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MHC-II-restricted neoantigen vaccine reverses immune microenvironment and overcomes resistance to immune-checkpoint inhibitors in cold tumors

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1. scibot 29 Nov 2025
  
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  DOI: 10.1016/j.medj.2025.100936
  
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sciencedirect.com:5037/science/article/pii/S2666634025003630
Oct 2025
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CD169+ macrophages identify and eliminate tumor cells in colorectal cancer through CD169/CD43 interaction and FasL-driven apoptosis

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1. scibot 01 Oct 2025
  
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  DOI: 10.1016/j.celrep.2025.116351
  
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sciencedirect.com/science/article/pii/S2211124725011222
Jul 2025
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Macropinocytosis maintains CAF subtype identity under metabolic stress in pancreatic cancer

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1. scibot 25 Jul 2025
  
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  DOI: 10.1016/j.ccell.2025.06.021
  
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sciencedirect.com/science/article/pii/S1535610825002715
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CINTER-seq: Chemical profiling reveals interaction-dependent cell landscapes and gene signatures in vivo

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1. scibot 17 Jul 2025
  
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  DOI: 10.1016/j.immuni.2025.06.011
  
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sciencedirect.com/science/article/pii/S1074761325002808
Jun 2025
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Non-canonical PRC1.1 licenses transcriptional response to enable Treg plasticity in immune adaptation

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1. scibot 17 Jun 2025
  
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  DOI: 10.1016/j.molcel.2025.05.029
  
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sciencedirect.com/science/article/pii/S109727652500468X
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An mRNA vaccine encoding the SARS-CoV-2 Omicron XBB.1.5 receptor-binding domain protects mice from the JN.1 variant

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1. scibot 11 Jun 2025
  
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  DOI: 10.1016/j.ebiom.2025.105794
  
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sciencedirect.com/science/article/pii/S2352396425002385
May 2025
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Trajectories of macrophage ontogeny and reprogramming in cancer

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1. scibot 18 May 2025
  
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  DOI: 10.1016/j.isci.2025.112498
  
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sciencedirect.com/science/article/pii/S258900422500759X
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Activation of the endoplasmic reticulum stress regulator IRE1α compromises pulmonary host defenses

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1. scibot 16 May 2025
  
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  DOI: 10.1016/j.celrep.2025.115632
  
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sciencedirect.com/science/article/pii/S2211124725004036
Mar 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Pathway-instructed therapeutic selection of ruxolitinib reduces neuroinflammation in fungal postinfectious inflammatory syndrome

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1. scibot 27 Mar 2025
  
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  DOI: 10.1126/sciadv.adi9885
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11927619/
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Pathway-instructed therapeutic selection of ruxolitinib reduces neuroinflammation in fungal postinfectious inflammatory syndrome

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1. scibot 24 Mar 2025
  
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  DOI: 10.1126/sciadv.adi9885
  
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science.org/doi/10.1126/sciadv.adi9885
Aug 2024
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Released bacterial ATP shapes local and systemic inflammation during abdominal sepsis

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1. scibot 23 Aug 2024
  
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  DOI: 10.7554/eLife.96678
  
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2. scibot 23 Aug 2024
  
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  DOI: 10.7554/eLife.96678
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11335348/
Jul 2024
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Splenic marginal zone B cells restrict Mycobacterium tuberculosis infection by shaping the cytokine pattern and cell-mediated immunity

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1. scibot 19 Jul 2024
  
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  DOI: 10.1016/j.celrep.2024.114426
  
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sciencedirect.com/science/article/pii/S2211124724007551
www.cell.com www.cell.com

Anti-tumor efficacy of HRS-4642 and its potential combination with proteasome inhibition in KRAS G12D-mutant cancer

1
1. scibot 18 Jul 2024
  
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  RRID:AB_2562039
  
  DOI: 10.1016/j.ccell.2024.06.001
  
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cell.com/cancer-cell/abstract/S1535-6108(24)00226-5
May 2024
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DHCR24 inhibitor SH42 increases desmosterol without preventing atherosclerosis development in mice

1
1. scibot 23 May 2024
  
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  DOI: 10.1016/j.isci.2024.109830
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11103367/
Apr 2024
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Transcription factor Tox2 is required for metabolic adaptation and tissue residency of ILC3 in the gut

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1. scibot 30 Apr 2024
  
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  DOI: 10.1016/j.immuni.2024.04.001
  
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sciencedirect.com/science/article/pii/S1074761324002061
Feb 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Preoperative Immune Checkpoint Inhibition and Cryoablation in Early-Stage Breast Cancer

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1. scibot 11 Feb 2024
  
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  DOI: 10.1016/j.isci.2024.108880
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10850740/
Oct 2023
www.biorxiv.org www.biorxiv.org

CCR5 promotes the migration of CD8+ T cells to the leishmanial lesions

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1. scibot 24 Oct 2023
  
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  RRID:AB_2562039
  
  DOI: 10.1101/2023.10.10.561700
  
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biorxiv.org/content/10.1101/2023.10.10.561700v1
Apr 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

cDC1 coordinate innate and adaptive responses in the omentum required for T cell priming and memory

1
1. scibot 05 Apr 2023
  
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  RRID:AB_2562039
  
  DOI: 10.1126/sciimmunol.abq7432
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9835709/
Feb 2023
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IDH2 and TET2 mutations synergize to modulate T Follicular Helper cell functional interactionwith the AITL microenvironment

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1. scibot 03 Feb 2023
  
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  DOI: 10.1016/j.ccell.2023.01.003
  
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sciencedirect.com/science/article/pii/S153561082300003X
Dec 2022
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Splicing factor deficits render hematopoietic stem and progenitor cells sensitive to STAT3 inhibition

