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Tumor-to-dendritic cell reprogramming induces immunogenic lymphoid structures across cancers

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1. scibot 07 Nov 2026
  
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  DOI: 10.1016/j.immuni.2026.10.006
  
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sciencedirect.com/science/article/pii/S1074761326004322
Oct 2026
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Distant lymph nodes compensate for resected tumor-draining lymph nodes during cancer immunotherapy

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1. scibot 03 Oct 2026
  
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  DOI: 10.1016/j.immuni.2026.09.009
  
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sciencedirect.com/science/article/pii/S1074761326003845
Sep 2026
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Cyclin E-CDK2 regulates cancer cell transcriptional program and response to immunotherapy through BRD4

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  DOI: 10.1016/j.molcel.2026.08.007
  
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sciencedirect.com/science/article/pii/S109727652600554X
Aug 2026
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Impact of Chronic Infection-Induced Inflammation on TREG Cell Homeostasis

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1. scibot 21 Aug 2026
  
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  DOI: 10.1002/eji.70265
  
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onlinelibrary.wiley.com/doi/10.1002/eji.70265
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Subclinical cholestasis is a hallmark of gut dysbiosis causing resistance to cancer immunotherapy

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  DOI: 10.1016/j.ccell.2026.06.022
  
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sciencedirect.com/science/article/pii/S1535610826003090
Jul 2026
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LEF1 and niche factors determine T cell stemness across chronic diseases

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  DOI: 10.1016/j.cell.2026.06.022
  
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sciencedirect.com/science/article/pii/S0092867426007099
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AARS1 promotes tumor progression and immune evasion via ATF6 lactylation-mediated tryptophan metabolism in hepatocellular carcinoma

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1. scibot 03 Jul 2026
  
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  DOI: 10.1016/j.cmet.2026.06.003
  
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sciencedirect.com/science/article/pii/S1550413126002299
Jun 2026
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Oat-β-glucan potentiates anti-PD-1 efficacy through Faecalibacterium prausnitzii-derived butyrate and indole-3-propionic acid

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1. scibot 03 Jun 2026
  
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  DOI: 10.1016/j.chom.2026.05.002
  
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sciencedirect.com/science/article/pii/S1931312826001782
May 2026
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cGAS/STING sensing in dendritic cells discriminates between daptomycin sensitive and resistant Staphylococcus aureus clinical isolates

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1. scibot 22 May 2026
  
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  DOI: 10.1016/j.isci.2026.115854
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13186032/
Apr 2026
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Whole Genome Characterization of the Mechanisms of Daptomycin Resistance in Clinical and Laboratory Derived Isolates of Staphylococcus aureus

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1. scibot 24 Apr 2026
  
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  DOI: 10.1371/journal.pone.0028316
  
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54.241.53.176/67c74b90c3375f7e65bca5ea8c2ee116db2889dc/1-s2.0-S2589004226012290-main-html.html
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Upregulation of TNFR2 Precedes TOX Expression by Exhausted T cells and Restricts Antitumor and Antiviral Immunity

1
1. scibot 09 Apr 2026
  
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  DOI: 10.1158/1078-0432.CCR-24-3455
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13056295/
Feb 2026
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Candida albicans synergizes with Fusobacterium nucleatum in colorectal cancer progression via the Flo9-RadD interaction

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1. scibot 27 Feb 2026
  
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  DOI: 10.1016/j.ccell.2026.02.001
  
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sciencedirect.com/science/article/pii/S1535610826001005
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Law-NQO1 redox boosts the pentose phosphate pathway to confer stem-like properties and antitumor durability in effector CD8+ T cells

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1. scibot 26 Feb 2026
  
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  DOI: 10.1016/j.chembiol.2026.02.001
  
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sciencedirect.com/science/article/pii/S2451945626000334
Jan 2026
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Protocol for studying in vitro mouse primary thymocyte differentiation via retroviral-mediated gene expression and stromal-free stimulation

