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HDAC10 promotes Th17 differentiation and IL-17A-driven neutrophilic airway inflammation in severe asthma

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1. scibot 03 Jul 2026
  
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sciencedirect.com/science/article/pii/S2211124726006881
May 2026
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IRF7 controls spontaneous autoimmune germinal center and plasma cell checkpoints

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1. scibot 30 May 2026
  
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  DOI: 10.1084/jem.20231882
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12121627/
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Tissue-specific tolerance mechanisms and lymph node co-drainage shape T cell immunity in the upper digestive system and pancreatic cancer progression

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Apr 2026
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An SPP1-SOCS1 pathway constrains interferon responses in tumor-associated macrophages and shapes an immunosuppressive tumor microenvironment

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1. scibot 29 Apr 2026
  
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Krüppel-like factor 2 programs early exhausted T cell states and restrains antiviral immunity

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Upregulation of TNFR2 Precedes TOX Expression by Exhausted T cells and Restricts Antitumor and Antiviral Immunity

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1. scibot 09 Apr 2026
  
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54.241.53.176 54.241.53.176

1-s2.0-S2589004226009685-main-html.html

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54.241.53.176/e6b74a01ef71dbd89d83e62d991fbd1a5fd567c9/1-s2.0-S2589004226009685-main-html.html
Feb 2026
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Stochasticity in cancer immunotherapy stems from rare but functionally critical Spark T cells

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1. scibot 06 Feb 2026
  
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CCL3 is produced by aged neutrophils across cancers and promotes tumor growth

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Meningeal blood vessel blockage enhances anti-glioblastoma immunity

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sciencedirect.com/science/article/pii/S0092867425014941
Dec 2025
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Unconventional CD8+ T cell surveillance of cytomegalovirus via Qa-1/HLA-E–restricted epitope recognition

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1. scibot 23 Dec 2025
  
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  DOI: 10.1126/sciadv.aea8707
  
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  DOI: 10.1126/sciadv.aea8707
  
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science.org/doi/10.1126/sciadv.aea8707
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Coordinated changes in stromal and hematopoietic cells that define the perinatal to juvenile transition in the mouse thymus

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1. scibot 16 Dec 2025
  
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  DOI: 10.1016/j.celrep.2025.116677
  
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A chemical agonist and the Golgi-resident lipid PI4P activate STING by inducing transmembrane helix rearrangement

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1. scibot 09 Dec 2025
  
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  DOI: 10.1016/j.immuni.2025.11.004
  
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BFAR promotes neutrophil infiltration and immunosuppressive reprogramming through the PRP19-YBX1 axis to induce immune evasion in gastric cancer

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1. scibot 06 Dec 2025
  
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  DOI: 10.1158/2326-6066.CIR-24-1011
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12670071/
Nov 2025
54.241.53.176 54.241.53.176

2025.11.06.687030v2.full-html.html

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1. scibot 13 Nov 2025
  
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54.241.53.176/61ff3c01c4fabc7d4036cd8525cf0aefcb431dbf/2025.11.06.687030v2.full-html.html
Oct 2025
54.241.53.176 54.241.53.176

2025.10.24.684274v1.full-html.html

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54.241.53.176/560b23241d86210770f41b5bc2071167c8b2fca6/2025.10.24.684274v1.full-html.html
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Optimal CXCR5 expression during Tfh maturation involves the Bhlhe40-Pou2af1 axis

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1. scibot 23 Oct 2025
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12744931/
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Medullary stromal cells define small intestinal lymph node identity in humans and mice

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1. scibot 18 Oct 2025
  
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The transcriptional repressor BLIMP1 enforces TCF-1-dependent and -independent restriction of the memory fate of CD8+ T cells

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1. scibot 08 Oct 2025
  
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sciencedirect.com/science/article/pii/S1074761325004194
Sep 2025
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IL-25-induced memory type 2 innate lymphoid cells enforce mucosal immunity

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Aug 2025
52.53.155.43 52.53.155.43

1-s2.0-S2589004225015111-main-html.html

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52.53.155.43/a3f5a6babd102e0b4daf6c38e342245ea1cdb42a/1-s2.0-S2589004225015111-main-html.html
Jul 2025
52.53.155.43 52.53.155.43

1-s2.0-S2589004225014087-main-html.html

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Mutant p53 exploits enhancers to elevate immunosuppressive chemokine expression and impair immune checkpoint inhibitors in pancreatic cancer

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Jun 2025
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Maternal vitamin D regulates the metabolic rearrangement of offspring CD4+ T cells in response to intestinal inflammation

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  DOI: 10.1016/j.celrep.2025.115857
  
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NK cells restrain cytotoxic CD8+ T cells in the submandibular gland via PD-1/PD-L1 pathway

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1. scibot 11 Jun 2025
  
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  DOI: 10.1126/sciimmunol.adl2967
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12099074/
Apr 2025
52.53.155.43 52.53.155.43

