109 Matching Annotations
  1. Last 7 days
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    Chromatin state dynamics of autosomes and the B chromosome during spermatogenesis in Pseudococcus viburni
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    nature.com/articles/s41437-025-00800-x
  3. Oct 2025
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    PHF19 drives the formation of PRC2 clusters to enhance motility in TNBC cells
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    sciencedirect.com/science/article/pii/S2211124725011623
  5. Sep 2025
  6. www.biorxiv.org www.biorxiv.org
    Metabolic Crossroads: AMDHD2 Couples the Hexosamine Biosynthetic Pathway to Acetyl-CoA Homeostasis in Pluripotent Stem Cells
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    biorxiv.org/content/10.1101/2025.08.20.671247v1
  7. Jul 2025
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    Mitotic slippage causes nuclear instability in polyploid cells
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    biorxiv.org/content/10.1101/2025.07.21.665898v1
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    β-catenin functions as a molecular adapter for disordered cBAF interactions
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    sciencedirect.com/science/article/pii/S1097276525005763
  10. Jun 2025
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    Identifying the target, mechanism, and agonist of α-ketoglutaric acid in delaying mesenchymal stem cell senescence
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    sciencedirect.com/science/article/pii/S2211124725006886
  12. Dec 2024
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    Interchromosomal contacts between regulatory regions trigger stable transgenerational epigenetic inheritance in Drosophila
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    sciencedirect.com/science/article/pii/S1097276524009468
  14. Oct 2024
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    The chromodomain protein CDYL confers forebrain identity to human cortical organoids by inhibiting neuronatin
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    sciencedirect.com/science/article/pii/S2211124724011653
  16. Sep 2024
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    Activation of automethylated PRC2 by dimerization on chromatin
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    Dynamic phosphorylation of FOXA1 by Aurora B guides post-mitotic gene reactivation
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    Promoter DNA methylation and transcription factor condensation are linked to transcriptional memory in mammalian cells
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    sciencedirect.com/science/article/pii/S2405471224002370
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    TGF-β and RAS jointly unmask primed enhancers to drive metastasis
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    GABAergic neuronal lineage development determines clinically actionable targets in diffuse hemispheric glioma, H3G34-mutant
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    sciencedirect.com/science/article/pii/S1535610824003052
  22. Aug 2024
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comprehensive Target Engagement by the EZH2 Inhibitor Tulmimetostat Allows for Targeting of ARID1A Mutant Cancers
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    ncbi.nlm.nih.gov/pmc/articles/PMC11292196/
  24. Jul 2024
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    CircARAP2 controls sMICA-induced NK cell desensitization by erasing CTCF/PRC2-induced suppression in early endosome marker RAB5A
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    link.springer.com/article/10.1007/s00018-024-05285-1
  26. 52.53.155.43 52.53.155.43
    Matrix stiffness aggravates osteoarthritis progression through H3K27me3 demethylation induced by mitochondrial damage
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  27. May 2024
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    A chromatin code for limb segment identity in axolotl limb regeneration
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  29. Apr 2024
  30. www.cell.com www.cell.com
    Nuclear RNA homeostasis promotes systems-level coordination of cell fate and senescence
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    cell.com/cell-stem-cell/fulltext/S1934-5909(24)00096-1
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    An RNA-dependent and phase-separated active subnuclear compartment safeguards repressive chromatin domains
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    Intervention with metabolites emulating endogenous cell transitions accelerates muscle regeneration in young and aged mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC10983034/
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    Modular dual-color BiAD sensors for locus-specific readout of epigenome modifications in single cells
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  34. Mar 2024
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    Epigenomic tomography for probing spatially defined chromatin state in the brain
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    ApoE maintains neuronal integrity via miRNA and H3K27me3-mediated repression.