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1. scibot 13 Jan 2026
  
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  DOI: 10.1016/j.xpro.2025.104320
  
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sciencedirect.com/science/article/pii/S2666166725007269
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Microbiota utilization of intestinal amino acids modulates cancer progression and anticancer immunity

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1. scibot 06 Jan 2026
  
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  DOI: 10.1016/j.chom.2025.12.003
  
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sciencedirect.com/science/article/pii/S1931312825005220
Dec 2025
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IL-27 promotes Treg cell expression of CD122 and fitness at homeostasis

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1. scibot 23 Dec 2025
  
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  DOI: 10.1073/pnas.2519141122
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12718373/
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ARAP2 regulates responses to interferon-gamma by restricting SOCS1

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1. scibot 16 Dec 2025
  
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  DOI: 10.1016/j.celrep.2025.116667
  
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sciencedirect.com:5037/science/article/pii/S2211124725014391
Sep 2025
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ZBP1 pathway promotes tumor immunogenicity in the combination of anti-HER2 therapy and epigenetic therapy

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1. scibot 17 Sep 2025
  
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  DOI: 10.1016/j.celrep.2025.116314
  
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Elevated Transglutaminase-2 in SOX10-Deficient Melanoma Promotes Tumor Onset and Decreases Intratumoral CD4+ T Cells

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1. scibot 07 Sep 2025
  
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  DOI: 10.1158/0008-5472.CAN-24-3267
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12398951/
Aug 2025
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Tumor cell-intrinsic Decr2 regulates ferroptosis and immunotherapy efficacy

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1. scibot 05 Aug 2025
  
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  DOI: 10.1158/2326-6066.CIR-24-0519
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12314507/
Jul 2025
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Gasdermin-D-mediated epithelial-immune circuit synchronizes nutrient absorption and host defense in the small intestine

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1. scibot 25 Jul 2025
  
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  DOI: 10.1016/j.immuni.2025.06.019
  
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sciencedirect.com/science/article/pii/S1074761325003097
Jun 2025
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PDF-html.html

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  DOI: 10.1158/2326-6066.cir-24-0519
  
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52.53.155.43/b476b28c82bb83bd9fe4ec113cb042cd5e05e58b/PDF-html.html
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De-coupling immune parameters and toxicity associated with IL-12 agonism

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1. scibot 13 Jun 2025
  
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  DOI: 10.1016/j.celrep.2025.115840
  
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sciencedirect.com/science/article/pii/S2211124725006114
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Developmental epigenetic programming by Tet1/3 determines peripheral CD8 T cell fate

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1. scibot 11 Jun 2025
  
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  DOI: 10.1038/s44319-025-00439-z
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12116802/
Apr 2025
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Mitochondrial DNA released by senescent tumor cells enhances PMN-MDSC-driven immunosuppression through the cGAS-STING pathway

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1. scibot 09 Apr 2025
  
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  DOI: 10.1016/j.immuni.2025.03.005
  
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CXXC-finger protein 1 associates with FOXP3 to stabilize homeostasis and suppressive functions of regulatory T cells

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1. scibot 08 Apr 2025
  
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  DOI: 10.7554/eLife.103417
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11970909/
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Immune targeting and host-protective effects of the latent stage of Toxoplasma gondii

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  DOI: 10.1038/s41564-025-01967-z
  
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nature.com/articles/s41564-025-01967-z
Mar 2025
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Targeting tumor monocyte-intrinsic PD-L1 by rewiring STING signaling and enhancing STING agonist therapy

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1. scibot 11 Mar 2025
  
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  DOI: 10.1016/j.ccell.2025.02.014
  
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sciencedirect.com/science/article/pii/S1535610825000662
Feb 2025
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Tumor cell–intrinsic Piezo2 drives radioresistance by impairing CD8+ T cell stemness maintenance

