66 Matching Annotations
  1. Last 7 days
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The annotation of GBA1 has been concealed by its protein-coding pseudogene GBAP1
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    1. scibot 02 Jul 2024
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      DOI: 10.1126/sciadv.adk1296

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    ncbi.nlm.nih.gov/pmc/articles/PMC11204300/
  3. link.springer.com link.springer.com
    Spatially resolved epigenome sequencing via Tn5 transposition and deterministic DNA barcoding in tissue
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    1. scibot 30 Jun 2024
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      DOI: 10.1038/s41596-024-01013-y

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    link.springer.com/article/10.1038/s41596-024-01013-y
  4. May 2024
  5. www.sciencedirect.com www.sciencedirect.com
    MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons
    1
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      DOI: 10.1016/j.neuron.2024.04.007

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    sciencedirect.com/science/article/pii/S0896627324002459
  6. Apr 2024
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    SAFB restricts contact domain boundaries associated with L1 chimeric transcription
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    1. scibot 11 Apr 2024
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    sciencedirect.com/science/article/pii/S1097276524002314
  8. Mar 2024
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    Nuclear microRNA-mediated transcriptional control determines adult microglial homeostasis and brain function
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    sciencedirect.com/science/article/pii/S2211124724002924
  10. Feb 2024
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    EZH2 Inhibition Promotes Tumor Immunogenicity in Lung Squamous Cell Carcinomas
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    ncbi.nlm.nih.gov/pmc/articles/PMC10863487/
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    FOXA1 forms biomolecular condensates that unpack condensed chromatin to function as a pioneer factor
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    1. scibot 09 Feb 2024
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    sciencedirect.com/science/article/abs/pii/S1097276523009656
  13. Jan 2024
  14. www.sciencedirect.com www.sciencedirect.com
    PCGF6 controls murine Tuft cell differentiation via H3K9me2 modification independently of Polycomb repression
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    sciencedirect.com/science/article/pii/S1534580723006962
  15. Nov 2023
  16. www.nature.com www.nature.com
    Scalable single-cell profiling of chromatin modifications with sciCUT&Tag
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      DOI: 10.1038/s41596-023-00905-9

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    nature.com/articles/s41596-023-00905-9
  17. www.science.org www.science.org
    LINE-1 retrotransposons drive human neuronal transcriptome complexity and functional diversification
    1
    1. scibot 17 Nov 2023
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      DOI: 10.1126/sciadv.adh9543

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  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    LINE-1 retrotransposons drive human neuronal transcriptome complexity and functional diversification
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    ncbi.nlm.nih.gov/pmc/articles/PMC10619931/
  19. Oct 2023
  20. www.sciencedirect.com www.sciencedirect.com
    Gcn5- and Bre1-mediated Set2 degradation promotes chronological aging of Saccharomyces cerevisiae
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    sciencedirect.com/science/article/pii/S2211124723011981
  21. www.embopress.org www.embopress.org
    Hypoxia activates SREBP2 through Golgi disassembly in bone marrow-derived monocytes for enhanced tumor growth
    1
    1. scibot 03 Oct 2023
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      DOI: 10.15252/embj.2023114032

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    embopress.org/doi/10.15252/embj.2023114032
  22. Sep 2023
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Histone bivalency regulates the timing of cerebellar granule cell development
    1
    1. scibot 17 Sep 2023
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      DOI: 10.1101/gad.350594.123

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    ncbi.nlm.nih.gov/pmc/articles/PMC10499015/
  24. Jun 2023
  25. www.sciencedirect.com www.sciencedirect.com
    Pyruvate metabolism controls chromatin remodeling during CD4+ T cell activation
    1
    1. scibot 03 Jun 2023
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    sciencedirect.com/science/article/pii/S2211124723005946
  26. May 2023
  27. www.biorxiv.org www.biorxiv.org
    L1 retrotransposons drive human neuronal transcriptome complexity and functional diversification
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    1. scibot 04 May 2023
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      DOI: 10.1101/2023.03.04.531072

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    biorxiv.org/content/10.1101/2023.03.04.531072v1
  28. Apr 2023
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    Evolutionarily distinct and sperm-specific supersized chromatin loops are marked by Helitron transposons in Xenopus tropicalis
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    sciencedirect.com/science/article/pii/S2211124723001626
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    Transient suppression of SUMOylation in embryonic stem cells generates embryo-like structures
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    sciencedirect.com/science/article/pii/S2211124723003911
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    Targeting the mevalonate pathway suppresses ARID1A-inactivated cancers by promoting pyroptosis
    1
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      DOI: 10.1016/j.ccell.2023.03.002

