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Environmentally induced cell stiffening shapes metastatic site selection by tuning the immune vulnerability of cancer cells

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1. scibot 31 Jul 2026
  
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  DOI: 10.1016/j.immuni.2026.06.025
  
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sciencedirect.com/science/article/pii/S1074761326002761
Jul 2026
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Extracellular ATP-P2RY2 signaling drives intratumoral prostaglandin E2 accumulation and adaptive resistance to immunotherapy in solid tumors

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1. scibot 06 Jul 2026
  
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  DOI: 10.1016/j.immuni.2026.06.006
  
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  DOI: 10.1016/j.immuni.2026.06.006
  
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sciencedirect.com/science/article/pii/S1074761326002578
Apr 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

MIF Tautomerase Inhibition Protects Neurons From Immune-Mediated Cell Death

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1. scibot 25 Apr 2026
  
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  DOI: 10.1212/NXI.0000000000200568
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13105196/
Mar 2026
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A convergent uPAR-positive tumor ecosystem creates broad vulnerability to CAR T cell therapy

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1. scibot 31 Mar 2026
  
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  DOI: 10.1016/j.cell.2026.03.002
  
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sciencedirect.com/science/article/pii/S0092867426002692
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IL-4 treatment induces apoptosis of blood monocytes and proliferation of recruited injury-associated macrophages to resolve liver injury

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1. scibot 24 Mar 2026
  
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  DOI: 10.1016/j.celrep.2026.117136
  
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sciencedirect.com/science/article/pii/S2211124726002147
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Dnmt3a-dependent de novo DNA methylation enforces lineage commitment and preserves functionality of memory Th1 and Tfh cells

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1. scibot 17 Mar 2026
  
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  DOI: 10.1016/j.celrep.2026.117062
  
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sciencedirect.com/science/article/pii/S2211124726001403
Feb 2026
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Hepatocyte PLAGL2 deficiency alleviates MASH through MYD88-licensed inactivation of inflammasome

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1. scibot 20 Feb 2026
  
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  DOI: 10.1016/j.celrep.2026.116942
  
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sciencedirect.com/science/article/pii/S2211124726000203
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CCL3 is produced by aged neutrophils across cancers and promotes tumor growth

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1. scibot 06 Feb 2026
  
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  DOI: 10.1016/j.ccell.2026.01.006
  
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sciencedirect.com/science/article/pii/S1535610826000450
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Male-biased Yap1-Cd276/B7-H3 axis for immune evasion in medulloblastoma

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  DOI: 10.1016/j.ccell.2026.01.005
  
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sciencedirect.com/science/article/pii/S1535610826000449
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Stepwise epigenetic signal integration drives adaptive programming of cytotoxic lymphocytes

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1. scibot 03 Feb 2026
  
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  DOI: 10.1016/j.immuni.2026.01.004
  
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sciencedirect.com/science/article/pii/S107476132600004X
Dec 2025
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Clonal persistence dominates homeostatic intestinal IgA responses

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1. scibot 04 Dec 2025
  
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  DOI: 10.1016/j.immuni.2025.11.005
  
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sciencedirect.com:5037/science/article/pii/S1074761325005072
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Cryptococcus exploits delayed microglial activation, and microglial osteopontin/Spp1 impairs peripheral host control

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1. scibot 04 Dec 2025
  
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  DOI: 10.1016/j.chom.2025.11.008
  
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sciencedirect.com:5037/science/article/pii/S1931312825004688
Nov 2025
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GM-CSF and specific type 2 cytokines induce CD103+ and CD301b+ cell states in cDC1s and cDC2s

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1. scibot 29 Nov 2025
  
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  DOI: 10.1016/j.celrep.2025.116589
  
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sciencedirect.com:5037/science/article/pii/S2211124725013610
Oct 2025
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Absence of BCAP in myeloid cells abrogates M2 macrophage differentiation and promotes anti-tumor immunity

