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Engineered receptor-biased IL-2–drug immunoconjugates selectively expand Tregs and suppress effector cells for autoimmune therapy

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1. scibot 06 Nov 2026
  
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  DOI: 10.1016/j.xcrm.2026.103127
  
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sciencedirect.com/science/article/pii/S2666379126005446
Jul 2026
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Extracellular ATP-P2RY2 signaling drives intratumoral prostaglandin E2 accumulation and adaptive resistance to immunotherapy in solid tumors

2
1. scibot 06 Jul 2026
  
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  DOI: 10.1016/j.immuni.2026.06.006
  
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2. scibot 05 Jul 2026
  
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  RRID: AB_2564285
  
  DOI: 10.1016/j.immuni.2026.06.006
  
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sciencedirect.com/science/article/pii/S1074761326002578
Apr 2026
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MAIT cells egress the thymus at several maturation stages with selective capacity to seed different tissues

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1. scibot 24 Apr 2026
  
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  DOI: 10.1016/j.immuni.2026.03.024
  
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sciencedirect.com/science/article/pii/S1074761326001354
Aug 2025
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Tumor-associated Schwann cell remodeling under metabolic stress via lactate sensing orchestrates pancreatic ductal adenocarcinoma development

1
1. scibot 13 Aug 2025
  
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  DOI: 10.1016/j.cmet.2025.07.008
  
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sciencedirect.com/science/article/pii/S1550413125003353
Jul 2025
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Adoptively transferred Th17 cells cooperate with host B cells to achieve durable tumor immunity

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1. scibot 25 Jul 2025
  
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  DOI: 10.1016/j.ccell.2025.07.001
  
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sciencedirect.com/science/article/pii/S1535610825002727
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KEAP1 and STK11/LKB1 alterations enhance vulnerability to ATR inhibition in KRAS mutant non-small cell lung cancer

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1. scibot 15 Jul 2025
  
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  DOI: 10.1016/j.ccell.2025.06.011
  
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sciencedirect.com/science/article/pii/S1535610825002612
Jun 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

KMT2D coordinates antiviral CD4+ T cell responses through opposing effects on T follicular helper and cytotoxic gene expression

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1. scibot 03 Jun 2025
  
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  RRID:AB_2564285
  
  DOI: 10.1016/j.celrep.2025.115775
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12302258/
Dec 2024
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IL-17A/CEBPβ/OPN/LYVE-1 axis inhibits anti-tumor immunity by promoting tumor-associated tissue-resident macrophages

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1. scibot 12 Dec 2024
  
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  DOI: 10.1016/j.celrep.2024.115039
  
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sciencedirect.com/science/article/pii/S2211124724013901
Oct 2024
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Damping excessive viral-induced IFN-γ rescues the impaired anti-Aspergillus host immune response in influenza-associated pulmonary aspergillosis

1
1. scibot 02 Oct 2024
  
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  AB_2564285
  
  DOI: 10.1016/j.ebiom.2024.105347
  
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sciencedirect.com/science/article/pii/S2352396424003839
Sep 2024
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A PD-1-targeted, receptor-masked IL-2 immunocytokine that engages IL-2Rα strengthens T cell-mediated anti-tumor therapies

1
1. scibot 27 Sep 2024
  
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  AB_2564285
  
  DOI: 10.1016/j.xcrm.2024.101747
  
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sciencedirect.com/science/article/pii/S2666379124004774
May 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Patients and mice with deficiency in the SNARE protein SYNTAXIN-11 have a secondary B cell defect

1
1. scibot 15 May 2024
  
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  RRID:AB_2564285
  
  DOI: 10.1084/jem.20221122
  
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  Curator: @evieth
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11082451/
Oct 2023
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Upregulation of exosome secretion from tumor-associated macrophages plays a key role in the suppression of anti-tumor immunity

1
1. scibot 13 Oct 2023
  
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  DOI: 10.1016/j.celrep.2023.113224
  
