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Structural analysis of de novo-designed binders targeting the closed state of HSP90

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  DOI: 10.1016/j.str.2026.09.007
  
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sciencedirect.com/science/article/pii/S0969212626002935
Aug 2026
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Mitotic single-stranded DNA suppression by DDIAS

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1. scibot 27 Aug 2026
  
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  DOI: 10.1016/j.molcel.2026.07.034
  
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sciencedirect.com/science/article/pii/S1097276526005204
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Nascent chain folding status modulates ribosome dynamics and mRNA stability through the ribosome-associated chaperone Zuo1

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  DOI: 10.1016/j.molcel.2026.06.041
  
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cell.com/molecular-cell/abstract/S1097-2765(26)00457-0
Jul 2026
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Nascent chain folding status modulates ribosome dynamics and mRNA stability through the ribosome-associated chaperone Zuo1

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1. scibot 23 Jul 2026
  
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  DOI: 10.1016/j.molcel.2026.06.041
  
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cell.com/molecular-cell/abstract/S1097-2765(26)00457-0
Apr 2026
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1-s2.0-S2589004226010941-main-html.html

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  DOI: 10.1016/j.isci.2026.115719
  
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54.241.53.176/14b18a1671817b8792c9cef0cebe2ab151315349/1-s2.0-S2589004226010941-main-html.html
Mar 2026
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Differential conservation analysis identifies residues defining constitutive internalization in beta-adrenergic receptors

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1. scibot 03 Mar 2026
  
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  DOI: 10.1016/j.isci.2026.115033
  
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sciencedirect.com/science/article/pii/S2589004226004086
Dec 2025
advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com

TBK1 Induces the Formation of Optineurin Filaments That Condensate with Polyubiquitin and LC3 for Cargo Sequestration

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1. scibot 23 Dec 2025
  
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  DOI: 10.1002/advs.202509927
  
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advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202509927
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FEBS Press

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  DOI: 10.1111/febs.70365
  
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febs.onlinelibrary.wiley.com/doi/10.1111/febs.70365
Jul 2025
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RNF13 is a novel interactor of iduronate 2-sulfatase that modifies its glycosylation and maturation

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1. scibot 12 Jul 2025
  
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  DOI: 10.1101/2025.06.20.660705
  
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biorxiv.org/content/10.1101/2025.06.20.660705v1
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Dual-specific autophosphorylation of kinase IKK2 enables phosphorylation of substrate IκBα through a phosphoenzyme intermediate

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1. scibot 02 Jul 2025
  
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  DOI: 10.7554/eLife.98009
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12208667/
Jun 2025
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Microprotein SMIM26 drives oxidative metabolism via serine-responsive mitochondrial translation

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1. scibot 28 Jun 2025
  
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  DOI: 10.1016/j.molcel.2025.05.033
  
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sciencedirect.com/science/article/pii/S1097276525004721
May 2025
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RNF13 variants L311S and L312P associated with developmental epileptic encephalopathy alter dendritic organization in hippocampal neurons

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1. scibot 17 May 2025
  
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  DOI: 10.1016/j.ibneur.2025.04.004
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12018061/
Dec 2024
52.53.155.43 52.53.155.43

1-s2.0-S2589004224028001-main-html.html

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1. scibot 12 Dec 2024
  
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  DOI: 10.1016/j.isci.2024.111573
  
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52.53.155.43/2ec295bdc94e6971f9f06439deb8506e38a12f60/1-s2.0-S2589004224028001-main-html.html
Sep 2024
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The Aspartic Protease Ddi1 Contributes to DNA-Protein Crosslink Repair in Yeast

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1. scibot 25 Sep 2024
  
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  DOI: 10.1016/j.molcel.2019.12.007
  
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sciencedirect.com/science/article/pii/S1097276519308986
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The RNA-Binding Protein YBX3 Controls Amino Acid Levels by Regulating SLC mRNA Abundance

