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  1. Last 7 days
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    Acute MeCP2 loss in adult mice reveals transcriptional and chromatin changes that precede neurological dysfunction and inform pathogenesis
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    sciencedirect.com/science/article/pii/S0896627324008067
  3. Dec 2024
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    Actin-based deformations of the nucleus control mouse multiciliated ependymal cell differentiation
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    sciencedirect.com/science/article/pii/S1534580724006737
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    Enforced activation of the CREB/KDM2B axis prevents alcohol-induced embryonic developmental delay
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    Epigenetic and Oncogenic Inhibitors Cooperatively Drive Differentiation and Kill KRAS-Mutant Colorectal Cancers
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    EZH2 inhibition enhances T cell immunotherapies by inducing lymphoma immunogenicity and improving T cell function
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    DNA hypomethylation promotes UHRF1-and SUV39H1/H2-dependent crosstalk between H3K18ub and H3K9me3 to reinforce heterochromatin states
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    sciencedirect.com/science/article/pii/S1097276524009146
  9. Nov 2024
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    Acute multi-level response to defective de novo chromatin assembly in S-phase
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    sciencedirect.com/science/article/pii/S1097276524008633
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    BRG1 programs PRC2-complex repression and controls oligodendrocyte differentiation and remyelination
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    pmc.ncbi.nlm.nih.gov/articles/PMC11040499/
  12. Oct 2024
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    HOXDeRNA activates a cancerous transcription program and super enhancers via genome-wide binding
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    Multiplexed chromatin immunoprecipitation sequencing for quantitative study of histone modifications and chromatin factors
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    H3.3 G34W Promotes Growth and Impedes Differentiation of Osteoblast-Like Mesenchymal Progenitors in Giant Cell Tumor of Bone
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    aacrjournals.org/cancerdiscovery/article/10/12/1968/2414/H3-3-G34W-Promotes-Growth-and-Impedes
  16. Sep 2024
  17. analyticalsciencejournals.onlinelibrary.wiley.com analyticalsciencejournals.onlinelibrary.wiley.com
    Epigenetic alternations in the SYP and DLG4 genes due to low-level methylmercury exposure during neuronal differentiation in vitro
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    Reduction of Global H3K27me3 Enhances HER2/ErbB2 Targeted Therapy
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    Hyperactivating EZH2 to augment H3K27me3 levels in regulatory T cells enhances immune suppression by driving early effector differentiation
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    Sex-dependent effects in the aged melanoma tumor microenvironment influence invasion and resistance to targeted therapy
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  21. Aug 2024
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    Feedforward cysteine regulation maintains melanoma differentiation state and limits metastatic spread
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    Thyroid hormone suppresses medulloblastoma progression through promoting terminal differentiation of tumor cells
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    sciencedirect.com/science/article/pii/S1535610824002733
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    The fork protection complex promotes parental histone recycling and epigenetic memory
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    sciencedirect.com/science/article/pii/S0092867424007773
  25. Jul 2024
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    The activity of early-life gene regulatory elements is hijacked in aging through pervasive AP-1-linked chromatin opening
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    H3 K27M and EZHIP Impede H3K27-Methylation Spreading by Inhibiting Allosterically Stimulated PRC2
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  28. Jun 2024
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    Spatially resolved epigenome sequencing via Tn5 transposition and deterministic DNA barcoding in tissue
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    The TERT Promoter is Polycomb-Repressed in Neuroblastoma Cells with Long Telomeres
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    DOT1L maintains NK cell phenotype and function for optimal tumor control
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    Lineage specification in glioblastoma is regulated by METTL7B
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    Defining cis-regulatory elements and transcription factors that control human cortical interneuron development
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  34. May 2024
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    Deletion of the mRNA endonuclease Regnase-1 promotes NK cell anti-tumor activity via OCT2-dependent transcription of Ifng
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    Enhanced ApcMin/+ adenoma formation after epithelial CUL4B deletion by recruitment of myeloid-derived suppressor cells
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  37. 52.53.155.43 52.53.155.43
    2024.02.25.581951v1.full-html.html
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    Identification of WNK1 as a therapeutic target to suppress IgH/MYC expression in multiple myeloma
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  39. Apr 2024
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Protein degradation of Lysine-specific demethylase 1 is mediated by Bre1 yet opposed by Lsd1-interacting lncRNAs during fly follicle development
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    The Drosophila Hippo pathway transcription factor Scalloped and its co-factors alter each other’s chromatin binding dynamics and transcription in vivo
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  42. www.embopress.org www.embopress.org
    The growth factor EPIREGULIN promotes basal progenitor cell proliferation in the developing neocortex
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  43. rupress.org rupress.org
    Tunable DNMT1 degradation reveals DNMT1/DNMT3B synergy in DNA methylation and genome organization
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      DOI: 10.1083/jcb.202307026

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    rupress.org/jcb/article/223/4/e202307026/276570/Tunable-DNMT1-degradation-reveals-DNMT1-DNMT3B
  44. www.embopress.org www.embopress.org
    The growth factor EPIREGULIN promotes basal progenitor cell proliferation in the developing neocortex
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    miR-217 regulates normal and tumor cell fate following induction of Endoplasmic Reticulum Stress
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      DOI: 10.1158/1541-7786.MCR-23-0676

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    aacrjournals.org/mcr/article/22/4/360/741846/miR-217-Regulates-Normal-and-Tumor-Cell-Fate
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    Nucleation and spreading maintain Polycomb domains every cell cycle
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    H2AK119ub1 differentially fine-tunes gene expression by modulating canonical PRC1- and H1-dependent chromatin compaction
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    Alternative splicing of histone demethylase Kdm6bb mediates temperature-induced sex reversal in the Nile tilapia
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    FAK-mediated phosphorylation at Y464 regulates p85β nuclear translocation to promote tumorigenesis of ccRCC by repressing RB1 expression
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  183. May 2022
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    Large-scale chromatin reorganization reactivates placenta-specific genes that drive cellular aging
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    XIST loss impairs mammary stem cell differentiation and increases tumorigenicity through Mediator hyperactivation
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    C/EBPδ-induced epigenetic changes control the dynamic gene transcription of S100a8 and S100a9
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    H3-K27M-mutant nucleosomes interact with MLL1 to shape the glioma epigenetic landscape
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    NSD1 mediates antagonism between SWI/SNF and polycomb complexes and is required for transcriptional activation upon EZH2 inhibition
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    Promoter and enhancer RNAs regulate chromatin reorganization and activation of miR-10b/HOXD locus, and neoplastic transformation in glioma
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    Maintenance of glutamine synthetase expression alleviates endotoxin-induced sepsis via alpha-ketoglutarate-mediated demethylation
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  197. Mar 2022
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    The KRAS-G12D mutation induces Metabolic Vulnerability in B-cell Acute Lymphoblastic Leukemia
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    Gene silencing by EZH2 suppresses TGF-β activity within the decidua to avert pregnancy-adverse wound healing at the maternal-fetal interface
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  208. Jan 2022
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  210. Dec 2021
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    TRACE generates fluorescent human reporter cell lines to characterize epigenetic pathways
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  214. Nov 2021
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  219. Oct 2021
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    Defining Proximity Proteomics of Histone Modifications by Antibody-mediated Protein A-APEX2 Labeling
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    Low folate induces abnormal neuronal maturation and DNA hypomethylation of neuronal differentiation-related genes in cultured mouse neural stem and progenitor cells
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