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Oct 2025
www.biorxiv.org www.biorxiv.org

Genotoxic antibody-drug conjugates combined with Bcl-xL inhibitors enhance therapeutic efficacy in metastatic castration-resistant prostate cancer

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  DOI: 10.1101/2025.09.05.674562
  
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biorxiv.org/content/10.1101/2025.09.05.674562v1
Sep 2025
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Genotoxic antibody-drug conjugates combined with Bcl-xL inhibitors enhance therapeutic efficacy in metastatic castration-resistant prostate cancer

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1. scibot 22 Sep 2025
  
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  DOI: 10.1101/2025.09.05.674562
  
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biorxiv.org/content/10.1101/2025.09.05.674562v1
Aug 2025
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Protocol for the spatiotemporal profiling of RNA within nuclear compartments in human cell lines using SLAM-RT&Tag

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  DOI: 10.1016/j.xpro.2025.104017
  
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sciencedirect.com/science/article/pii/S266616672500423X
Jul 2025
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CRISPR-based screening identifies the role of KRAB-containing transcription factors ZIM3 and ZNF394 in human major zygotic genome activation

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1. scibot 22 Jul 2025
  
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  DOI: 10.1016/j.celrep.2025.116015
  
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cell.com/cell-reports/fulltext/S2211-1247(25)00786-7
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Mex3a-dependent post-transcriptional silencing ensures olfactory receptor diversity and axon guidance specificity

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  DOI: 10.1016/j.celrep.2025.115979
  
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cell.com/cell-reports/fulltext/S2211-1247(25)00750-8
Jun 2025
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Altered cofactor recruitment and nucleosome dynamics underlie bisphenol A’s impact on ERα-mediated transcriptional bursting

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1. scibot 28 Jun 2025
  
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  DOI: 10.1016/j.isci.2025.112864
  
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sciencedirect.com/science/article/pii/S2589004225011253
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The SIN3A histone deacetylase complex is required for a complete transcriptional response to hypoxia

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  DOI: 10.1101/182691
  
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biorxiv.org/content/10.1101/182691v1
Apr 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

p53 regulates DREAM complex-mediated repression in a p21-independent manner

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1. scibot 18 Apr 2025
  
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  DOI: 10.1038/s44318-025-00402-7
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12000331/
Mar 2025
academic.oup.com academic.oup.com

Dynamic regulation of murine RNA polymerase III transcription during heat shock stress

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1. scibot 25 Mar 2025
  
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  DOI: 10.1093/genetics/iyaf042
  
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academic.oup.com/genetics/advance-article/doi/10.1093/genetics/iyaf042/8085024
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Profiling transcriptome composition and dynamics within nuclear compartments using SLAM-RT&Tag

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1. scibot 13 Mar 2025
  
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  DOI: 10.1016/j.molcel.2025.02.012
  
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sciencedirect.com/science/article/pii/S1097276525001431
Feb 2025
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Deletion of a single CTCF motif at the boundary of a chromatin domain with three FGF genes disrupts gene expression and embryonic development

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1. scibot 27 Feb 2025
  
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  DOI: 10.1016/j.devcel.2025.02.002
  
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sciencedirect.com/science/article/pii/S1534580725000644
52.53.155.43 52.53.155.43

Dynamic regulation of RNA Polymerase III transcription in mouse embryonic stem cells during heat shock stress

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1. scibot 07 Feb 2025
  
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  DOI: 10.1101/2024.11.28.625959
  
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52.53.155.43/036271772ffeeb8f5a4cfd38744d991b76301855/2024.11.28.625959.full-html.html
Jan 2025
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Zebrafish glial-vascular interactions progressively expand over the course of brain development

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1. scibot 03 Jan 2025
  
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  DOI: 10.1016/j.isci.2024.111549
  
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sciencedirect.com/science/article/pii/S2589004224027767
Dec 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Expanding GABAergic Neuronal Diversity in iPSC-Derived Disease Models

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1. scibot 28 Dec 2024
  
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  DOI: 10.1101/2024.12.03.626438
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11642846/
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FcRn-dependent IgG accumulation in adipose tissue unmasks obesity pathophysiology

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1. scibot 19 Dec 2024
  
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  DOI: 10.1016/j.cmet.2024.11.001
  
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sciencedirect.com/science/article/pii/S1550413124004479
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Regulation of human interferon signaling by transposon exonization

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1. scibot 14 Dec 2024
  
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  DOI: 10.1016/j.cell.2024.11.016
  
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sciencedirect.com/science/article/pii/S0092867424013333
Nov 2024
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Spatial transcriptomic landscape unveils immunoglobin-associated senescence as a hallmark of aging

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1. scibot 16 Nov 2024
  
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  DOI: 10.1016/j.cell.2024.10.019
  
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sciencedirect.com/science/article/pii/S0092867424012017
Aug 2024
www.cell.com www.cell.com

Definition of a small core transcriptional circuit regulated by AML1-ETO

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1. scibot 02 Aug 2024
  
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  Rabbit α-Mouse IgG
  
  DOI: 10.1016/j.molcel.2020.12.005
  
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cell.com/molecular-cell/fulltext/S1097-2765(20)30897-2
Apr 2024
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Chromatin landscape instructs precise transcription factor regulome during embryonic lineage specification

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1. scibot 23 Apr 2024
  
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  DOI: 10.1016/j.celrep.2024.114136
  
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sciencedirect.com/science/article/pii/S2211124724004649
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Defining a TFAP2C-centered transcription factor network during murine peri-implantation

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  DOI: 10.1016/j.devcel.2024.03.015
  
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  DOI: 10.1016/j.devcel.2024.03.015
  
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sciencedirect.com/science/article/pii/S1534580724001850
Mar 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A Cluster of Evolutionarily Recent KRAB Zinc Finger Proteins Protects Cancer Cells from Replicative Stress-Induced Inflammation

