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De novo pyrimidine synthesis controls germinal center B cell and plasma cell fates and systemic autoimmunity

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1. scibot 25 Jun 2026
  
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  DOI: 10.1016/j.celrep.2026.117587
  
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sciencedirect.com/science/article/pii/S2211124726006650
May 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

IRF7 controls spontaneous autoimmune germinal center and plasma cell checkpoints

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1. scibot 30 May 2026
  
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  DOI: 10.1084/jem.20231882
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12121627/
Mar 2026
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In vivo CAR-Tfh cell reprogramming restores tolerance in a mouse model of autoimmune hepatitis

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1. scibot 17 Mar 2026
  
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  DOI: 10.1016/j.stem.2026.02.006
  
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sciencedirect.com/science/article/pii/S1934590926000767
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Vascular STING activation facilitates NK cell anti-tumor immunity in small cell lung cancer

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1. scibot 06 Mar 2026
  
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  DOI: 10.1016/j.ccell.2026.02.008
  
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sciencedirect.com/science/article/pii/S1535610826001066
Jan 2026
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DF6215, an α-optimized IL-2-Fc fusion, expands immune effectors and drives robust preclinical anti-tumor activity

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1. scibot 09 Jan 2026
  
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  DOI: 10.1016/j.xcrm.2025.102518
  
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sciencedirect.com/science/article/pii/S2666379125005919
Dec 2025
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Distinct components of mRNA vaccines cooperate to instruct efficient germinal center responses

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1. scibot 17 Dec 2025
  
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  DOI: 10.1016/j.cell.2025.11.023
  
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sciencedirect.com:5037/science/article/pii/S0092867425013583
Nov 2025
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StealTHY: An immunogen-free CRISPR platform to expose concealed metastasis regulators in immunocompetent models

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1. scibot 08 Nov 2025
  
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  DOI: 10.1016/j.cell.2025.10.007
  
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sciencedirect.com/science/article/pii/S0092867425011365
Sep 2025
www.biorxiv.org www.biorxiv.org

Lactate Blocks Tertiary Lymphoid Structure Formation by Inhibiting B Cell Chemotaxis

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1. scibot 10 Sep 2025
  
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  DOI: 10.1101/2025.08.30.673054
  
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biorxiv.org/content/10.1101/2025.08.30.673054v1
Aug 2025
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Biomimetic nanoimmunotherapy boosts spatiotemporal PANoptosis and reshapes desmoplastic tumor microenvironment

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1. scibot 26 Aug 2025
  
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  DOI: 10.1016/j.xcrm.2025.102312
  
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sciencedirect.com/science/article/pii/S2666379125003854
Jul 2025
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Interferon-driven CAF reprogramming augments immunogenic response to neoadjuvant radiotherapy in colorectal cancer

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1. scibot 29 Jul 2025
  
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  DOI: 10.1016/j.xcrm.2025.102251
  
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sciencedirect.com/science/article/pii/S2666379125003246
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Cancer immunology data engine reveals secreted AOAH as a potential immunotherapy

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1. scibot 29 Jul 2025
  
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  DOI: 10.1016/j.cell.2025.07.004
  
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sciencedirect.com/science/article/pii/S0092867425007937
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High-resolution spatial mapping of cell state and lineage dynamics in vivo with PEtracer

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1. scibot 25 Jul 2025
  
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  DOI: 10.1126/science.adx3800
  
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science.org/doi/10.1126/science.adx3800
May 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Dietary targeting of TRPM8 rewires macrophage immunometabolism reducing colitis severity

1
1. scibot 19 May 2025
  
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  DOI: 10.1038/s41419-025-07553-9
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12032354/
Mar 2025
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IRF7 controls spontaneous autoimmune germinal center and plasma cell checkpoints

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1. scibot 21 Mar 2025
  
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  RRID:AB_2563067
  
  DOI: 10.1101/2025.02.04.636277
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11838595/
Feb 2025
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An oral tricyclic STING agonist suppresses tumor growth through remodeling of the immune microenvironment

