120 Matching Annotations
  1. Last 7 days
  2. www.sciencedirect.com www.sciencedirect.com
    Tubulin sequence divergence is associated with the use of distinct microtubule regulators
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    1. scibot 18 Dec 2024
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      DOI: 10.1016/j.cub.2024.11.022

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    sciencedirect.com/science/article/pii/S096098222401563X
  3. Dec 2024
  4. www.sciencedirect.com www.sciencedirect.com
    tp53 R217H and R242H mutant zebrafish exhibit dysfunctional p53 hallmarks and recapitulate Li-Fraumeni syndrome phenotypes
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      DOI: 10.1016/j.bbadis.2024.167612

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    sciencedirect.com/science/article/pii/S0925443924006069
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    Mechanistic basis for the emergence of EPS1 as a catalyst in salicylic acid biosynthesis of Brassicaceae
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      DOI: 10.1038/s41467-024-54437-1

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    nature.com/articles/s41467-024-54437-1
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    Covalent targeting of splicing in T cells
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    1. scibot 02 Dec 2024
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      DOI: 10.1016/j.chembiol.2024.10.010

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    sciencedirect.com/science/article/pii/S2451945624004458
  7. Sep 2024
  8. onlinelibrary.wiley.com onlinelibrary.wiley.com
    A biallelic mutation in CACNA2D2 associated with developmental and epileptic encephalopathy affects calcium channel-dependent as well as synaptic functions of α2δ-2
    1
    1. scibot 27 Sep 2024
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      DOI: 10.1111/jnc.16197

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    onlinelibrary.wiley.com/doi/10.1111/jnc.16197
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Systems mapping of bidirectional endosomal transport through the crowded cell
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    1. scibot 17 Sep 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11466077/
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    Antiviral RNA interference inhibits virus vertical transmission in plants
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    1. scibot 10 Sep 2024
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    sciencedirect.com/science/article/pii/S1931312824003160
  11. Aug 2024
  12. www.biorxiv.org www.biorxiv.org
    tp53 R217H and R242H Mutant Zebrafish Exhibit Dysfunctional p53 Hallmarks and Recapitulate Li-Fraumeni Syndrome Phenotypes
    1
    1. scibot 20 Aug 2024
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      DOI: 10.1101/2024.07.31.605368

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    biorxiv.org/content/10.1101/2024.07.31.605368v1
  13. Jul 2024
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Toxicity of C9orf72-associated dipeptide repeat peptides is modified by commonly used protein tags
    1
    1. scibot 27 Jul 2024
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      DOI: 10.26508/lsa.202201739

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    ncbi.nlm.nih.gov/pmc/articles/PMC10262077/
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    Repeat length of C9orf72-associated glycine–alanine polypeptides affects their toxicity
    1
    1. scibot 24 Jul 2024
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      DOI: 10.1186/s40478-023-01634-6

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    ncbi.nlm.nih.gov/pmc/articles/PMC10463776/
  16. May 2024
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    Loss of POLE3-POLE4 unleashes replicative gap accumulation upon treatment with PARP inhibitors
    1
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      DOI: 10.1016/j.celrep.2024.114205

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    sciencedirect.com/science/article/pii/S2211124724005333
  18. Apr 2024
  19. www.nature.com www.nature.com
    CHD4 acts as a prognostic factor and drives radioresistance in HPV negative HNSCC
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      DOI: 10.1038/s41598-024-58958-z

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    nature.com/articles/s41598-024-58958-z
  20. Mar 2024
  21. www.sciencedirect.com www.sciencedirect.com
    BLMP-1 is a critical temporal regulator of dietary-restriction-induced response in Caenorhabditis elegans
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      DOI: 10.1016/j.celrep.2024.113959