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1. scibot 17 Mar 2024
  
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  DOI: 10.1158/0008-5472.CAN-23-1237
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10940857/
Jan 2024
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DNA-guided transcription factor cooperativity shapes face and limb mesenchyme

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1. scibot 23 Jan 2024
  
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  DOI: 10.1016/j.cell.2023.12.032
  
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  DOI: 10.1016/j.cell.2023.12.032
  
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sciencedirect.com/science/article/pii/S0092867423014381
Nov 2023
www.nature.com www.nature.com

Scalable single-cell profiling of chromatin modifications with sciCUT&Tag

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1. scibot 17 Nov 2023
  
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  DOI: 10.1038/s41596-023-00905-9
  
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nature.com/articles/s41596-023-00905-9
Oct 2023
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The histone chaperone ANP32B regulates chromatin incorporation of the atypical human histone variant macroH2A

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1. scibot 27 Oct 2023
  
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  DOI: 10.1016/j.celrep.2023.113300
  
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sciencedirect.com/science/article/pii/S2211124723013128
Jul 2023
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Chromatin regulation of transcriptional enhancers and cell fate by the Sotos syndrome gene NSD1

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1. scibot 06 Jul 2023
  
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  DOI: 10.1016/j.molcel.2023.06.007
  
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sciencedirect.com/science/article/pii/S1097276523004306
Apr 2023
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GAGA-associated factor fosters loop formation in the Drosophila genome

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1. scibot 27 Apr 2023
  
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  DOI: 10.1016/j.molcel.2023.03.011
  
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sciencedirect.com/science/article/pii/S1097276523001685
Feb 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Decorating chromatin for enhanced genome editing using CRISPR-Cas9

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1. scibot 04 Feb 2023
  
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  DOI: 10.1073/pnas.2204259119
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9894255/
Nov 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Mechanisms governing target search and binding dynamics of hypoxia-inducible factors

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1. scibot 30 Nov 2022
  
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  Abcam, #ab46540
  
  DOI: 10.7554/eLife.75064
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9681212/
Oct 2022
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Topoisomerases I and II facilitate condensin DC translocation to organize and repress X chromosomes in C. elegans

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1. scibot 27 Oct 2022
  
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  DOI: 10.1016/j.molcel.2022.10.002
  
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sciencedirect.com/science/article/pii/S1097276522009595
Jul 2022
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RPA1 controls chromatin architecture and maintains lipid metabolic homeostasis

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  DOI: 10.1016/j.celrep.2022.111071
  
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sciencedirect.com/science/article/pii/S2211124722008695
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Efficient and strand-specific profiling of replicating chromatin with enrichment and sequencing of protein-associated nascent DNA in mammalian cells

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1. scibot 09 Jul 2022
  
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  DOI: 10.1038/s41596-021-00520-6
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9261918/
Jun 2022
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MacroH2As regulate enhancer-promoter contacts affecting enhancer activity and sensitivity to inflammatory cytokines

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1. scibot 22 Jun 2022
  
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  DOI: 10.1016/j.celrep.2022.110988
  
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sciencedirect.com/science/article/pii/S2211124722007744
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Mapping cis-regulatory elements in human neurons links psychiatric disease heritability and activity-regulated transcriptional programs

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1. scibot 03 Jun 2022
  
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  DOI: 10.1016/j.celrep.2022.110877
  
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sciencedirect.com/science/article/pii/S2211124722006520
Apr 2022
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Functional elements of the cis-regulatory lincRNA-p21

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1. scibot 20 Apr 2022
  
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  DOI: 10.1016/j.celrep.2022.110687
  
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sciencedirect.com/science/article/pii/S2211124722004454
Aug 2021
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Chromatin and transcription factor profiling in rare stem cell populations using CUT&Tag

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1. scibot 20 Aug 2021
  
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Enhancer decommissioning imposes an epigenetic barrier to sensory hair cell regeneration

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Red Blood Cell Invasion by the Malaria Parasite Is Coordinated by the PfAP2-I Transcription Factor

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Nascent RNA antagonizes the interaction of a set of regulatory proteins with chromatin

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A protocol for rapid degradation of endogenous transcription factors in mammalian cells and identification of direct regulatory targets

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TBL1XR1 Mutations Drive Extranodal Lymphoma by Inducing a Pro-tumorigenic Memory Fate

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Efficient chromatin accessibility mapping in situ by nucleosome-tethered tagmentation

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p53 Activates the Long Noncoding RNA Pvt1b to Inhibit Myc and Suppress Tumorigenesis

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Febrile Temperature Critically Controls the Differentiation and Pathogenicity of T Helper 17 Cells

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Efficient low-cost chromatin profiling with CUT&Tag

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Pioneer Factor-Nucleosome Binding Events during Differentiation Are Motif Encoded

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LSD1 Inhibition Promotes Epithelial Differentiation through Derepression of Fate-Determining Transcription Factors

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Improved CUT&RUN chromatin profiling tools

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TALE factors use two distinct functional modes to control an essential zebrafish gene expression program

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A LINE1-Nucleolin Partnership Regulates Early Development and ESC Identity

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The Transcriptionally Permissive Chromatin State of Embryonic Stem Cells Is Acutely Tuned to Translational Output

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The SIN3A histone deacetylase complex is required for a complete transcriptional response to hypoxia

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MYC Controls Human Pluripotent Stem Cell Fate Decisions through Regulation of Metabolic Flux

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An Hdac1/Rpd3-Poised Circuit Balances Continual Self-Renewal and Rapid Restriction of Developmental Potential during Asymmetric Stem Cell Division

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RNA Binding to CBP Stimulates Histone Acetylation and Transcription

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