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    Synthetic reversed sequences reveal default genomic states
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    nature.com/articles/s41586-024-07128-2
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    SWI/SNF-dependent genes are defined by their chromatin landscape
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  39. Feb 2024
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PCID2 dysregulates transcription and viral RNA processing to promote HIV-1 latency
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    Denaturing purifications demonstrate that PRC2 and other widely reported chromatin proteins do not appear to bind directly to RNA in vivo
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    EZH2 Inhibition Promotes Tumor Immunogenicity in Lung Squamous Cell Carcinomas
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    Targeting of H19/cell adhesion molecules circuitry by GSK-J4 epidrug inhibits metastatic progression in prostate cancer
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    cancerci.biomedcentral.com/articles/10.1186/s12935-024-03231-6
  44. Jan 2024
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    XIST directly regulates X-linked and autosomal genes in naive human pluripotent cells
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  46. Dec 2023
  47. www.biorxiv.org www.biorxiv.org
    Stem cell quiescence requires PRC2/PRC1-mediated mitochondrial checkpoint
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    biorxiv.org/content/10.1101/2021.04.21.440825v1
  48. Oct 2023
  49. www.embopress.org www.embopress.org
    Epigenetic regulation limits competence of pluripotent stem cell-derived oocytes
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    embopress.org/doi/10.15252/embj.2023113955
  50. Sep 2023
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    Perturbations in 3D genome organization can promote acquired drug resistance
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  52. Aug 2023
  53. www.embopress.org www.embopress.org
    Lineage commitment of dermal fibroblast progenitors is controlled by Kdm6b-mediated chromatin demethylation
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    embopress.org/doi/10.15252/embj.2023113880
  54. 52.53.155.43 52.53.155.43
    Loss of CtBP2 may be a mechanistic link between metabolic derangements and progressive impairment of pancreatic β cell function
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  55. Jun 2023
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    DNA hypomethylation silences anti-tumor immune genes in early prostate cancer and CTCs
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  57. May 2023
  58. www.cell.com www.cell.com
    Lactobacillus plantarum-derived indole-3-lactic acid ameliorates colorectal tumorigenesis via epigenetic regulation of CD8+ T cell immunity
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    cell.com/cell-metabolism/fulltext/S1550-4131(23)00141-9
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    Bidirectional regulation of postmitotic H3K27me3 distributions underlie cerebellar granule neuron maturation dynamics
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    ncbi.nlm.nih.gov/pmc/articles/PMC10181825/
  60. Apr 2023
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    Integrative dissection of gene regulatory elements at base resolution
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    sciencedirect.com/science/article/pii/S2666979X23000861
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    A hyper-quiescent chromatin state formed during aging is reversed by regeneration
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    Evolutionarily distinct and sperm-specific supersized chromatin loops are marked by Helitron transposons in Xenopus tropicalis
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    sciencedirect.com/science/article/pii/S2211124723001626
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    Lineage Commitment of Dermal Fibroblast Progenitors is Mediated by Chromatin De-Repression
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    ncbi.nlm.nih.gov/pmc/articles/PMC10028926/
  65. Feb 2023
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    Bat pluripotent stem cells reveal unusual entanglement between host and viruses
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    sciencedirect.com/science/article/pii/S0092867423000417
  67. Jan 2023
  68. www.cell.com www.cell.com
    Glucose dissociates DDX21 dimers to regulate mRNA splicing and tissue differentiation
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    cell.com/cell/fulltext/S0092-8674(22)01517-3
  69. Dec 2022
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Antifungal mechanisms of silver nanoparticles on mycotoxin producing rice false smut fungus
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    ncbi.nlm.nih.gov/pmc/articles/PMC9793317/
  71. aacrjournals.org aacrjournals.org
    BAF complex maintains glioma stem cells in pediatric H3K27M-glioma
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    aacrjournals.org/cancerdiscovery/article/12/12/2880/711164/BAF-Complex-Maintains-Glioma-Stem-Cells-in
  72. Oct 2022
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Prdm14 promotes mouse ESC self-renewal and PGCLC specification through enhancement of Stat3 activity
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    ncbi.nlm.nih.gov/pmc/articles/PMC9589213/
  74. May 2022
  75. www.sciencedirect.com www.sciencedirect.com
    Nde1 is required for heterochromatin compaction and stability in neocortical neurons
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    sciencedirect.com/science/article/pii/S2589004222006253
  76. Apr 2022
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    L3MBTL2-mediated CGA transcriptional suppression promotes pancreatic cancer progression through modulating autophagy
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  78. Mar 2022
  79. www.sciencedirect.com www.sciencedirect.com
    The BTB transcription factors ZBTB11 and ZFP131 maintain pluripotency by repressing pro-differentiation genes
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    sciencedirect.com/science/article/pii/S2211124722002601
  80. www.sciencedirect.com www.sciencedirect.com
    dCas9 fusion to computer-designed PRC2 inhibitor reveals functional TATA box in distal promoter region
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    sciencedirect.com/science/article/pii/S221112472200184X