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1. scibot 26 Feb 2025
  
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  DOI: 10.1084/jem.20231486
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11338319/
Dec 2024
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Deep profiling deconstructs features associated with memory CD8+ T cell tissue residence

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1. scibot 21 Dec 2024
  
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  DOI: 10.1016/j.immuni.2024.11.007
  
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sciencedirect.com/science/article/pii/S1074761324005223
Nov 2024
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A modified BPaL regimen for tuberculosis treatment replaces linezolid with inhaled spectinamides

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1. scibot 07 Nov 2024
  
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  DOI: 10.7554/eLife.96190
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11460978/
Sep 2024
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H3K9 lactylation in malignant cells facilitates CD8+ T cell dysfunction and poor immunotherapy response

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  DOI: 10.1016/j.celrep.2024.114686
  
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sciencedirect.com/science/article/pii/S2211124724010374
Aug 2024
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Application of a bespoke monoclonal antibody panel to characterize immune cell populations in cave nectar bats

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1. scibot 30 Aug 2024
  
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  DOI: 10.1016/j.celrep.2024.114703
  
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The acetyltransferase KAT7 is required for thymic epithelial cell expansion, expression of AIRE target genes, and thymic tolerance

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1. scibot 02 Aug 2024
  
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  DOI: 10.1126/sciimmunol.abb6032
  
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science.org/doi/10.1126/sciimmunol.abb6032
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41467_2021_22885_MOESM1_ESM (1)-html.html

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1. scibot 02 Aug 2024
  
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  DOI: 10.1038/s41467-021-22885-8
  
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52.53.155.43/d779e06fb55038a9aa2d3318096423be7b35c53c/41467_2021_22885_MOESM1_ESM (1)-html.html
Jul 2024
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Anti-tumor efficacy of HRS-4642 and its potential combination with proteasome inhibition in KRAS G12D-mutant cancer

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1. scibot 18 Jul 2024
  
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  DOI: 10.1016/j.ccell.2024.06.001
  
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cell.com/cancer-cell/abstract/S1535-6108(24)00226-5
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GRP75-dependent mitochondria-ER contacts ensure cell survival during early mouse thymocyte development

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  DOI: 10.1016/j.devcel.2024.06.007
  
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cell.com/developmental-cell/abstract/S1534-5807(24)00385-X
May 2024
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The latent stage of Toxoplasma gondii is targeted by the immune response and host protective

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1. scibot 24 May 2024
  
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  DOI: 10.1101/2024.03.05.583527
  
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biorxiv.org/content/10.1101/2024.03.05.583527v1
Feb 2024
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Unique immune profiles in Collaborative Cross mice linked to survival and viral clearance upon infection.

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ncbi.nlm.nih.gov/pmc/articles/PMC10867580/
52.53.155.43 52.53.155.43

Combined blockade of VEGF, Angiopoietin-2, and PD1 reprograms glioblastoma endothelial cells into quasi-antigen-presenting cells

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Cell-intrinsic PD-L1 ablation sustains effector CD8+ T cell responses and promotes antitumor T cell therapy

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  DOI: 10.1016/j.celrep.2024.113712
  
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sciencedirect.com/science/article/pii/S2211124724000408
Jan 2024
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Elimination of oncogenic KRAS in genetic mouse models eradicates pancreatic cancer by inducing FAS-dependent apoptosis by CD8+ T cells

2
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  DOI: 10.1016/j.devcel.2023.07.025
  
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sciencedirect.com/science/article/pii/S1534580723003945
Dec 2023
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Machine learning analysis of the T cell receptor repertoire identifies sequence features of self-reactivity

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  DOI: 10.1016/j.cels.2023.11.004
  
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sciencedirect.com/science/article/pii/S2405471223003277
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Stat5 opposes the transcription factor Tox and rewires exhausted CD8+ T cells toward durable effector-like states during chronic antigen exposure