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1. scibot 28 Oct 2025
  
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  DOI: 10.1016/j.isci.2025.113723
  
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sciencedirect.com/science/article/pii/S2589004225019844
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Molnupiravir inhibits Bourbon virus infection and disease-associated pathology in mice

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1. scibot 25 Oct 2025
  
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  DOI: 10.1128/jvi.00740-25
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12548437/
Sep 2025
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1-s2.0-S2772572325001967-main-html.html

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1. scibot 19 Sep 2025
  
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  DOI: 10.1016/j.gastha.2025.100809
  
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52.53.155.43/0130feb0d6482fc1e66e3faa846240ab37c29c9f/1-s2.0-S2772572325001967-main-html.html
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Cancer cell and microenvironmental rewiring by ADAR1 loss impairs glioblastoma tumor growth and extends survival

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1. scibot 03 Sep 2025
  
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  DOI: 10.1016/j.celrep.2025.116151
  
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sciencedirect.com/science/article/pii/S2211124725009222
Aug 2025
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A RAS(ON) Multi-Selective Inhibitor Combination Therapy Triggers Long-term Tumor Control through Senescence-Associated Tumor-Immune Equilibrium in Pancreatic Ductal Adenocarcinoma

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1. scibot 06 Aug 2025
  
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  DOI: 10.1158/2159-8290.CD-24-1425
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12319406/
Jul 2025
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CINTER-seq: Chemical profiling reveals interaction-dependent cell landscapes and gene signatures in vivo

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1. scibot 17 Jul 2025
  
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  DOI: 10.1016/j.immuni.2025.06.011
  
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sciencedirect.com/science/article/pii/S1074761325002808
Jun 2025
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A CXCR4 partial agonist improves immunotherapy by targeting immunosuppressive neutrophils and cancer-driven granulopoiesis

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1. scibot 28 Jun 2025
  
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  DOI: 10.1016/j.ccell.2025.06.006
  
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sciencedirect.com/science/article/pii/S1535610825002569
May 2025
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Protocol for in vivo lineage tracing of regeneration-associated macrophages from injured skeletal muscle of adult mice

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1. scibot 29 May 2025
  
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  DOI: 10.1016/j.xpro.2025.103844
  
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sciencedirect.com/science/article/pii/S2666166725002503
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The gut microbiota promotes pain in fibromyalgia

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1. scibot 18 May 2025
  
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  DOI: 10.1016/j.neuron.2025.03.032
  
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sciencedirect.com/science/article/pii/S0896627325002521
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Interleukin-34-dependent perivascular macrophages promote vascular function in the brain

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1. scibot 17 May 2025
  
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  DOI: 10.1016/j.immuni.2025.04.003
  
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Regulatory T cells suppress GM-CSF-producing T helper cells via IL-2 modulation to restrain immunopathology

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  DOI: 10.1016/j.celrep.2025.115642
  
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sciencedirect.com/science/article/pii/S2211124725004139
Apr 2025
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A type 1 immune-stromal cell network mediates disease tolerance against intestinal infection

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1. scibot 24 Apr 2025
  
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  DOI: 10.1016/j.cell.2025.03.043
  
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sciencedirect.com/science/article/pii/S0092867425003952
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Bacterial pneumonia induces senescence in resident alveolar macrophages that are outcompeted by monocytes

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  DOI: 10.1016/j.celrep.2025.115571
  
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sciencedirect.com/science/article/pii/S2211124725003420
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Pre-existing intratumoral stem-like CD8+ T cells drive radiotherapy-induced tumor immunity

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1. scibot 15 Apr 2025
  
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  DOI: 10.1016/j.celrep.2025.115566
  
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sciencedirect.com/science/article/pii/S2211124725003377
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Pre-existing intratumoral stem-like CD8+ T-cells drive radiotherapy-induced tumor control

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  DOI: 10.1101/2024.10.16.618635
  
