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  1. Last 7 days
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    Deep profiling deconstructs features associated with memory CD8+ T cell tissue residence
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    1. scibot 21 Dec 2024
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  3. Dec 2024
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    Lurbinectedin sensitizes PD-L1 blockade therapy by activating STING-IFN signaling in small-cell lung cancer
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    sciencedirect.com/science/article/pii/S2666379124006232
  5. Sep 2024
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mutant p53 Exploits Enhancers to Elevate Immunosuppressive Chemokine Expression and Impair Immune Checkpoint Inhibitors in Pancreatic Cancer
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    1. scibot 27 Sep 2024
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      DOI: 10.1101/2024.08.28.609802

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    ncbi.nlm.nih.gov/pmc/articles/PMC11383995/
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    The transcription regulator ID3 maintains tumor-specific memory CD8+ T cells in draining lymph nodes during tumorigenesis
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  8. Aug 2024
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    The acetyltransferase KAT7 is required for thymic epithelial cell expansion, expression of AIRE target genes, and thymic tolerance
    1
    1. scibot 02 Aug 2024
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      DOI: 10.1126/sciimmunol.abb6032

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  10. Jul 2024
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    A synbiotic of Anaerostipes caccae and lactulose prevents and treats food allergy in mice
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    sciencedirect.com/science/article/pii/S1931312824001914
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pan-cancer mapping of single CD8+ T cell profiles reveals a TCF1:CXCR6 axis regulating CD28 co-stimulation and anti-tumor immunity
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    ncbi.nlm.nih.gov/pmc/articles/PMC11293343/
  13. May 2024
  14. www.biorxiv.org www.biorxiv.org
    The latent stage of Toxoplasma gondii is targeted by the immune response and host protective
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      DOI: 10.1101/2024.03.05.583527

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    biorxiv.org/content/10.1101/2024.03.05.583527v1
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    Immunotherapy-activated T cells recruit and skewlate-stage activated M1-like macrophagesthat are critical for therapeutic efficacy
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      DOI: 10.1016/j.ccell.2024.04.011

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    sciencedirect.com/science/article/pii/S1535610824001351
  16. Apr 2024
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    QDPR deficiency drives immune suppression in pancreatic cancer
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    sciencedirect.com/science/article/pii/S1550413124001190
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    IFNα-induced BST2+ tumor-associated macrophages facilitate immunosuppression and tumor growth in pancreatic cancer by ERK-CXCL7 signaling
    1
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    sciencedirect.com/science/article/pii/S2211124724004169
  19. Mar 2024
  20. www.sciencedirect.com www.sciencedirect.com
    Tonic TCR and IL-1β signaling mediate phenotypic alterations of naive CD4+ T cells
    2
    1. scibot 19 Mar 2024
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      DOI: 10.1016/j.celrep.2024.113954

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    sciencedirect.com/science/article/pii/S2211124724002821
  21. Feb 2024
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Revealing splenectomy-driven microRNA hsa-7b-5p’s role in pancreatic cancer progression
    1
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      RRID:AB_11125371R

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  23. Dec 2023
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    Glycosylation-modified antigens as a tolerance-inducing vaccine platform prevent anaphylaxis in a pre-clinical model of food allergy
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    1. scibot 22 Dec 2023
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    sciencedirect.com/science/article/pii/S2666379123005633
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    Synthetically mannosylated antigens induce antigen-specific humoral tolerance and reduce anti-drug antibody responses to immunogenic biologics
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  26. Nov 2023
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Five Inhibitory Receptors Display Distinct Vesicular Distributions in Murine T Cells
    1
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      DOI: 10.3390/cells12212558

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    ncbi.nlm.nih.gov/pmc/articles/PMC10649679/
  28. Oct 2023
  29. www.sciencedirect.com www.sciencedirect.com
    Kruppel-like factor 2+ CD4 T cells avert microbiota-induced intestinal inflammation
    1
    1. scibot 28 Oct 2023
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      DOI: 10.1016/j.celrep.2023.113323

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    sciencedirect.com/science/article/pii/S2211124723013359
  30. Aug 2023
  31. 52.53.155.43 52.53.155.43
    CD39 inhibition and VISTA blockade may overcome radiotherapy resistance by targeting exhausted CD8+ T cells and immunosuppressive myeloid cells
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      DOI: 10.1016/j.xcrm.2023.101151

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    CTLA-4 blockade induces CD4+ T cell IFNγ-driven microglial phagocytosis and anti-tumor function in glioblastoma
    1
    1. scibot 12 Aug 2023
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      DOI: 10.1016/j.immuni.2023.07.015

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    sciencedirect.com/science/article/abs/pii/S107476132300328X
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Five inhibitory receptors display distinct vesicular distributions in T cells
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      DOI: 10.1101/2023.07.21.550019

