38 Matching Annotations
  1. Last 7 days
  2. www.sciencedirect.com www.sciencedirect.com
    Aerobic glycolysis but not GLS1-dependent glutamine metabolism is critical for anti-tumor immunity and response to checkpoint inhibition
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    1. scibot 22 Aug 2024
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    sciencedirect.com/science/article/pii/S2211124724009823
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    LAG-3 sustains TOX expression and regulates the CD94/NKG2-Qa-1b axis to govern exhausted CD8 T cell NK receptor expression and cytotoxicity
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    1. scibot 20 Aug 2024
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      DOI: 10.1016/j.cell.2024.07.018

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    sciencedirect.com/science/article/pii/S0092867424007785
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    LAG-3 and PD-1 synergize on CD8+ T cells to drive T cell exhaustion and hinder autocrine IFN-γ-dependent anti-tumor immunity
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    1. scibot 20 Aug 2024
      RRID:AB_2616907

      DOI: 10.1016/j.cell.2024.07.016

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    sciencedirect.com/science/article/pii/S0092867424007761
  5. Jul 2024
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    Preclinical study and phase II trial of adapting low-dose radiotherapy to immunotherapy in small cell lung cancer
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    1. scibot 19 Jul 2024
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    sciencedirect.com/science/article/pii/S2666634024002484
  7. Jun 2024
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sonogenetics-controlled synthetic designer cells for cancer therapy in tumor mouse models
    1
    1. scibot 08 Jun 2024
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      DOI: 10.1016/j.xcrm.2024.101513

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    ncbi.nlm.nih.gov/pmc/articles/PMC11148564/
  9. May 2024
  10. www.biorxiv.org www.biorxiv.org
    The latent stage of Toxoplasma gondii is targeted by the immune response and host protective
    1
    1. scibot 24 May 2024
      RRID:AB_2616907

      DOI: 10.1101/2024.03.05.583527

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    biorxiv.org/content/10.1101/2024.03.05.583527v1
  11. Apr 2024
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The diversity of inhibitory receptor co-expression patterns of exhausted CD8+ T cells in oropharyngeal carcinoma
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    1. scibot 28 Apr 2024
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      DOI: 10.1016/j.isci.2024.109668

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    ncbi.nlm.nih.gov/pmc/articles/PMC11035373/
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    Cancer SLC6A6-mediated taurine uptake transactivates immune checkpoint genes and induces exhaustion in CD8+ T cells
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    1. scibot 02 Apr 2024
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      DOI: 10.1016/j.cell.2024.03.011

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    sciencedirect.com/science/article/pii/S0092867424003039
  14. Feb 2024
  15. www.sciencedirect.com www.sciencedirect.com
    LAG-3- and CXCR5-expressing CD4 T cells display progenitor-like properties during chronic visceral leishmaniasis
    2
    1. scibot 29 Feb 2024
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      DOI: 10.1016/j.celrep.2024.113879

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    2. scibot 29 Feb 2024
      RRID:AB_2616907

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    sciencedirect.com/science/article/pii/S2211124724002079
  16. Dec 2023
  17. www.sciencedirect.com www.sciencedirect.com
    Stat5 opposes the transcription factor Tox and rewires exhausted CD8+ T cells toward durable effector-like states during chronic antigen exposure
    1
    1. scibot 17 Dec 2023
      RRID:AB_2616907

      DOI: 10.1016/j.immuni.2023.11.005

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    sciencedirect.com/science/article/pii/S1074761323004879
  18. Nov 2023
  19. www.sciencedirect.com www.sciencedirect.com
    The antitumor activities of anti-CD47 antibodies require Fc-FcγR interactions
    1
    1. scibot 28 Nov 2023
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    sciencedirect.com/science/article/pii/S153561082300363X
  20. Sep 2023
  21. www.sciencedirect.com www.sciencedirect.com
    Interferon-g-dependent interactions between tissue-intrinsic γδ T cells and tissue-infiltrating CD8 T cells limit acute contact dermatitis
    1
    1. scibot 29 Sep 2023
      RRID:AB_2616907

      DOI: 10.1016/j.jaci.2023.07.015

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    sciencedirect.com/science/article/pii/S0091674923009818
  22. Jun 2023
  23. www.sciencedirect.com www.sciencedirect.com
    The SWI/SNF chromatin remodeling complexes BAF and PBAF differentially regulate epigenetic transitions in exhausted CD8+ T cells
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    1. scibot 23 Jun 2023
      RRID:AB_2616907