PD-html.html

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52.53.155.43/639914d725a708fad2e0783fbcce6b5221fc6f0d/PD-html.html
Mar 2025
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Metallophilic marginal zone macrophages cross-prime CD8+ T cell-mediated protective immunity against blood-borne tumors

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1. scibot 29 Mar 2025
  
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  DOI: 10.1016/j.immuni.2025.02.027
  
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Translation dysregulation in cancer as a source for targetable antigens

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52.53.155.43 52.53.155.43

PDF-html.html

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52.53.155.43/e942259e59872c6a1fa180712f861e9e05fe5109/PDF-html.html
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IRF7 controls spontaneous autoimmune germinal center and plasma cell checkpoints

1
1. scibot 21 Mar 2025
  
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  DOI: 10.1101/2025.02.04.636277
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11838595/
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Restoration of LAT activity improves CAR T cell sensitivity and persistence in response to antigen-low acute lymphoblastic leukemia

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IL-17RA signaling provides dual tumor-suppressor function during late-stage colorectal carcinogenesis

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cell.com/immunity/fulltext/S1074-7613(25)00073-1
Feb 2025
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Adiponectin reduces immune checkpoint inhibitor-induced inflammation without blocking anti-tumor immunity

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MAIT cells protect against sterile lung injury

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  DOI: 10.1016/j.celrep.2025.115275
  
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sciencedirect.com/science/article/pii/S2211124725000464
Dec 2024
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NK cells restrain cytotoxic CD8+ T cells in the submandibular gland via PD-1–PD-L1

1
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SIKs regulate HDAC7 stabilization and cytokine recall in late-stage T cell effector differentiation

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Inhibiting intracellular CD28 in cancer cells enhances antitumor immunity and overcomes anti-PD-1 resistance via targeting PD-L1

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Mutant p53 Exploits Enhancers to Elevate Immunosuppressive Chemokine Expression and Impair Immune Checkpoint Inhibitors in Pancreatic Cancer

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Hyperactivating EZH2 to augment H3K27me3 levels in regulatory T cells enhances immune suppression by driving early effector differentiation

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The cytokine Meteorin-like inhibits anti-tumor CD8+ T cell responses by disrupting mitochondrial function

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Protocol for inducing monomicrobial sepsis in mice with uropathogenic E. coli

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Tumor necrosis factor regulates leukocyte recruitment but not bacterial persistence during Staphylococcus aureus craniotomy infection

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Alterations of ceramide synthesis induce PD-L1 internalization and signaling to regulate tumor metastasis and immunotherapy response

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Proteobacteria impair anti-tumor immunity in the omentum by consuming arginine

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Pan-cancer mapping of single CD8+ T cell profiles reveals a TCF1:CXCR6 axis regulating CD28 co-stimulation and anti-tumor immunity

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Cbl-b mitigates the responsiveness of naive CD8+ T cells that experience extensive tonic T cell receptor signaling

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Mar 2024
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Protocol for the isolation of tumor cell-derived extracellular vesicles followed by in vivo metastasis assessment in a murine ovarian cancer model

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Fate mapping of Spp1 expression reveals age-dependent plasticity of disease-associated microglia-like cells after brain injury

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SMARCAL1 is a dual regulator of innate immune signaling and PD-L1 expression that promotes tumor immune evasion

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An essential role for miR-15/16 in Treg suppression and restriction of proliferation

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Interferon-g-dependent interactions between tissue-intrinsic γδ T cells and tissue-infiltrating CD8 T cells limit acute contact dermatitis

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A CSF-1R-blocking antibody/IL-10 fusion protein increases anti-tumor immunity by effectuating tumor-resident CD8+ T cells

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Quantitative control of Ets1 dosage by a multi-enhancer hub promotes Th1 cell differentiation and protects from allergic inflammation

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IL-10 production by granulocytes promotes Staphylococcus aureus craniotomy infection

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cDC1 coordinate innate and adaptive responses in the omentum required for T cell priming and memory

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Safety and efficacy of intraventricular immunovirotherapy with oncolytic HSV-1 for CNS cancers

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The aryl hydrocarbon receptor cell intrinsically promotes resident memory CD8+ T cell differentiation and function

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Splicing factor deficits render hematopoietic stem and progenitor cells sensitive to STAT3 inhibition

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ccr-22-1382-html.html

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Oct 2022
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Expansion of T memory stem cells with superior anti-tumor immunity by Urolithin A-induced mitophagy

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Lymphatic migration of unconventional T cells promotes site-specific immunity in distinct lymph nodes

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Intestinal inflammation alters the antigen-specific immune response to a skin commensal

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Mitochondrial damage-associated molecular patterns trigger arginase-dependent lymphocyte immunoregulation

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Newly recruited intraepithelial Ly6A+CCR9+CD4+ T cells protect against enteric viral infection

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Isolation and analyses of lamina propria lymphocytes from mouse intestines