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    sciencedirect.com/science/article/pii/S1535610823000508
  32. Mar 2023
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    KDM6A Loss Triggers an Epigenetic Switch That Disrupts Urothelial Differentiation and Drives Cell Proliferation in Bladder Cancer
    1
    1. scibot 18 Mar 2023
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      DOI: 10.1158/0008-5472.CAN-22-1444

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  34. www.biorxiv.org www.biorxiv.org
    Histone bivalency regulates the timing of cerebellar granule cell development
    1
    1. scibot 03 Mar 2023
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      DOI: 10.1101/2023.02.02.526881

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    biorxiv.org/content/10.1101/2023.02.02.526881v1
  35. Feb 2023
  36. www.sciencedirect.com www.sciencedirect.com
    Bat pluripotent stem cells reveal unusual entanglement between host and viruses
    1
    1. scibot 23 Feb 2023
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    sciencedirect.com/science/article/pii/S0092867423000417
  37. Jan 2023
  38. www.sciencedirect.com www.sciencedirect.com
    Multi-omics profiling visualizes dynamics of cardiac development and functions
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    sciencedirect.com/science/article/pii/S2211124722017909
  39. Dec 2022
  40. www.sciencedirect.com www.sciencedirect.com
    SETD1A regulates transcriptional pause release of heme biosynthesis genes in leukemia
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    sciencedirect.com/science/article/pii/S2211124722016059
  41. Nov 2022
  42. www.sciencedirect.com www.sciencedirect.com
    Tip60-mediated H2A.Z acetylation promotes neuronal fate specification and bivalent gene activation
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    sciencedirect.com/science/article/abs/pii/S1097276522010644
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    Metabolic regulation by p53 prevents R-loop-associated genomic instability
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    sciencedirect.com/science/article/pii/S2211124722014292
  44. Mar 2022
  45. www.sciencedirect.com www.sciencedirect.com
    The BTB transcription factors ZBTB11 and ZFP131 maintain pluripotency by repressing pro-differentiation genes
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    1. scibot 16 Mar 2022
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    sciencedirect.com/science/article/pii/S2211124722002601
  46. asbmr.onlinelibrary.wiley.com asbmr.onlinelibrary.wiley.com
    Transcription factor Hhex negatively regulates osteoclast differentiation by controlling cyclin-dependent kinase inhibitors
    1
    1. scibot 02 Mar 2022
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      DOI: 10.1002/jbm4.10608

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    asbmr.onlinelibrary.wiley.com/doi/10.1002/jbm4.10608
  47. Feb 2022
  48. www.sciencedirect.com www.sciencedirect.com
    Activation-induced chromatin reorganization in neurons depends on HDAC1 activity
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    1. scibot 16 Feb 2022
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      DOI: 10.1016/j.celrep.2022.110352

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    sciencedirect.com/science/article/pii/S2211124722000687
  49. Dec 2021
  50. elifesciences.org elifesciences.org
    5-Hydroxymethylcytosine-mediated active demethylation is required for mammalian neuronal differentiation and function
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    1. scibot 22 Dec 2021
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      DOI: 10.7554/eLife.66973

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    2. scibot 22 Dec 2021
      RRID:AB_2615077Active

      DOI: 10.7554/eLife.66973

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    elifesciences.org/articles/66973
  51. Nov 2021
  52. www.sciencedirect.com www.sciencedirect.com
    Cell division- and DNA replication-free reprogramming of somatic nuclei for embryonic transcription
    1
    1. scibot 04 Nov 2021
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      DOI: 10.1016/j.isci.2021.103290

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    sciencedirect.com/science/article/pii/S2589004221012591
  53. Oct 2021
  54. www.sciencedirect.com www.sciencedirect.com
    Increased ACTL6A occupancy within mSWI/SNF chromatin remodelers drives human squamous cell carcinoma
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    sciencedirect.com/science/article/pii/S1097276521008340
  55. www.sciencedirect.com www.sciencedirect.com
    A cis-acting structural variation at the ZNF558 locus controls a gene regulatory network in human brain development
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      DOI: 10.1016/j.stem.2021.09.008

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    sciencedirect.com/science/article/pii/S1934590921003842
  56. Sep 2021
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HBO1-MLL interaction promotes AF4/ENL/P-TEFb-mediated leukemogenesis
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      DOI: 10.7554/eLife.65872

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    ncbi.nlm.nih.gov/pmc/articles/PMC8387021/
  58. Aug 2021
  59. www.sciencedirect.com www.sciencedirect.com
    KDM5A suppresses PML-RARα target gene expression and APL differentiation through repressing H3K4me2
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    1. scibot 31 Aug 2021
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      DOI: 10.1182/bloodadvances.2020002819