      DOI: 10.1016/j.immuni.2023.05.008

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    sciencedirect.com/science/article/pii/S107476132300225X
  24. www.sciencedirect.com www.sciencedirect.com
    Intravenous heterologous prime-boost vaccination activates innate and adaptive immunity to promote tumor regression
    1
    1. scibot 08 Jun 2023
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      DOI: 10.1016/j.celrep.2023.112599

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    sciencedirect.com/science/article/pii/S2211124723006101
  25. May 2023
  26. www.sciencedirect.com www.sciencedirect.com
    Tailoring vascular phenotype through AAV therapy promotes anti-tumor immunity in glioma
    1
    1. scibot 12 May 2023
      RRID:AB_2616907

      DOI: 10.1016/j.ccell.2023.04.010

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    sciencedirect.com/science/article/pii/S1535610823001368
  27. Apr 2023
  28. www.sciencedirect.com www.sciencedirect.com
    Lymphocyte networks are dynamic cellular communities in the immunoregulatory landscape of lung adenocarcinoma
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    1. scibot 14 Apr 2023
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      DOI: 10.1016/j.ccell.2023.03.015

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    sciencedirect.com/science/article/pii/S1535610823000880
  29. Feb 2023
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The altering cellular components and function in tumor microenvironment during remissive and relapsed stages of anti-CD19 CAR T-cell treated lymphoma mice
    1
    1. scibot 10 Feb 2023
      RRID:AB_2616907

      DOI: 10.3389/fimmu.2023.1101769

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    ncbi.nlm.nih.gov/pmc/articles/PMC9905118/
  31. Jan 2023
  32. www.sciencedirect.com www.sciencedirect.com
    MHC class II-restricted antigen presentation is required to prevent dysfunction of cytotoxic T cells by blood-borne myeloids in brain tumors
    1
    1. scibot 19 Jan 2023
      RRID:AB_2616907

      DOI: 10.1016/j.ccell.2022.12.007

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    sciencedirect.com/science/article/pii/S1535610822005931
  33. Nov 2022
  34. www.cell.com www.cell.com
    Cancer immunotherapies transition endothelial cells into HEVs that generate TCF1+ T lymphocyte niches through a feed-forward loop
    1
    1. scibot 24 Nov 2022
      RRID:AB_2616907

      DOI: 10.1016/j.ccell.2022.11.002

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    cell.com/cancer-cell/fulltext/S1535-6108(22)00549-9
  35. www.sciencedirect.com www.sciencedirect.com
    CD8+ T cell metabolic rewiring defined by scRNA-seq identifies a critical role of ASNS expression dynamics in T cell differentiation
    1
    1. scibot 16 Nov 2022
      RRID:AB_2616907

      DOI: 10.1016/j.celrep.2022.111639

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    sciencedirect.com/science/article/pii/S2211124722015108
  36. www.sciencedirect.com www.sciencedirect.com
    Chronic type I interferon signaling promotes lipid-peroxidation-driven terminal CD8+ T cell exhaustion and curtails anti-PD-1 efficacy
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    1. scibot 16 Nov 2022
      RRID:AB_2616907

      DOI: 10.1016/j.celrep.2022.111647

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    sciencedirect.com/science/article/pii/S2211124722015182
  37. www.sciencedirect.com www.sciencedirect.com
    Cardiac myosin-specific autoimmune T cells contribute to immune-checkpoint-inhibitor-associated myocarditis
    1
    1. scibot 10 Nov 2022
      RRID:AB_2616907

      DOI: 10.1016/j.celrep.2022.111611

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    sciencedirect.com/science/article/pii/S2211124722014802
  38. Oct 2022
  39. www.cell.com www.cell.com
    Systemic vaccination induces CD8+ T cells and remodels the tumor microenvironment
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    1. scibot 27 Oct 2022
      RRID:AB_2616907

      DOI: 10.1016/j.cell.2022.10.006

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    cell.com/cell/fulltext/S0092-8674(22)01321-6
  40. 52.53.155.43 52.53.155.43
    IgA deficiency destabilizes immunological homeostasis towards intestinal microbiota and increases the risk of systemic immune dysregulation
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    1. scibot 27 Oct 2022
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      DOI: 10.1101/2021.08.20.21261620

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    52.53.155.43/62b31cea1ac090bac2ebe32e4dfd3474fee27f84/2021.08.20.21261620v1.full-html.html
  41. Jan 2022
  42. www.nature.com www.nature.com
    Adenosine 2A receptor and TIM3 suppress cytolytic killing of tumor cells via cytoskeletal polarization
    1
    1. scibot 15 Jan 2022
      RRID:AB_2616907