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    An Inducible CRISPR/Cas9 Screen Identifies DTX2 as a Transcriptional Regulator of Human Telomerase
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  82. Feb 2022
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    Interferons reshape the 3D conformation and accessibility of macrophage chromatin
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  84. Jan 2022
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    Establishment of developmental gene silencing by ordered polycomb complex recruitment in early zebrafish embryos
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    ncbi.nlm.nih.gov/pmc/articles/PMC8769650/
  86. Dec 2021
  87. elifesciences.org elifesciences.org
    5-Hydroxymethylcytosine-mediated active demethylation is required for mammalian neuronal differentiation and function
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    elifesciences.org/articles/66973
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    Distal and proximal cis-regulatory elements sense X chromosome dosage and developmental state at the Xist locus
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  89. Nov 2021
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    A recurrent chromosomal inversion suffices for driving escape from oncogene-induced senescence via subTAD reorganization
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  91. Oct 2021
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    NR4A1 regulates expression of immediate early genes, suppressing replication stress in cancer
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  93. Aug 2021
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    Evidence of pioneer factor activity of an oncogenic fusion transcription factor
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    Enhancer decommissioning imposes an epigenetic barrier to sensory hair cell regeneration
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    Hyper-Editing of Cell-Cycle Regulatory and Tumor Suppressor RNA Promotes Malignant Progenitor Propagation
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  98. Jul 2021
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    N6-methyladenine DNA Modification in Glioblastoma
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  100. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An Adversarial DNA N6-Methyladenine-Sensor Network Preserves Polycomb Silencing
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    ncbi.nlm.nih.gov/pmc/articles/PMC6591016/
  101. mcr.aacrjournals.org mcr.aacrjournals.org
    An IFNγ/STAT1/JMJD3 Axis Induces ZEB1 Expression and Promotes Aggressiveness in Lung Adenocarcinoma
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    mcr.aacrjournals.org/content/19/7/1234
  102. Jun 2021
  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SIRT1 regulates sphingolipid metabolism and neural differentiation of mouse embryonic stem cells through c-Myc-SMPDL3B
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    ncbi.nlm.nih.gov/pmc/articles/PMC8216717/
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    H3K27 demethylases are dispensable for activation of Polycomb-regulated injury response genes in peripheral nerve.
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  105. May 2021
  106. academic.oup.com academic.oup.com
    FSHB Transcription is Regulated by a Novel 5’ Distal Enhancer with a Fertility-Associated Single Nucleotide Polymorphism
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    academic.oup.com/endo/article/162/1/bqaa181/5917511
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    Functional Interplay between Histone H2B ADP-Ribosylation and Phosphorylation Controls Adipogenesis
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    Stromal SOX2 Upregulation Promotes Tumorigenesis through the Generation of a SFRP1/2-Expressing Cancer-Associated Fibroblast Population
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  109. Apr 2021
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    Integrated Metabolic and Epigenomic Reprograming by H3K27M Mutations in Diffuse Intrinsic Pontine Gliomas
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    Impact of chromatin context on Cas9-induced DNA double-strand break repair pathway balance
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    ncbi.nlm.nih.gov/pmc/articles/PMC8153251/
  112. Mar 2021
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    H3.3-K27M drives neural stem cell-specific gliomagenesis in a human iPSC-derived model
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  114. Dec 2020
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    Epigenomic Reprogramming toward Mesenchymal-Epithelial Transition in Ovarian-Cancer-Associated Mesenchymal Stem Cells Drives Metastasis
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  116. Nov 2020
  117. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ARID1A loss in adult hepatocytes activates β-catenin-mediated erythropoietin transcription
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    ncbi.nlm.nih.gov/pmc/articles/PMC7641585/
  118. Sep 2020
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    4D Genome Rewiring during Oncogene-Induced and Replicative Senescence
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    Genome-wide kinetic properties of transcriptional bursting in mouse embryonic stem cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC7299619/
  121. Jan 2020
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    PDGFR-β Signaling Regulates Cardiomyocyte Proliferation and Myocardial Regeneration
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    Nucleome Dynamics during Retinal Development
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    DEAD-Box Helicase 18 Counteracts PRC2 to Safeguard Ribosomal DNA in Pluripotency Regulation
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    Histone Variant and Cell Context Determine H3K27M Reprogramming of the Enhancer Landscape and Oncogenic State
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    Genomic Resolution of DLX-Orchestrated Transcriptional Circuits Driving Development of Forebrain GABAergic Neurons
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    Heterozygous Mutations in SMARCA2 Reprogram the Enhancer Landscape by Global Retargeting of SMARCA4
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    ncbi.nlm.nih.gov/pmc/articles/PMC7291823/
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