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Activating an interleukin 4-FLT3-STAT6 axis in multipotent progenitors restores lymphopoiesis in inflammation and aging

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1. scibot 30 May 2026
  
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  DOI: 10.1016/j.immuni.2026.04.018
  
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sciencedirect.com/science/article/pii/S1074761326001809
May 2026
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A longitudinal atlas of human psoriatic skin reveals the mechanisms of anti-IL-23 therapy in disrupting the type 17 inflammatory circuit

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1. scibot 29 May 2026
  
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Uncovering spatially resolved functional genomics with CRISPR screen sequencing

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1. scibot 29 May 2026
  
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  DOI: 10.1016/j.cell.2026.04.049
  
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Ablation of the adhesion G protein-coupled receptor ADGRL1 activates anti-tumor immune response via cDC1-T cell hub formation

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1. scibot 27 May 2026
  
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A ketogenesis-ferroptosis axis maintains leukemic stem cell survival and leukemia progression

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1. scibot 12 May 2026
  
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sciencedirect.com/science/article/pii/S1934590926001530
Apr 2026
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Optineurin modulates mTORC2/AKT/STAT3 signaling to control MHC class II expression and adaptive immunity against HSV-1

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The weight-loss-independent hepatoprotective benefits of semaglutide are orchestrated by intrahepatic sinusoidal endothelial GLP-1 receptors

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1. scibot 16 Apr 2026
  
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sciencedirect.com/science/article/pii/S1550413126001051
Mar 2026
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A hierarchical Rorc(γt) cis-regulatory cascade orchestrates differentiation of RORγt⁺ innate immune cells

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1. scibot 26 Mar 2026
  
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Feb 2026
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Efficacy and safety of autologous CD5-KO anti-CD5 CAR-T cells in relapsed/refractory CD5+ hematological malignancies

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1. scibot 03 Feb 2026
  
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sciencedirect.com/science/article/pii/S2666379126000017
Jan 2026
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METTL3/CD98-mediated glutamate efflux in CAFs drives CD8+ T cell exhaustion and impedes neoadjuvant immunochemotherapy

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1. scibot 29 Jan 2026
  
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  DOI: 10.1016/j.celrep.2026.116933
  
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sciencedirect.com/science/article/pii/S2211124726000112
Dec 2025
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Glycolysis maintains effector function of lung Th17 TRM cells in precision cut lung slices

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1. scibot 19 Dec 2025
  
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  DOI: 10.1016/j.isci.2025.114051
  
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Gut microbiota promotes immune tolerance at the maternal-fetal interface

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1. scibot 18 Dec 2025
  
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  DOI: 10.1016/j.cell.2025.11.022
  
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The TCR-SUB1-DOCK2 axis promotes autoimmunity by driving pathogenic CD4+ T cell tissue infiltration

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1. scibot 11 Dec 2025
  
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  DOI: 10.1016/j.immuni.2025.11.009
  
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sciencedirect.com:5037/science/article/pii/S1074761325005114
Nov 2025
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Fatty acids modulate the colorectal cancer immune microenvironment via regulating the interaction and transactivation of PPARα/δ and P53

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1. scibot 29 Nov 2025
  
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  DOI: 10.1016/j.celrep.2025.116623
  
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Virus envelope glycoprotein targeting bispecific T cell engager protects mice from lethal severe fever with thrombocytopenia virus infection

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1. scibot 22 Nov 2025
  
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  DOI: 10.1016/j.xcrm.2025.102458
  
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1-s2.0-S2589004225023120-main-html.html

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1. scibot 15 Nov 2025
  
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Noradrenergic control of bone marrow and thymus by AgRP neurons is impaired in experimental multiple sclerosis

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1. scibot 13 Nov 2025
  
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  DOI: 10.1016/j.celrep.2025.116556
  
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Cancer-associated adipocytes mediate CD8+T cell dysfunction via FGF21-driven lipolysis

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1. scibot 05 Nov 2025
  
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  DOI: 10.1016/j.celrep.2025.116526
  
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sciencedirect.com/science/article/pii/S2211124725012975
Oct 2025
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TET2-mutant clonal hematopoiesis enhances macrophage antigen presentation and improves immune checkpoint therapy in solid tumors

