# AHB0042, RRID:AB_2536235)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2536235
  
  What is this?
  
  RRID:AB_2536235
Visit annotations in context

Tags

RRID:AB_2536235

Annotators

scibot

URL

tandfonline.com/doi/full/10.1080/15548627.2025.2552905
Apr 2025
www.sciencedirect.com www.sciencedirect.com

Human MAPT knockin mouse models of frontotemporal dementia for the neurodegenerative research community

1
1. scibot 15 Apr 2025
  
  in Public
  
  RRID:AB_2536235
  
  DOI: 10.1016/j.crmeth.2025.101024
  
  Resource: (Thermo Fisher Scientific Cat# AHB0042, RRID:AB_2536235)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2536235
  
  What is this?
  
  RRID:AB_2536235
Visit annotations in context

Tags

RRID:AB_2536235

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2667237525000608
Mar 2025
link.springer.com link.springer.com

Biochemical characterization of Tau protein changes and amyloid dynamics in a novel non-transgenic rat model of tauopathy

1
1. scibot 25 Mar 2025
  
  in Public
  
  RRID:AB_2536235
  
  DOI: 10.1007/s00702-025-02909-z
  
  Resource: (Thermo Fisher Scientific Cat# AHB0042, RRID:AB_2536235)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2536235
  
  What is this?
  
  RRID:AB_2536235
Visit annotations in context

Tags

RRID:AB_2536235

Annotators

scibot

URL

link.springer.com/article/10.1007/s00702-025-02909-z
Feb 2025
link.springer.com link.springer.com

Involvement of CRMP2 Phosphorylation in Amyloid Beta-induced Tau Phosphorylation of Hippocampal Neurons in Alzheimer’s Disease Mouse Model

1
1. scibot 04 Feb 2025
  
  in Public
  
  AB_2536235
  
  DOI: 10.1007/s12035-025-04721-y
  
  Resource: (Thermo Fisher Scientific Cat# AHB0042, RRID:AB_2536235)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2536235
  
  What is this?
  
  RRID:AB_2536235
Visit annotations in context

Tags

RRID:AB_2536235

Annotators

scibot

URL

link.springer.com/article/10.1007/s12035-025-04721-y
Jul 2024
www.sciencedirect.com www.sciencedirect.com

Intracellular tau fragment droplets serve as seeds for tau fibrils

1
1. scibot 25 Jul 2024
  
  in Public
  
  AB_2536235
  
  DOI: 10.1016/j.str.2024.06.018
  
  Resource: (Thermo Fisher Scientific Cat# AHB0042, RRID:AB_2536235)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2536235
  
  What is this?
  
  RRID:AB_2536235
Visit annotations in context

Tags

RRID:AB_2536235

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0969212624002363
Mar 2024
www.sciencedirect.com www.sciencedirect.com

P-tau217 correlates with neurodegeneration in Alzheimer’s disease, and targeting p-tau217 with immunotherapy ameliorates murine tauopathy

2
1. scibot 21 Mar 2024
  
  in Public
  
  RRID:AB_2536235
  
  DOI: 10.1016/j.neuron.2024.02.017
  
  Resource: (Thermo Fisher Scientific Cat# AHB0042, RRID:AB_2536235)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2536235
  
  What is this?
  
  RRID:AB_2536235
2. scibot 21 Mar 2024
  
  in Public
  
  RRID:AB_2536235
  
  DOI: 10.1016/j.neuron.2024.02.017
  
  Resource: (Thermo Fisher Scientific Cat# AHB0042, RRID:AB_2536235)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2536235
  
  What is this?
  
  RRID:AB_2536235
Visit annotations in context

Tags

RRID:AB_2536235

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0896627324001272
Feb 2024
www.sciencedirect.com www.sciencedirect.com

Single-nucleus RNA sequencing demonstrates an autosomal dominant Alzheimer’s disease profile and possible mechanisms of disease protection

1
1. scibot 29 Feb 2024
  
  in Public
  
  RRID:AB_2536235
  
  DOI: 10.1016/j.neuron.2024.02.009
  
  Resource: (Thermo Fisher Scientific Cat# AHB0042, RRID:AB_2536235)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2536235
  
  What is this?
  