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MEK inhibition overcomes chemoimmunotherapy resistance by inducing CXCL10 in cancer cells

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Maternal gut bacteria drive intestinal inflammation in offspring with neurodevelopmental disorders by altering the chromatin landscape of CD4+ T cells

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Vectored antibody gene delivery restores host B and T cell control of persistent viral infection

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Synergistic effect of non-neutralizing antibodies and interferon-γ for cross-protection against influenza

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Natural Genetic Variation Reveals Key Features of Epigenetic and Transcriptional Memory in Virus-Specific CD8 T Cells

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Gut microbiota-derived short-chain fatty acids regulate IL-17 production by mouse and human intestinal γδ T cells

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The glutathione peroxidase Gpx4 prevents lipid peroxidation and ferroptosis to sustain Treg cell activation and suppression of antitumor immunity

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Secreted gelsolin inhibits DNGR-1-dependent cross-presentation and cancer immunity

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T cell self-reactivity during thymic development dictates the timing of positive selection

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Competition for Active TGFβ Cytokine Allows for Selective Retention of Antigen-Specific Tissue- Resident Memory T Cells in the Epidermal Niche

1
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T Cell Receptor Is Required for Differentiation, but Not Maintenance, of Intestinal CD4+ Intraepithelial Lymphocytes

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Functional Genomics In Vivo Reveal Metabolic Dependencies of Pancreatic Cancer Cells

1
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Nonpeptidergic neurons suppress mast cells via glutamate to maintain skin homeostasis

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  DOI: 10.1016/j.cell.2021.03.002
  
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A unified atlas of CD8 T cell dysfunctional states in cancer and infection

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  DOI: 10.1016/j.molcel.2021.03.045
  
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Single-cell chromatin accessibility landscape identifies tissue repair program in human regulatory T cells

1
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sciencedirect.com/science/article/pii/S1074761321001199
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The persistence of interleukin-6 is regulated by a blood buffer system derived from dendritic cells

1
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Transcriptional Diversity and Niche-Specific Distribution of Leukocyte Populations during Staphylococcus aureus Craniotomy-Associated Biofilm Infection

1
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jimmunol.org/content/206/4/751
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Hepcidin-Mediated Hypoferremia Disrupts Immune Responses to Vaccination and Infection

1
1. scibot 28 Nov 2020
  
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Microbiota-Derived Metabolites Suppress Arthritis by Amplifying Aryl-Hydrocarbon Receptor Activation in Regulatory B Cells

1
1. scibot 16 Sep 2020
  
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Visualization of T Cell Migration in the Spleen Reveals a Network of Perivascular Pathways that Guide Entry into T Zones

1
1. scibot 05 Sep 2020
  
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Checkpoint Receptor TIGIT Expressed on Tim-1+ B Cells Regulates Tissue Inflammation

1
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  DOI: 10.1016/j.celrep.2020.107892
  
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sciencedirect.com/science/article/pii/S2211124720308731
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Robust Iterative Stimulation with Self-Antigens Overcomes CD8+ T Cell Tolerance to Self- and Tumor Antigens

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2562609
  
  DOI: 10.1016/j.celrep.2019.08.038
  
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Aryl Hydrocarbon Receptor Contributes to the Transcriptional Program of IL-10-Producing Regulatory B Cells

1
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  DOI: 10.1016/j.celrep.2019.10.018
  
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Cancer-Cell-Intrinsic cGAS Expression Mediates Tumor Immunogenicity

1
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Toxin-Triggered Interleukin-1 Receptor Signaling Enables Early-Life Discrimination of Pathogenic versus Commensal Skin Bacteria

1
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Qa-1-Restricted CD8+ T Cells Can Compensate for the Absence of Conventional T Cells during Viral Infection

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cell.com/cell-reports/fulltext/S2211-1247(19)30389-4
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

HIF-1α Is a Metabolic Switch between Glycolytic-Driven Migration and Oxidative Phosphorylation-Driven Immunosuppression of Tregs in Glioblastoma

1
1. scibot 13 Jan 2020
  
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Keratinocyte-Mediated Activation of the Cytokine TGF-β Maintains Skin Recirculating Memory CD8+ T Cells

1
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Untitled document

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ncbi.nlm.nih.gov/pmc/articles/PMC6461402/
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Monocyte-Derived CD11c+ Cells Acquire Plasmodium from Hepatocytes to Prime CD8 T Cell Immunity to Liver-Stage Malaria

1
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  DOI: 10.1016/j.chom.2019.02.014
  
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Interstitial Migration of CD8αβ T Cells in the Small Intestine Is Dynamic and Is Dictated by Environmental Cues

1
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  DOI: 10.1016/j.celrep.2019.02.034
  
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sciencedirect.com/science/article/pii/S2211124719302050
Nov 2017
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Commensal Microbes and Hair Follicle Morphogenesis Coordinately Drive Treg Migration into Neonatal Skin

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1. scibot 08 Nov 2017
  
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