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1. scibot 18 Oct 2025
  
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  DOI: 10.1016/j.ccell.2025.09.011
  
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Liver microbial DNA signatures and extracellular vesicle epitopes as predictors of post-hepatectomy liver failure

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  DOI: 10.1016/j.isci.2025.113618
  
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Vorapaxar enhanced mitochondria-associated ferroptosis primes cancer immunotherapy via targeting FOXO1/HMOX1 axis

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pmc.ncbi.nlm.nih.gov/articles/PMC12629800/
Sep 2025
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Safe immunosuppression-resistant pan-cancer immunotherapeutics by velcro-like density-dependent targeting of tumor-associated carbohydrate antigens

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Aug 2025
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1-s2.0-S2589004225010338-main-html.html

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1. scibot 12 Aug 2025
  
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Jul 2025
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Gasdermin-D-mediated epithelial-immune circuit synchronizes nutrient absorption and host defense in the small intestine

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1. scibot 25 Jul 2025
  
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  DOI: 10.1016/j.immuni.2025.06.019
  
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CINTER-seq: Chemical profiling reveals interaction-dependent cell landscapes and gene signatures in vivo

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1. scibot 17 Jul 2025
  
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  DOI: 10.1016/j.immuni.2025.06.011
  
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Jun 2025
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A hypomorphic Il2rb mutant mouse model recapitulates and reveals mechanisms of human T cell immune dysregulation in IL-2Rβ deficiency

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1. scibot 26 Jun 2025
  
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  DOI: 10.1016/j.celrep.2025.115902
  
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MET pathway inhibition increases chemo-immunotherapy efficacy in small cell lung cancer

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  DOI: 10.1016/j.xcrm.2025.102194
  
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May 2025
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Maternal natural killer cells drive neuroimmune disorders in offspring through aberrant secretion of extracellular granzyme B

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Overcoming NK-mediated rejection by anti-3rd-party central memory veto CD8 T cells through downregulation of DNAM-1 on alloreactive NK cells

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Apr 2025
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KIF26B promotes bladder cancer progression via activating Wnt/β-catenin signaling in a TRAF2-dependent pathway

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Rorγt-positive dendritic cells are required for the induction of peripheral regulatory T cells in response to oral antigens

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  DOI: 10.1016/j.cell.2025.03.020
  
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Mar 2025
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Translation dysregulation in cancer as a source for targetable antigens

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  DOI: 10.1016/j.ccell.2025.03.003
  
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The Nuclear Receptor NR1B1/RARα Arrests the Differentiation of Anti-Tumor Effector Cytotoxic T Cells

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1. scibot 13 Mar 2025
  
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  DOI: 10.1002/advs.202410241
  
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advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202410241
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The polyamine-regulating enzyme SSAT1 impairs tissue regulatory T cell function in chronic cutaneous inflammation

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1. scibot 04 Mar 2025
  
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  DOI: 10.1016/j.immuni.2025.02.011
  
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Feb 2025
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CV1-secreting sCAR-T cells potentiate the abscopal effect of microwave ablation in heterogeneous tumors

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1. scibot 20 Feb 2025
  
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  DOI: 10.1016/j.xcrm.2025.101965
  
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BPS Publications

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  DOI: 10.1111/bph.17344
  
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Phenotypic plasticity and increased infiltration of peripheral blood-derived TREM1+ mono-macrophages following radiotherapy in rectal cancer

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Mechanical Force-Induced cGAS Activation in Carcinoma Cells Facilitates Splenocytes into Liver to Drive Metastasis

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Nucleo-cytosolic acetyl-CoA drives tumor immune evasion by regulating PD-L1 in melanoma

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A High-Content Screen Identifies Drugs That Restrict Tumor Cell Extravasation across the Endothelial Barrier

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Blocking cGAS-STING pathway promotes post-stroke functional recovery in an extended treatment window via facilitating remyelination

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Adipose stem cells control obesity-induced T cell infiltration into adipose tissue

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Low-dose Decitabine enhances the efficacy of viral cancer vaccines for immunotherapy.