1
1. scibot 17 Dec 2023
  
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sciencedirect.com/science/article/pii/S1074761323004879
Oct 2023
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Kruppel-like factor 2+ CD4 T cells avert microbiota-induced intestinal inflammation

1
1. scibot 28 Oct 2023
  
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  DOI: 10.1016/j.celrep.2023.113323
  
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NFAT5-dependent transcriptional stress control of endothelial cells prevents maladaptive remodeling of pulmonary arterioles in the hypoxic lung

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  DOI: 10.1101/2023.10.18.563022
  
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biorxiv.org/content/10.1101/2023.10.18.563022v1
Sep 2023
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STING signaling promotes NK cell antitumor immunity and maintains a reservoir of TCF-1+ NK cells

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1. scibot 16 Sep 2023
  
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Aug 2023
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Adrenergic nerves regulate intestinal regeneration through IL-22 signaling from type 3 innate lymphoid cells

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Elimination of oncogenic KRAS in genetic mouse models eradicates pancreatic cancer by inducing FAS-dependent apoptosis by CD8+ T cells

1
1. scibot 25 Aug 2023
  
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Characterizing CD4 T cell differentiation in mouse small intestine using T cell transfer, lamina propria preparation, and flow cytometry

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1. scibot 18 Aug 2023
  
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  DOI: 10.1016/j.xpro.2023.102485
  
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sciencedirect.com/science/article/pii/S2666166723004525
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Transplantation elicits a clonally diverse CD8+ T cell response that is comprised of potent CD43+ effectors

1
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  DOI: 10.1016/j.celrep.2023.112993
  
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sciencedirect.com/science/article/pii/S2211124723010045
Apr 2023
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Early immune pressure initiated by tissue-resident memory T cells sculpts tumor evolution in non-small cell lung cancer

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1. scibot 26 Apr 2023
  
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  DOI: 10.1016/j.ccell.2023.03.019
  
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Accumulation of branched-chain amino acids reprograms glucose metabolism in CD8+ T cells with enhanced effector function and anti-tumor response

1
1. scibot 20 Apr 2023
  
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sciencedirect.com/science/article/pii/S2211124723001973
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A preclinical randomized controlled multi-centre trial of anti-interleukin-17A treatment for acute ischaemic stroke

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  DOI: 10.1093/braincomms/fcad090
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10088471/
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cDC1 coordinate innate and adaptive responses in the omentum required for T cell priming and memory

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1. scibot 05 Apr 2023
  
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  DOI: 10.1126/sciimmunol.abq7432
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9835709/
Feb 2023
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IL-18BP mediates the balance between protective and pathological immune responses to Toxoplasma gondii

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sciencedirect.com/science/article/pii/S2211124723001584
Jan 2023
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GOT1 regulates CD8+ effector and memory T cell generation

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  DOI: 10.1016/j.celrep.2022.111987
  
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sciencedirect.com/science/article/pii/S2211124722018915
Dec 2022
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Mucosal exposure to non-tuberculous mycobacteria elicits B cell-mediated immunity against pulmonary tuberculosis

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Lipid-laden lung mesenchymal cells foster breast cancer metastasis via metabolic reprogramming of tumor cells and natural killer cells

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  DOI: 10.1016/j.cmet.2022.11.003
  
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CEACAM1 is a direct SOX10 target and inhibits melanoma immune infiltration and stemness

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  DOI: 10.1016/j.isci.2022.105524
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9682343/
Oct 2022
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IgA deficiency destabilizes immunological homeostasis towards intestinal microbiota and increases the risk of systemic immune dysregulation

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  DOI: 10.1101/2021.08.20.21261620
  
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52.53.155.43/62b31cea1ac090bac2ebe32e4dfd3474fee27f84/2021.08.20.21261620v1.full-html.html
Sep 2022
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Design, construction, and in vivo augmentation of a complex gut microbiome

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  DOI: 10.1016/j.cell.2022.08.003
  