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    sciencedirect.com/science/article/pii/S2211124724002870
  22. Feb 2024
  23. www.sciencedirect.com www.sciencedirect.com
    Heat stress promotes Arabidopsis AGO1 phase separation and association with stress granule components
    2
    1. scibot 29 Feb 2024
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      DOI: 10.1016/j.isci.2024.109151

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      DOI: 10.1016/j.isci.2024.109151

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    sciencedirect.com/science/article/pii/S2589004224003729
  24. 52.53.155.43 52.53.155.43
    A modified mouse model of Friedreich's ataxia with conditional Fxn allele homozygosity delays onset of cardiomyopathy
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      DOI: 10.1152/ajpheart.00496.2023

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      DOI: 10.1152/ajpheart.00496.2023

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    52.53.155.43/6e33d55472e195d6adca9c28447508adb76e083a/perfitt-et-al-2024-a-modified-mouse-model-of-friedreich-s-ataxia-with-conditional-fxn-allele-homozygosity-delays-onset-html.html
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A small-molecule degrader selectively inhibits the growth of ALK-rearranged lung cancer with ceritinib resistance
    1
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      DOI: 10.1016/j.isci.2024.109015

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    ncbi.nlm.nih.gov/pmc/articles/PMC10847737/
  26. Jan 2024
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    ABCG2 is an itaconate exporter that limits antibacterial innate immunity by alleviating TFEB-dependent lysosomal biogenesis
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      DOI: 10.1016/j.cmet.2023.12.015

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    sciencedirect.com/science/article/pii/S1550413123004655
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    Dynamic IL-6R/STAT3 signaling leads to heterogeneity of metabolic phenotype in pancreatic ductal adenocarcinoma cells
    1
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      DOI: 10.1016/j.celrep.2023.113612

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    sciencedirect.com/science/article/pii/S2211124723016248
  29. Dec 2023
  30. www.sciencedirect.com www.sciencedirect.com
    Phosphoprotein dynamics of interacting T cells and tumor cells by HySic
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      DOI: 10.1016/j.celrep.2023.113598

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    sciencedirect.com/science/article/pii/S2211124723016108
  31. Nov 2023
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Taste receptor type 1 member 3 enables western diet-induced anxiety in mice
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      DOI: 10.1186/s12915-023-01723-x

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    ncbi.nlm.nih.gov/pmc/articles/PMC10626698/
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    Pigmented skin exhibits accelerated wound healing compared to the nonpigmented skin in Guinea pig model
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      DOI: 10.1016/j.isci.2023.108159

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    sciencedirect.com/science/article/pii/S2589004223022368
  34. Oct 2023
  35. www.sciencedirect.com www.sciencedirect.com
    Development of novel cytoprotective small compounds inhibiting mitochondria-dependent cell death
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      DOI: 10.1016/j.isci.2023.107916

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    sciencedirect.com/science/article/pii/S2589004223019934
  36. Sep 2023
  37. www.sciencedirect.com www.sciencedirect.com
    Stress response mechanisms in protein misfolding diseases: Profiling a cellular model of Huntington's disease
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      DOI: 10.1016/j.abb.2023.109711

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    sciencedirect.com/science/article/pii/S0003986123002102
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    Lgr5-expressing secretory cells form a Wnt inhibitory niche in cartilage critical for chondrocyte identity
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      DOI: 10.1016/j.stem.2023.08.004

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    sciencedirect.com/science/article/pii/S1934590923002874
  39. Aug 2023
  40. www.sciencedirect.com www.sciencedirect.com
    Functional analogs of mammalian 4E-BPs reveal a role for TOR in global plant translation
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      DOI: 10.1016/j.celrep.2023.112892

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    sciencedirect.com/science/article/pii/S2211124723009038
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    DPPA3-HIF1α axis controls colorectal cancer chemoresistance by imposing a slow cell-cycle phenotype
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      DOI: 10.1016/j.celrep.2023.112927

