127 Matching Annotations
  1. Apr 2024
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    Nuclear RNA homeostasis promotes systems-level coordination of cell fate and senescence
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    sciencedirect.com/science/article/pii/S1934590924000961
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    H3K4me1 facilitates promoter-enhancer interactions and gene activation during embryonic stem cell differentiation
    1
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    sciencedirect.com/science/article/pii/S1097276524001710
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    SAFB restricts contact domain boundaries associated with L1 chimeric transcription
    1
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    sciencedirect.com/science/article/pii/S1097276524002314
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    EP300/CREBBP acetyltransferase inhibition limits steroid receptor and FOXA1 signaling in prostate cancer cells
    1
    1. scibot 10 Apr 2024
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      DOI: 10.1007/s00018-024-05209-z

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    link.springer.com/article/10.1007/s00018-024-05209-z
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    Defining a TFAP2C-centered transcription factor network during murine peri-implantation
    2
    1. scibot 04 Apr 2024
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    2. scibot 04 Apr 2024
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      DOI: 10.1016/j.devcel.2024.03.015

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    sciencedirect.com/science/article/pii/S1534580724001850
  7. Mar 2024
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    ARID1A orchestrates SWI/SNF-mediated sequential binding of transcription factors with ARID1A loss driving pre-memory B cell fate and lymphomagenesis
    1
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    sciencedirect.com/science/article/pii/S1535610824000540
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    The transcription factor NF-κB orchestrates nucleosome remodeling during the primary response to Toll-like receptor 4 signaling
    1
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      DOI: 10.1016/j.immuni.2024.02.004

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    sciencedirect.com/science/article/pii/S1074761324000803
  10. Feb 2024
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    EZH2 Inhibition Promotes Tumor Immunogenicity in Lung Squamous Cell Carcinomas
    1
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      DOI: 10.1158/2767-9764.CRC-23-0399

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    ncbi.nlm.nih.gov/pmc/articles/PMC10863487/
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    FOXA1 forms biomolecular condensates that unpack condensed chromatin to function as a pioneer factor
    1
    1. scibot 09 Feb 2024
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      DOI: 10.1016/j.molcel.2023.11.020

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    sciencedirect.com/science/article/abs/pii/S1097276523009656
  13. Jan 2024
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    DNA-guided transcription factor cooperativity shapes face and limb mesenchyme
    1
    1. scibot 23 Jan 2024
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    sciencedirect.com/science/article/pii/S0092867423014381
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    A SNAI2/CTCF Interaction is Required for NOTCH1 Expression in Rhabdomyosarcoma
    1
    1. scibot 05 Jan 2024
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      DOI: 10.1080/10985549.2023.2256640

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    ncbi.nlm.nih.gov/pmc/articles/PMC10761179/
  16. Dec 2023
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Adenovirus E1A binding to DCAF10 targets proteasomal degradation of RUVBL1/2 AAA+ ATPases required for quaternary assembly of multiprotein machines, innate immunity, and responses to metabolic stress
    1
    1. scibot 23 Dec 2023
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      DOI: 10.1128/jvi.00993-23

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    ncbi.nlm.nih.gov/pmc/articles/PMC10734532/
  18. Nov 2023
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    Epigenomic mapping reveals distinct B cell acute lymphoblastic leukemia chromatin architectures and regulators
    1
    1. scibot 22 Nov 2023
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      DOI: 10.1016/j.xgen.2023.100442

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    sciencedirect.com/science/article/pii/S2666979X2300277X
  20. journals.asm.org journals.asm.org
    Adenovirus E1A binding to DCAF10 targets proteasomal degradation of RUVBL1/2 AAA+ ATPases required for quaternary assembly of multiprotein machines, innate immunity, and responses to metabolic stress
    1
    1. scibot 18 Nov 2023
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      DOI: 10.1128/jvi.00993-23

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    journals.asm.org/doi/10.1128/jvi.00993-23
  21. Sep 2023
  22. www.sciencedirect.com www.sciencedirect.com
    RANK ligand converts the NCoR/HDAC3 co-repressor to a PGC1β- and RNA-dependent co-activator of osteoclast gene expression
    1
    1. scibot 30 Sep 2023
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      DOI: 10.1016/j.molcel.2023.08.029