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cell.com/cell/fulltext/S0092-8674(22)00990-4
Aug 2022
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Dysbiosis in imiquimod-induced psoriasis alters gut immunity and exacerbates colitis development

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  DOI: 10.1016/j.celrep.2022.111191
  
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Lung fibroblasts facilitate pre-metastatic niche formation by remodeling the local immune microenvironment

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Jul 2022
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Oncogenic collagen I homotrimers from cancer cells bind to α3β1 integrin and impact tumor microbiome and immunity to promote pancreatic cancer

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Mucosal chemokine adjuvant enhances synDNA vaccine-mediated responses to SARS-CoV-2 and provides heterologous protection in vivo

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  DOI: 10.1016/j.xcrm.2022.100693
  
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Jun 2022
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Androgen receptor-mediated CD8+ T cell stemness programs drive sex differences in antitumor immunity

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  DOI: 10.1016/j.immuni.2022.05.012
  
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Nt5e deficiency does not affect post-stroke inflammation and lesion size in a murine ischemia/reperfusion stroke model

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  DOI: 10.1016/j.isci.2022.104470
  
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Dec 2021
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Pre-existing chromatin accessibility and gene expression differences among naive CD4+ T cells influence effector potential

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Oct 2021
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Arthritis flares mediated by tissue-resident memory T cells in the joint

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Interleukin-10 induces interferon-γ-dependent emergency myelopoiesis

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Multilayer omics analysis reveals a non-classical retinoic acid signaling axis that regulates hematopoietic stem cell identity

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Dysregulation of ILC3s unleashes progression and immunotherapy resistance in colon cancer

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Untitled document

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Role of nuclear localization in the regulation and function of T-bet and Eomes in exhausted CD8 T cells

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Protein Prenylation Drives Discrete Signaling Programs for the Differentiation and Maintenance of Effector Treg Cells

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In vivo CD8+ T cell CRISPR screening reveals control by Fli1 in infection and cancer

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Mar 2021
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Integrin αvβ6–TGFβ–SOX4 Pathway Drives Immune Evasion in Triple-Negative Breast Cancer

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Oct 2020
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Temporal Analysis of Brd4 Displacement in the Control of B Cell Survival, Proliferation, and Differentiation

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Altered Immunity of Laboratory Mice in the Natural Environment Is Associated with Fungal Colonization

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FOXD3 Regulates VISTA Expression in Melanoma

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Developmental Relationships of Four Exhausted CD8+ T Cell Subsets Reveals Underlying Transcriptional and Epigenetic Landscape Control Mechanisms

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Interleukin-33 Induces the Enzyme Tryptophan Hydroxylase 1 to Promote Inflammatory Group 2 Innate Lymphoid Cell-Mediated Immunity

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Rewilding Nod2 and Atg16l1 Mutant Mice Uncovers Genetic and Environmental Contributions to Microbial Responses and Immune Cell Composition

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Regulatory T Cells Restrain Interleukin-2- and Blimp-1-Dependent Acquisition of Cytotoxic Function by CD4+ T Cells

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TCF-1-Centered Transcriptional Network Drives an Effector versus Exhausted CD8 T Cell-Fate Decision

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Amino Acids License Kinase mTORC1 Activity and Treg Cell Function via Small G Proteins Rag and Rheb

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Hippo Kinases Mst1 and Mst2 Sense and Amplify IL-2R−STAT5 Signaling in Regulatory T Cells to Establish Stable Regulatory Activity

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The Chemoattractant Receptor Ebi2 Drives Intranodal Naive CD4+ T Cell Peripheralization to Promote Effective Adaptive Immunity

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Lung γδ T Cells Mediate Protective Responses during Neonatal Influenza Infection that Are Associated with Type 2 Immunity

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Acid Suspends the Circadian Clock in Hypoxia through Inhibition of mTOR

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Fc Effector Function Contributes to the Activity of Human Anti-CTLA-4 Antibodies

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