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52.53.155.43/ecad09cc9eabd42f0fef0391e2d71b5d66664c67/2024.10.16.618635.full-html.html
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Cancer-cell-derived cGAMP limits the activity of tumor-associated CD8+ T cells

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  DOI: 10.1016/j.celrep.2025.115510
  
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sciencedirect.com/science/article/pii/S2211124725002815
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Soluble CTLA-4 regulates immune homeostasis and promotes resolution of inflammation by suppressing type 1 but allowing type 2 immunity

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  DOI: 10.1016/j.immuni.2025.03.004
  
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sciencedirect.com/science/article/pii/S1074761325001232
Mar 2025
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The local microenvironment suppresses the synergy between irradiation and anti-PD1 therapy in breast-to-brain metastasis

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1. scibot 26 Mar 2025
  
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  DOI: 10.1016/j.celrep.2025.115427
  
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cell.com/cell-reports/abstract/S2211-1247(25)00198-6
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Splenic TNF-α signaling potentiates the innate-to-adaptive transition of antiviral NK cells

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1. scibot 04 Mar 2025
  
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  DOI: 10.1016/j.immuni.2025.02.012
  
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sciencedirect.com/science/article/pii/S1074761325000792
Feb 2025
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Adiponectin reduces immune checkpoint inhibitor-induced inflammation without blocking anti-tumor immunity

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1. scibot 11 Feb 2025
  
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  DOI: 10.1016/j.ccell.2025.01.004
  
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sciencedirect.com/science/article/pii/S1535610825000224
Jan 2025
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The bacterial microbiome modulates the initiation of brain metastasis by impacting the gut-to-brain axis

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1. scibot 23 Jan 2025
  
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  DOI: 10.1016/j.isci.2025.111874
  
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52.53.155.43/7d89da942243a2eaf4b37b3c4318db932749cf0d/1-s2.0-S2589004225001348-main-html.html
Dec 2024
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Deep profiling deconstructs features associated with memory CD8+ T cell tissue residence

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Gingival spatial analysis reveals geographic immunological variation in a microbiota-dependent and -independent manner

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A pan-family screen of nuclear receptors in immunocytes reveals ligand-dependent inflammasome control

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The immune landscape of murine skeletal muscle regeneration and aging

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Piezo1 channels restrain ILC2s and regulate the development of airway hyperreactivity

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Coagulation factor X promotes resistance to androgen-deprivation therapy in prostate cancer

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Distinct tumor architectures and microenvironments for the initiation of breast cancer metastasis in the brain

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Transcriptional programming mediated by the histone demethylase KDM5C regulates dendritic cell population heterogeneity and function

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Investigation of a fluorescent reporter microenvironment niche labeling strategy in experimental brain metastasis

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Fasting reshapes tissue-specific niches to improve NK cell-mediated anti-tumor immunity

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CXCL9/10-engineered dendritic cells promote T cell activation and enhance immune checkpoint blockade for lung cancer

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Protocol for transcutaneous tumor photolabeling to track immune cells in vivo using Kaede mice

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KDM6A Regulates Immune Response Genes in Multiple Myeloma

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Early cellular mechanisms of type I interferon-driven susceptibility to tuberculosis

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Uptake of tumor-derived microparticles induces metabolic reprogramming of macrophages in the early metastatic lung

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The local microenvironment drives activation of neutrophils in human brain tumors

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Macrophage-mediated extracellular matrix remodeling controls host Staphylococcus aureus susceptibility in the skin

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Single cell RNA sequencing unravels mechanisms underlying senescence-like phenotypes of Alveolar Macrophages

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Osteoprogenitor-GMP crosstalk underpins solid tumor-induced systemic immunosuppression and persists after tumor removal

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Macrophage-Targeted Therapy Unlocks Antitumoral Cross-talk between IFNγ-Secreting Lymphocytes and IL12-Producing Dendritic Cells

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Renal control of life-threatening malarial anemia