  RRID:AB_2536235
Visit annotations in context

Tags

RRID:AB_2536235

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S089662732400093X
Jul 2023
www.sciencedirect.com www.sciencedirect.com

Hepatic soluble epoxide hydrolase activity regulates cerebral Aβ metabolism and the pathogenesis of Alzheimer’s disease in mice

1
1. scibot 06 Jul 2023
  
  in Public
  
  RRID:AB_2536235
  
  DOI: 10.1016/j.neuron.2023.06.002
  
  Resource: (Thermo Fisher Scientific Cat# AHB0042, RRID:AB_2536235)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2536235
  
  What is this?
  
  RRID:AB_2536235
Visit annotations in context

Tags

RRID:AB_2536235

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0896627323004373
Jun 2023
www.biorxiv.org www.biorxiv.org

KIBRA repairs synaptic plasticity and promotes resilience to tauopathy-related memory loss

1
1. scibot 23 Jun 2023
  
  in Public
  
  RRID:AB_2536235
  
  DOI: 10.1101/2023.06.12.543777
  
  Resource: (Thermo Fisher Scientific Cat# AHB0042, RRID:AB_2536235)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2536235
  
  What is this?
  
  RRID:AB_2536235
Visit annotations in context

Tags

RRID:AB_2536235

Annotators

scibot

URL

biorxiv.org/content/10.1101/2023.06.12.543777v1
www.sciencedirect.com www.sciencedirect.com

Activity-dependent tau cleavage by caspase-3 promotes neuronal dysfunction and synaptotoxicity

1
1. scibot 07 Jun 2023
  
  in Public
  
  RRID:AB_2536235
  
  DOI: 10.1016/j.isci.2023.106905
  
  Resource: (Thermo Fisher Scientific Cat# AHB0042, RRID:AB_2536235)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2536235
  
  What is this?
  
  RRID:AB_2536235
Visit annotations in context

Tags

RRID:AB_2536235

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2589004223009823
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

BPS Publications

1
1. scibot 01 Jun 2023
  
  in Public
  
  RRID:AB_2536235
  
  DOI: 10.1111/bph.16093
  
  Resource: (Thermo Fisher Scientific Cat# AHB0042, RRID:AB_2536235)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2536235
  
  What is this?
  
  RRID:AB_2536235
Visit annotations in context

Tags

RRID:AB_2536235

Annotators

scibot

URL

bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16093
Feb 2023
www.sciencedirect.com www.sciencedirect.com

Cofilin promotes tau pathology in Alzheimer’s disease

1
1. scibot 23 Feb 2023
  
  in Public
  
  RRID:AB_2536235
  
  DOI: 10.1016/j.celrep.2023.112138
  
  Resource: (Thermo Fisher Scientific Cat# AHB0042, RRID:AB_2536235)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2536235
  
  What is this?
  
  RRID:AB_2536235
Visit annotations in context

Tags

RRID:AB_2536235

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124723001493
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Neuroprotective Effects of a Multi-Herbal Extract on Axonal and Synaptic Disruption in Vitro and Cognitive Impairment in Vivo

1
1. scibot 15 Feb 2023
  
  in Public
  
  AB_2536235
  
  DOI: 10.3233/ADR-220056
  
  Resource: (Thermo Fisher Scientific Cat# AHB0042, RRID:AB_2536235)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2536235
  
  What is this?
  
  RRID:AB_2536235
Visit annotations in context

Tags

RRID:AB_2536235

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC9912829/
Aug 2022
www.sciencedirect.com www.sciencedirect.com

Ethanol sustains phosphorylated tau protein in the cultured neonatal rat hippocampus: Implications for fetal alcohol spectrum disorders

1
1. scibot 16 Aug 2022
  
  in Public
  
  RRID:AB_2536235
  
  DOI: 10.1016/j.alcohol.2022.07.007
  
  Resource: (Thermo Fisher Scientific Cat# AHB0042, RRID:AB_2536235)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2536235
  
  What is this?
  
  RRID:AB_2536235
Visit annotations in context

Tags

RRID:AB_2536235

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0741832922000696
Aug 2021
www.biorxiv.org www.biorxiv.org

Untitled document

1
1. scibot 13 Aug 2021
  
  in Public
  
  AB_2536235
  
  DOI: 10.1101/612911
  
  Resource: (Thermo Fisher Scientific Cat# AHB0042, RRID:AB_2536235)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2536235
  
  What is this?
  