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1. scibot 04 Feb 2025
  
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  DOI: 10.1016/j.chembiol.2025.01.004
  
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sciencedirect.com/science/article/pii/S2451945625000042
Dec 2024
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Inflammation switches the chemoattractant requirements for naive lymphocyte entry into lymph nodes

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1. scibot 21 Dec 2024
  
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  DOI: 10.1016/j.cell.2024.11.031
  
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sciencedirect.com/science/article/pii/S0092867424013473
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Type I IFN-mediated NET release promotes Mycobacterium tuberculosis replication and is associated with granuloma caseation

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1. scibot 05 Dec 2024
  
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  RRID:AB_2563067
  
  DOI: 10.1016/j.chom.2024.11.008
  
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sciencedirect.com/science/article/pii/S1931312824004396
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A pan-family screen of nuclear receptors in immunocytes reveals ligand-dependent inflammasome control

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1. scibot 02 Dec 2024
  
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  DOI: 10.1016/j.immuni.2024.10.010
  
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sciencedirect.com/science/article/pii/S1074761324004904
Jun 2024
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Protein-energy restriction-induced lipid metabolism disruption causes stable-to-progressive disease shift in Mycobacterium avium-infected female mice

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1. scibot 21 Jun 2024
  
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  DOI: 10.1016/j.ebiom.2024.105198
  
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sciencedirect.com/science/article/pii/S2352396424002330
May 2024
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A targeted single mutation in influenza A virus universal epitope transforms immunogenicity and protective immunity via CD4+ T cell activation

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1. scibot 31 May 2024
  
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  DOI: 10.1016/j.celrep.2024.114259
  
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sciencedirect.com/science/article/pii/S2211124724005874
Apr 2024
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Transcription factor Tox2 is required for metabolic adaptation and tissue residency of ILC3 in the gut

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1. scibot 30 Apr 2024
  
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  DOI: 10.1016/j.immuni.2024.04.001
  
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sciencedirect.com/science/article/pii/S1074761324002061
Jun 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Attenuated Mycobacterium tuberculosis vaccine protection in a low-dose murine challenge model

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1. scibot 30 Jun 2023
  
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  DOI: 10.1016/j.isci.2023.106963
  
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  DOI: 10.1016/j.isci.2023.106963
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10291467/
May 2023
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STAT3 signaling in B cells controls germinal center zone organization and recycling

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1. scibot 18 May 2023
  
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  DOI: 10.1016/j.celrep.2023.112512
  
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sciencedirect.com/science/article/pii/S2211124723005235
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The T-cell-directed vaccine BNT162b4 encoding conserved non-spike antigens protects animals from severe SARS-CoV-2 infection

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1. scibot 11 May 2023
  
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  DOI: 10.1016/j.cell.2023.04.007
  
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sciencedirect.com/science/article/pii/S0092867423004038
Jan 2023
www.frontiersin.org www.frontiersin.org

A CRISPR/Cas9-mediated screen identifies determinants of early plasma cell differentiation

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1. scibot 22 Jan 2023
  
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  DOI: 10.3389/fimmu.2022.1083119
  
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frontiersin.org/journals/immunology/articles/10.3389/fimmu.2022.1083119/full
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Flt3- and Tie2-Cre tracing identifies regeneration in sepsis from multipotent progenitors but not hematopoietic stem cells

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1. scibot 19 Jan 2023
  
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  DOI: 10.1016/j.stem.2022.12.014
  
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sciencedirect.com/science/article/pii/S1934590922004982
Dec 2022
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Splicing factor deficits render hematopoietic stem and progenitor cells sensitive to STAT3 inhibition

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1. scibot 18 Dec 2022
  
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  DOI: 10.1016/j.celrep.2022.111825
  
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sciencedirect.com/science/article/pii/S221112472201717X
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Mucosal exposure to non-tuberculous mycobacteria elicits B cell-mediated immunity against pulmonary tuberculosis

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1. scibot 18 Dec 2022
  
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  DOI: 10.1016/j.celrep.2022.111783
  
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sciencedirect.com/science/article/pii/S2211124722016710
Oct 2022
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