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    sciencedirect.com/science/article/pii/S2211124723009385
  42. Jul 2023
  43. www.sciencedirect.com www.sciencedirect.com
    Disruption of neuronal RHEB signaling impairs oligodendrocyte differentiation and myelination through mTORC1-DLK1 axis
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      DOI: 10.1016/j.celrep.2023.112801

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    sciencedirect.com/science/article/pii/S2211124723008124
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    The kinesin Kif21b regulates radial migration of cortical projection neurons through a non-canonical function on actin cytoskeleton
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      DOI: 10.1016/j.celrep.2023.112744

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    sciencedirect.com/science/article/pii/S2211124723007556
  45. Jun 2023
  46. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Deneddylating enzyme SENP8 regulates neuronal development
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      DOI: 10.1111/jnc.15797

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    onlinelibrary.wiley.com/doi/10.1111/jnc.15797
  47. May 2023
  48. www.sciencedirect.com www.sciencedirect.com
    Mitochondrial Bcl-xL promotes brain synaptogenesis by controlling non-lethal caspase activation
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      DOI: 10.1016/j.isci.2023.106674

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    sciencedirect.com/science/article/pii/S2589004223007514
  49. www.sciencedirect.com www.sciencedirect.com
    Stress-induced perturbations in intracellular amino acids reprogram mRNA translation in osmoadaptation independently of the ISR
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      DOI: 10.1016/j.celrep.2022.111092

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    sciencedirect.com/science/article/pii/S2211124722008944
  50. Apr 2023
  51. link.springer.com link.springer.com
    Gut taste receptor type 1 member 3 is an intrinsic regulator of Western diet-induced intestinal inflammation
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      DOI: 10.1186/s12916-023-02848-0

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    link.springer.com/article/10.1186/s12916-023-02848-0
  52. www.sciencedirect.com www.sciencedirect.com
    Mitochondrial dynamics define muscle fiber type by modulating cellular metabolic pathways
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      DOI: 10.1016/j.celrep.2023.112434

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    sciencedirect.com/science/article/pii/S221112472300445X
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    Unidirectional and phase-gated signaling synchronizes murine presomitic mesoderm cells
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      DOI: 10.1016/j.devcel.2023.04.002

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      DOI: 10.1016/j.devcel.2023.04.002

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    sciencedirect.com/science/article/pii/S1534580723001557
  54. Mar 2023
  55. www.sciencedirect.com www.sciencedirect.com
    MAIT cells activate dendritic cells to promote TFH cell differentiation and induce humoral immunity
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      DOI: 10.1016/j.celrep.2023.112310

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    sciencedirect.com/science/article/pii/S2211124723003212
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FDA-approved Abl/EGFR/PDGFR kinase inhibitors show potent efficacy against pandemic and seasonal influenza A virus infections of human lung explants
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      DOI: 10.1016/j.isci.2023.106309

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    ncbi.nlm.nih.gov/pmc/articles/PMC10034449/
  57. www.mdpi.com www.mdpi.com
    NAADP-Evoked Ca2+ Signaling Leads to Mutant Huntingtin Aggregation and Autophagy Impairment in Murine Astrocytes
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      DOI: 10.3390/ijms24065593