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Maternal inflammation regulates fetal emergency myelopoiesis

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Structure-guided engineering of immunotherapies targeting TRBC1 and TRBC2 in T cell malignancies

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Revealing splenectomy-driven microRNA hsa-7b-5p’s role in pancreatic cancer progression

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Leukaemia exposure alters the transcriptional profile and function of BCR::ABL1 negative macrophages in the bone marrow niche

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Tumor-secreted FGF21 acts as an immune suppressor by rewiring cholesterol metabolism of CD8+T cells

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Discovery of galectin-8 as an LILRB4 ligand driving M-MDSCs defines a class of antibodies to fight solid tumors

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Apoptosis releases hydrogen sulfide to inhibit Th17 cell differentiation

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Lipid accumulation-mediated histone hypoacetylation drives persistent NK cell dysfunction in anti-tumor immunity

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Enhancing CAR T-cell Therapy Using Fab-Based Constitutively Heterodimeric Cytokine Receptors

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A CSF-1R-blocking antibody/IL-10 fusion protein increases anti-tumor immunity by effectuating tumor-resident CD8+ T cells

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Loss of CD4+ T cell-intrinsic arginase 1 accelerates Th1 response kinetics and reduces lung pathology during influenza infection

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A genetic method specifically delineates Th1-type Treg cells and their roles in tumor immunity

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Enhanced bypass of PD-L1 translation reduces the therapeutic response to mTOR kinase inhibitors

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Rebalancing liver-infiltrating CCR3+ and CD206+ monocytes improves diet-induced NAFLD

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Vectored immunoprophylaxis and treatment of SARS-CoV-2 infection in a preclinical model

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Mar 2023
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Hematopoietic stem cells preferentially traffic misfolded proteins to aggresomes and depend on aggrephagy to maintain protein homeostasis

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Feb 2023
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TNFR2+ regulatory T cells protect against bacteremic pneumococcal pneumonia by suppressing IL-17A-producing γδ T cells in the lung

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The loss of epithelial Smad4 drives immune evasion via CXCL1 while displaying vulnerability to combinatorial immunotherapy in gastric cancer

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Protocol to assess the antitumor efficacy of an immunotherapeutic peptide in syngeneic orthotopic glioma mouse models

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Lymphatic vessels in bone support regeneration after injury

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Targeting Menin disrupts the KMT2A/B and polycomb balance to paradoxically activate bivalent genes

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MHC class II-restricted antigen presentation is required to prevent dysfunction of cytotoxic T cells by blood-borne myeloids in brain tumors

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METTL16 drives leukemogenesis and leukemia stem cell self-renewal by reprogramming BCAA metabolism

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Nov 2022
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Cancer immunotherapies transition endothelial cells into HEVs that generate TCF1+ T lymphocyte niches through a feed-forward loop

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Oct 2022
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Cbl-b Restrains Priming of Pathogenic Th17 Cells via the Inhibition of IL-6 Production by Macrophages

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Sep 2022
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IRE1α overexpression in malignant cells limits tumor progression by inducing an anti-cancer immune response

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  DOI: 10.1080/2162402X.2022.2116844
  
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Lung fibroblasts facilitate pre-metastatic niche formation by remodeling the local immune microenvironment

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Nanocarriers based on bacterial membrane materials for cancer vaccine delivery

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  DOI: 10.1038/s41596-022-00713-7
  
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Tumor cells dictate anti-tumor immune responses by altering pyruvate utilization and succinate signaling in CD8+ T cells

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Amino acid catabolism regulates hematopoietic stem cell proteostasis via a GCN2-eIF2α axis

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Viral infection engenders bona fide and bystander subsets of lung-resident memory B cells through a permissive mechanism

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Unravelling the sex-specific diversity and functions of adrenal gland macrophages

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Poroptosis: a form of cell death depending on plasma membrane nanopores formation

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Maladaptive innate immune training of myelopoiesis links inflammatory comorbidities

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ILC precursors differentiate into metabolically distinct ILC1-like cells during Mycobacterium tuberculosis infection

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Type 1 innate lymphoid cells regulate the onset of Toxoplasma gondii-induced neuroinflammation

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Lactylation-driven METTL3-mediated RNA m6A modification promotes immunosuppression of tumor-infiltrating myeloid cells