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Protocol to assess the antitumor efficacy of an immunotherapeutic peptide in syngeneic orthotopic glioma mouse models

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Microbiota-dependent and -independent postnatal development of salivary immunity

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Spatiotemporal co-dependency between macrophages and exhausted CD8+ T cells in cancer

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Interferon-γ promotes monocyte-mediated lung injury during influenza infection

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Single-cell analysis of human glioma and immune cells identifies S100A4 as an immunotherapy target

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An adjuvant strategy enabled by modulation of the physical properties of microbial ligands expands antigen immunogenicity

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Trained immunity induction by the inactivated mucosal vaccine MV130 protects against experimental viral respiratory infections

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Flow cytometry analysis of the subpopulations of mouse keratinocytes and skin immune cells

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Neoantigen-driven B cell and CD4 T follicular helper cell collaboration promotes anti-tumor CD8 T cell responses

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Cold exposure protects from neuroinflammation through immunologic reprogramming

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Disruption of the endopeptidase ADAM10-Notch signaling axis leads to skin dysbiosis and innate lymphoid cell-mediated hair follicle destruction

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Commensal Clostridiales strains mediate effective anti-cancer immune response against solid tumors

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Persistence of Systemic Murine Norovirus Is Maintained by Inflammatory Recruitment of Susceptible Myeloid Cells

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Untitled document

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May 2021
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Caspase-8-Dependent Inflammatory Responses Are Controlled by Its Adaptor, FADD, and Necroptosis

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Uncoupling of macrophage inflammation from self-renewal modulates host recovery from respiratory viral infection

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Single-Cell Mapping of Human Brain Cancer Reveals Tumor-Specific Instruction of Tissue-Invading Leukocytes

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  DOI: 10.1016/j.cell.2020.04.055
  
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Visualizing Synaptic Transfer of Tumor Antigens among Dendritic Cells

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A distal Foxp3 enhancer enables interleukin-2 dependent thymic Treg cell lineage commitment for robust immune tolerance

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Ontogenic shifts in cellular fate are linked to proteotype changes in lineage-biased hematopoietic progenitor cells

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  DOI: 10.1016/j.celrep.2021.108894
  
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CD45RB Status of CD8+ T Cell Memory Defines T Cell Receptor Affinity and Persistence

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Distinct developmental pathways from blood monocytes generate human lung macrophage diversity

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SCENITH: A Flow Cytometry-Based Method to Functionally Profile Energy Metabolism with Single-Cell Resolution

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  Anti-mouse Ly6C BV711 (Clone: HK1.4)
  
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Infiltrating Hematogenous Macrophages Aggregate Around β-Amyloid Plaques in an Age- and Sex-Dependent Manner in a Mouse Model of Alzheimer Disease

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Early Fate Defines Microglia and Non-parenchymal Brain Macrophage Development

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CD45RB Status of CD8+ T Cell Memory Defines T Cell Receptor Affinity and Persistence

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Microglial Homeostasis Requires Balanced CSF-1/CSF-2 Receptor Signaling

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Transcriptional Basis of Mouse and Human Dendritic Cell Heterogeneity

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Robust Control of a Brain-Persisting Parasite through MHC I Presentation by Infected Neurons

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  DOI: 10.1016/j.celrep.2019.05.051
  
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Untitled document

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  DOI: 10.1016/j.immuni.2019.04.006
  
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Nov 2018
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Extrathymically Generated Regulatory T Cells Establish a Niche for Intestinal Border-Dwelling Bacteria and Affect Physiologic Metabolite Balance

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High-Dimensional Single-Cell Mapping of Central Nervous System Immune Cells Reveals Distinct Myeloid Subsets in Health, Aging, and Disease

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T Cells in Nonlymphoid Tissues Give Rise to Lymph-Node-Resident Memory T Cells

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The Cytokine TGF-β Promotes the Development and Homeostasis of Alveolar Macrophages

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