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  58. Feb 2023
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    NRF3 activates mTORC1 arginine-dependently for cancer cell viability
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  60. Jan 2023
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    Human metastatic cholangiocarcinoma patient-derived xenografts and tumoroids for preclinical drug evaluation
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  62. www.sciencedirect.com www.sciencedirect.com
    Single-copy locus proteomics of early- and late-firing DNA replication origins identifies a role of Ask1/DASH complex in replication timing control
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  63. Dec 2022
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    A rapid RIG-I signaling relay mediates efficient antiviral response
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    Low-dose ganciclovir ameliorates dextran sulfate sodium-induced ulcerative colitis through inhibiting macrophage STING activation in mice
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    Molecular Indicators of Blood-Brain Barrier Breakdown and Neuronal Injury in Pregnancy Complicated by Fetal Growth Restriction
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  67. Nov 2022
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    Disrupted control of origin activation compromises genome integrity upon destabilization of Polε and dysfunction of the TRP53-CDKN1A/P21 axis
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    Multiple-low-dose therapy: effective killing of high-grade serous ovarian cancer cells with ATR and CHK1 inhibitors
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  70. Oct 2022
  71. www.nature.com www.nature.com
    Induction of the hepatic aryl hydrocarbon receptor by alcohol dysregulates autophagy and phospholipid metabolism via PPP2R2D
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  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Reduced B-cell antigenicity of Omicron lowers host serologic response
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    Two independent respiratory chains adapt OXPHOS performance to glycolytic switch
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  74. Aug 2022
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    APOE4 drives inflammation in human astrocytes via TAGLN3 repression and NF-κB activation
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  76. Jul 2022
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    HMCES modulates the transcriptional regulation of nodal/activin and BMP signaling in mESCs
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  78. Apr 2022
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    The mitochondrial pyruvate carrier regulates memory T cell differentiation and antitumor function
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    The Arabidopsis F-box protein FBW2 targets AGO1 for degradation to prevent spurious loading of illegitimate small RNA
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    GFPT2/GFAT2 and AMDHD2 act in tandem to control the hexosamine pathway
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  82. Feb 2022
  83. www.sciencedirect.com www.sciencedirect.com
    CASCADE: high-throughput characterization of regulatory complex binding altered by non-coding variants
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  84. Dec 2021
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    IFI16 inhibits DNA repair that potentiates type-I interferon-induced antitumor effects in triple negative breast cancer
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  86. Nov 2021
  87. www.mdpi.com www.mdpi.com
    O-GlcNAcylation Inhibits Endocytosis of Amyloid Precursor Protein by Decreasing Its Localization in Lipid Raft Microdomains
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  88. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  89. Oct 2021
  90. www.sciencedirect.com www.sciencedirect.com
    Human skeletal muscle CD90+ fibro-adipogenic progenitors are associated with muscle degeneration in type 2 diabetic patients
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    Replication catastrophe is responsible for intrinsic PAR glycohydrolase inhibitor-sensitivity in patient-derived ovarian cancer models
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      DOI: 10.1186/s13046-021-02124-0

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    PI3Kδ coordinates transcriptional, chromatin, and metabolic changes to promote effector CD8+ T cells at the expense of central memory
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    CWI pathway participated in vegetative growth and pathogenicity through a downstream effector AflRlm1 in Aspergillus flavus
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    PIWI-mediated control of tissue-specific transposons is essential for somatic cell differentiation
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    Nitrate signaling promotes plant growth by upregulating gibberellin biosynthesis and destabilization of DELLA proteins
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  96. Sep 2021
  97. www.nature.com www.nature.com
    Brain adiponectin signaling controls peripheral insulin response in Drosophila
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    Overexpression of α-synuclein inhibits mitochondrial Ca2+ trafficking between the endoplasmic reticulum and mitochondria through MAMs by altering the GRP75–IP3R interaction
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    SCIMP is a spatiotemporal transmembrane scaffold for Erk1/2 to direct pro-inflammatory signaling in TLR-activated macrophages
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  100. Aug 2021
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    HIV-1 Nef interacts with the cyclin K/CDK13 complex to antagonize SERINC5 for optimal viral infectivity
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    miR-1 coordinately regulates lysosomal v-ATPase and biogenesis to impact proteotoxicity and muscle function during aging
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  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  104. www.cell.com www.cell.com
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  106. Jul 2021
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    COVID-19 vaccine mRNA-1273 elicits a protective immune profile in mice that is not associated with vaccine-enhanced disease upon SARS-CoV-2 challenge
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    Cavin3 released from caveolae interacts with BRCA1 to regulate the cellular stress response
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    Retrofusion of intralumenal MVB membranes parallels viral infection and coexists with exosome release
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  111. Jun 2021
  112. www.nature.com www.nature.com
    A versatile reverse genetics platform for SARS-CoV-2 and other positive-strand RNA viruses
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  113. www.sciencedirect.com www.sciencedirect.com
    Secreted gelsolin inhibits DNGR-1-dependent cross-presentation and cancer immunity
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      DOI: 10.1016/j.cell.2021.05.021