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    sciencedirect.com/science/article/pii/S2473952921004171
  60. www.sciencedirect.com www.sciencedirect.com
    Enhancer decommissioning imposes an epigenetic barrier to sensory hair cell regeneration
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      DOI: 10.1016/j.devcel.2021.07.003

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    sciencedirect.com/science/article/pii/S1534580721005591
  61. Jul 2021
  62. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 31 Jul 2021
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      DOI: 10.1016/j.ccell.2018.11.014

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    sciencedirect.com/science/article/pii/S153561081830535X
  63. Jun 2021
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SIRT1 regulates sphingolipid metabolism and neural differentiation of mouse embryonic stem cells through c-Myc-SMPDL3B
    1
    1. scibot 26 Jun 2021
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      DOI: 10.7554/eLife.67452

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    ncbi.nlm.nih.gov/pmc/articles/PMC8216717/
  65. May 2021
  66. www.sciencedirect.com www.sciencedirect.com
    Chromatin accessibility governs the differential response of cancer and T cells to arginine starvation
    1
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      DOI: 10.1016/j.celrep.2021.109101

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    sciencedirect.com/science/article/pii/S2211124721004356
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    m6A Modification Prevents Formation of Endogenous Double-Stranded RNAs and Deleterious Innate Immune Responses during Hematopoietic Development
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    Stromal SOX2 Upregulation Promotes Tumorigenesis through the Generation of a SFRP1/2-Expressing Cancer-Associated Fibroblast Population
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      DOI: 10.1016/j.devcel.2020.10.014

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  69. Apr 2021
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    Integrated Metabolic and Epigenomic Reprograming by H3K27M Mutations in Diffuse Intrinsic Pontine Gliomas
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  71. Mar 2021
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    H3.3-K27M drives neural stem cell-specific gliomagenesis in a human iPSC-derived model
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  73. Feb 2021
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    The histone demethylase KDM5 is required for synaptic structure and function at the Drosophila neuromuscular junction
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  75. Sep 2020
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    Activation of CpG-Rich Promoters Mediated by MLL Drives MOZ-Rearranged Leukemia
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  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Large domains of heterochromatin direct the formation of short mitotic chromosome loops
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  78. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Loss of Extreme Long-Range Enhancers in Human Neural Crest Drives a Craniofacial Disorder
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  79. elifesciences.org elifesciences.org
    Systematic perturbation of retroviral LTRs reveals widespread long-range effects on human gene regulation
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    ZBTB1 Regulates Asparagine Synthesis and Leukemia Cell Response to L-Asparaginase
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  81. Jan 2020
  82. academic.oup.com academic.oup.com
    HUMAN TROPHOBLAST DIFFERENTIATION IS ASSOCIATED WITH PROFOUND GENE REGULATORY AND EPIGENETIC CHANGES
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      DOI: 10.1210/en.2019-00144

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    DNA Hypermethylation Encroachment at CpG Island Borders in Cancer Is Predisposed by H3K4 Monomethylation Patterns
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    Inhibiting Inflammation with Myeloid Cell-Specific Nanobiologics Promotes Organ Transplant Acceptance
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      DOI: 10.1016/j.immuni.2018.09.008

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  87. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Cooperation of PU.1 With IRF8 and NFATc1 Defines Chromatin Landscapes During RANKL‐Induced Osteoclastogenesis
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      DOI: 10.1002/jbmr.3689

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  88. Nov 2018
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    Examining the Roles of H3K4 Methylation States with Systematically Characterized Antibodies
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    Increased Lactate Secretion by Cancer Cells Sustains Non-cell-autonomous Adaptive Resistance to MET and EGFR Targeted Therapies
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    Identification of Therapeutic Targets in Rhabdomyosarcoma through Integrated Genomic, Epigenomic, and Proteomic Analyses
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    Promoter of lncRNA Gene PVT1 Is a Tumor-Suppressor DNA Boundary Element
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  94. Nov 2017
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    Aging Triggers Cytoplasmic Depletion and Nuclear Translocation of the E3 Ligase Mahogunin: A Function for Ubiquitin in Neuronal Survival
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      Curator: @chewbeccax

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    Mll3 and Mll4 Facilitate Enhancer RNA Synthesis and Transcription from Promoters Independently of H3K4 Monomethylation
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    Ciliary transcription factors and miRNAs precisely regulate Cp110 levels required for ciliary adhesions and ciliogenesis
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    A Multi-step Transcriptional and Chromatin State Cascade Underlies Motor Neuron Programming from Embryonic Stem Cells
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    Inheritable Silencing of Endogenous Genes by Hit-and-Run Targeted Epigenetic Editing
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