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1. scibot 25 Sep 2024
  
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  DOI: 10.1016/j.celrep.2019.05.039
  
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sciencedirect.com/science/article/pii/S221112471930659X
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S-acylation of NLRP3 provides a nigericin sensitive gating mechanism that controls access to the Golgi

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1. scibot 18 Sep 2024
  
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  DOI: 10.7554/eLife.94302
  
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elifesciences.org/articles/94302
Jul 2024
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Proteomic analysis reveals a PLK1-dependent G2/M degradation program and a role for AKAP2 in coordinating the mitotic cytoskeleton

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1. scibot 17 Jul 2024
  
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  DOI: 10.1016/j.celrep.2024.114510
  
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sciencedirect.com/science/article/pii/S2211124724008398
Mar 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Neuron type-specific proteomics reveals distinct Shank3 proteoforms in iPSNs and dSPNs lead to striatal synaptopathy in Shank3B–/– mice

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1. scibot 15 Mar 2024
  
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  DOI: 10.1038/s41380-024-02493-w
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11412912/
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The CARD8 inflammasome dictates HIV/SIV pathogenesis and disease progression

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1. scibot 01 Mar 2024
  
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  DOI: 10.1016/j.cell.2024.01.048
  
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  DOI: 10.1016/j.cell.2024.01.048
  
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sciencedirect.com/science/article/pii/S009286742400117X
Feb 2024
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SERTAD1 initiates NLRP3-mediated inflammasome activation through restricting NLRP3 polyubiquitination

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1. scibot 13 Feb 2024
  
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  DOI: 10.1016/j.celrep.2024.113752
  
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  DOI: 10.1016/j.celrep.2024.113752
  
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sciencedirect.com/science/article/pii/S2211124724000809
Dec 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

NEMO reshapes the α-Synuclein aggregate interface and acts as an autophagy adapter by co-condensation with p62

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1. scibot 22 Dec 2023
  
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  DOI: 10.1038/s41467-023-44033-0
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10730909/
Aug 2023
52.53.155.43 52.53.155.43

LINC00116-Encoded Microprotein Mitoregulin Regulates Fatty Acid Metabolism at the Mitochondrial Outer Membrane

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1. scibot 19 Aug 2023
  
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  DOI: 10.1016/j.isci.2023.107558
  
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52.53.155.43/059bf8b11a4bdbbc7113047ac5328dabaca7c676/PIIS2589004223016358-html.html
Jul 2023
52.53.155.43 52.53.155.43

NEMO reshapes the protein aggregate interface and promotes aggrephagy by co-condensation with p62

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1. scibot 19 Jul 2023
  
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  DOI: 10.1101/2023.06.05.543428
  
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52.53.155.43/5185b06857919afc7fae38712332798a8a903a3a/2023.06.05.543428v1.full-html.html
May 2023
www.biorxiv.org www.biorxiv.org

Neuron-specific protein expression at striatal excitatory synapses

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1. scibot 18 May 2023
  
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  DOI: 10.1101/2023.03.16.532957
  
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biorxiv.org/content/10.1101/2023.03.16.532957v1
Apr 2023
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Apicosome: newly identified cell-type-specific organelle in mouse cochlear and vestibular hair cells

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1. scibot 23 Apr 2023
  
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  DOI: 10.1016/j.isci.2023.106535
  
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sciencedirect.com/science/article/pii/S2589004223006120
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Lysine long-chain fatty acylation regulates the TEAD transcription factor

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  DOI: 10.1016/j.celrep.2023.112388
  
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sciencedirect.com/science/article/pii/S2211124723003996
Mar 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Comprehensive characterization of the embryonic factor LEUTX

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1. scibot 04 Mar 2023
  
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  DOI: 10.1016/j.isci.2023.106172
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9978639/
Jan 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Native holdup (nHU) to measure binding affinities from cell extracts

