40 Matching Annotations
  1. Last 7 days
  2. www.sciencedirect.com www.sciencedirect.com
    LAG-3 sustains TOX expression and regulates the CD94/NKG2-Qa-1b axis to govern exhausted CD8 T cell NK receptor expression and cytotoxicity
    1
    1. scibot 20 Aug 2024
      AB_2571953

      DOI: 10.1016/j.cell.2024.07.018

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    sciencedirect.com/science/article/pii/S0092867424007785
  3. May 2024
  4. www.sciencedirect.com www.sciencedirect.com
    A RIPK1-specific PROTAC degrader achieves potent antitumor activity by enhancing immunogenic cell death
    1
    1. scibot 24 May 2024
      RRID:AB_2571953

      DOI: 10.1016/j.immuni.2024.04.025

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    sciencedirect.com/science/article/pii/S1074761324002309
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    Immunotherapy-activated T cells recruit and skewlate-stage activated M1-like macrophagesthat are critical for therapeutic efficacy
    1
    1. scibot 17 May 2024
      RRID:AB_2571953

      DOI: 10.1016/j.ccell.2024.04.011

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    sciencedirect.com/science/article/pii/S1535610824001351
  6. Mar 2024
  7. www.sciencedirect.com www.sciencedirect.com
    Acetyl-CoA carboxylase obstructs CD8+ T cell lipid utilization in the tumor microenvironment
    2
    1. scibot 15 Mar 2024
      RRID:AB_2571953

      DOI: 10.1016/j.cmet.2024.02.009

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    2. scibot 15 Mar 2024
      RRID:AB_2571953

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    sciencedirect.com/science/article/pii/S155041312400055X
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    SMARCA4 is a haploinsufficient B cell lymphoma tumor suppressor that fine-tunes centrocyte cell fate decisions
    2
    1. scibot 08 Mar 2024
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      DOI: 10.1016/j.ccell.2024.02.011

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    2. scibot 08 Mar 2024
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    sciencedirect.com/science/article/pii/S1535610824000552
  9. Jan 2024
  10. aacrjournals.org aacrjournals.org
    Formate supplementation enhances anti-tumor CD8+ T cell fitness and efficacy of PD-1 blockade
    1
    1. scibot 11 Jan 2024
      RRID:AB_2571953

      DOI: 10.1158/2159-8290.CD-22-1301

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    aacrjournals.org/cancerdiscovery/article/13/12/2566/731588/Formate-Supplementation-Enhances-Antitumor-CD8-T
  11. Dec 2023
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    The MHC-E peptide ligands for checkpoint CD94/NKG2A are governed by inflammatory signals, whereas LILRB1/2 receptors are peptide indifferent
    1
    1. scibot 20 Dec 2023
      RRID:AB_2571953

      DOI: 10.1016/j.celrep.2023.113516

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    sciencedirect.com/science/article/pii/S2211124723015280
  13. 52.53.155.43 52.53.155.43
    cd-22-1301-html.html
    1
    1. scibot 01 Dec 2023
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      DOI: 10.1158/2159-8290.cd-22-1301

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  14. Oct 2023
  15. 52.53.155.43 52.53.155.43
    Antigen presentation by tumor-associated macrophages mediates progenitor to terminal exhaustion transition in GBM and other solid tumors
    1
    1. scibot 14 Oct 2023
      RRID:AB_2571953

      DOI: 10.1101/2023.08.11.553007

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  16. Aug 2023
  17. www.sciencedirect.com www.sciencedirect.com
    The pseudokinase Trib1 regulates the transition of exhausted T cells to a KLR+ CD8+ effector state, and its deletion improves checkpoint blockade
    1
    1. scibot 03 Aug 2023
      RRID:AB_2571953

      DOI: 10.1016/j.celrep.2023.112905

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    sciencedirect.com/science/article/pii/S2211124723009166
  18. Jun 2023
  19. www.sciencedirect.com www.sciencedirect.com
    The SWI/SNF chromatin remodeling complexes BAF and PBAF differentially regulate epigenetic transitions in exhausted CD8+ T cells
    1
    1. scibot 23 Jun 2023
      RRID:AB_2571953

      DOI: 10.1016/j.immuni.2023.05.008

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    sciencedirect.com/science/article/pii/S107476132300225X
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    Quantitative control of Ets1 dosage by a multi-enhancer hub promotes Th1 cell differentiation and protects from allergic inflammation
    1
    1. scibot 01 Jun 2023
      RRID:AB_2571953

      DOI: 10.1016/j.immuni.2023.05.004

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    sciencedirect.com/science/article/pii/S1074761323002212
  21. May 2023
  22. www.sciencedirect.com www.sciencedirect.com
    Glioblastoma cell fate is differentially regulated by the microenvironments of the tumor bulk and infiltrative margin
    1
    1. scibot 11 May 2023
      RRID:AB_2571953

