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RAF-independent MEK mutations drive refractory histiocytic neoplasms but respond to ERK inhibition

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1. scibot 28 Oct 2025
  
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  DOI: 10.1016/j.ccell.2025.09.014
  
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sciencedirect.com/science/article/pii/S1535610825004064
Oct 2025
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The transcriptional repressor BLIMP1 enforces TCF-1-dependent and -independent restriction of the memory fate of CD8+ T cells

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1. scibot 08 Oct 2025
  
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  DOI: 10.1016/j.immuni.2025.09.008
  
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sciencedirect.com/science/article/pii/S1074761325004194
Sep 2025
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Amyloid-β-driven Alzheimer’s disease reshapes the colonic immune system in mice

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1. scibot 03 Sep 2025
  
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  DOI: 10.1016/j.celrep.2025.116109
  
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sciencedirect.com/science/article/pii/S2211124725008800
Jun 2025
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Prolonged but finite antigen presentation promotes reversible defects of “helpless” memory CD8+ T cells

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1. scibot 26 Jun 2025
  
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  DOI: 10.1016/j.immuni.2025.05.025
  
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sciencedirect.com/science/article/pii/S1074761325002468
May 2025
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Monocytes can efficiently replace all brain macrophages and fetal liver monocytes can generate bona fide SALL1+ microglia

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1. scibot 17 May 2025
  
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  DOI: 10.1016/j.immuni.2025.04.006
  
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sciencedirect.com/science/article/pii/S1074761325001694
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Interleukin-34-dependent perivascular macrophages promote vascular function in the brain

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1. scibot 17 May 2025
  
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  DOI: 10.1016/j.immuni.2025.04.003
  
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sciencedirect.com/science/article/pii/S1074761325001669
Apr 2025
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Pre-existing intratumoral stem-like CD8+ T cells drive radiotherapy-induced tumor immunity

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1. scibot 15 Apr 2025
  
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  DOI: 10.1016/j.celrep.2025.115566
  
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sciencedirect.com/science/article/pii/S2211124725003377
52.53.155.43 52.53.155.43

Pre-existing intratumoral stem-like CD8+ T-cells drive radiotherapy-induced tumor control

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1. scibot 11 Apr 2025
  
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  DOI: 10.1101/2024.10.16.618635
  
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52.53.155.43/ecad09cc9eabd42f0fef0391e2d71b5d66664c67/2024.10.16.618635.full-html.html
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Cancer-cell-derived cGAMP limits the activity of tumor-associated CD8+ T cells

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1. scibot 03 Apr 2025
  
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  DOI: 10.1016/j.celrep.2025.115510
  
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sciencedirect.com/science/article/pii/S2211124725002815
Feb 2025
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A microRNA-regulated transcriptional state defines intratumoral CD8+ T cells that respond to immunotherapy

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1. scibot 14 Feb 2025
  
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  DOI: 10.1016/j.celrep.2025.115301
  
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sciencedirect.com/science/article/pii/S2211124725000725
Nov 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A modified BPaL regimen for tuberculosis treatment replaces linezolid with inhaled spectinamides

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1. scibot 07 Nov 2024
  
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  DOI: 10.7554/eLife.96190
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11460978/
Sep 2024
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Intercellular nanotube-mediated mitochondrial transfer enhances T cell metabolic fitness and antitumor efficacy

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1. scibot 17 Sep 2024
  
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  DOI: 10.1016/j.cell.2024.08.029
  
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sciencedirect.com/science/article/pii/S0092867424009565
Aug 2024
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LAG-3 sustains TOX expression and regulates the CD94/NKG2-Qa-1b axis to govern exhausted CD8 T cell NK receptor expression and cytotoxicity

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1. scibot 20 Aug 2024
  
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  DOI: 10.1016/j.cell.2024.07.018
  
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sciencedirect.com/science/article/pii/S0092867424007785
Jun 2024
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Fasting reshapes tissue-specific niches to improve NK cell-mediated anti-tumor immunity

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1. scibot 21 Jun 2024
  
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  DOI: 10.1016/j.immuni.2024.05.021
  
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sciencedirect.com/science/article/pii/S1074761324002759
Dec 2023
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Stat5 opposes the transcription factor Tox and rewires exhausted CD8+ T cells toward durable effector-like states during chronic antigen exposure

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1. scibot 17 Dec 2023
  
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  DOI: 10.1016/j.immuni.2023.11.005
  
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sciencedirect.com/science/article/pii/S1074761323004879
Aug 2023
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The pseudokinase Trib1 regulates the transition of exhausted T cells to a KLR+ CD8+ effector state, and its deletion improves checkpoint blockade

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1. scibot 03 Aug 2023
  
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  DOI: 10.1016/j.celrep.2023.112905
  