1
1. scibot 18 Dec 2022
  
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  DOI: 10.1016/j.celrep.2022.111825
  
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sciencedirect.com/science/article/pii/S221112472201717X
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Mucosal exposure to non-tuberculous mycobacteria elicits B cell-mediated immunity against pulmonary tuberculosis

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1. scibot 18 Dec 2022
  
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  DOI: 10.1016/j.celrep.2022.111783
  
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sciencedirect.com/science/article/pii/S2211124722016710
Nov 2022
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Engineered human cytokine/antibody fusion proteins expand regulatory T cells and confer autoimmune disease protection

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1. scibot 05 Nov 2022
  
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  DOI: 10.1016/j.celrep.2022.111478
  
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sciencedirect.com/science/article/pii/S2211124722013286
Jul 2022
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mTORC1 signaling in antigen-presenting cells of the skin restrains CD8+ T cell priming

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1. scibot 06 Jul 2022
  
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  DOI: 10.1016/j.celrep.2022.111032
  
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sciencedirect.com/science/article/pii/S2211124722008269
May 2022
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Lymph node colonization induces tumor-immune tolerance to promote distant metastasis

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1. scibot 12 May 2022
  
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  DOI: 10.1016/j.cell.2022.04.019
  
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sciencedirect.com/science/article/pii/S0092867422004664
Dec 2021
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AMP-activated protein kinase alpha1 promotes tumor development via FOXP3 elevation in tumor-infiltrating Treg cells

1
1. scibot 21 Dec 2021
  
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  DOI: 10.1016/j.isci.2021.103570
  
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sciencedirect.com/science/article/pii/S2589004221015406
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Cysteine 253 of UCP1 regulates energy expenditure and sex-dependent adipose tissue inflammation

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1. scibot 07 Dec 2021
  
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sciencedirect.com/science/article/pii/S1550413121005313
Jul 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Ketogenic diet restrains aging-induced exacerbation of coronavirus infection in mice

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1. scibot 08 Jul 2021
  
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  DOI: 10.7554/eLife.66522
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8245129/
May 2021
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Intestinal barrier dysfunction plays an integral role in arthritis pathology and can be targeted to ameliorate disease

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1. scibot 14 May 2021
  
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  DOI: 10.1016/j.medj.2021.04.013
  
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sciencedirect.com/science/article/pii/S2666634021001628
Apr 2021
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Staphylococcus cohnii is a potentially biotherapeutic skin commensal alleviating skin inflammation

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1. scibot 28 Apr 2021
  
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  DOI: 10.1016/j.celrep.2021.109052
  
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sciencedirect.com/science/article/pii/S2211124721003685
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A distal Foxp3 enhancer enables interleukin-2 dependent thymic Treg cell lineage commitment for robust immune tolerance

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1. scibot 10 Apr 2021
  
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  DOI: 10.1016/j.immuni.2021.03.020
  
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sciencedirect.com/science/article/pii/S1074761321001321
Mar 2021
elifesciences.org elifesciences.org

Enhancing mitochondrial activity in neurons protects against neurodegeneration in a mouse model of multiple sclerosis

1
1. scibot 28 Mar 2021
  
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  DOI: 10.7554/eLife.61798
  
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elifesciences.org/articles/61798
Jan 2021
physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com

Biological sex, not reproductive cycle, influences peripheral blood immune cell prevalence in mice

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1. scibot 26 Jan 2021
  
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  DOI: 10.1113/JP280637
  
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physoc.onlinelibrary.wiley.com/doi/10.1113/JP280637
Sep 2020
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Altered Immunity of Laboratory Mice in the Natural Environment Is Associated with Fungal Colonization

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1. scibot 23 Sep 2020
  
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  DOI: 10.1016/j.chom.2020.02.015
  
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sciencedirect.com/science/article/pii/S1931312820301232
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Microbiota-Derived Metabolites Suppress Arthritis by Amplifying Aryl-Hydrocarbon Receptor Activation in Regulatory B Cells

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1. scibot 23 Sep 2020
  
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  DOI: 10.1016/j.cmet.2020.03.003
  
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sciencedirect.com/science/article/pii/S1550413120301182
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Bacteria-Induced Group 2 Innate Lymphoid Cells in the Stomach Provide Immune Protection through Induction of IgA

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1. scibot 16 Sep 2020
  
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  DOI: 10.1016/j.immuni.2020.03.002
  
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Characterization of Resident Corneal Plasmacytoid Dendritic Cells and Their Pivotal Role in Herpes Simplex Keratitis

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  DOI: 10.1016/j.celrep.2020.108099
  
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Rewilding Nod2 and Atg16l1 Mutant Mice Uncovers Genetic and Environmental Contributions to Microbial Responses and Immune Cell Composition

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  DOI: 10.1016/j.chom.2020.03.001
  
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cell.com/cell-host-microbe/fulltext/S1931-3128(20)30124-4
Jan 2020
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Aging Induces an Nlrp3 Inflammasome-Dependent Expansion of Adipose B Cells That Impairs Metabolic Homeostasis

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  DOI: 10.1016/j.cmet.2019.10.006
  
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Aryl Hydrocarbon Receptor Contributes to the Transcriptional Program of IL-10-Producing Regulatory B Cells

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.celrep.2019.10.018
  
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Untitled document

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  DOI: 10.1016/j.immuni.2019.03.014
  
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Nov 2018
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Synthetic Lethal and Convergent Biological Effects of Cancer-Associated Spliceosomal Gene Mutations

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Dichotomous Expression of TNF Superfamily Ligands on Antigen-Presenting Cells Controls Post-priming Anti-viral CD4+ T Cell Immunity

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