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Engineered bacterial outer membrane vesicle vaccine prevents T cell exhaustion for antibacterial immunotherapy

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1. scibot 16 Sep 2026
  
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  DOI: 10.1016/j.celrep.2026.117954
  
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sciencedirect.com/science/article/pii/S2211124726010326
Apr 2026
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Human immune aging clock identifies RUNX1 as a decelerator of T cell senescence

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1. scibot 16 Apr 2026
  
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  DOI: 10.1016/j.immuni.2026.02.007
  
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sciencedirect.com/science/article/pii/S1074761326000774
Jan 2026
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Armored macrophage-targeted CAR-T cells reset and reprogram the tumor microenvironment and control metastatic cancer growth

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1. scibot 23 Jan 2026
  
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  DOI: 10.1016/j.ccell.2025.12.021
  
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sciencedirect.com/science/article/pii/S1535610825005550
Nov 2025
www.sciencedirect.com:5037 www.sciencedirect.com:5037

MHC-II-restricted neoantigen vaccine reverses immune microenvironment and overcomes resistance to immune-checkpoint inhibitors in cold tumors

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1. scibot 29 Nov 2025
  
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  DOI: 10.1016/j.medj.2025.100936
  
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sciencedirect.com:5037/science/article/pii/S2666634025003630
Aug 2025
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Engineered T cells stimulate dendritic cell recruitment and antigen spreading for potent anti-tumor immunity

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1. scibot 26 Aug 2025
  
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  DOI: 10.1016/j.xcrm.2025.102307
  
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sciencedirect.com/science/article/pii/S2666379125003805
Jun 2025
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Fc-optimized anti-CTLA-4 antibodies increase tumor-associated high endothelial venules and sensitize refractory tumors to PD-1 blockade

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1. scibot 04 Jun 2025
  
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  DOI: 10.1016/j.xcrm.2025.102141
  
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sciencedirect.com/science/article/pii/S2666379125002149
Mar 2025
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KLRG1 re-defines a leukemic clone of CD8 effector T cells sensitive to PI3K inhibitor in T cell large granular lymphocytic leukemia

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1. scibot 29 Mar 2025
  
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  DOI: 10.1016/j.xcrm.2025.102036
  
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sciencedirect.com/science/article/pii/S2666379125001090
Jan 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Syngeneic natural killer cell therapy activates dendritic and T cells in metastatic lungs and effectively treats low-burden metastases

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1. scibot 23 Jan 2025
  
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  DOI: 10.7554/eLife.99010
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11750138/
Aug 2024
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Blockade of LAG-3 and PD-1 leads to co-expression of cytotoxic and exhaustion gene modules in CD8+ T cells to promote antitumor immunity

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1. scibot 20 Aug 2024
  
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  AB_2562195
  
  DOI: 10.1016/j.cell.2024.06.036
  
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sciencedirect.com/science/article/pii/S0092867424007104
May 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

PPARα Agonism Enhances Immune Response to Radiotherapy while Dietary Oleic Acid Results in Counteraction

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1. scibot 03 May 2024
  
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  DOI: 10.1158/1078-0432.CCR-23-3433
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11061609/
Nov 2023
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Mice with FVB-derived sequence on chromosome 17 succumb to disseminated virus infection due to aberrant NK cell and T cell responses

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1. scibot 18 Nov 2023
  
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  RRID:AB_2562195
  
  DOI: 10.1016/j.isci.2023.108348
  
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sciencedirect.com/science/article/pii/S2589004223024252
Aug 2023
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Transplantation elicits a clonally diverse CD8+ T cell response that is comprised of potent CD43+ effectors

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1. scibot 17 Aug 2023
  
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  DOI: 10.1016/j.celrep.2023.112993
  
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sciencedirect.com/science/article/pii/S2211124723010045
Jun 2023
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Taxanes trigger cancer cell killing in vivo by inducing non-canonical T cell cytotoxicity

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1. scibot 16 Jun 2023
  
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  RRID:AB_2562195
  
  DOI: 10.1016/j.ccell.2023.05.009
  
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sciencedirect.com/science/article/pii/S1535610823001769
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Quantitative control of Ets1 dosage by a multi-enhancer hub promotes Th1 cell differentiation and protects from allergic inflammation

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1. scibot 01 Jun 2023
  
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  RRID:AB_2562195
  
  DOI: 10.1016/j.immuni.2023.05.004
  
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sciencedirect.com/science/article/pii/S1074761323002212
Nov 2022
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Re-purposing the pro-senescence properties of doxorubicin to introduce immunotherapy in breast cancer brain metastasis

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1. scibot 16 Nov 2022
  
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  RRID:AB_2562195
  
  DOI: 10.1016/j.xcrm.2022.100821
  
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sciencedirect.com/science/article/pii/S2666379122003809
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The transcription factor IRF2 drives interferon-mediated CD8+ T cell exhaustion to restrict anti-tumor immunity

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1. scibot 15 Nov 2022
  
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  RRID:AB_2562195
  
  DOI: 10.1016/j.immuni.2022.10.020
  
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sciencedirect.com/science/article/pii/S1074761322005611
Jul 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Increased Expression of Multiple Co-Inhibitory Molecules on Malaria-Induced CD8+ T Cells Are Associated With Increased Function Instead of Exhaustion

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1. scibot 27 Jul 2022
  
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  RRID:AB_2562195
  
  DOI: 10.3389/fimmu.2022.878320
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9301332/
May 2022
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Lymph node colonization induces tumor-immune tolerance to promote distant metastasis

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1. scibot 12 May 2022
  
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  RRID:AB_2562195
  
  DOI: 10.1016/j.cell.2022.04.019
  
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sciencedirect.com/science/article/pii/S0092867422004664
Apr 2021
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity

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1. scibot 24 Apr 2021
  
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  DOI: 10.1016/j.cell.2020.11.009
  
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pmc.ncbi.nlm.nih.gov/articles/PMC8064125/
Feb 2021
www.cell.com www.cell.com

Hematopoietic Progenitor Kinase1 (HPK1) Mediates T Cell Dysfunction and Is a Druggable Target for T Cell-Based Immunotherapies

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1. scibot 27 Feb 2021
  
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  RRID:AB_2562195
  
  DOI: 10.1016/j.ccell.2020.08.001
  
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cell.com/cancer-cell/abstract/S1535-6108(20)30375-5
Sep 2020
elifesciences.org elifesciences.org

IL-21/type I interferon interplay regulates neutrophil-dependent innate immune responses to Staphylococcus aureus

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1. scibot 23 Sep 2020
  
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  DOI: 10.7554/eLife.45501
  
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elifesciences.org/articles/45501
Jan 2020
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UVB-Induced Tumor Heterogeneity Diminishes Immune Response in Melanoma

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.cell.2019.08.032
  
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sciencedirect.com/science/article/pii/S0092867419309511
www.cell.com www.cell.com

Re-education of Tumor-Associated Macrophages by CXCR2 Blockade Drives Senescence and Tumor Inhibition in Advanced Prostate Cancer

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.celrep.2019.07.068
  
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cell.com/cell-reports/fulltext/S2211-1247(19)30972-6
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

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1. scibot 13 Jan 2020
  
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  RRID:AB_2562195
  
  DOI: 10.7554/eLife.45501
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6504231/
Nov 2017
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Modulation of let-7 miRNAs controls the differentiation of effector CD8 T cells

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1. scibot 08 Nov 2017
  
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  Curator: @patriciaelyse_
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5550279/