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sciencedirect.com/science/article/pii/S2211124723012366
Aug 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Activating Inducible T cell Co-stimulator (ICOS) yields anti-tumor activity alone and in combination with anti-PD-1 checkpoint blockade

3
1. scibot 26 Aug 2023
  
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  RRID:AB_2564285
  
  DOI: 10.1158/2767-9764.CRC-22-0293
  
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2. scibot 26 Aug 2023
  
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  RRID:AB_2564285
  
  DOI: 10.1158/2767-9764.CRC-22-0293
  
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3. scibot 26 Aug 2023
  
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  RRID:AB_2564285
  
  DOI: 10.1158/2767-9764.CRC-22-0293
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10430783/
Jul 2023
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Tumor-specific CD4 T cells instruct monocyte fate in pancreatic ductal adenocarcinoma

1
1. scibot 06 Jul 2023
  
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  RRID:AB_2564285
  
  DOI: 10.1016/j.celrep.2023.112732
  
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sciencedirect.com/science/article/pii/S221112472300743X
Mar 2023
europepmc.org europepmc.org

mRNAs encoding IL-12 and a decoy-resistant variant of IL-18 synergize to engineer T cells for efficacious intratumoral adoptive immunotherapy

1
1. scibot 22 Mar 2023
  
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  RRID:AB_2564285
  
  DOI: 10.1016/j.xcrm.2023.100978
  
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europepmc.org/article/med/36933554
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Adhesion analysis via a tumor vasculature-like microfluidic device identifies CD8+ T cells with enhanced tumor homing to improve cell therapy

1
1. scibot 03 Mar 2023
  
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  RRID:AB_2564285
  
  DOI: 10.1016/j.celrep.2023.112175
  
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sciencedirect.com/science/article/pii/S2211124723001869
Feb 2023
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IL-18BP mediates the balance between protective and pathological immune responses to Toxoplasma gondii

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1. scibot 24 Feb 2023
  
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  DOI: 10.1016/j.celrep.2023.112147
  
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sciencedirect.com/science/article/pii/S2211124723001584
Dec 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

T follicular helper cells and the germinal centre are required for memory B cell formation and humoral immunity after ChAdOx1 nCoV-19 vaccination.

1
1. scibot 02 Dec 2022
  
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  DOI: 10.1016/j.xcrm.2022.100845
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9663747/
Nov 2022
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Chronic type I interferon signaling promotes lipid-peroxidation-driven terminal CD8+ T cell exhaustion and curtails anti-PD-1 efficacy

1
1. scibot 16 Nov 2022
  
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  DOI: 10.1016/j.celrep.2022.111647
  
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sciencedirect.com/science/article/pii/S2211124722015182
Nov 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Impaired HA-specific T follicular helper cell and antibody responses to influenza vaccination are linked to inflammation in humans

1
1. scibot 05 Nov 2021
  
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  DOI: 10.7554/eLife.70554
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8562996/
Apr 2021
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HER2-targeted antibody-drug conjugate induces host immunity against cancer stem cells

1
1. scibot 28 Apr 2021
  
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  DOI: 10.1016/j.chembiol.2021.02.013
  
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sciencedirect.com/science/article/pii/S2451945621000982
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

In vivo CD8+ T cell CRISPR screening reveals control by Fli1 in infection and cancer

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1. scibot 11 Apr 2021
  
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  DOI: 10.1016/j.cell.2021.02.019
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8054351/
Feb 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A Booster Dose Enhances Immunogenicity of the COVID-19 Vaccine Candidate ChAdOx1 nCoV-19 in Aged Mice

1
1. scibot 28 Feb 2021
  
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  RRID:AB_2564285
  
  DOI: 10.1016/j.medj.2020.12.006
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7833318/
Jan 2020
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TCF-1-Centered Transcriptional Network Drives an Effector versus Exhausted CD8 T Cell-Fate Decision

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2564285
  
  DOI: 10.1016/j.immuni.2019.09.013
  
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  Curator: @ethanbadger
  
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  RRID:AB_2564285 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1074761319304091