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    sciencedirect.com/science/article/pii/S1097276523006937
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Stromal cells-specific retinoic acid determines parturition timing at single-cell and spatial-temporal resolution
    1
    1. scibot 20 Sep 2023
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      DOI: 10.1016/j.isci.2023.107796

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    ncbi.nlm.nih.gov/pmc/articles/PMC10502414/
  24. Aug 2023
  25. 52.53.155.43 52.53.155.43
    Loss of CtBP2 may be a mechanistic link between metabolic derangements and progressive impairment of pancreatic β cell function
    2
    1. scibot 18 Aug 2023
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      DOI: 10.1016/j.celrep.2023.112914

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    2. scibot 10 Aug 2023
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      DOI: 10.1016/j.celrep.2023.112914

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    52.53.155.43/464fcb14db36fa0ad68672734eea21dbff7f105c/PIIS2211124723009257-html.html
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    Chromatin accessibility in the Drosophila embryo is determined by transcription factor pioneering and enhancer activation
    1
    1. scibot 10 Aug 2023
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      DOI: 10.1016/j.devcel.2023.07.007

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    sciencedirect.com/science/article/pii/S1534580723003477
  27. Jul 2023
  28. www.sciencedirect.com www.sciencedirect.com
    Ketolysis drives CD8+ T cell effector function through effects on histone acetylation
    1
    1. scibot 29 Jul 2023
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      DOI: 10.1016/j.immuni.2023.07.002

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    sciencedirect.com/science/article/pii/S107476132300314X
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    Modeling epigenetic lesions that cause gliomas
    1
    1. scibot 27 Jul 2023
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      DOI: 10.1016/j.cell.2023.06.022

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    sciencedirect.com/science/article/abs/pii/S0092867423007298
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    Spatial and clonality-resolved 3D cancer genome alterations reveal enhancer-hijacking as a potential prognostic marker for colorectal cancer
    1
    1. scibot 15 Jul 2023
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      DOI: 10.1016/j.celrep.2023.112778

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    sciencedirect.com/science/article/pii/S2211124723007891
  31. Jun 2023
  32. www.sciencedirect.com www.sciencedirect.com
    Dnmt3bas coordinates transcriptional induction and alternative exon inclusion to promote catalytically active Dnmt3b expression
    1
    1. scibot 16 Jun 2023
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      DOI: 10.1016/j.celrep.2023.112587

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    sciencedirect.com/science/article/pii/S2211124723005983
  33. May 2023
  34. www.sciencedirect.com www.sciencedirect.com
    Impact of supraphysiologic MDM2 expression on chromatin networks and therapeutic responses in sarcoma
    1
    1. scibot 12 May 2023
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      DOI: 10.1016/j.xgen.2023.100321

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    sciencedirect.com/science/article/pii/S2666979X23000897
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    LKB1 controls inflammatory potential through CRTC2-dependent histone acetylation
    1
    1. scibot 12 May 2023
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    sciencedirect.com/science/article/pii/S1097276523002885
  36. Apr 2023
  37. www.sciencedirect.com www.sciencedirect.com
    Integrative dissection of gene regulatory elements at base resolution
    1
    1. scibot 29 Apr 2023
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      DOI: 10.1016/j.xgen.2023.100318

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    Escape from oncogene-induced senescence is controlled by POU2F2 and memorized by chromatin scars
    1
    1. scibot 06 Apr 2023
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      DOI: 10.1016/j.xgen.2023.100293

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  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    VGLL2-NCOA2 leverages developmental programs for pediatric sarcomagenesis
    1
    1. scibot 05 Apr 2023
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    ncbi.nlm.nih.gov/pmc/articles/PMC10054615/
  40. Mar 2023
  41. www.sciencedirect.com www.sciencedirect.com
    Structural elements promote architectural stripe formation and facilitate ultra-long-range gene regulation at a human disease locus
    1
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    sciencedirect.com/science/article/pii/S1097276523001661
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    KDM6A Loss Triggers an Epigenetic Switch That Disrupts Urothelial Differentiation and Drives Cell Proliferation in Bladder Cancer
    1
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      DOI: 10.1158/0008-5472.CAN-22-1444