      DOI: 10.1016/j.celrep.2023.112472

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    sciencedirect.com/science/article/pii/S2211124723004837
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    M cell maturation and cDC activation determine the onset of adaptive immune priming in the neonatal Peyer’s patch
    1
    1. scibot 03 May 2023
      RRID:AB_2571953

      DOI: 10.1016/j.immuni.2023.04.002

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    sciencedirect.com/science/article/pii/S107476132300170X
  24. Apr 2023
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    cDC1 coordinate innate and adaptive responses in the omentum required for T cell priming and memory
    1
    1. scibot 05 Apr 2023
      RRID:AB_2571953

      DOI: 10.1126/sciimmunol.abq7432

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    ncbi.nlm.nih.gov/pmc/articles/PMC9835709/
  26. Mar 2023
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Original research: Invasive margin tissue-resident macrophages of high CD163 expression impede responses to T cell-based immunotherapy
    1
    1. scibot 18 Mar 2023
      RRID:AB_2571953

      DOI: 10.1136/jitc-2022-006433

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    ncbi.nlm.nih.gov/pmc/articles/PMC10016286/
  28. Feb 2023
  29. www.sciencedirect.com www.sciencedirect.com
    OX40 agonism enhances PD-L1 checkpoint blockade by shifting the cytotoxic T cell differentiation spectrum
    1
    1. scibot 16 Feb 2023
      RRID:AB_2571953

      DOI: 10.1016/j.xcrm.2023.100939

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    sciencedirect.com/science/article/pii/S2666379123000319
  30. www.sciencedirect.com www.sciencedirect.com
    Human IRF1 governs macrophagic IFN-γ immunity to mycobacteria
    1
    1. scibot 03 Feb 2023
      RRID:AB_2571953

      DOI: 10.1016/j.cell.2022.12.038

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    sciencedirect.com/science/article/pii/S0092867422015811
  31. Jan 2023
  32. www.sciencedirect.com www.sciencedirect.com
    Small intestine and colon tissue-resident memory CD8+ T cells exhibit molecular heterogeneity and differential dependence on Eomes
    1
    1. scibot 28 Jan 2023
      RRID:AB_2571953

      DOI: 10.1016/j.immuni.2022.12.007

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    sciencedirect.com/science/article/pii/S1074761322006434
  33. Dec 2022
  34. aacrjournals.org aacrjournals.org
    Stress-mediated attenuation of translation undermines T-cell activity in cancer
    1
    1. scibot 03 Dec 2022
      RRID:AB_2571953

      DOI: 10.1158/0008-5472.CAN-22-1744

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    aacrjournals.org/cancerres/article/82/23/4386/710692/Stress-Mediated-Attenuation-of-Translation
  35. 52.53.155.43 52.53.155.43
    can-22-1744-html.html
    1
    1. scibot 01 Dec 2022
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      DOI: 10.1158/0008-5472.can-22-1744

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    52.53.155.43/ad84fbadafd7207ef01b11f7e83790e81459d855/can-22-1744-html.html
  36. Oct 2022
  37. 52.53.155.43 52.53.155.43
    IgA deficiency destabilizes immunological homeostasis towards intestinal microbiota and increases the risk of systemic immune dysregulation
    1
    1. scibot 27 Oct 2022
      AB_2571953

      DOI: 10.1101/2021.08.20.21261620

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    52.53.155.43/62b31cea1ac090bac2ebe32e4dfd3474fee27f84/2021.08.20.21261620v1.full-html.html
  38. Aug 2022
  39. www.sciencedirect.com www.sciencedirect.com
    Lymphatic migration of unconventional T cells promotes site-specific immunity in distinct lymph nodes
    1
    1. scibot 26 Aug 2022
      RRID:AB_2571953

      DOI: 10.1016/j.immuni.2022.07.019

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    sciencedirect.com/science/article/pii/S1074761322003545
  40. Nov 2021
  41. www.sciencedirect.com www.sciencedirect.com
    CXCL10 chemokine regulates heterogeneity of the CD8+ T cell response and viral set point during chronic infection
    1
    1. scibot 30 Nov 2021
      RRID:AB_2571953

      DOI: 10.1016/j.immuni.2021.11.002

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    sciencedirect.com/science/article/pii/S1074761321004933
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    Autotaxin impedes anti-tumor immunity by suppressing chemotaxis and tumor infiltration of CD8+ T cells
    1
    1. scibot 17 Nov 2021
      RRID:AB_2571953