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  114. May 2021
  115. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Mechanical overload-induced muscle-derived extracellular vesicles promote adipose tissue lipolysis
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      DOI: 10.1096/fj.202100242R

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  116. www.sciencedirect.com www.sciencedirect.com
    Axonal generation of amyloid-β from palmitoylated APP in mitochondria-associated endoplasmic reticulum membranes
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      DOI: 10.1016/j.celrep.2021.109134

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    Timer-based proteomic profiling of the ubiquitin-proteasome system reveals a substrate receptor of the GID ubiquitin ligase
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  118. www.sciencedirect.com www.sciencedirect.com
    Actin-Membrane Release Initiates Cell Protrusions
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  119. Apr 2021
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    Scribble sub-cellular localization modulates recruitment of YES1 to regulate YAP1 phosphorylation
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  121. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CDKN2A Deletion in Melanoma Excludes T Cell Infiltration by Repressing Chemokine Expression in a Cell Cycle-Dependent Manner
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      DOI: 10.3389/fonc.2021.641077

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  122. www.jneurosci.org www.jneurosci.org
    Pathogenic GRM7 mutations associated with neurodevelopmental disorders impair axon outgrowth and presynaptic terminal development
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  123. www.nature.com www.nature.com
    Neddylation is required for presynaptic clustering of mGlu7 and maturation of presynaptic terminals
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      DOI: 10.1038/s12276-021-00585-z

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  124. Feb 2021
  125. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Differential expression of five prosomatostatin genes in the central nervous system of the catshark Scyliorhinus canicula
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      DOI: 10.1002/cne.24898

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    onlinelibrary.wiley.com/doi/10.1002/cne.24898
  126. Jan 2021
  127. www.sciencedirect.com www.sciencedirect.com
    The ER-embedded UBE2J1/RNF26 ubiquitylation complex exerts spatiotemporal control over the endolysosomal pathway
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  128. Dec 2020
  129. www.sciencedirect.com www.sciencedirect.com
    Exosomal miR-193a and let-7g accelerate cancer progression on primary colorectal cancer and paired peritoneal metastatic cancer
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  130. www.sciencedirect.com www.sciencedirect.com
    Gut Microbiota Composition Modulates the Magnitude and Quality of Germinal Centers during Plasmodium Infections
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  131. www.sciencedirect.com www.sciencedirect.com
    Human VAPome Analysis Reveals MOSPD1 and MOSPD3 as Membrane Contact Site Proteins Interacting with FFAT-Related FFNT Motifs
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  132. Nov 2020
  133. onlinelibrary.wiley.com onlinelibrary.wiley.com
    An epilepsy‐associated ACTL6B variant captures neuronal hyperexcitability in a human induced pluripotent stem cell model
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      DOI: 10.1002/jnr.24747

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  134. Oct 2020
  135. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Tau phosphorylation by glycogen synthase kinase 3β modulates AChE expression
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      DOI: 10.1111/jnc.15189

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  136. Sep 2020
  137. www.eneuro.org www.eneuro.org
    Grp94 regulates the recruitment of aneural AChR clusters for the assembly of postsynaptic specializations by modulating ADF/cofilin activity and turnover
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      DOI: 10.1523/ENEURO.0025-20.2020

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  138. www.sciencedirect.com www.sciencedirect.com
    11q Deletion or ALK Activity Curbs DLG2 Expression to Maintain an Undifferentiated State in Neuroblastoma
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      DOI: 10.1016/j.celrep.2020.108171