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    ncbi.nlm.nih.gov/pmc/articles/PMC10015223/
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Acetylated HOXB13 Regulated Super Enhancer Genes Define Therapeutic Vulnerabilities of Castration-Resistant Prostate Cancer
    1
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      DOI: 10.1158/1078-0432.CCR-21-3603

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    ncbi.nlm.nih.gov/pmc/articles/PMC9481728/
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    Gene silencing dynamics are modulated by transiently active regulatory elements
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    sciencedirect.com/science/article/pii/S1097276523000850
  45. Jan 2023
  46. www.sciencedirect.com www.sciencedirect.com
    Multi-omics profiling visualizes dynamics of cardiac development and functions
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      DOI: 10.1016/j.celrep.2022.111891

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    sciencedirect.com/science/article/pii/S2211124722017909
  47. www.sciencedirect.com www.sciencedirect.com
    TRIM28 secures skeletal stem cell fate during skeletogenesis by silencing neural gene expression and repressing GREM1/AKT/mTOR signaling axis
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    sciencedirect.com/science/article/pii/S2211124723000232
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    Functional partitioning of transcriptional regulators by patterned charge blocks
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      DOI: 10.1016/j.cell.2022.12.013

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    sciencedirect.com/science/article/pii/S0092867422015264
  49. Dec 2022
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IL-1β expression driven by androgen receptor absence or inactivation promotes prostate cancer bone metastasis
    1
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      DOI: 10.1158/2767-9764.crc-22-0262

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    ncbi.nlm.nih.gov/pmc/articles/PMC9770512/
  51. aacrjournals.org aacrjournals.org
    IL-1β expression driven by androgen receptor absence or inactivation promotes prostate cancer bone metastasis
    1
    1. scibot 24 Dec 2022
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      DOI: 10.1158/2767-9764.CRC-22-0262

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    aacrjournals.org/cancerrescommun/article/2/12/1545/711358/IL1-Expression-Driven-by-Androgen-Receptor-Absence
  52. aacrjournals.org aacrjournals.org
    BAF complex maintains glioma stem cells in pediatric H3K27M-glioma
    1
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      DOI: 10.1158/2159-8290.CD-21-1491

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    aacrjournals.org/cancerdiscovery/article/12/12/2880/711164/BAF-Complex-Maintains-Glioma-Stem-Cells-in
  53. aacrjournals.org aacrjournals.org
    Loss of epigenetic regulation disrupts lineage integrity, induces aberrant alveogenesis and promotes breast cancer
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    1. scibot 03 Dec 2022
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      DOI: 10.1158/2159-8290.CD-21-0865