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    ncbi.nlm.nih.gov/pmc/articles/PMC10370166/
  34. Jul 2023
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    A distinct stimulatory cDC1 subpopulation amplifies CD8+ T cell responses in tumors for protective anti-cancer immunity
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      DOI: 10.1016/j.ccell.2023.06.008

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    sciencedirect.com/science/article/pii/S1535610823002180
  36. Jun 2023
  37. www.sciencedirect.com www.sciencedirect.com
    Tumor-derived prostaglandin E2 programs cDC1 dysfunction to impair intratumoral orchestration of anti-cancer T cell responses
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    sciencedirect.com/science/article/pii/S1074761323002285
  38. Mar 2023
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Original research: Invasive margin tissue-resident macrophages of high CD163 expression impede responses to T cell-based immunotherapy
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      DOI: 10.1136/jitc-2022-006433

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    ncbi.nlm.nih.gov/pmc/articles/PMC10016286/
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    Galectin-3 expression in donor T cells reduces GvHD severity and lethality after allogeneic hematopoietic cell transplantation
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      DOI: 10.1016/j.celrep.2023.112250

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    sciencedirect.com/science/article/pii/S2211124723002619
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    Adhesion analysis via a tumor vasculature-like microfluidic device identifies CD8+ T cells with enhanced tumor homing to improve cell therapy
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      DOI: 10.1016/j.celrep.2023.112175

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    sciencedirect.com/science/article/pii/S2211124723001869
  42. Jan 2023
  43. www.sciencedirect.com www.sciencedirect.com
    JAML immunotherapy targets recently activated tumor-infiltrating CD8+ T cells
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      DOI: 10.1016/j.celrep.2023.112040

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    sciencedirect.com/science/article/pii/S2211124723000517
  44. Nov 2022
  45. www.sciencedirect.com www.sciencedirect.com
    Chronic type I interferon signaling promotes lipid-peroxidation-driven terminal CD8+ T cell exhaustion and curtails anti-PD-1 efficacy
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    1. scibot 16 Nov 2022
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      DOI: 10.1016/j.celrep.2022.111647

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    sciencedirect.com/science/article/pii/S2211124722015182
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Delineating the transcriptional landscape and clonal diversity of virus-specific CD4+ T cells during chronic viral infection
    1
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      DOI: 10.7554/eLife.80079

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    ncbi.nlm.nih.gov/pmc/articles/PMC9629829/
  47. Jul 2022
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Increased Expression of Multiple Co-Inhibitory Molecules on Malaria-Induced CD8+ T Cells Are Associated With Increased Function Instead of Exhaustion
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    1. scibot 27 Jul 2022
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      DOI: 10.3389/fimmu.2022.878320

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    ncbi.nlm.nih.gov/pmc/articles/PMC9301332/
  49. May 2022
  50. www.sciencedirect.com www.sciencedirect.com
    WEE1 inhibition enhances the antitumor immune response to PD-L1 blockade by the concomitant activation of STING and STAT1 pathways in SCLC
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      DOI: 10.1016/j.celrep.2022.110814

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    sciencedirect.com/science/article/pii/S221112472200585X
  51. Apr 2022
  52. www.sciencedirect.com www.sciencedirect.com
    Interferons limit autoantigen-specific CD8+ T-cell expansion in the non-obese diabetic mouse
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    sciencedirect.com/science/article/pii/S2211124722005113
  53. www.sciencedirect.com www.sciencedirect.com
    Type 1 conventional dendritic cells maintain and guide the differentiation of precursors of exhausted T cells in distinct cellular niches
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      DOI: 10.1016/j.immuni.2022.03.006

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    sciencedirect.com/science/article/pii/S1074761322001297
  54. Mar 2022
  55. www.sciencedirect.com www.sciencedirect.com
    Highly mutated antibodies capable of neutralizing N276 glycan-deficient HIV after a single immunization with an Env trimer
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      DOI: 10.1016/j.celrep.2022.110485

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    sciencedirect.com/science/article/pii/S2211124722002182
  56. Sep 2021
  57. www.sciencedirect.com www.sciencedirect.com
    CD4 T cell help prevents CD8 T cell exhaustion and promotes control of Mycobacterium tuberculosis infection
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      DOI: 10.1016/j.celrep.2021.109696

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    sciencedirect.com/science/article/pii/S2211124721011438
  58. Aug 2021
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Immune mechanisms orchestrate tertiary lymphoid structures in tumors via cancer-associated fibroblasts
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      DOI: 10.1016/j.celrep.2021.109422

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    ncbi.nlm.nih.gov/pmc/articles/PMC8362934/
  60. Jun 2021
  61. www.sciencedirect.com www.sciencedirect.com
    Uptake of oxidized lipids by the scavenger receptor CD36 promotes lipid peroxidation and dysfunction in CD8+ T cells in tumors
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    1. scibot 08 Jun 2021
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      DOI: 10.1016/j.immuni.2021.05.003

