47 Matching Annotations
  1. Nov 2025
  2. link.springer.com link.springer.com
    Attenuating α-synuclein pathology in mice with in situ engineered astrocytes
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    link.springer.com/article/10.1186/s40035-025-00518-0
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Fc-Modified IVIG with Enhanced Blood–Brain Barrier Penetration Ameliorates Cognitive Deficits and Neuropathology in A53T α-Synuclein Transgenic Mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC12618800/
  4. Sep 2025
  5. www.sciencedirect.com www.sciencedirect.com
    α-Synuclein aggregates inhibit ESCRT-III through sequestration and collateral degradation
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    sciencedirect.com/science/article/pii/S1097276525007075
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Low-density lipoprotein receptor–related protein 1 mediates α-synuclein transmission from the striatum to the substantia nigra in animal models of Parkinson’s disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC12407564/
  7. Jul 2025
  8. www.sciencedirect.com www.sciencedirect.com
    TNF-α-NF-κB activation through pathological α-Synuclein disrupts the BBB and exacerbates axonopathy
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    sciencedirect.com/science/article/pii/S2211124725007727
  9. www.eneuro.org www.eneuro.org
    SCD Inhibition Protects from α-Synuclein-Induced Neurotoxicity But Is Toxic to Early Neuron Cultures
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    eneuro.org/content/8/4/ENEURO.0166-21.2021
  10. Apr 2025
  11. www.jneurosci.org www.jneurosci.org
    Coronin1A regulates the trafficking of alpha synuclein in microglia
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    jneurosci.org/content/45/11/e1337242025
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Alpha-synuclein regulates nucleolar DNA double-strand break repair in melanoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC11980859/
  13. Mar 2025
  14. link.springer.com link.springer.com
    Proximity proteomics reveals unique and shared pathological features between multiple system atrophy and Parkinson’s disease
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    link.springer.com/article/10.1186/s40478-025-01958-5
  15. www.sciencedirect.com www.sciencedirect.com
    Single extracellular vesicle detection assay identifies membrane-associated α-synuclein as an early-stage biomarker in Parkinson’s disease
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    sciencedirect.com/science/article/pii/S2666379125000722
  16. Feb 2025
  17. www.sciencedirect.com www.sciencedirect.com
    Oligodendrocytes drive neuroinflammation and neurodegeneration in Parkinson’s disease via the prosaposin-GPR37-IL-6 axis
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    sciencedirect.com/science/article/pii/S2211124725000373
  18. Dec 2024
  19. 52.53.155.43 52.53.155.43
    PDF-html.html
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    52.53.155.43/a82bc61618bba92f8f86f30b899fd1de833883d0/PDF-html.html
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Protocol for generation of PD-modeling-induced neurons and detection of α-synuclein forms
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    pmc.ncbi.nlm.nih.gov/articles/PMC11609654/
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mitochondrial oxidant stress promotes α-synuclein aggregation and spreading in mice with mutated glucocerebrosidase
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    pmc.ncbi.nlm.nih.gov/articles/PMC11634889/
  22. Sep 2024
  23. www.biorxiv.org www.biorxiv.org
    Comparing alpha-synuclein-interactomes between multiple systems atrophy and Parkinson’s disease reveals unique and shared pathological features
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    biorxiv.org/content/10.1101/2024.09.20.613717v1
  24. May 2024
  25. www.sciencedirect.com www.sciencedirect.com
    Nuclear aggregates of NONO/SFPQ and A-to-I-edited RNA in Parkinson’s disease and dementia with Lewy bodies
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    sciencedirect.com/science/article/pii/S0896627324003283
  26. Apr 2024
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    In vivo bioluminescence imaging of the intracerebral fibroin-controlled AAV-α-synuclein diffusion for monitoring the central nervous system and peripheral expression
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11055870/
  28. www.nature.com www.nature.com
    Genetic and pharmacological reduction of CDK14 mitigates synucleinopathy
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    nature.com/articles/s41419-024-06534-8
  29. Mar 2024
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mutant α-synuclein causes death of human cortical neurons via ERK1/2 and JNK activation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10916047/
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    LRRK2 kinase inhibition reverses G2019S mutation-dependent effects on tau pathology progression
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    ncbi.nlm.nih.gov/pmc/articles/PMC10910783/
  32. Jan 2024
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Gut mucosal cells transfer α-synuclein to the vagus nerve
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    ncbi.nlm.nih.gov/pmc/articles/PMC10795834/
  34. Aug 2023