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    aacrjournals.org/cancerdiscovery/article/12/12/2930/711188/Loss-of-Epigenetic-Regulation-Disrupts-Lineage
  54. Oct 2022
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    Chromatin jets define the properties of cohesin-driven in vivo loop extrusion
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  56. Sep 2022
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    Tissue-specific Grb10/Ddc insulator drives allelic architecture for cardiac development
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    Global Chromatin Accessibility Profiling Analysis Reveals a Chronic Activation State in Aged Muscle Stem Cells
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  59. Aug 2022
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    SOX transcription factors direct TCF-independent WNT/β-catenin responsive transcription to govern cell fate in human pluripotent stem cells
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    DNA methyltransferase 3 alpha and TET methylcytosine dioxygenase 2 restrain mitochondrial DNA-mediated interferon signaling in macrophages
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    Oncofusion-driven de novo enhancer assembly promotes malignancy in Ewing sarcoma via aberrant expression of the stereociliary protein LOXHD1
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    Dnmt3a knockout in excitatory neurons impairs postnatal synapse maturation and increases the repressive histone modification H3K27me3
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    Alcohol induced increases in sperm Histone H3 lysine 4 trimethylation correlate with increased placental CTCF occupancy and altered developmental programming
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    dCas9 fusion to computer-designed PRC2 inhibitor reveals functional TATA box in distal promoter region
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  73. Feb 2022
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    EBF1 nuclear repositioning instructs chromatin refolding to promote therapy resistance in T leukemic cells
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  75. Jan 2022
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  78. Dec 2021
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    KDM6B promotes activation of the oncogenic CDK4/6-pRB-E2F pathway by maintaining enhancer activity in MYCN-amplified neuroblastoma
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    Lysophosphatidic acid shifts metabolic and transcriptional landscapes to induce a distinct cellular state in human pluripotent stem cells
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    A recurrent chromosomal inversion suffices for driving escape from oncogene-induced senescence via subTAD reorganization
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    Collective regulation of chromatin modifications predicts replication timing during cell cycle
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    TooManyPeaks identifies drug-resistant-specific regulatory elements from single-cell leukemic epigenomes
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    JAK inhibitors dampen activation of interferon-activated transcriptomes and the SARS-CoV-2 receptor ACE2 in human renal proximal tubules
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    Enhancer decommissioning imposes an epigenetic barrier to sensory hair cell regeneration
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    Distal Enhancer Potentiates Activin- and GnRH-Induced Transcription of FSHB
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  92. Jul 2021
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    Intron 1-Mediated Regulation of EGFR Expression In EGFR-Dependent Malignancies is Mediated by AP-1 and BET Proteins
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    PRDM16 Maintains Homeostasis of the Intestinal Epithelium by Controlling Region-Specific Metabolism
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  95. May 2021
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    FSHB Transcription is Regulated by a Novel 5’ Distal Enhancer with a Fertility-Associated Single Nucleotide Polymorphism
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    Temporal dissection of an enhancer cluster reveals distinct temporal and functional contributions of individual elements
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    Analysis of Genome Architecture during SCNT Reveals a Role of Cohesin in Impeding Minor ZGA
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    The Conserved Non-coding Sequences CNS6 and CNS9 Control Cytokine-Induced Rorc Transcription during T Helper 17 Cell Differentiation
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    Developmentally Programmed Tankyrase Activity Upregulates β-Catenin and Licenses Progression of Embryonic Genome Activation
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    Large-Scale Topological Changes Restrain Malignant Progression in Colorectal Cancer
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    Integrated Metabolic and Epigenomic Reprograming by H3K27M Mutations in Diffuse Intrinsic Pontine Gliomas
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    Impact of chromatin context on Cas9-induced DNA double-strand break repair pathway balance
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    Epigenomic tensor predicts disease subtypes and reveals constrained tumor evolution
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  107. Feb 2021
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    An optimized protocol for rapid, sensitive and robust on-bead ChIP-seq from primary cells
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    Pancreatic progenitor epigenome maps prioritize type 2 diabetes risk genes with roles in development
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    ARID1A Mutations Promote P300-Dependent Endometrial Invasion through Super-Enhancer Hyperacetylation
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    NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency
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    Histone Variant and Cell Context Determine H3K27M Reprogramming of the Enhancer Landscape and Oncogenic State
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    The Leukemogenic TCF3-HLF Complex Rewires Enhancers Driving Cellular Identity and Self-Renewal Conferring EP300 Vulnerability
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    HUMAN TROPHOBLAST DIFFERENTIATION IS ASSOCIATED WITH PROFOUND GENE REGULATORY AND EPIGENETIC CHANGES
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    A C19MC-LIN28A-MYCN Oncogenic Circuit Driven by Hijacked Super-enhancers Is a Distinct Therapeutic Vulnerability in ETMRs: A Lethal Brain Tumor
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    FOXA2 Is Required for Enhancer Priming during Pancreatic Differentiation
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    Recapitulation and Reversal of Schizophrenia-Related Phenotypes in Setd1a-Deficient Mice
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    Oncogenic Notch Promotes Long-Range Regulatory Interactions within Hyperconnected 3D Cliques
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    Widespread Enhancer Dememorization and Promoter Priming during Parental-to-Zygotic Transition
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  141. Nov 2018
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    Targeting Epigenetic Crosstalk as a Therapeutic Strategy for EZH2-Aberrant Solid Tumors
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    Increased Lactate Secretion by Cancer Cells Sustains Non-cell-autonomous Adaptive Resistance to MET and EGFR Targeted Therapies
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    Combinatorial CRISPR/Cas9 Approach to Elucidate a Far-Upstream Enhancer Complex for Tissue-Specific Sox9 Expression
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    AMPK/FIS1-Mediated Mitophagy Is Required for Self-Renewal of Human AML Stem Cells
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    Lineage-Determining Transcription Factor TCF-1 Initiates the Epigenetic Identity of T Cells
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    SETD7 Drives Cardiac Lineage Commitment through Stage-Specific Transcriptional Activation
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    Warming Induces Significant Reprogramming of Beige, but Not Brown, Adipocyte Cellular Identity
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    The Adenovirus E1A C Terminus Suppresses a Delayed Antiviral Response and Modulates RAS Signaling
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    Dual Targeting of Oncogenic Activation and Inflammatory Signaling Increases Therapeutic Efficacy in Myeloproliferative Neoplasms
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    Type 2 Diabetes Variants Disrupt Function of SLC16A11 through Two Distinct Mechanisms
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      AB_2561016