A neutrophil–B-cell axis impacts tissue damage control in a mouse model of intraabdominal bacterial infection via Cxcr4

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1. scibot 04 Oct 2022
  
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  DOI: 10.7554/eLife.78291
  
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pmc.ncbi.nlm.nih.gov/articles/PMC9525059/
May 2022
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Isolation and analyses of lamina propria lymphocytes from mouse intestines

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1. scibot 12 May 2022
  
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  DOI: 10.1016/j.xpro.2022.101366
  
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sciencedirect.com/science/article/pii/S2666166722002465
Jan 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

ACE2 is the critical in vivo receptor for SARS-CoV-2 in a novel COVID-19 mouse model with TNF- and IFNγ-driven immunopathology

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1. scibot 26 Jan 2022
  
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  DOI: 10.7554/eLife.74623
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8776253/
Dec 2021
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Maternal gut bacteria drive intestinal inflammation in offspring with neurodevelopmental disorders by altering the chromatin landscape of CD4+ T cells

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1. scibot 08 Dec 2021
  
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  DOI: 10.1016/j.immuni.2021.11.005
  
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sciencedirect.com/science/article/pii/S1074761321004969
Nov 2021
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ILC3s control airway inflammation by limiting T cell responses to allergens and microbes

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1. scibot 24 Nov 2021
  
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  DOI: 10.1016/j.celrep.2021.110051
  
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sciencedirect.com/science/article/pii/S2211124721015370
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Ileitis-associated tertiary lymphoid organs arise at lymphatic valves and impede mesenteric lymph flow in response to tumor necrosis factor

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1. scibot 17 Nov 2021
  
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  DOI: 10.1016/j.immuni.2021.10.003
  
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sciencedirect.com/science/article/pii/S107476132100409X
Oct 2021
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Early developing B cells undergo negative selection by central nervous system-specific antigens in the meninges

1
1. scibot 09 Oct 2021
  
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  DOI: 10.1016/j.immuni.2021.09.016
  
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sciencedirect.com/science/article/pii/S1074761321004015
Jun 2021
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Resistance to lethal ectromelia virus infection requires Type I interferon receptor in natural killer cells and monocytes but not in adaptive immune or parenchymal cells

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1. scibot 17 Jun 2021
  
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  RRID:AB_2563067
  
  DOI: 10.1371/journal.ppat.1009593
  
  Resource: (BioLegend Cat# 115540, RRID:AB_2563067)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8172060/
Feb 2021
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SARS-CoV-2 mRNA Vaccines Foster Potent Antigen-Specific Germinal Center Responses Associated with Neutralizing Antibody Generation

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1. scibot 27 Feb 2021
  
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  RRID:AB_2563067
  
  DOI: 10.1016/j.immuni.2020.11.009
  
  Resource: (BioLegend Cat# 115540, RRID:AB_2563067)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7680029/
Jan 2021
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Nod1 promotes colorectal carcinogenesis by regulating the immunosuppressive functions of tumor-infiltrating myeloid cells

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1. scibot 28 Jan 2021
  
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  RRID:AB_2563067
  
  DOI: 10.1016/j.celrep.2020.108677
  
  Resource: (BioLegend Cat# 115540, RRID:AB_2563067)
  
  Curator: @Naa003
  
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sciencedirect.com/science/article/pii/S2211124720316661
Oct 2020
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Continued Bcl6 Expression Prevents the Transdifferentiation of Established Tfh Cells into Th1 Cells during Acute Viral Infection

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1. scibot 08 Oct 2020
  
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  RRID:AB_2563067
  
  DOI: 10.1016/j.celrep.2020.108232
  
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sciencedirect.com/science/article/pii/S2211124720312213
Nov 2018
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Tumor-Derived cGAMP Triggers a STING-Mediated Interferon Response in Non-tumor Cells to Activate the NK Cell Response

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1. scibot 05 Nov 2018
  
  in Public
  
  RRID:AB_2563067
  
  Curator: @Jmenke
  
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sciencedirect.com/science/article/pii/S107476131830431X