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    sciencedirect.com/science/article/pii/S2211124720311608
  139. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Type I interferon underlies severe disease associated with Junín virus infection in mice
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      DOI: 10.7554/eLife.55352

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  140. www.sciencedirect.com www.sciencedirect.com
    Wdr47 Controls Neuronal Polarization through the Camsap Family Microtubule Minus-End-Binding Proteins
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      DOI: 10.1016/j.celrep.2020.107526

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  141. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    N‐linked glycosylation of the mGlu7 receptor regulates the forward trafficking and transsynaptic interaction with Elfn1
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      DOI: 10.1096/fj.202001544R

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  142. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Docosahexaenoic acid protection against palmitic acid‐induced lipotoxicity in NGF differentiated PC12 cells involves enhancement of autophagy and inhibition of apoptosis and necroptosis
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      DOI: 10.1111/jnc.15038

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  143. www.sciencedirect.com www.sciencedirect.com
    A Switch in p53 Dynamics Marks Cells That Escape from DSB-Induced Cell Cycle Arrest
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      DOI: 10.1016/j.celrep.2020.107995

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  144. www.sciencedirect.com www.sciencedirect.com
    Functional and Evolutionary Diversification of Otx2 and Crx in Vertebrate Retinal Photoreceptor and Bipolar Cell Development
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      DOI: 10.1016/j.celrep.2019.12.072

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  145. Jan 2020
  146. www.sciencedirect.com www.sciencedirect.com
    In Vivo Protein Complementation Demonstrates Presynaptic α-Synuclein Oligomerization and Age-Dependent Accumulation of 8–16-mer Oligomer Species
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      DOI: 10.1016/j.celrep.2019.10.089

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  147. www.sciencedirect.com www.sciencedirect.com
    Time-Resolved Small RNA Sequencing Unravels the Molecular Principles of MicroRNA Homeostasis
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      DOI: 10.1016/j.molcel.2019.06.018

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  148. bmcbiol.biomedcentral.com bmcbiol.biomedcentral.com
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      DOI: 10.1186/s12915-018-0616-2

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  149. www.sciencedirect.com www.sciencedirect.com
    foxF-1 Controls Specification of Non-body Wall Muscle and Phagocytic Cells in Planarians
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      DOI: 10.1016/j.cub.2018.10.030

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  150. Nov 2018
  151. www.sciencedirect.com www.sciencedirect.com
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  152. www.sciencedirect.com www.sciencedirect.com
    POLE3-POLE4 Is a Histone H3-H4 Chaperone that Maintains Chromatin Integrity during DNA Replication
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  153. www.sciencedirect.com www.sciencedirect.com
    Polε Instability Drives Replication Stress, Abnormal Development, and Tumorigenesis
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  154. www.sciencedirect.com www.sciencedirect.com
    A C9orf72 ALS/FTD Ortholog Acts in Endolysosomal Degradation and Lysosomal Homeostasis
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  155. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Stabilization of Reversed Replication Forks by Telomerase Drives Telomere Catastrophe
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  156. www.sciencedirect.com www.sciencedirect.com
    A Distinct Class of Genome Rearrangements Driven by Heterologous Recombination
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  157. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  158. Nov 2017
  159. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Overexpression of α‐synuclein in an astrocyte cell line promotes autophagy inhibition and apoptosis
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  160. www.sciencedirect.com www.sciencedirect.com
    Transcription-Replication Conflict Orientation Modulates R-Loop Levels and Activates Distinct DNA Damage Responses
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    Eye Absence Does Not Regulate Planarian Stem Cells during Eye Regeneration
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      (Thermo Fisher Scientific Cat# G-21040, RRID:AB_2536527)

      SciCrunch record: RRID:AB_2536527

      Alternate resolvers: SciCrunch xml N2T identifiers.org

      What is this?

      RRID:AB_2536527 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1534580717300710