      Curator: @chewbeccax

      Resource used:

      (Active Motif Cat# 39133, RRID:AB_2561016)

      SciCrunch record: RRID:AB_2561016

      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:AB_2561016 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0092867417306943
  157. www.sciencedirect.com www.sciencedirect.com
    Mll3 and Mll4 Facilitate Enhancer RNA Synthesis and Transcription from Promoters Independently of H3K4 Monomethylation
    1
    1. scibot 08 Nov 2017
      AB_2561016

      Curator: @ifroman

      Resource used:

      (Active Motif Cat# 39133, RRID:AB_2561016)

      SciCrunch record: RRID:AB_2561016

      Alternate resolvers: SciCrunch xml N2T identifiers.org

      What is this?

      RRID:AB_2561016 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1097276517302745
  158. www.sciencedirect.com www.sciencedirect.com
    Transcriptional Dependencies in Diffuse Intrinsic Pontine Glioma
    1
    1. scibot 08 Nov 2017
      AB_2561016

      Curator: @gabimpine

      Resource used:

      (Active Motif Cat# 39133, RRID:AB_2561016)

      SciCrunch record: RRID:AB_2561016

      Alternate resolvers: SciCrunch xml N2T identifiers.org

      What is this?

      RRID:AB_2561016 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1535610817301071
  159. www.sciencedirect.com www.sciencedirect.com
    Metazoan Nuclear Pores Provide a Scaffold for Poised Genes and Mediate Induced Enhancer-Promoter Contacts
    1
    1. scibot 08 Nov 2017
      AB_2561016

      Curator: @gabimpine

      Resource used:

      (Active Motif Cat# 39133, RRID:AB_2561016)

      SciCrunch record: RRID:AB_2561016

      Alternate resolvers: SciCrunch xml N2T identifiers.org

      What is this?

      RRID:AB_2561016 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1097276517301351
  160. www.sciencedirect.com www.sciencedirect.com
    Resolving Heart Regeneration by Replacement Histone Profiling
    1
    1. scibot 08 Nov 2017
      39133

      Curator: @Zeljana_Babic

      Resource used:

      (Active Motif Cat# 39133, RRID:AB_2561016)

      SciCrunch record: RRID:AB_2561016

      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:AB_2561016 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S1534580717300400
  161. www.sciencedirect.com www.sciencedirect.com
    Adaptive Chromatin Remodeling Drives Glioblastoma Stem Cell Plasticity and Drug Tolerance
    1
    1. scibot 08 Nov 2017
      AB_2561016

      Resource used:

      (Active Motif Cat# 39133, RRID:AB_2561016)

      SciCrunch record: RRID:AB_2561016

      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:AB_2561016
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    sciencedirect.com/science/article/pii/S193459091630399X
  162. www.sciencedirect.com www.sciencedirect.com
    RNA Binding to CBP Stimulates Histone Acetylation and Transcription
    1
    1. scibot 08 Nov 2017
      AB_2561016

      Curator: @gabimpine

      Resource used:

      (Active Motif Cat# 39133, RRID:AB_2561016)

      SciCrunch record: RRID:AB_2561016

      Alternate resolvers: SciCrunch xml N2T identifiers.org

      What is this?

      RRID:AB_2561016 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0092867416317366
  163. www.sciencedirect.com www.sciencedirect.com
    Histone Acetylome-wide Association Study of Autism Spectrum Disorder
    1
    1. scibot 08 Nov 2017
      AB_2561016

      Curator: @gabimpine

      Resource used:

      (Active Motif Cat# 39133, RRID:AB_2561016)

      SciCrunch record: RRID:AB_2561016

      Alternate resolvers: SciCrunch xml N2T identifiers.org

      What is this?

      RRID:AB_2561016 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0092867416314519