      DOI: 10.1038/s42003-021-02972-8

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    nature.com/articles/s42003-021-02972-8
  43. Sep 2021
  44. www.sciencedirect.com www.sciencedirect.com
    Antigen dominance hierarchies shape TCF1+ progenitor CD8 T cell phenotypes in tumors
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    1. scibot 18 Sep 2021
      RRID:AB_2616907

      DOI: 10.1016/j.cell.2021.08.020

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    sciencedirect.com/science/article/pii/S0092867421009946
  45. www.sciencedirect.com www.sciencedirect.com
    Conventional type I dendric cells maintain a reservoir of proliferative tumor-antigen specific TCF-1+ CD8+ T cells in tumor-draining lymph nodes
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    1. scibot 17 Sep 2021
      RRID:AB_2616907

      DOI: 10.1016/j.immuni.2021.08.026

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    sciencedirect.com/science/article/pii/S1074761321003605
  46. Aug 2021
  47. www.sciencedirect.com www.sciencedirect.com
    The CD155/TIGIT axis promotes and maintains immune evasion in neoantigen-expressing pancreatic cancer
    1
    1. scibot 15 Aug 2021
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      DOI: 10.1016/j.ccell.2021.07.007

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    sciencedirect.com/science/article/pii/S1535610821003846
  48. www.sciencedirect.com www.sciencedirect.com
    CXCR6 positions cytotoxic T cells to receive critical survival signals in the tumor microenvironment
    1
    1. scibot 15 Aug 2021
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      DOI: 10.1016/j.cell.2021.07.015

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    sciencedirect.com/science/article/pii/S0092867421008564
  49. Jul 2021
  50. www.sciencedirect.com www.sciencedirect.com
    Transforming growth factor-β-regulated mTOR activity preserves cellular metabolism to maintain long-term T cell responses in chronic infection
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    1. scibot 07 Jul 2021
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      DOI: 10.1016/j.immuni.2021.06.007

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    sciencedirect.com/science/article/pii/S107476132100251X
  51. Apr 2021
  52. www.sciencedirect.com www.sciencedirect.com
    The PD-1/PD-L1-Checkpoint Restrains T cell Immunity in Tumor-Draining Lymph Nodes
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    1. scibot 22 Apr 2021
      RRID:AB_2616907

      DOI: 10.1016/j.ccell.2020.09.001

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    sciencedirect.com/science/article/pii/S1535610820304323
  53. www.sciencedirect.com www.sciencedirect.com
    UTX promotes CD8+ T cell-mediated antiviral defenses but reduces T cell durability
    1
    1. scibot 15 Apr 2021
      RRID:AB_2616907

      DOI: 10.1016/j.celrep.2021.108966

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    sciencedirect.com/science/article/pii/S2211124721002801
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    In vivo CD8+ T cell CRISPR screening reveals control by Fli1 in infection and cancer
    1
    1. scibot 11 Apr 2021
      RRID:AB_2616907

      DOI: 10.1016/j.cell.2021.02.019

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    ncbi.nlm.nih.gov/pmc/articles/PMC8054351/
  55. www.sciencedirect.com www.sciencedirect.com
    Metabolic modulation by CDK4/6 inhibitor promotes chemokine-mediated recruitment of T cells into mammary tumors
    1
    1. scibot 07 Apr 2021
      RRID:AB_2616907

      DOI: 10.1016/j.celrep.2021.108944

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    sciencedirect.com/science/article/pii/S2211124721002588
  56. Sep 2020
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Developmental Relationships of Four Exhausted CD8+ T Cell Subsets Reveals Underlying Transcriptional and Epigenetic Landscape Control Mechanisms
    1
    1. scibot 09 Sep 2020
      RRID:AB_2616907

      DOI: 10.1016/j.immuni.2020.04.014

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    ncbi.nlm.nih.gov/pmc/articles/PMC8360766/
  58. www.sciencedirect.com www.sciencedirect.com
    The PD-1 Pathway Regulates Development and Function of Memory CD8+ T Cells following Respiratory Viral Infection
    1
    1. scibot 04 Sep 2020
      RRID:AB_2616907

      DOI: 10.1016/j.celrep.2020.107827

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    sciencedirect.com/science/article/pii/S2211124720308081
  59. Jan 2020
  60. www.sciencedirect.com www.sciencedirect.com
    TCF-1-Centered Transcriptional Network Drives an Effector versus Exhausted CD8 T Cell-Fate Decision
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    1. scibot 13 Jan 2020
      RRID:AB_2616907

      DOI: 10.1016/j.immuni.2019.09.013

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    sciencedirect.com/science/article/pii/S1074761319304091