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sciencedirect.com/science/article/pii/S2211124723009166
Jun 2023
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The SWI/SNF chromatin remodeling complexes BAF and PBAF differentially regulate epigenetic transitions in exhausted CD8+ T cells

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1. scibot 23 Jun 2023
  
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  DOI: 10.1016/j.immuni.2023.05.008
  
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sciencedirect.com/science/article/pii/S107476132300225X
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Loss of PBAF promotes expansion and effector differentiation of CD8+ T cells during chronic viral infection and cancer

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1. scibot 21 Jun 2023
  
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  DOI: 10.1016/j.celrep.2023.112649
  
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sciencedirect.com/science/article/pii/S2211124723006605
May 2023
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Tumor eradication by hetIL-15 locoregional therapy correlates with an induced intratumoral CD103intCD11b+ dendritic cell population

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1. scibot 13 May 2023
  
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  DOI: 10.1016/j.celrep.2023.112501
  
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sciencedirect.com/science/article/pii/S2211124723005120
Jan 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Lymphatic PD-L1 Expression Restricts Tumor-Specific CD8+ T-cell Responses

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1. scibot 12 Jan 2023
  
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  DOI: 10.1158/0008-5472.CAN-21-0633
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9398148/
Dec 2022
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Mucosal exposure to non-tuberculous mycobacteria elicits B cell-mediated immunity against pulmonary tuberculosis

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1. scibot 18 Dec 2022
  
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  DOI: 10.1016/j.celrep.2022.111783
  
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sciencedirect.com/science/article/pii/S2211124722016710
Jun 2022
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BCL6-dependent TCF-1+ progenitor cells maintain effector and helper CD4+ T cell responses to persistent antigen

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1. scibot 03 Jun 2022
  
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  DOI: 10.1016/j.immuni.2022.05.003
  
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sciencedirect.com/science/article/pii/S1074761322002230
Nov 2021
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CXCL10 chemokine regulates heterogeneity of the CD8+ T cell response and viral set point during chronic infection

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1. scibot 30 Nov 2021
  
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  DOI: 10.1016/j.immuni.2021.11.002
  
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sciencedirect.com/science/article/pii/S1074761321004933
Oct 2021
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Cold exposure protects from neuroinflammation through immunologic reprogramming

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1. scibot 23 Oct 2021
  
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  DOI: 10.1016/j.cmet.2021.10.002
  
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sciencedirect.com/science/article/pii/S1550413121004800
Aug 2021
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Untitled document

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1. scibot 10 Aug 2021
  
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  RRID:AB_2565937
  
  DOI: 10.1016/j.immuni.2018.10.009
  
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sciencedirect.com/science/article/pii/S1074761318304746
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Developmental Analysis of Bone Marrow Neutrophils Reveals Populations Specialized in Expansion, Trafficking, and Effector Functions

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1. scibot 08 Aug 2021
  
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  DOI: 10.1016/j.immuni.2018.02.002
  
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sciencedirect.com/science/article/pii/S1074761318300384
Jul 2021
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Developmental Analysis of Bone Marrow Neutrophils Reveals Populations Specialized in Expansion, Trafficking, and Effector Functions

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1. scibot 27 Jul 2021
  
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  DOI: 10.1016/j.immuni.2018.02.002
  
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  RRIDCUR:Unrecognized RRID:AB_2565937
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sciencedirect.com/science/article/pii/S1074761318300384
May 2021
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Two sequential activation modules control the differentiation of protective T helper-1 (Th1) cells

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1. scibot 07 May 2021
  
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  DOI: 10.1016/j.immuni.2021.03.006
  
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sciencedirect.com/science/article/pii/S1074761321001187
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Uncoupling of macrophage inflammation from self-renewal modulates host recovery from respiratory viral infection

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1. scibot 05 May 2021
  
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  DOI: 10.1016/j.immuni.2021.04.001
  
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sciencedirect.com/science/article/pii/S1074761321001382
Jan 2021
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Application of dual Nr4a1-GFP Nr4a3-Tocky reporter mice to study T cell receptor signaling by flow cytometry

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1. scibot 26 Jan 2021
  
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  DOI: 10.1016/j.xpro.2020.100284
  
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  RRID:AB_2565937 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2666166720302719
Sep 2020
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Early Fate Defines Microglia and Non-parenchymal Brain Macrophage Development

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1. scibot 17 Sep 2020
  
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  DOI: 10.1016/j.cell.2020.03.021
  
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  RRID:AB_2565937 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S009286742030283X
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Developmental Relationships of Four Exhausted CD8+ T Cell Subsets Reveals Underlying Transcriptional and Epigenetic Landscape Control Mechanisms

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1. scibot 07 Sep 2020
  
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  DOI: 10.1016/j.immuni.2020.04.014
  
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  RRID:AB_2565937 RRIDCUR:Validated
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pmc.ncbi.nlm.nih.gov/articles/PMC8360766/