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    sciencedirect.com/science/article/pii/S1074761321002090
  62. Apr 2021
  63. www.sciencedirect.com www.sciencedirect.com
    Structural basis for IL-12 and IL-23 receptor sharing reveals a gateway for shaping actions on T versus NK cells
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      DOI: 10.1016/j.cell.2021.01.018

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    sciencedirect.com/science/article/pii/S0092867421000611
  64. Mar 2021
  65. www.sciencedirect.com www.sciencedirect.com
    Comprehensive Profiling of an Aging Immune System Reveals Clonal GZMK+ CD8+ T Cells as Conserved Hallmark of Inflammaging
    1
    1. scibot 08 Mar 2021
      RRID:AB_2562616

      DOI: 10.1016/j.immuni.2020.11.005

      Resource: (BioLegend Cat# 135220, RRID:AB_2562616)

      Curator: @scibot

      SciCrunch record: RRID:AB_2562616

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      RRID:AB_2562616
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    sciencedirect.com/science/article/pii/S1074761320304921
  66. Feb 2021
  67. www.cell.com www.cell.com
    Immunogenic Chemotherapy Enhances Recruitment of CAR-T Cells to Lung Tumors and Improves Antitumor Efficacy when Combined with Checkpoint Blockade
    1
    1. scibot 24 Feb 2021
      RRID:AB_2562616

      DOI: 10.1016/j.ccell.2020.11.005

      Resource: (BioLegend Cat# 135220, RRID:AB_2562616)

      Curator: @Naa003

      SciCrunch record: RRID:AB_2562616

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      RRID:AB_2562616 RRIDCUR:Validated
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    cell.com/cancer-cell/abstract/S1535-6108(20)30597-3
  68. Sep 2020
  69. www.sciencedirect.com www.sciencedirect.com
    CD8+ T Cell Functional Exhaustion Overrides Pregnancy-Induced Fetal Antigen Alloimmunization
    1
    1. scibot 17 Sep 2020
      RRID:AB_2562616

      DOI: 10.1016/j.celrep.2020.107784

      Resource: (BioLegend Cat# 135220, RRID:AB_2562616)

      Curator: @ethanbadger

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    sciencedirect.com/science/article/pii/S2211124720307646
  70. www.sciencedirect.com www.sciencedirect.com
    Glutathione Restricts Serine Metabolism to Preserve Regulatory T Cell Function
    1
    1. scibot 13 Sep 2020
      RRID:AB_2562616

      DOI: 10.1016/j.cmet.2020.03.004

      Resource: (BioLegend Cat# 135220, RRID:AB_2562616)

      Curator: @ethanbadger

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      RRIDCUR:Validated RRID:AB_2562616
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    sciencedirect.com/science/article/pii/S1550413120301194
  71. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Multifaceted Effects of Antigen Valency on B Cell Response Composition and Differentiation In Vivo
    1
    1. scibot 12 Sep 2020
      RRID:AB_2562616

      DOI: 10.1016/j.immuni.2020.08.001

      Resource: (BioLegend Cat# 135220, RRID:AB_2562616)

      Curator: @Naa003

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      RRID:AB_2562616 RRIDCUR:Validated
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    pubmed.ncbi.nlm.nih.gov/32857950/
  72. Nov 2018
  73. www.sciencedirect.com www.sciencedirect.com
    The Transcription Factor Runx3 Establishes Chromatin Accessibility of cis-Regulatory Landscapes that Drive Memory Cytotoxic T Lymphocyte Formation
    1
    1. scibot 05 Nov 2018
      RRID:AB_2562616

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      RRID:AB_2562616
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    sciencedirect.com/science/article/pii/S1074761318301262
  74. www.sciencedirect.com www.sciencedirect.com
    T Cells Primed by Live Mycobacteria Versus a Tuberculosis Subunit Vaccine Exhibit Distinct Functional Properties
    1
    1. scibot 05 Nov 2018
      RRID:AB_2562616

      Curator: @evieth

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      (BioLegend Cat# 135220, RRID:AB_2562616)

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      RRID:AB_2562616 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S2352396417304851
  75. Nov 2017
  76. www.sciencedirect.com www.sciencedirect.com
    Enhancing CD8+ T Cell Fatty Acid Catabolism within a Metabolically Challenging Tumor Microenvironment Increases the Efficacy of Melanoma Immunotherapy
    1
    1. scibot 08 Nov 2017
      RRID:AB_2562616

      Curator: @Jmenke

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      (BioLegend Cat# 135220, RRID:AB_2562616)

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      RRID:AB_2562616 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1535610817303471