  35. www.biorxiv.org www.biorxiv.org
    Gut mucosal cells transfer α-synuclein to the vagus nerve
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    biorxiv.org/content/10.1101/2023.08.14.553305v1
  36. Mar 2023
  37. onlinelibrary.wiley.com onlinelibrary.wiley.com
    The effect of KTKEGV repeat motif and intervening ATVA sequence on α-synuclein solubility and assembly
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15763
  38. Nov 2022
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Parkinson’s disease-associated Leucine-rich repeat kinase regulates UNC-104-dependent axonal transport of Arl8-positive vesicles in Drosophila
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC9672966/
  40. academic.oup.com academic.oup.com
    GBA variant E326K is associated with alpha-synuclein aggregation and lipid droplet accumulation in human cell lines
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    academic.oup.com/hmg/advance-article/doi/10.1093/hmg/ddac233/6708353
  41. Aug 2022
  42. www.sciencedirect.com www.sciencedirect.com
    Alpha synuclein determines ferroptosis sensitivity in dopaminergic neurons via modulation of ether-phospholipid membrane composition
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    sciencedirect.com/science/article/pii/S2211124722010488
  43. May 2022
  44. www.sciencedirect.com www.sciencedirect.com
    Microparticle immunocapture assay for quantitation of protein multimer amount and size
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    sciencedirect.com/science/article/pii/S2667237522000777
  45. www.tandfonline.com www.tandfonline.com
    Reduction of the α-synuclein expression promotes slowing down early neuropathology development in the Drosophila model of Parkinson's disease
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    tandfonline.com/doi/abs/10.1080/01677063.2022.2064462
  46. Mar 2022
  47. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Acute inflammation down-regulates alpha-synuclein expression in enteric neurons
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    onlinelibrary.wiley.com/doi/10.1111/jnc.14656
  48. Jul 2021
  49. www.jneurosci.org www.jneurosci.org
    Untitled document
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    jneurosci.org/content/36/41/10510
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Monomeric Alpha-Synuclein Exerts a Physiological Role on Brain ATP Synthase
    4
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    ncbi.nlm.nih.gov/pmc/articles/PMC5059426/
  51. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Visualization of early oligomeric α-synuclein pathology and its impact on the dopaminergic system in the (Thy-1)-h[A30P]α-syn transgenic mouse model
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    onlinelibrary.wiley.com/doi/10.1002/jnr.24927
  52. May 2021
  53. www.sciencedirect.com www.sciencedirect.com
    α-Synuclein mutation impairs processing of endomembrane compartments and promotes exocytosis and seeding of α-synuclein pathology
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    sciencedirect.com/science/article/pii/S2211124721004332
  54. Mar 2021
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    α-Synuclein plasma membrane localization correlates with cellular phosphatidylinositol polyphosphate levels
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    ncbi.nlm.nih.gov/pmc/articles/PMC7929559/
  56. onlinelibrary.wiley.com onlinelibrary.wiley.com
    α‐Synuclein Abnormalities Trigger Focal Tau Pathology, Spreading to Various Brain Areas in Parkinson’s Disease
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15257
  57. Feb 2021
  58. onlinelibrary.wiley.com onlinelibrary.wiley.com
    α‐Synuclein evokes NLRP3 inflammasome‐mediated IL‐1β secretion from primary human microglia
    2
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    onlinelibrary.wiley.com/doi/10.1002/glia.23970
  59. Sep 2020
  60. www.jneurosci.org www.jneurosci.org
    Doublecortin like kinase 1 regulates α-Synuclein levels and toxicity
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    jneurosci.org/content/40/2/459
  61. Jan 2020
  62. www.sciencedirect.com www.sciencedirect.com
    Impairment of Macroautophagy in Dopamine Neurons Has Opposing Effects on Parkinsonian Pathology and Behavior
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    sciencedirect.com/science/article/pii/S2211124719312069
  63. www.sciencedirect.com www.sciencedirect.com
    The neuroprotective effect of fullerenols on a model of Parkinson’s disease in Drosophila melanogaster
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    sciencedirect.com/science/article/pii/S0006291X19324052
  64. www.sciencedirect.com www.sciencedirect.com
    Cytosolic Trapping of a Mitochondrial Heat Shock Protein Is an Early Pathological Event in Synucleinopathies
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    sciencedirect.com/science/article/pii/S2211124719307673
  65. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    sciencedirect.com/science/article/pii/S2211124719301330
  66. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Untitled document
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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.14656
  67. Nov 2018
  68. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    sciencedirect.com/science/article/pii/S0197018618300251