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Notch-mediated lactate metabolism regulates MDSC development through the Hes1/MCT2/c-Jun axis

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Interferon gamma constrains type 2 lymphocyte niche boundaries during mixed inflammation

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Macrophages transfer mitochondria to sensory neurons to resolve inflammatory pain

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Myeloid cell subsets that express latency-associated peptide promote cancer growth by modulating T cells

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Indoleamine 2,3-dioxygenase 1 is essential for sustaining durable antibody responses

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A non-classical monocyte-derived macrophage subset provides a splenic replication niche for intracellular Salmonella

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MTHFD2 is a metabolic checkpoint controlling effector and regulatory T cell fate and function

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Arthritis flares mediated by tissue-resident memory T cells in the joint

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BPS Publications

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  DOI: 10.1111/bph.15652
  
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Cognate recognition of microbial antigens defines constricted CD4+ T cell receptor repertoires in the inflamed colon

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A TLR7 antagonist restricts interferon-dependent and -independent immunopathology in a mouse model of severe influenza

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Methods for Studying Mouse and Human Invariant Natural Killer T Cells

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B19-VLPs as an effective delivery system for tumour antigens to induce humoral and cellular immune responses against triple negative breast cancer

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Redundant cytokine requirement for intestinal microbiota-induced Th17 cell differentiation in draining lymph nodes

1
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Hsf1 promotes hematopoietic stem cell fitness and proteostasis in response to ex vivo culture stress and aging

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Untitled document

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Invariant natural killer T cells coordinate removal of senescent cells

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  DOI: 10.1016/j.medj.2021.04.014
  
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A hotspot mutation in transcription factor IKZF3 drives B cell neoplasia via transcriptional dysregulation

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  DOI: 10.1016/j.ccell.2021.02.003
  
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Increased stem cell proliferation in atherosclerosis accelerates clonal hematopoiesis

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  DOI: 10.1016/j.cell.2021.01.049
  
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Direct Tumor Killing and Immunotherapy through Anti-SerpinB9 Therapy

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IL-17A Activated by Toll-Like Receptor 9 Contributes to Development of Septic Acute Kidney Injury

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  DOI: 10.1152/ajprenal.00313.2019
  
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Dec 2020
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BPS Publications

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  DOI: 10.1111/bph.15216
  
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Visualization of T Cell Migration in the Spleen Reveals a Network of Perivascular Pathways that Guide Entry into T Zones

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CD137 Signaling Regulates Acute Colitis via RALDH2-Expressing CD11b−CD103+ DCs

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CD49a Regulates Cutaneous Resident Memory CD8+ T Cell Persistence and Response

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  DOI: 10.1016/j.celrep.2020.108085
  
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ADORA1 Inhibition Promotes Tumor Immune Evasion by Regulating the ATF3-PD-L1 Axis

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  DOI: 10.1016/j.ccell.2020.02.006
  
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Neutrophil elastase triggers the development of autoimmune diabetes by exacerbating innate immune responses in pancreatic islets of non-obese diabetic mice

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  DOI: 10.1042/CS20200021
  
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The Cardiac Microenvironment Instructs Divergent Monocyte Fates and Functions in Myocarditis

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An Evolutionarily Conserved Function of Polycomb Silences the MHC Class I Antigen Presentation Pathway and Enables Immune Evasion in Cancer

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  DOI: 10.1016/j.ccell.2019.08.008
  
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Cancer-Cell-Intrinsic cGAS Expression Mediates Tumor Immunogenicity

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NIX-Mediated Mitophagy Promotes Effector Memory Formation in Antigen-Specific CD8+ T Cells

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Untitled document

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  DOI: 10.1016/j.immuni.2019.01.021
  
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Lung γδ T Cells Mediate Protective Responses during Neonatal Influenza Infection that Are Associated with Type 2 Immunity

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Untitled document

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Large-Scale Clonal Analysis Resolves Aging of the Mouse Hematopoietic Stem Cell Compartment

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Epigenetic Memory Underlies Cell-Autonomous Heterogeneous Behavior of Hematopoietic Stem Cells

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Epigenetic Memory Underlies Cell-Autonomous Heterogeneous Behavior of Hematopoietic Stem Cells

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