  RRID:AB_2536235
Visit annotations in context

Tags

RRID:AB_2536235

Annotators

scibot

URL

biorxiv.org/content/10.1101/612911v1
Feb 2021
elifesciences.org elifesciences.org

Targeted degradation of aberrant tau in frontotemporal dementia patient-derived neuronal cell models

1
1. scibot 26 Feb 2021
  
  in Public
  
  RRID:AB_2536235
  
  DOI: 10.7554/eLife.45457
  
  Resource: (Thermo Fisher Scientific Cat# AHB0042, RRID:AB_2536235)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2536235
  
  What is this?
  
  RRID:AB_2536235
Visit annotations in context

Tags

RRID:AB_2536235

Annotators

scibot

URL

elifesciences.org/articles/45457
Sep 2020
www.sciencedirect.com www.sciencedirect.com

Tau Reduction Prevents Key Features of Autism in Mouse Models

1
1. scibot 23 Sep 2020
  
  in Public
  
  RRID:AB_2536235
  
  DOI: 10.1016/j.neuron.2020.01.038
  
  Resource: (Thermo Fisher Scientific Cat# AHB0042, RRID:AB_2536235)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2536235
  
  What is this?
  
  RRID:AB_2536235 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_2536235

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0896627320300659
onlinelibrary.wiley.com onlinelibrary.wiley.com

Correcting abnormalities in miR‐124/PTPN1 signaling rescues tau pathology in Alzheimer’s disease

1
1. scibot 23 Sep 2020
  
  in Public
  
  AB_2536235
  
  DOI: 10.1111/jnc.14961
  
  Resource: (Thermo Fisher Scientific Cat# AHB0042, RRID:AB_2536235)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2536235
  
  What is this?
  
  RRID:AB_2536235 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_2536235

Annotators

scibot

URL

onlinelibrary.wiley.com/doi/10.1111/jnc.14961
www.sciencedirect.com www.sciencedirect.com

Fyn Kinase Controls Tau Aggregation In Vivo

1
1. scibot 17 Sep 2020
  
  in Public
  
  RRID:AB_2536235
  
  DOI: 10.1016/j.celrep.2020.108045
  
  Resource: (Thermo Fisher Scientific Cat# AHB0042, RRID:AB_2536235)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2536235
  
  What is this?
  
  RRID:AB_2536235 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_2536235

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124720310305
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A soluble truncated tau species related to cognitive dysfunction is elevated in the brain of cognitively impaired human individuals

1
1. scibot 06 Sep 2020
  
  in Public
  
  RRID:AB_2536235
  
  DOI: 10.1038/s41598-020-60777-x
  
  Resource: (Thermo Fisher Scientific Cat# AHB0042, RRID:AB_2536235)
  
  Curator: @evieth
  
  SciCrunch record: RRID:AB_2536235
  
  What is this?
  
  RRID:AB_2536235 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_2536235

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC7052165/
Jan 2020
onlinelibrary.wiley.com onlinelibrary.wiley.com

High specificity of widely used phospho‐tau antibodies validated using a quantitative whole‐cell based assay

1
1. scibot 13 Jan 2020
  
  in Public
  
  AB_2536235
  
  DOI: 10.1111/jnc.14830
  
  Resource: (Thermo Fisher Scientific Cat# AHB0042, RRID:AB_2536235)
  
  Curator: @Naa003
  
  SciCrunch record: AB_2536235
  
  What is this?
  
  RRID:AB_2536235 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_2536235

Annotators

scibot

URL

onlinelibrary.wiley.com/doi/10.1111/jnc.14830
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_2536235
  
  DOI: 10.7554/eLife.45457
  
  Resource: (Thermo Fisher Scientific Cat# AHB0042, RRID:AB_2536235)
  
  Curator: @evieth
  
  SciCrunch record: RRID:AB_2536235
  
  What is this?
  
  RRID:AB_2536235 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_2536235

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC6450673/
www.sciencedirect.com www.sciencedirect.com

Secretion of Tau via an Unconventional Non-vesicular Mechanism

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_2536235
  
  DOI: 10.1016/j.celrep.2018.10.078
  
  Resource: (Thermo Fisher Scientific Cat# AHB0042, RRID:AB_2536235)
  
  Curator: @evieth
  
  SciCrunch record: RRID:AB_2536235
  
  What is this?
  
  RRID:AB_2536235 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_2536235

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124718316826
www.sciencedirect.com www.sciencedirect.com

Untitled document

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_2536235
  
  DOI: 10.1016/j.celrep.2019.01.023
  
  Resource: (Thermo Fisher Scientific Cat# AHB0042, RRID:AB_2536235)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2536235
  
  What is this?
  
  RRID:AB_2536235 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_2536235

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124719300324