      DOI: 10.1016/j.celrep.2021.110013

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    sciencedirect.com/science/article/pii/S2211124721014959
  43. Sep 2021
  44. www.sciencedirect.com www.sciencedirect.com
    Antigen dominance hierarchies shape TCF1+ progenitor CD8 T cell phenotypes in tumors
    1
    1. scibot 18 Sep 2021
      AB_2571953

      DOI: 10.1016/j.cell.2021.08.020

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    sciencedirect.com/science/article/pii/S0092867421009946
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    Conventional type I dendric cells maintain a reservoir of proliferative tumor-antigen specific TCF-1+ CD8+ T cells in tumor-draining lymph nodes
    1
    1. scibot 17 Sep 2021
      RRID:AB_2571953

      DOI: 10.1016/j.immuni.2021.08.026

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    sciencedirect.com/science/article/pii/S1074761321003605
  46. May 2021
  47. www.sciencedirect.com www.sciencedirect.com
    Role of nuclear localization in the regulation and function of T-bet and Eomes in exhausted CD8 T cells
    1
    1. scibot 12 May 2021
      RRID:AB_2571953

      DOI: 10.1016/j.celrep.2021.109120

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    sciencedirect.com/science/article/pii/S2211124721004599
  48. Apr 2021
  49. www.sciencedirect.com www.sciencedirect.com
    Multi-phenotype CRISPR-Cas9 Screen Identifies p38 Kinase as a Target for Adoptive Immunotherapies
    1
    1. scibot 17 Apr 2021
      RRID:AB_2571953

      DOI: 10.1016/j.ccell.2020.05.004

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    sciencedirect.com/science/article/pii/S1535610820302543
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    In vivo CD8+ T cell CRISPR screening reveals control by Fli1 in infection and cancer
    1
    1. scibot 11 Apr 2021
      RRID:AB_2571953

      DOI: 10.1016/j.cell.2021.02.019

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    ncbi.nlm.nih.gov/pmc/articles/PMC8054351/
  51. Oct 2020
  52. www.sciencedirect.com www.sciencedirect.com
    In Vitro Recapitulation of Murine Thymopoiesis from Single Hematopoietic Stem Cells
    1
    1. scibot 31 Oct 2020
      RRID:AB_2571953

      DOI: 10.1016/j.celrep.2020.108320

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    sciencedirect.com/science/article/pii/S2211124720313097
  53. Sep 2020
  54. www.sciencedirect.com www.sciencedirect.com
    The PD-1 Pathway Regulates Development and Function of Memory CD8+ T Cells following Respiratory Viral Infection
    1
    1. scibot 16 Sep 2020
      RRID:AB_2571953

      DOI: 10.1016/j.celrep.2020.107827

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    sciencedirect.com/science/article/pii/S2211124720308081
  55. www.cell.com www.cell.com
    Survival of Single Positive Thymocytes Depends upon Developmental Control of RIPK1 Kinase Signaling by the IKK Complex Independent of NF-κB
    1
    1. scibot 08 Sep 2020
      RRID:AB_2571953

      DOI: 10.1016/j.immuni.2019.01.004

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    cell.com/immunity/abstract/S1074-7613(19)30004-4
  56. Jan 2020
  57. www.sciencedirect.com www.sciencedirect.com
    TCF-1-Centered Transcriptional Network Drives an Effector versus Exhausted CD8 T Cell-Fate Decision
    1
    1. scibot 13 Jan 2020
      RRID:AB_2571953

      DOI: 10.1016/j.immuni.2019.09.013

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    sciencedirect.com/science/article/pii/S1074761319304091
  58. www.sciencedirect.com www.sciencedirect.com
    Robust Iterative Stimulation with Self-Antigens Overcomes CD8+ T Cell Tolerance to Self- and Tumor Antigens
    1
    1. scibot 13 Jan 2020
      RRID:AB_2571953

      DOI: 10.1016/j.celrep.2019.08.038

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    sciencedirect.com/science/article/pii/S2211124719310782
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    Interstitial Migration of CD8αβ T Cells in the Small Intestine Is Dynamic and Is Dictated by Environmental Cues
    1
    1. scibot 13 Jan 2020
      RRID:AB_2571953

      DOI: 10.1016/j.celrep.2019.02.034

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    sciencedirect.com/science/article/pii/S2211124719302050
  60. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 12 Jan 2020
      RRID:AB_2571953

      DOI: 10.1016/j.immuni.2019.01.004

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    sciencedirect.com/science/article/pii/S1074761319300044
  61. Nov 2018
  62. www.sciencedirect.com www.sciencedirect.com
    T Cells in Nonlymphoid Tissues Give Rise to Lymph-Node-Resident Memory T Cells
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      RRID:AB_2571953
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    sciencedirect.com/science/article/pii/S1074761318300360