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1. scibot 06 Jan 2023
  
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  DOI: 10.1126/sciadv.ade3828
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9770967/
Dec 2022
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AKTIP loss is enriched in ERα-positive breast cancer for tumorigenesis and confers endocrine resistance

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  DOI: 10.1016/j.celrep.2022.111821
  
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sciencedirect.com/science/article/pii/S2211124722017132
Sep 2022
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Functional rewiring of G protein-coupled receptor signaling in human labor

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  DOI: 10.1016/j.celrep.2022.111318
  
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sciencedirect.com/science/article/pii/S2211124722011421
Aug 2022
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PABP/purine-rich motif as an initiation module for cap-independent translation in pattern-triggered immunity

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  DOI: 10.1016/j.cell.2022.06.037
  
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sciencedirect.com/science/article/pii/S0092867422007899
Jul 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Membrane Targeting and GTPase Activity of Rab7 Are Required for Its Ubiquitination by RNF167

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1. scibot 31 Jul 2022
  
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  DOI: 10.3390/ijms23147847
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9319455/
Jan 2022
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Seipin localizes at endoplasmic-reticulum-mitochondria contact sites to control mitochondrial calcium import and metabolism in adipocytes

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1. scibot 12 Jan 2022
  
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  DOI: 10.1016/j.celrep.2021.110213
  
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sciencedirect.com/science/article/pii/S2211124721017174
Nov 2021
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RNF13 Dileucine Motif Variants L311S and L312P Interfere with Endosomal Localization and AP-3 Complex Association

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Oct 2021
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Mitophagy antagonism by ZIKV reveals Ajuba as a regulator of PINK1 signaling, PKR-dependent inflammation, and viral invasion of tissues

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Argonaute-miRNA Complexes Silence Target mRNAs in the Nucleus of Mammalian Stem Cells

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TRIM7 inhibits enterovirus replication and promotes emergence of a viral variant with increased pathogenicity

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ELAVL1 primarily couples mRNA stability with the 3′ UTRs of interferon-stimulated genes

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Robo recruitment of the Wave regulatory complex plays an essential and conserved role in midline repulsion

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Formation of NPR1 Condensates Promotes Cell Survival during the Plant Immune Response

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Subcellular sorting of neuregulins controls the assembly of excitatory-inhibitory cortical circuits

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Expanded Coverage of the 26S Proteasome Conformational Landscape Reveals Mechanisms of Peptidase Gating

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Chemical genetics and proteome-wide site mapping reveal cysteine MARylation by PARP-7 on immune-relevant protein targets

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Nov 2020
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Coupled Control of Distal Axon Integrity and Somal Responses to Axonal Damage by the Palmitoyl Acyltransferase ZDHHC17

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The Deubiquitinating Enzyme Ataxin-3 Regulates Ciliogenesis and Phagocytosis in the Retina

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The Tumour Suppressor TMEM127 Is a Nedd4-Family E3 Ligase Adaptor Required by Salmonella SteD to Ubiquitinate and Degrade MHC Class II Molecules

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Discovery of Widespread Host Protein Interactions with the Pre-replicated Genome of CHIKV Using VIR-CLASP

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Cell Type–Specific Expression Analysis of the Inner Ear: A Technical Report

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Expanded Coverage of the 26S Proteasome Conformational Landscape Reveals Mechanisms of Peptidase Gating

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Jan 2020
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Non-covalent NRF2 Activation Confers Greater Cellular Protection than Covalent Activation

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Butyrophilin-like 3 Directly Binds a Human Vγ4+ T Cell Receptor Using a Modality Distinct from Clonally-Restricted Antigen

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A ZDHHC5-GOLGA7 Protein Acyltransferase Complex Promotes Nonapoptotic Cell Death

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Untitled document

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Filopodia Conduct Target Selection in Cortical Neurons Using Differences in Signal Kinetics of a Single Kinase

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jneurosci.org/content/38/1/200
Nov 2017
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Nuclear Pore Permeabilization Is a Convergent Signaling Event in Effector-Triggered Immunity

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